UK Database of Uncertainties about the Effects of Treatments (DUETs) Resource List
"As needed" versus continuously scheduled antimuscarinic therapy for urinary incontinence
(1?3)?-D-glucan testing for the detection of invasive fungal infections in immunocompromised patients
11C-PIB-PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
308nm excimer laser for repigmentation in vitiligo
308nm excimer laser plus topical calcipotriol for repigmentation in vitiligo
308nm excimer laser plus topical hydrocortisone 17-butyrate for repigmentation in vitiligo
5-ASA for management of symptomatic uncomplicated diverticular disease (SUDD)
A 35 yr old with DVT has just stopped warfarin after 6 months. Is there any evidence for him taking Aspirin (75mg-300mg) life-long to prevent recurrence?
A comparison of endoscopic and surgical treatment of strictures in patients with Crohn's disease
A co-ordinated approach of primary and secondary care in the early diagnosis and management of schizophrenia
A randomised controlled trial of outcomes in incidental venous thromboembolism (an observational study and follow-up RCT of treatment versus no treatment if indicated).
A review of the effectiveness of oral health promotion activities among elderly people
Abatacept for rheumatoid arthritis
Abdominal decompression for suspected fetal compromise/pre-eclampsia
Abdominal decompression in normal pregnancy
Abdominal drainage after appendectomy for complicated appendicitis
Abdominal drainage versus no drainage post gastrectomy for gastric cancer
Abdominal lift for laparoscopic cholecystectomy
Absence of carious lesions at margins of glass-ionomer and amalgam restorations
Acamprosate for alcohol dependence
Acceptability, efficacy and safety of pharmacological interventions for cocaine dependence: an overview of Cochrane reviews
ACE inhibitors for the reduction of portal pressure in Child-Pugh class A cirrhosis
Acellular vaccines for preventing whooping cough in children
Acetylcholinesterase inhibitor treatment for myasthenia gravis
Acetylcholinesterase inhibitors and memantine for the treatment of psychotic symptoms in dementia over six months
Acetylcholinesterase inhibitors for schizophrenia
Acetylcholinesterase inhibitors for schizophrenia
Acid reflux treatment for hoarseness
Acoustic CR Neuromodulation is a commercial device for 'brain training'. Is it effective for people with tinnitus?
Action plans for chronic obstructive pulmonary disease
Action plans with limited patient education only for exacerbations of chronic obstructive pulmonary disease
Active case finding in contacts of people with tuberculosis
Active chest compression-decompression for cardiopulmonary resuscitation
Active cycle of breathing technique for cystic fibrosis
Active management of spontaneous labour versus routine care in women who have had one or more previous caesarean sections
Active placebos versus antidepressants for depression
Active specific immunotherapy for malignant melanoma
Active versus passive parental consent for improving participant recruitment and outcomes in studies targeting children
Activity restriction for short-term and medium-term outcomes following mild traumatic brain injury
Acupoint stimulation for postoperative ileus ?following gastrointestinal surgery
Acupressure for motion sickness
Acupuncture and moxibustion for acne
Acupuncture and related interventions (acupressure, laser therapy or electrostimulation) for smoking cessation
Acupuncture and related interventions for treating plantar heel pain in adults
Acupuncture for acute management and rehabilitation of traumatic brain injury
Acupuncture for adults with type 2 diabetes mellitus
Acupuncture for asthma
Acupuncture for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents
Acupuncture for autism spectrum disorders (ASD)
Acupuncture for Bell's palsy
Acupuncture for bladder dysfunction after spinal cord injury
Acupuncture for chronic asthma
Acupuncture for chronic constipation
Acupuncture for depression
Acupuncture for epilepsy
Acupuncture for female subfertility
Acupuncture for glaucoma
Acupuncture for hypoxic ischemic encephalopathy in neonates
Acupuncture for insomnia
Acupuncture for Ménière's Syndrome
Acupuncture for mumps in children
Acupuncture for nocturnal enuresis
Acupuncture for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Acupuncture for pain in endometriosis
Acupuncture for polycystic ovarian syndrome
Acupuncture for primary hypercholesterolaemia
Acupuncture for rheumatoid arthritis
Acupuncture for schizophrenia
Acupuncture for schizophrenia
Acupuncture for slowing the progression of myopia in children and adolescents
Acupuncture for tinnitus
Acupuncture for treating irradiation-induced xerostomia in head and neck cancer
Acupuncture for treatment of irritable bowel syndrome
Acupuncture for urinary incontinence in adults without neurological disease
Acupuncture for xerostomia
Acupuncture in poststroke rehabilitation
Acupuncture or acupressure for pain management in labour
Acupuncture vs routine care for tension-type headache
Acupuncture vs sham treatments for tension-type headache
Acupuncture, QiGong, graded exercise, or other alternative therapies for Lyme disease
Acute day hospitals compared to other acute service provision, such as crisis resolution and home treatment teams for serious mental illness
Adding leukotriene antagonists to inhaled corticosteroids in people with mild to moderate, persistent asthma
Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma
Addition of inhaled anticholinergics to beta2-agonists for children with acute asthma in hospital
Addition of intravenous aminophylline to inhaled beta2-agonists in adults with acute asthma
Addition of intravenous beta2-agonists to inhaled beta2-agonists for acute asthma
Additional bedtime H2-receptor antagonist for the control of nocturnal gastric acid breakthrough
Additional exercise therapy for the recovery of function after stroke
Adenosine A2A receptor antagonist istradefylline for levodopa-induced complications in Parkinson's disease
Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2 diabetes mellitus
Adenotonsillectomy for obstructive sleep apnoea in children
Adjunctive antioxidants for bipolar disorder
Adjunctive antithyroid drugs in radioiodine therapy for hyperthyroidism
Adjunctive hyperbaric oxygen for necrotizing fasciitis
Adjusting the pH of lidocaine for reducing pain on injection
Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer
Adjuvant antiviral therapy for recurrent respiratory papillomatosis
Adjuvant chemotherapy after concurrent chemoradiation for locally advanced cervical cancer
Adjuvant chemotherapy for endometrial cancer after hysterectomy
Adjuvant chemotherapy for small intestine adenocarcinoma
Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis
Adjuvant gonadotropin-releasing hormone analogues for the prevention of chemotherapy induced premature ovarian failure in premenopausal women
Adjuvant platinum-based chemotherapy for early stage cervical cancer
Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosarcoma
Adjuvant radiotherapy following radical prostatectomy for pathologic T3 or margin-positive prostate cancer
Adjuvant radiotherapy following radical prostatectomy for prostate cancer
Adjuvant radiotherapy for stage I endometrial cancer
Adjuvant therapy for completely resected stage II colon cancer
Adjuvant therapy for the treatment of advanced borderline ovarian tumours
Adrenaline auto-injectors for the treatment of anaphylaxis with and without cardiovascular collapse in the community
Adrenergic drugs for urinary incontinence in adults
Adrenergic drugs for urinary incontinence in comparision with alternative approaches to the care of people with stress urinary incontinence
Advance misoprostol distribution for preventing and treating postpartum haemorrhage
Advance treatment directives for people with severe mental illness
Advanced sperm selection techniques for assisted reproduction
Advanced trauma life support training for ambulance crews
Advantages and disadvantages of alternative types of oestrogen therapy in treating post-menopausal women with urinary incontinence.
Adventitial sheathotomy in branch retinal vein occlusion
Adverse effects in women taking Pentoxifylline for the treatment of endometriosis?
Adverse effects of anti-epileptic drugs medication in pregnancy
Adverse effects of biologics: a network meta-analysis and Cochrane overview
Advising patients to increase fluid intake for treating acute respiratory infections
Air pollution: no evidence was identified regarding asthma and indoor air pollutants, such as volatile organic compounds, formaldehyde or nitrogen oxide
Airway clearance techniques for chronic obstructive pulmonary disease
Alarms, desmopressin or tricyclic drug treatment as the first line management of nocturnal enuresis in children
Alcohol and drug screening of occupational drivers for preventing work-related injury
Alcohol intake reduction for controlling hypertension
Aldosterone blockers for heart failure
Alemtuzumab for patients with chronic lymphocytic leukaemia
Alexander technique for chronic asthma
Alginate dressings for healing diabetic foot ulcers
Alginate dressings for venous leg ulcers
Alginate dressings for venous leg ulcers
Allergen injection immunotherapy for perennial allergic rhinitis
Allergen-specific oral immunotherapy for peanut allergy
Allicin for Lyme diseaase
Allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia (ALL) in first complete remission
Allogeneic stem cell transplantation versus conventional therapy for advanced primary cutaneous T-cell lymphoma
Allogeneic stem cell transplantation with matched sibling donor versus autologous stem cell transplantation for newly diagnosed Multiple Myeloma
Allopurinol for preventing mortality and morbidity in newborn infants with hypoxic-ischaemic encephalopathy
Almitrine-Raubasine combination for dementia
Aloe vera for treating acute and chronic wounds
Aloe vera for treating acute and chronic wounds
Alpha blockers for removal of urethral catheter after acute urinary retention in men
Alpha2 adrenergic agonists for attention deficit hyperactivity disorder (ADHD)
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients
Alpha-foetoprotein and/or liver ultrasonography for screening of hepatocellular carcinoma in patients with chronic hepatitis B
Alprazolam for depression
Alprazolam for essential tremor
Altered blood pH for Lyme disease
Altered dietary salt intake for chronic kidney disease
Altered dietary salt intake for preventing and treating diabetic kidney disease
Alternating different antibiotics for Lyme disease
Alternative and complementary therapies for psoriasis
Alternative injectable materials for vocal fold medialisation in unilateral vocal fold paralysis
Alternative testing sites to increase the number of people who are tested and treated for hepatitis B and C
Alternative versus conventional institutional settings for birth
Amantadine and rimantadine for influenza A in children and the elderly
Amantadine for depression
Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome
Amifostine for salivary glands in high-dose radioactive iodine treated differentiated thyroid cancer
Amino acid, fat emulsion and energy supplementation for severe pneumonia in the elderly
Aminoadamantanes for chronic hepatitis C
Aminosalicylates for induction of remission or response in Crohn's disease
Amitriptyline for depression
Amitriptyline for neuropathic pain and fibromyalgia in adults
Amitriptyline versus placebo for major depressive disorder
Amnioinfusion for improving fetal outcomes after preterm prelabour rupture of membranes
Amnioinfusion for potential or suspected umbilical cord compression in labour
Amnioinfusion for preterm premature rupture of membranes
Amniotic membrane transplantation for acute ocular burns
Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents
Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function
Amplification for auditory neuropathy
Amplification with hearing aids for patients with tinnitus and co-existing hearing loss
An overview of reviews evaluating the effectiveness of financial incentives in changing healthcare professional behaviours and patient outcomes
Anaesthesia for evacuation of incomplete miscarriage
Anaesthesia for treating distal radial fracture in adults
Anakinra compared to other biological therapies for rheumatoid arthritis
Analgesia for amniocentesis or chorionic villus sampling
Analgesia for patients undergoing shockwave lithotripsy for urinary stones
Analgesia for relief of pain due to uterine cramping/involution after birth
Analimumab for fistulizing Crohn's disease
Andrenoceptor agonists for urinary incontinence
Androgens (dehydroepiandrosterone or testosterone) in women undergoing assisted reproduction
Angiogenesis inhibitors for the treatment of ovarian cancer
Angiogenesis-inhibitors for metastatic thyroid cancer
Angioplasty versus stenting for subclavian artery stenosis
Angiotensin converting enzyme (ACE) gene polymorphism (ACEI/D) in hypertensive adults with ACE inhibitor-induced cough
Angiotensin receptor blockers for heart failure
Angiotensin receptor blockers for heart failure
Angiotensin receptor blockers for the reduction of portal pressure in Child-Pugh class A cirrhosis
Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease
Annual Chest X-Rays in successfully treated cases of Head & Neck cancer
Antenatal breast milk expression by women with diabetes for improving infant outcomes
Antenatal breastfeeding education for increasing breastfeeding duration
Antenatal cardiotocography for fetal assessment
Antenatal care programmes to reduce infant mortality and preterm birth in socially disadvantaged and vulnerable women in high-income countries.
