NHS Evidence

This is a list of forthcoming guidelines, projects and reviews to assist you in establishing what information will shortly be available within your specialty.

NICE  

• Golimumab for the treatment of ankylosing spondylitis (February 2010)
• Shoulder resurfacing arthroplasty   (Summer 2010)
• The management of hip fractures in adults (June 2011)
• Management of femoral neck fractures  (June 2011)
• Pragmatic multi-centre randomised trial of surgical versus non-surgical treatment for proximal fracture of the humerus in adults   (2013)
• Preventing unintentional injuries among under 15s: outdoor play and leisure (October 2010)
• Osteoporotic fractures - denosumab (TBC)

SIGN
The following forthcoming guidelines are in development or in the process of being updated:

• Management of osteoporosis (Summer 2011) 

The Cochrane Library 2010, Issue 1.

• Botulinum toxin for low-back pain
• Botulinum toxin for shoulder pain
• Continuous passive motion therapy for preventing venous thromboembolism after total knee arthroplasty
• Endoscopic release for carpal tunnel syndrome
• Interventions for implementation of thromboprophylaxis in hospitalized medical and surgical patients at risk for venous thromboembolism
• Interventions for treating fifth metatarsal fractures in adults
• Intramedullary nailing for tibial shaft fractures in adults
• Intravenous zoledronate for postmenopausal osteoporosis
• Non-invasive brain stimulation techniques for chronic pain in adults
• Pharmacotherapy for the prevention of chronic pain after surgery in adults
• Single dose oral gabapentin for acute postoperative pain in adults
• Taping for knee osteoarthritis
• Thromboprophylaxis for trauma patients
• Topical phenytoin for treating pressure ulcers
• Topiramate for treating painful neuropathy or acute or chronic pain
• Total disc replacement for chronic low-back pain
• Vitamin K for the prevention and treatment of osteoporosis in post-menopausal women
  

New HTA Projects 

• Using evidence to reduce risk of healthcare acquired infection following primary hip replacement
• Comparison of close contact cast (CCC) technique to open surgical reduction and internal fixation (ORIF) in the treatment of unstable ankle fractures in patients over 60 years
• Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review
• Pragmatic multi-centre randomised trial of surgical versus non-surgical treatment for proximal fracture of the humerus in adults
• Management strategies for sciatica  
• Sugammadex for reversal of muscle relaxation in general anaesthesia
• A multi-centred randomised controlled trial of a primary-care based cognitive behavioural programme for low back pain (UK-Best)
• Managing Injuries of the Neck Trial (MINT)
• Risk factors for surgical wound infection 
• Assessment of surgical skills of trainees and consultants in the operating theatre
• A randomised controlled trial of different knee prostheses
• CRASH2 Trial, a large randomised placebo controlled trial among trauma patients with significant haemorrhage of the effects of an antifibrinolytic treatment on death and transfusion requirement
• The clinical and cost-effectiveness of surgical (arthroscopic or open) versus rest then exercise management for tears of the rotator cuff (UKUFF trial)
• Total or Partial Knee Arthroplasty Trial (TOPKAT)
• Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation
• The cost-effectiveness of investigation and hospital admission for minor (GCS 13-15) head injury
• A multicentre, randomised, placebo controlled trial of lactic acid bacteria in prevention of antibiotic-associated diarrhoea (AAD) & Clostridium difficile diarrhoea (CDD) in patients aged 65 years & over admitted to hospital and receiving antibiotics
• Care of older people who fall: evaluation of the clinical and cost effectiveness of new protocols for emergency ambulance personnel to assess and refer to appropriate community based care
• CATheter Infections in Children - the CATCH trial
• A randomised phase III trial of Docetaxel plus Prednisolone vs. Docetaxel with Prednisolone plus either Zoledronic acid, Strontium-89 or both agents combined (TRAPEZE)
• Comparison of close contact cast (CCC) technique to open surgical reduction and internal fixation (ORIF) in the treatment of unstable ankle fractures in patients over 60 years
• Total or Partial Knee Arthroplasty Trial (TOPKAT)
• Denosumab for osteoporotic fractures in post menopausal women primary and secondary prevention