Bipolar Disorder Knowledge Week 2006
Link to the 2007 Bipolar Disorder Annual Evidence Update Contents page
If this is your first visit, please read the introduction.
If you are looking for a general overview of treatment for bipolar disorder, please read our treatment overview (PDF).
We have produced a number of evidence-based summaries for various treatments that are commonly used in bipolar disorder. This is not a comprehensive list, but does provide access to all of the important systematic reviews, meta-analyses and guidelines in this area to date (November 2006).
Acute mania or mixed episode (Bipolar I)
- Lithium (brief, detailed, guidelines)
- Olanzapine (brief, detailed, guidelines)
- Valproate (brief, detailed, guidelines)
- Carbamazepine (brief, detailed, guidelines)
- Risperidone (brief, detailed, guidelines)
- Benzodiazepines (brief, detailed, guidelines)
- Quetiapine (brief, detailed, guidelines)
Acute depressive episode (Bipolar I or II)
Maintenance treatment
- Lithium (brief, detailed, guidelines)
- Valproate (brief, detailed, guidelines)
- Olanzapine (brief, detailed, guidelines)
- Risperidone (brief, detailed, guidelines)
- Lamotrigine (brief, detailed, guidelines)
- Psychosocial interventions (brief, detailed, guidelines)
- Carbamazepine (brief, detailed, guidelines)
Self-harm and suicide
Reproductive health issues
Substance misuse
Children and adolescents
Key
The above menu provides access to 3 different types of evidence summary:
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Brief summary
These 1-page documents provide a brief overview of the current evidence from systematic reviews and our suggestions for research priorities. If you just want a quick answer to a simple question, this is a good place to start.
Note: these summaries do not contain references.
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Detailed summary
We have adapted the EPICOT system (ref 1) to write our detailed summaries, which provide more information about systematic reviews. Here we detail the specific populations, interventions and outcomes that the research focuses on, as well as highlighting the sponsors of the research. If you are interested in the detailed statistical information that sits behind the evidence, you will find it here in our downloadable PDF evidence tables, which present the quality and summarise the findings of systematic reviews.
Note: these summaries contain references.
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Guidelines summary
There are a number of guidelines for managing and treating bipolar disorder, so we have summarised these for each intervention and presented the key areas of agreement and disagreement.
Note: these summaries contain references.
References
1. Brown, P. et al How to formulate research recommendations. BMJ 2006; 333; 804-806.