Antenatal dietary advice and supplementation to increase energy and protein intake
Antenatal interventions for preventing the transmission of cytomegalovirus (CMV) from the mother to fetus during pregnancy and adverse outcomes in the congenitally infected infant
Antenatal interventions for reducing weight in obese women for improving pregnancy outcome
Antenatal perineal massage for reducing perineal trauma
Antenatal screening for haemoglobinopathies in primary care: a cluster randomised trial to inform a simulation model
Anti-adhesion molecules for Crohn's disease
Anti-angiogenic therapies for metastatic colorectal cancer in patients with cardiovascular disease or a history of prior thromboembolic events
Antiangiogenic therapy with anti-vascular endothelial growth factor (anti-VEGF) modalities to treat diabetic macular oedema
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration
Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation
Antibiotic gels for the prevention of Lyme disease in patients with tick bites
Antibiotic lock for the prevention of catheter-related sepsis in neonates
Antibiotic prophylaxis for hernia repair.
Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy
Antibiotic prophylaxis for preventing infection in open finger fractures
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery
Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures
Antibiotic prophylaxis for surgical site infection in patients undergoing liver transplantation
Antibiotic prophylaxis for the prevention of Methicillin resistant Staphylococcus aureus (MRSA) infections and related complications in surgical patients
Antibiotic prophylaxis for transrectal prostate biopsy
Antibiotic prophylaxis for transurethral urological procedures
Antibiotic regimens for the empirical treatment of newborn infants with necrotising enterocolitis
Antibiotic therapy for pelvic inflammatory disease (PID)
Antibiotic therapy for preventing infections in patients with acute stroke
Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) in non surgical wounds
Antibiotic therapy for the treatment of Methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds
Antibiotic therapy for treatment of infective endocarditis
Antibiotic treatment based on clinical suspicion for Lyme disease after a negative serological test
Antibiotic treatment based on clinical suspicion versus waiting for serology results in possible Lyme disease
Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation
Antibiotic treatment for nontuberculous mycobacteria lung infection in people with cystic fibrosis
Antibiotic treatment for nontuberculous mycobacteria lung infection in people with cystic fibrosis
Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis
Antibiotics for acute laryngitis in adults
Antibiotics for acute maxillary sinusitis
Antibiotics for acute otitis media in children
Antibiotics for acute otitis media in children; effects on subgroups
Antibiotics for brain abscesses in people with cyanotic congenital heart disease
Antibiotics for chronic osteomyelitis in adults
Antibiotics for clinically diagnosed acute rhinosinusitis in adults
Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children
Antibiotics for exacerbations of chronic obstructive pulmonary disease
Antibiotics for infection prevention after excision of the cervical transformation zone
Antibiotics for leptospirosis
Antibiotics for mastitis in breastfeeding women
Antibiotics for meconium-stained amniotic fluid in labour for preventing maternal and neonatal infections
Antibiotics for otitis media with effusion in children
Antibiotics for persistent cough or wheeze following acute bronchiolitis in children
Antibiotics for persistent nasal discharge (rhinosinusitis) in children
Antibiotics for preventing meningococcal infections
Antibiotics for prolonged moist cough in children
Antibiotics for the prophylaxis of bacterial endocarditis in dentistry
Antibiotics for trachoma
Antibiotics for treating acute chest syndrome in people with sickle cell disease
Antibiotics for treating bacterial vaginosis in pregnancy
Antibiotics for treating community acquired pneumonia in people with sickle cell disease
Antibiotics for treating human brucellosis
Antibiotics for treating lower urinary tract infection in children
Antibiotics for treating osteomyelitis in people with sickle cell disease
Antibiotics for treating salmonella gut infections
Antibiotics for uncomplicated diverticulitis
Antibiotics in 'clean' foot ulcers in people with diabetes
Antibiotics plus colony stimulating factors versus antibiotics alone for the prevention of infections in cancer patients receiving myelosuppressive chemotherapy or haematopoetic stem cell transplantation
Antibiotics prior to embryo transfer in ART
Antibiotics to prevent complications following tooth extractions
Antibiotics to reduce post-tonsillectomy morbidity
Antibiotics versus control for toxoplasma retinochoroiditis
Antibiotics versus placebo for acute bacterial conjunctivitis
Antibody induction versus corticosteroid induction for liver transplant recipients
Antibody induction versus placebo, no induction, or another type of antibody induction for liver transplant recipients
Anticholinergic drugs for nocturnal enuresis (oxybutynin, tolterodine, hyoscyamine)
Anticholinergic drugs versus non-drug active therapies for non-neurogenic overactive bladder syndrome in adults
Anticholinergic drugs, compared to other drugs for overactive bladder symptoms
Anticholinergic medication for neuroleptic-induced tardive dyskinesia
Anticholinergic therapy for acute asthma in children
Anticholinergic therapy for acute asthma in children
Anticholinergic therapy for acute asthma in children
Anticholinergics for neuroleptic-induced acute akathisia
Anticholinergics for neuroleptic-induced parkinsonism
Anticholinergics for urinary symptoms in multiple sclerosis
Anticholinerigic drugs, bladder training or the combination of the two for the management of overactive bladder symptoms
Anticoagulant treatment for subsegmental pulmonary embolism
Anticoagulation for cerebral venous sinus thrombosis
Anticoagulation for heart failure in sinus rhythm
Anticoagulation for patients with cancer and central venous catheters
Anticoagulation for the initial treatment of venous thromboembolism in patients with cancer
Anticonvulsants for tinnitus
Anticonvulsants for tinnitus
Anti-cytomegalovirus treatment in patients with ulcerative colitis
Anti-D administration after spontaneous miscarriage for preventing Rhesus alloimmunisation
Anti-D administration after spontaneous miscarriage for preventing Rhesus alloimmunisation
Anti-D administration in pregnancy for preventing Rhesus alloimmunisation
Antidepressant drugs for older people
Antidepressant medication for children with depression
Antidepressants for agitation and psychosis in dementia
Antidepressants for cocaine dependence and problematic cocaine use
Antidepressants for depressed elderly
Antidepressants for pain management in rheumatoid arthritis
Antidepressants for painful rheumatological conditions
Antidepressants for patients with tinnitus
Antidepressants for people with both schizophrenia and depression
Antidepressants for the negative symptoms of schizophrenia
Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescents
Antidepressants for tinnitus
Antidepressants plus benzodiazepines for major depression
Antidepressants versus placebo for depression in primary care
Antidepressants versus placebo for the depressed elderly
Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood
Anti-epileptic drugs (AEDs) and the risk of teratogenic effects when taken during pregnancy
Antiepileptic drugs as prophylaxis for post-craniotomy seizures
Antiepileptic drugs for preventing seizures in people with brain tumors
Antiepileptic drugs for the primary and secondary prevention of seizures after intracranial venous thrombosis
Antiepileptic drugs for the primary and secondary prevention of seizures after stroke
Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis
Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy
Antiepileptic drugs for treating seizures in adults with brain tumours
Antiepileptic treatments for seizures in multiple sclerosis
Antifibrinolytic amino acids for upper gastrointestinal bleeding in patients with acute or chronic liver disease
Antifibrinolytic drugs for acute traumatic injury
Antifibrinolytic therapy to reduce haemoptysis from any cause
Anti-fibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological disorders
Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis
Antifungal therapy for newborn infants with invasive fungal infection
Antiglucocorticoid and related treatments for psychosis
Antihistamines for dermatomal itching associated with Lyme disease
Antihypertensive agents for preventing diabetic kidney disease
Anti-hypertensive drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies and clinical trials
Anti-IgE for chronic asthma in adults and children
Anti-IgE therapy for allergic bronchopulmonary aspergillosis in people with cystic fibrosis
Anti-IL-17 monoclonal antibody for induction of remission in Crohn's disease
Anti-inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis-related arthritis
Anti-inflammatory drugs and risk of Parkinson disease
Anti-inflammatory nasal sprays for the prevention of acute otitis media
Anti-inflammatory treatment for carditis in acute rheumatic fever
Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
Antimicrobials for treating symptomatic non-typhoidal Salmonella infection
Antimuscarinic drugs for urinary incontinence for frail and institutionalised older people
Antimuscarinic drugs for urinary incontinence in people with dementia and/or Parkinsons disease, and frail older person taking cholinergic agents for dementia
Antimuscarinic medication and inpatient bladder retraining for urinary incontinence
Antioxidant micronutrients for lung disease in cystic fibrosis
Antioxidant multivitamin supplements in malnourished people to slow progression of age-related macular degeneration to more severe stages of the disease
Anti-oxidant pool (vitamins C & E, alpha-lipoic acid and polyunsaturated fats) plus narrow band UVB for repigmentation in vitiligo
Antioxidant supplements for liver diseases
Antioxidant supplements for liver diseases
Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration
Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration
Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract
Antioxidants and other pharmacological treatments for Friedreich ataxia
Antioxidants as adjuvants to other drugs in liver diseases
Antioxidants for chronic kidney disease
Antioxidants for Friedreich ataxia
Antioxidants for idiopathic sudden sensorineural hearing loss
Antiplatelet agents and anticoagulants for hypertension
Antiplatelet agents for chronic kidney disease
Antiplatelet agents for intermittent claudication
Antiplatelet agents including aspirin for the prevention of coronary heart disease (CHD) in diabetes with particular attention to high risk groups (e.g. patients with renal disease and hypertensive disease)
Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm
Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment
Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia
Antiplatelet therapy for subarachnoid haemorrhage.
Antipsychotic drug discontinuation phenomena
Antipsychotic drug treatment for elderly people with late-onset schizophrenia
Antipsychotic drugs for older people with schizophrenia
Antipsychotic drugs for younger people with psychosis
Antipsychotic drugs in first episode of schizophrenia
Antipsychotic medication for childhood-onset schizophrenia
Antipsychotic medication for early episode schizophrenia
Antipsychotic medication for elderly people with schizophrenia
Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems
Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems.
Antipyretic measures for treating fever in malaria
Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals
Antiretroviral therapy for prevention of HIV transmission in HIV-discordant couples
Antispasmodics for labour
Antistreptococcal interventions for guttate and chronic plaque psoriasis
Antithrombin III to decrease blood loss and blood transfusion requirements for liver resection
Antithyroid drugs plus radioactive iodine for primary hyperthryoidism
Antithyroid drugs plus thyroxine compared with antithyroid drugs alone for primary hyperthyroidism
Antithyroid treatment for subclinical hyperthyroidism
Anti-TNF agents for paediatric psoriasis
Anti-TNF agents for prevention of post-operative recurrence of Crohn's disease
Anti-TNF therapy in inflammatory bowel disease during conception
Anti-TNF-a treatment for pelvic pain associated with endometriosis
Anti-vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity
Anti-vascular endothelial growth factor agents for treatment of macular edema secondary to central retinal vein occlusion
Anti-vascular endothelial growth factor for branch retinal vein occlusion
Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion
Anti-vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion
Anti-vascular endothelial growth factor for neovascular glaucoma
Anti-vascular endothelial growth factor for prevention of postoperative vitreous cavity haemorrhage after vitrectomy for proliferative diabetic retinopathy
Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients
Antiviral prophylactic intervention for chronic hepatitis C virus in patients undergoing liver transplantation
Antiviral therapy for chronic hepatitis C in injecting drug users
Antiviral therapy for chronic hepatitis C in patients coinfected with HBV
Antiviral therapy for chronic hepatitis C in patients coinfected with HIV
Antiviral therapy for chronic hepatitis C in patients who did not respond to treatment with peginterferon plus ribavirin or relapsed following it
Antiviral therapy for chronic hepatitis C in patients with haemophilia
Antiviral therapy for chronic hepatitis C in patients with histologically mild disease
Antiviral therapy for chronic hepatitis C in patients with normal ALT levels
Antiviral therapy for hepatitis C patients without rapid virological response
Antiviral therapy for recurrent liver graft infection with hepatitis C virus
Antiviral therapy in patients with Hepatitis B virus DNA levels of >=20,000 IU/mL and normal ALT levels
Antiviral treatment and other therapeutic interventions for herpes simplex viRCs epithelial keratitis
Antivirals alone or combined with immunoglobulin for the prevention of hepatitis B recurrence after liver transplantation
Antivirals for idiopathic sudden sensorineural hearing loss
Any multivitamin or single component antioxidant supplement for age-related macular degeneration to slow or prevent progression
Any versus no fluid resuscitation in acute upper gastrointestinal haemorrhage
Appendectomy versus antibiotic treatment for acute appendicitis
Approaches to ensure fathers and grandparents help protect or improve the social and emotional wellbeing of vulnerable children aged under 5 years
Appropriate duration and optimal treatment regimen of anti-vascular endothelial growth factor modalities for exudative age-related macular degeneration
Appropriate duration and optimal treatment regimen of anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration
Appropriateness of US guidelines for early Lyme disease in treating UK and European cases
Aprotinin to decrease blood loss and blood transfusion requirements for liver resection
Aquatic exercise for knee or hip osteoarthritis
Aqueous shunts for glaucoma
Are alternative treatments helpful for asthma in children?
Are Angiotensin converting enzyme inhibitors (ACE inhibitors) more effective than Angiotensin II receptor antagonists (AIIRA's) in reducing progression of kidney disease and reducing mortality in people with diabetes?
Are antipsychotic drugs more effective when combined with a mood stabilizer in severe mental illness?
Are antipsychotics bad for my sleep
Are any complementary therapies effective in preventing the severity, frequency and progression of attacks of Ménière's disease?
Are any of the various available alternative therapies effective in the management of tinnitus?
Are botulinum toxin injections effective in reducing enuresis?
Are botulinum toxin injections in patients previously treated with bulking agents for stress urinary incontinence associated with adverse outcomes?
Are breathing exercises helpful for asthma in children?
Are breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises useful for asthma?
Are calcineurin inhibitors (tacrolimus or pimecrolimus) effective in treating vitiligo?
Are calcineurin inhibitors (tacrolimus or pimecrolimus) more effective if used to treat vitiligo when it first appears, rather than waiting until the disease has spread?
Are calcineurin inhibitors (tacrolimus or pimecrolimus) more effective in treating vitiligo when combined with steroid creams?
Are calcineurin inhibitors applied to the skin safe to use in combination with sun exposure for people with eczema?
Are Chinese herbal medicine Huangqi type formulations effective as treatment for nephrotic syndrome?
Are complementary and alternative (CAM) therapies safe for prostate cancer?
Are complementary and alternative therapies useful following treatment for men living for prostate cancer?
Are complementary therapies effective in the treatment of stress urinary incontinence?
Are complex multi-dose insulin regimes a safe and effective treatment in elderly people with Type 1 and Type 2 diabetes?
Are cranberry juice and other alternative or complimentary therapies effective in reducing urinary tract infections?
Are creams and ointments (e.g. steroid creams) more effective when combined with natural sunlight?
Are daycare units cost effective compared with emergency settings for treating patients with an acute painful sickle cell episode?
Are disposable catheters more or less accepatable than reusable catheters in terms of effective bladder management, patient experience and urinary tract infections?
Are doctors favouring different drugs for the same condition on the basis of financial incentives?
Are Enbrel (etanercept) anti-inflammatory injections a safe and effective treatment for severe asthma uncontrolled by oral and inhaled steroids?
Are exercise-based therapies successful in the treatment of urge urinary incontinence?
Are exposure therapy and/or systematic desensitisation safe and effective treatments for misophonia?
Are general practice teams useful in crisis management of people with schizophrenia?
Are genetic factors a good tool to predict prognosis of prostate cancer?
Are home-based exercises given to patients with balance disorders effective?
Are homeopathic medicines helpful in asthma?
Are immunosuppressive treatments effective for focal segmental glomerulosclerosis in adults?
Are insulin analogues a safe long-term treatment for adults with Type 1 and Type 2 diabetes?
Are insulin analogues a safe long-term treatment for children with Type 1 and Type 2 diabetes?
Are insulin analogues a safe long-term treatment for pregnant women with Type 1 and Type 2 diabetes and their unborn babies?
Are insulin analogues a safe long-term treatment for those with complications and the elderly with Type 1 and Type 2 diabetes?
Are insulin analogues a safe long-term treatment for Type 1 and Type 2 diabetes?
Are Insulin Pens accurate at delivering insulin, even in small doses?
Are moisturisers effective in stopping the spread of vitiligo?
Are mortality rates and complication rates for the human, analogues and animal insulin's different?
Are natural thermal mineral waters effective in knee osteoarthritis?
Are novel immunotherapy treatments such as banked HLA-matched (human leucocyte antigen) cytotoxic T lymphocytes (CTLs) effective in kidney transplant patients with Post Transplant Lymphoproliferative Disorders?
Are PET scans accurate for staging of prostate cancer?
Are phosphodiesterase inhibitors safe in people with diabetes mellitus who have coronary artery disease?
Are postmanoeuvre activity restrictions necessary after canalith repositioning procedure?
Are prophylactic antibiotics more effective than lifestyle advice for the reduction of urinary tract infections?
Are proven risk reductions in macrovascular disease in diabetes when employed simultaneously, additive, multiplicative or otherwise?
Are psychological interventions less effective in older people with severe mental illness?
Are psychological therapies helpful for asthma compared to drugs?
Are rapid-acting insulin analogues beneficial in children and adolescents?
Are saunas and swimming good for controlling asthma?
Are side effects of antipsychotics proportional to their effectiveness?
Are social activities beneficial for schizophrenia?
Are steroid creams more effective if used to treat vitiligo when it first appears, rather than waiting until the disease has spread?
Are steroids better taken by inhaling them or in tablet form for controlling asthma in children?
Are stress management techniques helpful in patients with balance disorders
Are the adverse effects of antipsychotic drugs worse in the morning?
Are the drugs used to treat maternal asthma harmful to the infant during breastfeeding?
Are the phosphodiesterase inhibitors as effective as other therapeutic options to treat erectile dysfunction?
Are therapeutic doses of low-molecular-weight heparin (LMWH) effective, compared with prophylactic doses of LMWH, in reducing the length of stay in hospital of patients with an acute painful sickle cell episode?
Are there advantages of taking a squirt of Ventolin prior to the regular twice daily Flixotide dose?
Are there age related clinical indicators that limit the use of radiotherapy and chemo therapy for prostate cancer?
Are there alternative treatments to hormone therapy that have less impact on Quality of Life for men with prostate cancer?
Are there any advantages of combined antihistamine preparations (e.g. Arlevert) for the management of Ménière's disease?
Are there any alternatives to drugs which help in asthma?
Are there any complementary therapies or supplements that help in asthma?
Are there any dietary measures that can prevent prostate cancer or slow its progression?
Are there any dietary measures that can prevent prostate cancer or slow its progression?
Are there any effective drug treatments for prostate cancer that would replace the need for surgery and/or radiotherapy?
Are there any effective interventions for the ear pressure symptoms in Ménière's disease?
Are there any effective surgical interventions for asthma?
Are there any effective treatments for a prostate cancer patient with urinary incontinence?
Are there any interventions to help prostate cancer patients who develop psychological effects (such as anxiety, depression) over the course of active surveillance?
Are there any long term side effects associated with steroid cream treatments?
Are there any long-term carcinogenic risks associated with treatment with insulin analogues?
Are there any more reliable means of testing for prostate cancer?
Are there any non-drug alternatives to manage my asthma?
Are there any non-intrusive diagnostic tests that will identify aggressive prostate cancer patients whilst not identifying harmless cancers? (Tigers and Pussycats)
Are there any non-intrusive diagnostic tests that will identify aggressive prostate cancers whilst not identifying harmless cancers?
Are there any 'rapid relief' interventions for acute vertigo in Ménière's disease other than vestibular sedatives?
Are there any risks associated with depigmentation in treating vitiligo?
Are there any self-administered, cheap, easy and safe therapies that patients have discovered that help balance problems?
Are there any side effects associated with permanent, or semi-permanent, cosmetic camouflage for the management of vitiligo?
Are there any side effects associated with using calcineurin inhibitors (tacrolimus or pimecrolimus) to treat vitiligo?
Are there any side effects associated with using piperine (black pepper) cream to treat vitiligo?
Are there any side effects associated with using pseudocatalase cream combined with UVB light therapy in treating vitiligo?
Are there any side effects associated with using steroid creams in treating vitiligo?
Are there any side effects associated with using UVA light therapy in treating vitiligo?
Are there any side effects associated with UVB light therapy in treating vitiligo?
Are there any specific techniques that patients can adopt (e.g. certain visual or positional strategies) that can help in an acute attack of Ménière's disease?
Are there any treatments for prostate cancer that have minimal effect on urinary continence?
Are there any treatments to avoid esophageal stricture in patients with dystrophic epidermolysis bullosa?
Are there benefits of hospital treatment compared to home care treatment for psychotic episodes?
Are there differences between the mortality and complication rates found in people who use human analogue and animal insulins?
Are there differences in efficacy between the 3 phosphodiesterase inhibitors available in UK?
Are there different types of tinnitus and can they be explained by different mechanisms in the ear or brain?
Are there indicators of the correct time for starting individual treatments for prostate cancer?
Are there long term adverse effects of ECT for schizo-affective disorders
Are there suitable long-term pharmacological interventions to be recommended postnatally for women who have been diagnosed with gestational diabetes to prevent the onset of type 2 diabetes?
Are there unintended consequences from encouraging people of South Asian origin to stop using smokeless tobacco (for example, do they experience more dental pain or start smoking more tobacco)?
Are there ways (complementary or conventional) to alleviate the side effects of hormone therapy taken for prostate cancer?
Are topical tacrolimus and pimecrolimus for atopic eczema safe or can they cause lymphoma or skin cancer?
Are vaginal cones an effective therapy for women with post natal stress urinary incontinence?
Are variations in practice by non-specialist clinicians detrimental to outcomes for treatment of prostate cancer?
Are Vitamin D analogues (calcipotriol and tacalcitol) more effective in treating vitiligo when combined with light therapy?
Are Vitamin D analogues (calcipotriol and tacalcitol) more effective in treating vitiligo when combined with steroid creams?
Are weighted vaginal cones effective for urinary incontinence?
Aripiprazole for autism spectrum disorders (ASD)
Aripiprazole for people with schizophrenia whose illness has been partially responsive to clozapine
Aripiprazole versus other atypical antipsychotics for schizophrenia
Aripiprazole versus placebo for schizophrenia
Aromatase inhibitors for subfertile women with polycystic ovary syndrome
Aromatherapy and massage for symptom relief in patients with cancer
Aromatherapy for pain management in labour
Aromatherapy for treatment of postoperative nausea and vomiting
Aromatherapy massage for whiplash neck injury?
Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria
Arteriovenous extracorporeal membrane carbon dioxide removal
Artesunate for Lyme disease
Artesunate versus quinine for treating severe malaria
Arthroplasties (with or without bone cement) for proximal femoral fractures in adults
Arthroplasty versus fusion in single-level cervical degenerative disc disease
Arthroscopic debridement from knee osteoarthritis
Arthroscopy for temporomandibular disorders
Artichoke leaf extract for treating hypercholesterolaemia
'As required' medication regimens for seriously mentally ill people in hospital
As required versus fixed schedule analgesic administration schedules for treating postoperative pain in children and adults
Asenapine versus typical antipsychotics for schizophrenia
Aspiration and sclerotherapy versus hydrocoelectomy for treating hydrocoeles
Aspiration for treating radial head fractures
Aspiration of middle-ear effusions prior to insertion of ventilation tubes
Aspirin as adjunctive treatment for giant cell arteritis
Aspirin compared to other triptans and NSAIDS and acute migraine
Aspirin for in vitro fertilisation
Aspirin for vascular dementia
Aspirin versus low molecular weight heparin as thromboprophylaxis in surgical, particularly orthopaedic, patients.
Aspirin with or without an antiemetic for acute migraine headaches in adults
Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease
Assertive community treatment for people with severe mental disorders in the UK
Assertive Outreach Teams (AOT) for schizophrenia and other serious mental disorders in the UK
Assessment of techniques to ascertain correct endotracheal tube placement in neonates
Assessment of the value of neuropathic pain medication for treatment of chronic pelvic pain in women
Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)
Assistive technology for rheumatoid arthritis
At what age should preventative use of statins be started in those with Type 1 diabetes?
At what point following start of statins and other Coronary Vascular Disease risk-modification is it appropriate to reduce/withhold blood pressure lowering agents?
At-home versus institutional long-term-care for chronic functionally dependent older people
Attachment-based family therapy in young people to prevent suicide and suicidal behaviours
Atypical antipsychotics for disruptive behaviour disorders in children and youths
Audit and feedback: effects on professional practice and healthcare outcomes
Auditory integration training and other sound therapies for autism spectrum disorders
Auditory-verbal therapy for promoting spoken language development in children with permanent hearing impairments
Augmentation of antipsychotic monotherapy with lithium where a schizophrenic illness has shown only a partial response
Augmentation of antipsychotic monotherapy with sodium valproate where a schizophrenic illness has shown only a partial response
Augmentation of clozapine monotherapy with an appropriate second antipsychotic where a refractory schizophrenic illness has shown only a partial response to clozapine
Augmentative communication devices for adults with autism
Augmenting antipsychotic monotherapy with an antidepressant to treat persistent negative symptoms
Autoinflation for hearing loss associated with otitis media with effusion
Autologous blood donation to decrease blood loss and blood transfusion requirements for liver resection
Autologous hematopoietic stem cell transplantation following high-dose chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas
Autologous platelet-rich plasma for treating chronic wounds
Ayurvedic medicine for schizophrenia
Ayurvedic treatments for diabetes mellitus
Azathioprine (low dose) plus PUVA for repigmentation in vitiligo
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease
Azathioprine for psoriasis
Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease
Azathioprine or 6-mercaptopurine for induction of remission in fistulizing Crohn's disease
Azathioprine or 6-mercaptopurine to induce mucosal healing in Crohn's disease
Azathioprine to glucocorticosteroid treatment for patients with intestinal Crohn's disease compared with glucocorticosteroid treatment alone
Azelaic acid for acne
Azithromycin for treating uncomplicated malaria
Azithromycin versus penicillin G benzathine for early syphilis
B12 for pernicious anaemia dosing frequencies based on the patients’ symptoms rather than on number value of serum B12 blood tests
Baclofen for alcohol withdrawal
Balloon kyphoplasty for vertebral compression fractures
Balneotherapy for osteoarthritis
Balneotherapy for psoriasis
Balneotherapy for psoriatic arthritis
Balneotherapy for rheumatoid arthritis
Balsalazide versus mesalazine for maintenance of remission in ulcerative colitis
Balsalazide versus sulfasalazine for induction and maintenance of remission in ulcerative colitis
Banding ligation versus beta-blockers for primary prevention in oesophageal varices in adults
Barbiturates for acute traumatic brain injury
Bare-metal stenting compared with balloon angioplasty in patients with acute myocardial infarction
Bariatric surgery for non-alcoholic steatohepatitis in obese patients
Bariatric surgery for obesity
Bariatric surgery in the treatment of severely obese adolescents?
Barriers and facilitators to the implementation of doctor-nurse substitution strategies in primary care: qualitative evidence synthesis
Barriers and facilitators to the implementation of lay health worker programmes to improve access to maternal and child health: qualitative evidence synthesis
Bath emollients for atopic eczema
Bed rest in hospital for suspected impaired fetal growth
Bee venom acupuncture for rheumatoid arthritis
Behavioral interventions for improving contraceptive use among women living with HIV
Behavioral interventions for improving contraceptive use among women living with HIV
Behavioral interventions for urinanry incontinence in acute care settings
Behavioral interventions to promote condom use among women living with HIV
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in high-income countries
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in low- and middle-income countries
Behavioural and cognitive interventions with or without other treatments for the management of faecal incontinence in children
Behavioural and cognitive-behavioural group-based parenting programmes for early-onset conduct problems in children aged 3 to 12 years
Behavioural counselling to reduce incidences of skin cancer
Behavioural interventions as adjuncts to pharmacotherapy for smoking cessation
Behavioural interventions for attention deficit-hyperactivity disorder (ADHD)
Behavioural interventions for promoting respiratory protection use in workers
Behavioural treatments for non-epileptic attack disorder
Bendamustine for patients with indolent B cell lymphoid malignancies including chronic lymphocytic leukaemia
Benefit, tolerability, and safety of drugs used to treat urinary incontinenece in frail older people
Benefits and harms of biliary stenting via ERCP for pancreatico-biliary stricture confirmed or suspected to be malignant, prior to surgery?
Benzodiazapines for catatonia in persons with schizophrenia and other serious mental illnesses.
Benzodiazepines and antipsychotic drugs for urgent urgent sedation/control of acute behavioural disturbance
Benzodiazepines for generalised anxiety disorder (GAD)
Benzodiazepines for neuroleptic-induced tardive dyskinesia
Benzodiazepines for psychosis-induced aggression or agitation
Benzodiazepines for schizophrenia
Benzodiazepines in non-alcohol related delirium in hospitalised patients
Best psychological treatment for effective treatment of functional non-epileptic attacks
Beta radiation for glaucoma surgery
Beta radiation for glaucoma surgery
Beta2-adrenoceptor agonists for dysmenorrhoea
Beta2-receptor polymorphism for improving long-term beta-agonist efficacy in asthma
Beta2-receptor polymorphism for improving long-term beta-agonist efficacy in asthma
Beta-blockers for congestive heart failure in children
Beta-blockers for hypertension
Beta-blockers for slowing/halting the progress of aortic root dilation
Beta-blockers for slowing/halting the progress of aortic root dilation in people with Marfans syndrome
Betahistine for Ménière's disease or syndrome
Betamimetics for suspected impaired fetal growth
Bevacizumab (safety and efficacy) in the treatment of age-related macular degeneration
Bevacizumab for peole who have previously been treated with a taxane for metastatic breast cancer
Bezafibrate for primary biliary cirrhosis
Bicarbonate versus lactate solutions for acute peritoneal dialysis
Bicyclol for chronic hepatitis B
Bicyclol for chronic hepatitis C
Bile acid sequestrants among people with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection
Bile acids for non-alcoholic fatty liver disease and/or steatohepatitis
Biochemical tests of placental function for assessment in pregnancy
Biofeedback and/or sphincter exercises for the treatment of faecal incontinence in adults
Biofeedback for Ménière's disease.
Biofeedback for stress urinary incontinence
Bioidentical hormones for women with hot flushes
Biologics for juvenile idiopathic arthritis
Biologics for rheumatoid arthritis
Biomarkers as point-of-care tests to guide prescription of antibiotics in patients with acute respiratory infections in primary care
Biomarkers in stable coronary artery disease for prognosis
Biomedical risk assessment as an aid for smoking cessation
Biopsy versus resection for high grade glioma
Biopsy versus resection for the management of low-grade gliomas
Bismuth subsalicylate for lymphocytic colitis or collagenous colitis
Bisphosphonate therapy for children and adolescents with secondary osteoporosis
Bisphosphonates and atrial fibrillation
Bisphosphonates and other bone agents for breast cancer
Bisphosphonates for osteoporosis in people with cystic fibrosis
Bisphosphonates for osteoporosis in primary biliary cirrhosis
Bisphosphonates for osteoporotic fractures
Bisphosphonates in multiple myeloma: a network meta-analysis
Black cohosh (Cimicifuga spp.) for menopausal symptoms
Black pepper extract or piperine for repigmentation in vitiligo
Bladder retraining protocols for treating urinary incontinence
Bladder training in the management of overactive bladder symptoms
Bladder training in the management of urinary incontinence
Blood pressure lowering efficacy of alpha blockers for primary hypertension
Blood pressure lowering efficacy of loop diuretics for primary hypertension
Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension
Blood pressure targets for the treatment of patients with hypertension and cardiovascular disease
Blood transfusions for anaemia in patients with advanced cancer
Body positioning for spontaneously breathing preterm infants with apnoea
Bone anchored hearing aids for patients with congenital unilateral aural atresia
Bone augmentation procedures in implant dentistry
Bone marrow versus peripheral blood allogeneic hematopoietic stem cell transplantation for haematological malignancies
Botulinium toxin A in the treatment of idiopathic detrusor overactivity
Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy
Botulinum toxin compared with (a) usual care, (b) antimuscarinics and (c) augmentation cystoplasty in people with primary cerebral conditions with lower urinary tract dysfunction?
Botulinum toxin compared with antimuscarinics in people with primary cerebral conditions with lower urinary tract dysfunction?
Botulinum toxin compared with augmentation cystoplasty in people with primary cerebral conditions with lower urinary tract dysfunction
Botulinum toxin for myofascial pain syndromes in adults
Botulinum toxin for shoulder pain
Botulinum toxin for spasmodic dysphonia
Botulinum toxin for subacute/chronic neck pain
Botulinum toxin for the treatment of strabismus
Botulinum toxin for upper oesophageal sphincter dysfunction in neurological swallowing disorders
Botulinum toxin injections for adults with overactive bladder symptoms
Botulinum toxin injections for adults with overactive bladder syndrome
Botulinum toxin type A in the treatment of lower limb spasticity in cerebral palsy
Breast cancer in female survivors of childhood, adolescent or young adult cancer after radiotherapy involving the chest for their primary malignancy
Breast feeding and development of childhood wheeze
Breastfeeding for oral health in preschool children
Breastfeeding or breast milk for procedural pain in neonates
Breathing exercises for chronic obstructive pulmonary disease
Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children
Brief co-incubation of sperm and oocytes for in vitro fertilization techniques
Brief interventions (including brief advice) delivered by community members compared to brief interventions delivered by health professionals vs smokeless tobacco
Brief interventions for heavy alcohol users admitted to general hospital wards
Bright light therapy for patients at risk of delirium
Broad band UVB monotherapy for repigmentation in vitiligo
Broad-spectrum light sources for acne
Bromocriptine for type 2 diabetes mellitus
Bromperidol decanoate (depot) for schizophrenia
Bronchial thermoplasty for moderate or severe persistent asthma in adults
Bronchodilators for the prevention and treatment of chronic lung disease in preterm infants
Buccal or sublingual misoprostol for cervical ripening and induction of labour
Budesonide for lymphocytic colitis
Buflomedil for intermittent claudication
Built environment interventions for increasing physical activity in adults and children
Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome
Bupropion for depression
Cabergoline for preventing ovarian hyperstimulation syndrome
Caesarean delivery for the second twin
Caesarean section for non-medical reasons at term
Caesarean section versus vaginal delivery for preterm birth in singletons
Caesarean section versus vaginal delivery for preventing mother to infant hepatitis C virus transmission
Caffeine as an analgesic adjuvant for acute pain in adults
Caffeine reduction for urinanry incontinence in frail elderly people
Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients
Calcineurin inhibitor minimisation versus continuation of calcineurin inhibitor treatment for liver transplant recipients
Calcipotriol plus PUVA or UVB for psoriasis
Calcitonin for metastatic bone pain
Calcitonin testing for detection of medullary thyroid cancer in patients with thyroid nodules
Calcitriol and alfacalcidol for preventing fractures and falls
Calcium antagonists as an add-on therapy for drug-resistant epilepsy
Calcium antagonists for Duchenne muscular dystrophy
Calcium channel blockers for pulmonary arterial hypertension
Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Calcium supplementation for hip fracture
Calcium supplementation for prevention of primary hypertension
Can a change in anti-epileptic drug timing affect seizure control?
Can a large anti-epileptic drug dosage lead to an increase in seizure frequency in some individuals?
Can a non-pharmaceutical treatment be the primary one for psychosis?
Can acute deterioration of asthma be prevented? i.e. appropriate treatment 48 hours earlier; role of “At Risk” registers
Can angiotensin-converting enzyme (ACE) inhibitors and ACE angiotensin II receptor blockers (ARB) be used in combination to treat early diabetic nephropathy?
Can antibiotics be stopped after 6 or 12 weeks, and therapy continued with a non-antibiotic-based regimen such as benzoyl peroxide or a topical retinoid?
Can anti-epileptic drugs interfere with blood results?
Can antiviral therapy induce remission of proteinuria in paediatric patients?
Can any treatment avoid hair loss in patients with dystrophic epidermolysis bullosa?
Can applying steroids to my skin make eczema worse?
Can asthma medication at bedtime keep my child awake?
Can auditory 'brain training' improve tinnitus?
Can avoiding chocolate influence acne severity?
Can babies experience anti-epileptic drug withdrawal?
Can botulinum toxin injections be effective in treating nocturia?
Can bulking agents for stress urinary incontinence worsen urge incontinence?
Can children newly diagnosed with type 1 diabetes be stabilised at home or do all need hospital admission?
Can diet influence clinical outcomes in dystrophic epidermolysis bullosa patients?
Can EBV monitoring, such as measuring viral loads and responses such as cytotoxic T-cell counts, be effective in patients with Post Transplant Lymphoproliferative Disorders?
Can effective treatment of irritable bowel syndrome reduce lower urinary tract symptoms associated with prostate disease?
Can epilepsy treatment cause Dupuytren's?
Can exercise therapy improve outcomes for prostate cancer?
Can genetic testing for prostate cancer reduce my risk of being wrongly diagnosed, and over- or under-treated?
Can guidance or training for general practitioners on appropriate pathways of care improve the management of patients with urinary incontinence?
Can house dust mites worsen atopic eczema?
Can I have a nebuliser at home?
Can I rely on the PSA test alone to monitor prostate cancer recurrence after radical treatment?
Can IV aminophylline be used preventatively for people with difficult to treat asthma?
Can long term use of steroids for asthma cause problems with your liver?
Can modified diet influence acne severity?
Can my asthmatic child participate in sport at school?
Can needle biopsy of the prostate cause cancer to spread?
Can non-pharmaceutical treatment be used as a primary intervention in psychosis?
Can overdose/misuse of antipsychotic drugs cause psychotic symptoms?
Can overuse of salbutamol whilst taking becotide make one's asthma worse?
Can patients have a nebuliser at home to treat their asthma?
Can pelvic floor muscle training be effective in preventing incontinence associated with an overactive bladder?
Can people with schizophrenia be diagnosed earlier by GPs, and can the management of first episode psychosis be carried out in general practice?
Can pre-hospital clinicians perform Femoral Nerve Block safely and effectively in those with proximal femoral fracture?
Can pre-hospital clinicians perform urinary catheterisation safely and effectively in patients with proximal femoral fracture?
Can prostate cancer spread after transurethral resection of the prostate (TURP) procedure?
Can some individuals benefit from lower antiepileptic drug dosages than the therapeutic range suggested?
Can squamous cell cancer of the skin in an ageing UK population be reduced using currently available cream treatment for actinic keratoses?
Can stem cells be used to improve cleft palate repair (both primary and secondary)?
Can telemedicine be used to raise the use of blood glucose monitoring in adolescent and young people with diabetes, in particular?
Can the prostatectomy procedure cause prostate cancer cells to spread?
Can the way of measuring psoriasis and psoriatic arthritis in adults be improved?
Can too high a dose of antipsychotic cause psychotic symptoms?
Can treatments that I put on my skin make my eczema worse?
Can we manage acne without resorting to antibiotics and help to curb the rise of antibiotic resistance?
Canaloplasty for primary open-angle glaucoma
Cancer genetic risk assessment for individuals at risk of familial breast cancer
Cancer genetic risk assessment for individuals at risk of familial breast cancer
Canine scent detection methods for early diagnosis of human cancers
Cannabinoid type 1 receptor antagonists for smoking cessation
Cannabinoids for epilepsy
Cannabinoids for Tourette's Syndrome
Capsaicin for allergic rhinitis in adults
Carbamazepine for schizophrenia
Carbamazepine versus valproate monotherapy for epilepsy
Carbetocin for preventing postpartum haemorrhage
Carbetocin for preventing postpartum haemorrhage
Carbohydrate or fat-restricted diets for obesity
Carbohydrates for improving the cognitive performance of independent-living older adults with normal cognition or mild cognitive impairment
Cardiac resynchronisation therapy (CRT) in patients with atrial fibrillation compared with those with sinus rhythm
Cardiac resynchronisation therapy (CRT) versus optimal medical therapy in chronic heart failure patients with symptoms refractory to optimal medical therapy
Cardiac resynchronisation therapy with with implantable defibrilator (CRT-D) versus implantable cardioverter defibrilator (ICD) to reduce all-cause mortality in chronic heart failure patients
Cardiac resynchronization therapy for dilated cardiomyopathy
Cardiac testing for coronary artery disease in potential kidney transplant recipients
Cardiopulmonary interventions to decrease blood loss and blood transfusion requirements for liver resection
Cardiotocography versus intermittent auscultation of fetal heart on admission to labour ward for assessment of fetal wellbeing
Care delivery and self management strategies to improve outcomes for people with epilepsy
Care delivery and self-management strategies for children with epilepsy
Caries-preventive effect of glass ionomer and resin-based fissure sealants on permanent teeth
Carnitine for fatigue in multiple sclerosis
Carnitine supplementation for inborn errors of metabolism
Carnitine supplementation for preterm infants with recurrent apnoea
Carotid endarterectomy or carotid artery stenting to prevent stroke
Catheter ablation for paroxysmal and persistent atrial fibrillation
catheter ablation procedures in south-western europe
Catheter impregnation, coating or bonding for reducing central venous catheter related infections in adults
Catheter policies for management of long term voiding problems in adults with neurogenic bladder disorders
CBT for generalised anxiety disorder in older people compared to working age adults
Celecoxib for osteoarthritis
Celiac plexus block for pancreatic cancer pain in adults
Cemented, cementless or hybrid fixation options in total knee arthroplasty for osteoarthritis and other non-traumatic diseases
Central venous access sites for the prevention of venous thrombosis, stenosis and infection
Centralisation of services for gynaecological cancer
Cephalic version by moxibustion for breech presentation
Cephalic version by postural management for breech presentation
Cerebrolysin for vascular dementia
Cerebrospinal fluid drainage for thoracic and thoracoabdominal aortic aneurysm surgery
Certolizumab pegol (CDP870) for rheumatoid arthritis in adults
Certolizumab pegol for Crohn's disease
Cervical assessment by ultrasound for preventing preterm delivery
Cervical cap versus diaphragm for contraception
Cervical pessary for preventing preterm birth
Cervical ripening before first trimester surgical evacuation for non-viable pregnancy
Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy
Cesarean delivery for the prevention of anal incontinence in average risk pregnancies
Cetuximab in combination with radiotherapy compared with chemoradiotherapy in patients with head and neck cancer
Cetuximab in combination with radiotherapy compared with radiotherapy alone in patients with head and neck cancer
Chemical pleurodesis versus surgical intervention for persistent and recurrent pneumothoraces in cystic fibrosis
Chemoembolisation combined with liver resection for neuroendocrine tumours in patients with resectable liver metastases
Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma
Chemoradiation versus hyperthermia versus chemoradiation plus hyperthermia for locally advanced rectal cancer
Chemoradiotherapy for pancreatic carcinoma in patients with no disease progression following 3-4 months of induction chemotherapy
Chemotherapy alone versus chemotherapy plus radiotherapy for early stage Hodgkin lymphoma
Chemotherapy and surgery versus surgery alone in non-small cell lung cancer
Chemotherapy and/or radiotherapy in combination with surgery for ovarian carcinosarcoma
Chemotherapy for advanced, recurrent or metastatic endometrial carcinoma
Chemotherapy for brain metastases from small cell lung cancer
Chemotherapy for malignant germ cell ovarian cancer in adult patients with early stage, advanced and recurrent disease
Chemotherapy for metastatic and recurrent cervical cancer
Chemotherapy for metastatic carcinoma of the esophagus and gastro-esophageal junction
Chemotherapy for non-small cell lung cancer in the elderly population
Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia
Chemotherapy given before or after the radiotherapy in locally advanced nasopharyngeal carcinoma
Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer
Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer
Chemotherapy versus surgery with or without adjuvant chemotherapy and radiotherapy for localised primary gastric diffuse large B-cell lymphoma
Chemotherapy wafers for high grade glioma
Chemotherapy with cetuximab versus chemotherapy alone for chemotherapy-naive advanced non-small cell lung cancer
Chest compression alone versus chest compression plus artificial ventilation for out-of-hospital cardiac arrest
Chest physiotherapy for pneumonia in adults
Chest physiotherapy for pneumonia in children
Chinese and Indian herbal medications for repigmentation in vitiligo
Chinese Herbal Medicine (CHM) in the treatment of women with endometriosis
Chinese Herbal Medicine (CHM) in the treatment of women with primary dysmenorrhoea
Chinese herbal medicine for advanced pancreatic cancer
Chinese herbal medicine for atopic eczema
Chinese herbal medicine for endometriosis
Chinese herbal medicine for subfertile women with polycystic ovarian syndrome
Chinese herbal medicine for treating recurrent urinary tract infections in women
Chinese herbal medicines combined with other routine treatment for hyperthyroidism
Chinese herbal medicines for adverse events of transarterial chemoembolization in patients with primary liver cancer
Chinese herbal medicines for benign thyroid nodules in adults
Chinese herbal medicines for hypercholesterolemia
Chinese herbal medicines for induction of remission in advanced or late gastric cancer
Chinese herbal medicines for induction of remission in advanced or late gastric cancer
Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose and the delay of diabetes onset
Chinese herbal medicines for threatened miscarriage
Chinese herbs combined with Western medicine for severe acute respiratory syndrome (SARS)
Chinese medicinal herbs for acute bronchitis
Chinese medicinal herbs for alleviating chemotherapy-induced short term side effects in breast cancer patients
Chinese medicinal herbs for influenza
Chinese medicinal herbs for mumps
Chinese medicinal herbs for sore throat
Chinese zengse pill for repigmentation in vitiligo
Chiropractic medicine for Ménière's disease
Chlorambucil for patients with primary biliary cirrhosis
Chlorhexidine versus topical fluoride treatment for the prevention and management of dental caries in children and adolescents
Cholesterol-reducing agents for aneurysmal subarachnoid haemorrhage
Cholestyramine for lymphocytic colitis or collagenous colitis
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Cholinesterase inhibitors for mild cognitive impairment
Chorioretinal venous anastomosis for central retinal vein occlusion
Chromium picolinate supplementation for overweight or obese people
Chronic heart failure (CHF) self-management for patients with severe physical and mental co-morbidities
Ciclesonide for chronic asthma in adults and children
Ciclesonide versus other inhaled corticosteroids for chronic asthma in children
Ciclosporin for eczema
Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease
Cinnamon for diabetes mellitus
Citalopram versus other anti-depressive agents for depression
Citrate salts for preventing and treating kidney stones
Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology
Clinical and cost effectiveness of chemical sympathectomy in comparison with other methods of pain control for managing critical limb ischaemic pain
clinical and cost effectiveness of intrapartum antibiotic prophylaxis targeting group B streptococcus and guided by routine antenatal screening?
Clinical and cost effectiveness of selective stent placement compared with angioplasty plus primary stent placement for treating people with critical limb ischaemia caused by disease of the infra-geniculate arteries
Clinical and cost effectiveness of supervised exercise programmes compared with unsupervised exercise for treating people with intermittent claudication
Clinical and cost effectiveness of using GP practice lists to identify people at high risk of fracture, leading to formal risk assessment and possible treatment
Clinical and cost-effectiveness of depot and similar preparations of both conventional and atypical
antipsychotics for schizophrenia
Clinical- and cost-effectiveness of mid-urethral tape procedures in the first-line treatment of stress urinary incontinence.
Clinical and cost-effectiveness of monitoring the physical health of people with schizophrenia
Clinical and cost-effectiveness of pelvic floor muscle training in the first-line treatment of stress urinary incontinence
Clinical and economic benefits of cryotherapy compared to standard therapies for the primary treatment of localised prostate cancer
Clinical assessment to screen for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
Clinical course of action when a patient undergoing treatment for Lyme disease experiences a second tick bite
Clinical effectiveness, cost effectiveness and safety of DPP-4 inhibitors, compared with current UK practice or other newer agents, for the long-term management of blood glucose control in people with type 2 diabetes
Clinical effectiveness, cost effectiveness and safety of GLP-1 mimetics (with or without insulin), compared with standard UK practice or other newer agents, for the long-term management of blood glucose control in people with type 2 diabetes
Clinical efficacy and acceptability of combined antipsychotics (including clozapine) for schizophrenia when monotherapy has proved unsatisfactory
Clinical heart failure in children, adolescents and young adults treated with anthracyclines and/or irradiation involving the heart region
Clinical service organisation for heart failure
Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community-acquired pneumonia
Clinical, cost and occupational effectiveness of Supported Employment in the UK for schizophrenia
Clinical, economic, quality of life, self-esteem and occupational effectiveness of supported employment for people with schizophrenia
Clinical, social and economic outcomes, including quality of life and the methods and effects of risk monitoring, of treatment by acute day hospitals, assertive outreach teams, in-patient units, and crisis resolution and home treatment teams
Clinically-indicated replacement versus routine replacement of peripheral venous catheters
Clobazam versus other add-on treatments in the management of refractory epilepsy
Clofibrate in combination with phototherapy for unconjugated neonatal hyperbilirubinaemia
Clomiphene citrate in combination with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilization
Clonazepam for neuropathic pain and fibromyalgia in adults
Closed suction surgical wound drainage after hip fracture surgery
Closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a history of cryptogenic stroke or transient ischemic attack
Closure versus non–closure of the peritoneum at caesarean section
Clotiapine for schizophrenia
Clotiapine for schizophrenia
Clozapine against other atypicals for treatment-resistant schizophrenia
Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia.
Clozapine to reduce hostility, violence and suicide for people with schizophrenia
Coal tar plus phototherapy (including Goeckerman regime) for psoriasis
Co-bedding in neonatal nursery for promoting growth and neurodevelopment in stable preterm twins
Coblation versus other surgical procedures for tonsillectomy
Coenzyme Q10 for Parkinson's disease
Co-enzyme Q10 supplementation for the primary prevention of cardiovascular disease
Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS
Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia
Cognitive behaviour therapy versus specific pharmacological treatments for schizophrenia
Cognitive behaviour therapy versus standard care for schizophrenia
Cognitive behavioural therapies versus other psychological therapies for depression
Cognitive behavioural therapies versus treatment as usual for depression
Cognitive Behavioural Therapy (CBT) for people with chronic headache disorders to improve headache outcomes and quality of life
Cognitive Behavioural Therapy (CBT) for schizophrenia
Cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment resistant depression in primary care: a randomised controlled trial
Cognitive Behavioural Therapy for borderline personality disorder
Cognitive behavioural therapy for men who physically abuse their female partner
Cognitive behavioural therapy for migrainous vertigo
Cognitive behavioural therapy for the treatment of moderate and severe anxiety disorders in adults with autism
Cognitive Behavioural Therapy in the first episode of schizophrenia and those at risk of relapse
Cognitive reframing for carers of people with dementia
Cognitive rehabilitation (for domains other than memory and learning) in multiple sclerosis
Cognitive rehabilitation for executive dysfunction in adults with stroke or other adult non-progressive acquired brain damage
Cognitive rehabilitation in patients with aquired brain injury
Cognitive stimulation and acetylcholinesterase inhibitors for Alzheimer’s disease over six months
Cognitive stimulation or acetylcholinesterase inhibitors for Alzheimer’s disease over six months
Cognitive stimulation to improve cognitive functioning in people with dementia
Cognitive training for attention deficit-hyperactivity disorder (ADHD)
Cognitive-behavioural interventions for children who have been sexually abused
Cognitive-behavioural therapy (CBT) interventions for young people aged 10 to 18 who sexually offend
Colchicine for primary biliary cirrhosis
Cold-water immersion (cryotherapy) for preventing and treating muscle soreness after exercise
Colesevelam for type 2 diabetes mellitus
Collaboration between local health and local government agencies for health improvement
Collaborative care for depression and anxiety problems
Collaborative care for depression and anxiety problems in primary care
Colloid solutions for fluid resuscitation
Colloids versus crystalloids for fluid resuscitation in critically ill patients
Colony-stimulating factors for prevention and treatment of infectious complications in patients with acute myelogenous leukemia
Colorectal stents for the management of malignant colonic obstructions
Combinant therapy for seizure control in neonatal seizures
Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour
Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children
Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children
Combination inhaled corticosteroids and long-acting beta2-agonists for children and adults with bronchiectasis
Combination inhaled steroid and long-acting beta2-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease
Combination inhalers as single treatment for asthma compared to standard therapy
Combination injectable contraceptives for contraception
Combination pharmacological and weight-loss therapy for non-alcoholic fatty liver disease
Combination pharmacotherapy for the treatment of neuropathic pain in adults
Combination therapies in hepatitis B patients with decompensated cirrhosis
Combination therapy for pain management in inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis)
Combination therapy of heparin and graded compression stockings versus heparin alone for prevention of fatal pulmonary embolism in colorectal surgery
Combination therapy with newer nucleoside analogues for chronic hepatitis B
Combined corticosteroid and long-acting beta2-agonist in one inhaler versus long-acting beta2-agonists for chronic obstructive pulmonary disease
Combined corticosteroid and longacting bronchodilator in one inhaler for chronic asthma
Combined corticosteroid and longacting bronchodilator in one inhaler for chronic asthma
Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccine for primary prevention of hepatitis B
Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB)
Combined oral contraceptive pills for treatment of acne
Combined pharmacology and psychotherapy for older adults with Generalised Anxiety Disorder
Combined pharmacotherapy and behavioural interventions for smoking cessation
Combined spinal-epidural versus epidural analgesia in labour
Combined split-thickness/suction grafts for repigmentation in vitiligo
Combined treatment with macrolides and hydroxychloquine for Lyme disease
Combined vestibular rehabilitation and cognitive behavioural treatment of chronic dizziness
Combining antipsychotics to treat schizophrenia that has proved to be poorly responsive to adequate trials of antipsychotic monotherapy
Combining presciption antidepressant drugs and psychological treatments for depression
Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Commercially available pelvic binder/splint compared to a circumferential sheet for immobilising/stabilising a pelvic trauma in the prehospital environment
Communication aids for patients with central nervous system tumours
Communication skills training for healthcare professionals working with people who have cancer
Communication skills training for mental health professionals working with people with severe mental illness
Community based interventions for reducing dengue incidence
Community coalition-driven interventions to reduce health disparities among racial and ethnic minority populations
Community interventions for preventing smoking in young people
Community mental health teams (CMHTs) for people with severe mental illnesses and disordered personality
Community Mental Health Teams trained to deliver specialist treatment, compared to specialist teams (e.g. Crisis Resolution, Home Treatment, and Early Intervention), for serious mental illness
Community wide interventions for increasing physical activity
Community-based self-management programs for improving participation in life activities in older adults with chronic conditions
Community-based, population level interventions for promoting child oral health
Community-directed interventions for informing and/or educating about early childhood vaccination
Community-wide approaches to managing obesity
Comparable effectiveness of therapies for unresectable recurrent and in-transit extremity melanoma.
Comparative educational outcomes of different drug treatments for childhood attention deficit-hyperactivity disorder (ADHD)
Comparative effectiveness of different combined oral contraceptive pills for acne in women
Comparative efficacy of biological therapies for patients with psoriasis who fail to respond to conventional systemic treatments
Compared to a plaster on the buttock, is the therapeutic effect of an oestrogen plaster against menopausal symptoms on the stomach significantly higher?
Comparison of alternative therapies and progestagens and anti-progestagens for pain associated with endometriosis
Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants
Comparison of chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for patients with early unfavourable or advanced stage Hodgkin lymphoma
Comparison of different models of preconception counselling to reduce adverse pregnancy outcome in women with epilepsy
Comparison of initial antibiotic regimens for Lyme disease where both options are less than one month
Comparison of luminal agents for use in conjuction with nitroimidazoles for eradication of Entamoeba histolytica from the intestine and for decreasing relapse
Comparison of short and long term treatment regimens for amoebic colitis
Comparison of speech and language therapy techniques for speech problems in Parkinson's disease
Comparison of speech and language therapy techniques for speech problems in Parkinson's disease
Comparison of the efficacy of different anti-TNF agents in Crohn's disease
Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women
Comparisons of outcomes from different packages of care for treatment of chronic pelvic pain in women
Complementary and alternative medicine in the treatment of sinusitis
Complementary and alternative therapies for acne
Complementary and miscellaneous interventions for nocturnal enuresis in children
Complementary therapies for prostate cancer: is there any evidence of their efficacy/effectiveness?
Complementary therapies for schizophrenia
Complementary therapies for schizophrenia
Complementary therapies in the management of childhood nocturnal enuresis
Complete cytoreduction for advanced epithelial ovarian cancer
Complex behavioural interventions for nocturnal enuresis in children
Complex interventions for preventing diabetic foot ulceration
Compliance therapy for schizophrenia
Comprehensive exercise interventions for multiple sclerosis
Comprehensive geriatric assessment for older adults admitted to hospital
Compression for preventing recurrence of venous ulcers
Compression for venous leg ulcers
Compression stockings for the initial treatment of varicose veins in patients without venous ulceration
Compulsory community and involuntary outpatient treatment for people with severe mental disorders
Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death
Computed tomography versus magnetic resonance imaging versus bone scintigraphy for clinically suspected scaphoid fractures in patients with negative plain radiographs
Computer-assisted versus oral-and-written dietary history taking for diabetes mellitus
Computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of type 2 diabetes mellitus
Computer-assisted versus oral-and-written history taking for the management of cardiovascular disease
Computer-based diabetes self-management interventions for adults with type 2 diabetes mellitus
Computer-generated reminders delivered on paper to healthcare professionals; effects on professional practice and health care outcomes
Concomitant adalimumab and other immunosuppressants for induction and maintenance of remission in Crohn's disease
Concomitant corticosteroids and adalimumab for induction and maintenance of remission in Crohn's disease
Concurrent chemoradiotherapy (alternative fractionation schedules) versus sequential chemoradiotherapy
Conjugate vaccines for preventing Haemophilus influenzae type b infections in children under 5 years of age
Conservative compared to operative treatment for hip fractures in adults
Conservative interventions for treating diaphyseal fractures of the forearm bones in children
Conservative interventions for treating hyperextension injuries of the proximal interphalangeal joints of the fingers
Conservative management for postprostatectomy urinary incontinence
Conservative management of acoustic neuroma
Conservative management of nocturia in adults
Conservative management such as pelvic floor muscle training for postprostatectomy urinary incontinence
Conservative prevention and management of pelvic organ prolapse in women
Conservative treatment for middle third clavicle fractures in adolescents and adults
Conservative treatment for whiplash
Constraint-induced movement therapy of the upper limb in children with hemiplegic cerebral palsy
Consultation letters for medically unexplained physical symptoms in primary care
Consumer guidelines for chronic disease management
Consumer-providers of care for adult clients of statutory mental health services
Containment strategies for people with serious mental illness
Continence care in the frail elderly.
Continence education programmes
Contingency management for substance use disorders
Continuation and maintenance treatments for depression in older people
Continuation and maintenance treatments for depressive disorder in older adults
Continuous and interrupted suturing techniques for repair of episiotomy or second-degree tears
Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease
Continuous glucose monitoring systems for type 1 diabetes mellitus
Continuous heparin infusion to prevent thrombosis and catheter occlusion in neonates with peripherally placed percutaneous central venous catheters
Continuous passive motion for preventing venous thromboembolism after total knee arthroplasty
Continuous positive airway pressure (CPAP) for acute bronchiolitis in children
Continuous subcutaneous insulin infusion compared with intensive insulin injections
Continuous support for women during childbirth
Continuous support for women during childbirth.
Continuous versus bolus intragastric tube feeding for preterm and low birth weight infants with gastro-oesophageal reflux disease
Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections
Continuous versus intermittent renal replacement therapy for patients with acute kidney injury
Continuous versus interrupted skin sutures for non-obstetric surgery
Contralateral bone anchored hearing aids in acquired unilateral sensorineural hearing loss in adults
Contralateral prophylactic mastectomy for women with breast cancer
Control of humidity and excessive heat in the home for preventing or reducing the severity of atopic eczema
Conventional occlusion versus pharmacologic penalization for amblyopia
Cooling for cerebral protection during brain surgery
Cooling for newborns with hypoxic ischaemic encephalopathy
Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients
Cortical and deep brain stimulation for functional recovery and reducing complications after stroke
Corticosteroid implants for chronic non-infectious uveitis
Corticosteroid injection for de Quervain's tenosynovitis
Corticosteroid injections compared to splinting or surgery for trigger finger in adults
Corticosteroids as adjunctive therapy in the treatment of influenza
Corticosteroids as standalone or add-on treatment for sore throat
Corticosteroids for acute bacterial meningitis
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy
Corticosteroids for Guillain-Barr? syndrome
Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy
Corticosteroids for ocular toxoplasmosis
Corticosteroids for parasitic eosinophilic meningitis
Corticosteroids for pneumonia
Corticosteroids for preventing postherpetic neuralgia
Corticosteroids for the common cold
Corticosteroids for the treatment of chronic asthma in adults and children aged 12 years and over
Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis)
Corticosteroids for treating hypotension in preterm infants
Corticosteroids for treating nerve damage in leprosy
Corticosteroids for treating optic neuritis
Corticosteroids for treating optic neuritis
Corticosteroids for viral myocarditis
Corticosteroids used in addition to antiviral drugs in patients with Ramsay Hunt syndrome
Cost effectiveness of interventions to prevent or manage obesity in children and adults in the UK?
Cost effectiveness of lisdexamfetamine in children and adolescents with attention deficit-hyperactivity disorder (ADHD)
Cost-effectiveness analysis of mesalamine for prevention of post-operative recurrence of Crohn's disease
Cost-effectiveness of clobazam versus newer anti-epileptic drugs
Cost-effectiveness of the newest anti-epileptic drugs as first line therapy
Costs and benefits of preconception counselling of women with epilepsy to healthcare organisations
Costs and benefits of preconception counselling to women with epilepsy
Cot-nursing versus incubator care for preterm infants
Cotrimoxazole for the prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection
Could electronic/computerised equipment help standardise the interpretation of diagnostic tests such as the Digital Rectal Exam for men with prostate cancer?
Could the use of standard systems (e.g. nomograms) to assess prostate cancer risk and response to treatment improve outcomes?
Covered versus uncovered metal palliative biliary stents for obstructing pancreatic carcinoma
Cranberries for preventing urinary tract infections
Creatine and creatine analogues in hypertension and cardiovascular disease
Creatine for amyotrophic lateral sclerosis/motor neuron disease
Creatine for treating muscle disorders
Crisis intervention for people with severe mental illnesses
Crisis interventions for people with borderline personality disorder
Criteria for prophylactic treatment, and choice of antibiotic regimen, to prevent Lyme disease following a tick bite
Critical incident audit and feedback to improve perinatal and maternal mortality and morbidity
Cross-modal supplementation for tinnitus
Cryotherapy following total knee replacement
Cryotherapy for hepatocellular carcinoma
Curcumin for maintenance of remission in ulcerative colitis
Customised versus population-based growth charts as a screening tool for detecting small for gestational age infants in low-risk pregnant women
Custom-made foot orthoses for the treatment of foot pain
Cycling infrastructure for reducing cycling injuries in cyclists
Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis
Cyclo-oxygenase (COX) inhibitors for preventing preterm labour
Cyclophosphamide versus ifosfamide for paediatric and young adult bone and soft tissue sarcoma patients
Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in systemic lupus erythematosus
Cyclophosphamides for multifocal motor neuropathy
Cyclosporin A for primary biliary cirrhosis
Cyroablation versus radiofrequency catheter ablation for AV nodal re-entrant tachycardia
Daclizumab for relapsing remitting multiple sclerosis
Daclizumab for relapsing remitting multiple sclerosis
Daily oral iron supplementation during pregnancy
Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive mechanical ventilation
Damage control surgery for abdominal trauma
Danazol for pelvic pain associated with endometriosis
Dance movement therapy for depression
Dance/movement therapy for improving psychological and physical outcomes in cancer patients
Day centres for severe mental illness
Day hospital versus admission for acute psychiatric disorders
Debridement for surgical wounds
Decentralising HIV treatment delivery in middle- and low-income countries
Decision aids and the effect on choice for surgery and knowledge of treatment options for breast cancer patients
Decision support interventions for people making decisions about participation in clinical trials
Decompressive surgery for treating nerve damage in leprosy
Decompressive surgery for treating nerve damage in leprosy
Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock
Deferasirox for managing iron overload in people with thalassaemia
Deflation of gastric band balloon in pregnancy for improving outcomes
Deflation of gastric band balloon in pregnancy for improving outcomes
Dehydroepiandrosterone (DHEA) for systemic lupus erythematosus
Delayed antibiotics for respiratory infections
Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants
Delirium associated with commonly prescribed medicines
Delivery methods of education for people with type 2 diabetes.
Delivery of inhaled steroids in children - which is the most effective method of delivering drugs for asthmatic children?
Denosumab for the treatment and prevention of postmenopausal osteoporosis
Dental auxiliaries for dental care
Dental extractions prior to radiotherapy to the jaws for reducing post-radiotherapy dental complications
Dental surgery for patients on anticoagulant therapy with warfarin
Depigmentation for improved quality of life in severe vitiligo
Depot versus daily administration of gonadotrophin-releasing hormone agonist protocols for pituitary down regulation in assisted reproduction cycles
Depot/long-acting injectable antipsychotic preparations for schizophrenia
Dermofasciectomy for Dupuytren’s contractures of the hand
Desensitisation therapy (allergen-specific immunotherapy) for atopic eczema
Desmopressin acetate (DDAVP) for preventing and treating acute bleeds during pregnancy in women with congenital bleeding disorders
Desmopressin plus enuresis alarm for nocturnal enuresis
Desmopressin to decrease blood loss and blood transfusion requirements for liver resection
Deterioration in the home of a person with asthma — action by patient including when to call for GP, when to self-admit
Determine the long-term effects of prompted voiding on daytime urinary incontinence in nursing home residents and homebound frail older adults
Detoxification therapy for Lyme disease
Device modified trabeculectomy for glaucoma
Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin and school performance
Dextrose for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Diagnosis of gestational diabetes
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions
Dialyser reuse for people with end-stage kidney disease requiring haemodialysis
Diaries for recovery from critical illness
Diclofenac with or without an antiemetic for acute migraine headaches in adults
Diclofenac with or without an antiemetic for acute migraine headaches in adults
Diet and dietary supplements for schizophrenia
Diet and exercise interventions for preventing gestational diabetes mellitus
Dietary advice for reducing cardiovascular risk
Dietary and physical activity interventions on maternal weight in pregnant women for long term maternal and fetal outcomes
Dietary antioxidants and primary prevention of age related macular degeneration
Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Dietary flavonoid for preventing colorectal neoplasms
Dietary interventions during recovery from Lyme disease
Dietary interventions for lowering cholesterol in dialysis patients
Dietary interventions for mineral and bone disorder in people with chronic kidney disease
Dietary interventions for multiple sclerosis
Dietary interventions for rheumatoid arthritis
Dietary sodium manipulation and asthma
Dietary sodium modification on asthma control
Dietary supplements for chronic gout
Dietary supplements for established atopic eczema
Dietary supplements, herbal medicines, or other alternative medications for Lyme disease when taken in combination with conventional treatment,
Different antibiotic regimens for treating asymptomatic bacteriuria in pregnancy
Different antibiotic treatments for group A streptococcal pharyngitis
Different antibiotic treatments for group A streptococcal pharyngitis
Different antihypertensive strategies in patients with diabetes, nephropathy and a history of myocardial infarction for the treatment of hypertension and prevention of heart failure
Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease
Different intensities of glycaemic control for pregnant women with pre-existing diabetes
Different magnesium sulphate regimens for neuroprotection of the fetus for women at risk of preterm birth
Different methods of vascular occlusion for elective liver resection
Different referral patterns in primary care for the urinary incontinence patient
Different strategies for diagnosing gestational diabetes to improve maternal and infant health
Different strategies for using topical corticosteroids for established eczema
Different types of alarm in the managment of childhood nocurnal enuresis
Different types of dietary advice for women with gestational diabetes mellitus
Different types of intermittent pneumatic compression devices for preventing venous thromboembolism in patients after total hip replacement
Different types of practitioners and treatment response to acupuncture for migraine prophylaxis
Different unfractionated heparin doses for preventing arterial thrombosis in children undergoing cardiac catheterization
Differential effects of D-hormone analogs and native vitamin D on falls
Differing dose of normobaric and hyperbaric oxygen therapy combined with other therapies for migraine and cluster headache
Direct comparisons between atypical antipsychotics for schizophrenia
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of venous thromboembolism following total hip or knee replacement
Direct versus indirect bonding for bracket placement in orthodontic patients
Discharge planning from hospital to home
Disease management interventions for improving self-management in lower-limb peripheral arterial disease
Disease modifying anti-rheumatic drugs in people with cystic fibrosis-related arthritis
Disposable surgical face masks for preventing surgical wound infection in clean surgery
Dissection versus diathermy for tonsillectomy
Distal aortic perfusion during thoracoabdominal aneurysm repair for prevention of paraplegia
Disulfiram for alcohol use disorder
Dithranol plus PUVA for psoriasis
Diuretics for heart failure
Diuretics for Ménière's disease or syndrome
Diuretics for respiratory distress syndrome in preterm infants
DMARDs for rheumatoid arthritis
Do adults with psoriasis and psoriatic arthritis who use topical therapies who see non-medical healthcare professional have different outcomes on the Psoriasis Area and Severity Index (PASI) and service use?
Do alterations in diet help in asthma?
Do alternative / complementary treatments such as psychological techniques help in asthma?
Do antibiotics and antiseptics applied to the skin work in the treatment of eczema?
Do antipsychotic drugs cause permanent physical adverse effects?
Do antipsychotic drugs make learning difficult?
Do anti-TNFs increase the risk of lymphoma in rheumatoid arthritis patients?
Do automated/mechanical chest compression devices improve survival in adult out-of-hospital cardiac arrest?
Do bath additives work in the treatment of eczema?
Do bisphosphonates increase the risk of atrial fibrillation?
Do breathing exercises help in asthma?
Do breathing exercises help in asthma?
Do calcium channel blockers prevent acute tubular necrosis (ATN) in cadaveric kidney transplant recipients?
Do certain antiepileptic drugs affect thyroid function?
Do certain antiepileptic drugs lead to clustering of seizures?
Do cleansers reduce acne severity?
Do combination inhalers taken for asthma cause osteoporosis with long term use?
Do combined exercise and self-management programmes reduce pain and increase function in community-based patients with knee and hip osteoarthritis?
Do continuous insulin infusion pumps offer an advantage over traditional intermittent insulin injections in terms of pregnancy outcomes in women with type 1 diabetes?
Do corticosteroids for asthma in children cause excess weight gain?
Do Crisis or Outreach teams prevent relapse of psychosis?
Do delays in reporting prostate symptoms to GPs affect disease outcomes?
Do different insulin delivery systems allow me to make different lifestyle choices about diet and exercise
Do different propellants in inhalers for asthma predispose to migraine headaches?
Do epilepsy medications affect memory in the long term?
Do epilepsy medications affect the liver in the long term?
Do epilepsy medications cause impotence?
Do epilepsy medications cause shaking limbs?
Do fitness regimens have adverse effects on asthma?
Do foot orthotics have any structural or functional effect on hip and knee osteoarthritis?
Do herbal medicines prevent asthma attacks?
Do high plasma levels of trimethylamine (TMAO) gut flora metabolism of phosphatidylcholine cause cardiovascular disease?
Do homeopathic remedies help control asthma symptoms?
Do house dust mites cause atopic eczema?
Do I have to take asthma control treatment every day even when I am feeling fine?
Do I need to take my preventer inhaler for asthma every day?
Do I really need to use the asthma preventer every day?
Do individual metabolic differences influence outcomes treatment in schizophrenia? In what way?
Do individuals with erythromycin/clindamycin resistant propionibacterial floras respond adequately when erythromycin or clindamycin are used without concomitant benzoyl peroxide?
Do inhaled corticosteroids for asthma predispose one to diabetes?
Do inhaled steroids taken for asthama cause weight gain?
Do inhaled streroids for asthma cause lichen planus or lupus of the gums?
Do inhalers for asthma affect teeth?
Do interventions such as educating school staff help children with diabetes live a less restricted life during school time?
Do long acting insulin analogues maintain glucose control better than NPH insulin in the long term?
Do low dose oral antibiotics with good lipophilic properties lead to adequate clinical efficacy through anti-inflammatory rather than anti-microbial action and in turn reduce likelihood of resistance emerging?
Do medications that targets genes have better effects on prostate cancer treatment?
Do minor increases in heart rate and blood pressure caused by central nervous system stimulants in attention deficit hyperactivity disorder (ADHD) patients result in adverse cardiovascular effects
Do multi-dose insulin injection regimes adversely affect the quality of life of [i] children and adolescents and [ii] adults with Type 1 diabetes?
Do Omega 3 supplements alleviate psychotic symptoms?
Do patient/public and health professionals' views of urinary incontinence effect continence status?
Do patients who are withdrawing from olanzapine, taken for schizophrenia, experience withdrawal symptoms after more than 5 years of treatment?
Do patients with dystrophic epidermolysis bullosa who receive calcium and vitamin D supplements and/or bisphosphonates therapy have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive continuous dental care follow-up have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive continuous retinoid therapy have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive early gastrostomy have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive esophageal dilatations have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive nutritional supplements have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive periodic bone density monitorization have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive periodic cardiologic monitorization have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive periodic nephrologic monitorization have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive psychological interventions have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who use adapted shoes/adapted insole/double socks have better outcomes than those that do not?
Do patients with in-situ squamous cell carcinoma and dystrophic epidermolysis bullosa who receive photodynamic therapy have better outcomes than those that receive other modalities of treatment?
Do patients with recurrent squamous cell carcinoma and dystrophic epidermolysis bullosa who receive amputation have better outcomes than those that receive local excision?
Do patients with squamous cell carcinoma and dystrophic epidermolysis bullosa who receive the sentinel node biopsy have better outcomes than those that do not?
Do people who have a first seizure need to see an epilepsy specialist for treatment?
Do phosphodiesterase inhibitors help women with diabetes mellitus who have sexual dysfunction?
Do phosphodiesterase inhibitors improve erectile dysfunction in people with uncontrolled diabetes mellitus?
Do preventer inhalers with steroids have to be used every day for children with asthma?
Do preventer inhalers with steroids have to be used every day for children with asthma?
Do probiotics significantly reduce trimethylaminuria (TMAU1) producing bacteria in the human intestine and does this result in clinically relevant decreases in TMA production, and thus body odour, in patients with TMAU1?
Do psychological interventions improve arthritis pain management?
Do psychological therapies decrease dependence on standard medication and promote full recovery in severe mental illness?
Do psychological therapies decrease relapse and re-hospitalizations in patients with severe mental illness?
Do rituximab or abatacept for rheumatoid arthritis increase the risk of infection?
Do side effects to a certain anti-epileptic medication help predict side effects to other anti-epileptic medications?
Do some antiepileptic drugs cause auras?
Do spacers work as well as nebulisers in severe asthma attacks?
Do statins have a beneficial effect in preventing prostate cancer?
Do steroid inhalers taken for asthma cause osteoporosis?
Do steroids lose any effectiveness used over a long period of time for asthma?
Do steroids taken for asthma cause osteoporosis in later life?
Do the adverse effects of antipsychotic drugs outweigh the benefits?
Do the long acting insulin analogues improve diabetes complications better than NPH insulin in the long term?
Do the meglitinide analogues reduce the morbidity and mortality from diabetes associated complications?
Do the newer antiepileptic drugs cause low bone mineral density?
Do treatments other than medication help asthma symptoms?
Do uterine fibroids cause infertility and should they be removed to increase fertility?
Do variations in GP awareness of prostate cancer affect outcomes?
Do variations in GP awareness of prostate cancer affect outcomes?
Do you have different daily water requirements if you are taking epilepsy medication?
Does a combination of albuterol and Benadryl relieve distress in people who are thought to have food "intolerance's" and asthma?
Does a combination treatment of hormone therapy and chemotherapy for prostate cancer improve the disease outcome?
Does a digital rectal exam alone or in combination with other tests improve diagnosis of prostate cancer?
Does a high carbohydrate diet and the subsequent increased daily dose of insulin lead to more frequent and/or more severe hypoglycaemia in people with Type 1 diabetes?
Does a high carbohydrate diet cause weight increase in Type 1 and Type 2 diabetes
Does access to the latest diagnostic equipment improve outcomes for prostate cancer?
Does access to the latest treatment equipment improve outcomes for prostate cancer?
Does active pituitary monitoring post traumatic brain injury for children improve outcomes?
Does active surveillance work for treatment of prostate cancer?
Does active surveillance work for treatment of prostate cancer?
Does activity scheduling and physical exercise increase well being of patients with schizophrenia?
Does acupuncture help in asthma?
Does acupuncture produce analgesia and is any or all of this a placebo effect?
Does acupuncture reduce the need for inhaled steroids in asthma?
Does Advair Diskus 500/50 taken for asthma cause musculoskeletal pain?
Does advice to parents for children with asthma on allergen avoidance help avoid asthma attacks?
Does allergen avoidance work in asthma?
Does anti-cyclic citrullinated peptide guide the management of patients with early rheumatoid arthritis?
Does assessing risk factors affect my risk of being wrongly diagnosed with prostate cancer , and over- or under-treated?
Does avoidance of contact with animals reduce asthma severity?
Does avoidance of peanuts in early life reduce the risk of peanut allergy?
Does avoiding certain foods help to control asthma in children?
Does avoiding triggers help my asthma?
Does belonging to a religious movement help my schizophrenia?
Does Benfotiamine (form of Vit B1) prevent diabetes complications?
Does breastfeeding protect against allergic rhinitis during childhood?
Does breathing air through a salt pipe help to control asthma symptoms?
Does change of environment for a person affect the prevalence of asthma?
Does changing geographical locations to a warmer climate help with asthma?
Does complementary therapy help with quality of life in patients on active surveillance for prostate cancer?
Does consuming alcohol affect my risk of developing prostate cancer?
Does continuous glucose monitoring in diabetes yield better self-management?
Does delayed diagnosis and thus treatment of pernicious anaemia cause people to develop adverse effects such as peripheral neuropathy or sub-acute combined degeneration of the spinal cord?
Does early aggressive treatment at the first signs of acne alter the natural history of disease and reduce the need for further systemic therapy?
Does early detection of prostate cancer give more effective treatment options?
Does EBRT (external beam radiotherapy) for prostate cancer cause bone necrosis?
Does ECT for depression cause memory loss?
Does ECT for schizophrenai cause memory loss?
Does effective intranasal corticosteroid treatment of rhinitis reduce asthma exacerbations and costs?
Does excessive coffee drinking affect prostate cancer risk?
Does family therapy for schizophrenia reduce relapse?
Does general or regional anaesthetic cause post-operative cognitive decline?
Does having a stoma (in a patient with Crohn's disease) cause drowsiness?
Does having had a vasectomy increase my risk of prostate cancer?
Does having to pay for asthma prescriptions reduce the effectiveness of treatment in controlling asthma?
Does home oxygen benefit people with chronic heart failure?
Does homeopathy help in asthma?
Does hyperventilating help reduce asthma symptoms?
Does identification of microalbuminuria during pregnancy offer the opportunity for appropriate pharmacological treatment to prevent progression to pre-eclampsia in women with pre-existing diabetes?
Does incresing patient education awareness of new technological developments improve outcomes for patients with diabetes?
Does investigation of possible allergies improve the treatment of asthma?
Does involvement of parents in the care plan improve the care of children with diabetes?
Does long term use of steroids for asthma increase the risk of arteriosclerosis?
Does long-term low-dose trimethoprim promote wound healing in patients with severe forms of epidermolysis bullosa and how well is low dose trimethoprim tolerated?
Does memantine reduce progression of functional disability in people with severe vascular dementia?
Does methotrexate monotherapy increase the risk of malignancy in rheumatoid arthritis?
Does mild renal impairment get worse if a person takes lithium for mood disorders?
Does moving to a sunnier climate help asthma?
Does my risk of prostate cancer depend on how sexually active I am, or have been?
Does not having to pay for prescription medication for chronic asthma help improve symptoms?
Does not paying for medication for asthma increase compliance?
Does patient information on drugs used to treat prostate cancer have any effect on outcomes?
Does poly-pharmacy in older patients with severe mental illness cause greater adverse events?
Does prehospital ultrasound improve survival of the trauma patient?
Does primary chemo-irradiation improve loco-regional control and overall survival? squamous cell carcinoma of the Head & Neck and for which specific anatomical sites?
Does psychodynamic therapy really make a difference to symptoms, functioning and quality of life of people with schizophrenia?
Does reducing glucose variability reduce long term complications of type 1 diabetes even when average levels are not reduced?
Does regular use of emollients reduce disease relapse in atopic eczema?
Does removal of pets influence disease activity in established atopic eczema?
Does risperidone worsen psoriasis?
Does routine oxygen supplementation in patients with acute stroke improve outcome?
Does routine review of people with asthma improve outcome?
Does salbutamol used to treat asthma cause cramps?
Does self-management education for children with epilepsy change seizure frequency?
Does Seretide affect pregnancy?
Does serial PSA measurement in patients with prostate cancer accurately monitor disease progression?
Does serial PSA measurement in patients with prostate cancer accurately monitor disease progression?
Does setting national targets for blood glucose levels discourage health professionals setting targets according to individual needs/situations?
Does sleep or the lack of sleep affect the way your epilepsy medication works
Does social support in the early acute phase of schizophrenia help reduce relapse?
Does staff training in cultural competence at an individual and organisational level improve the experience of care and chance of recovery from schizophrenia in Black and Minority Ethnic groups, and reduce staff burnout?
Does statin use reduce the risk of hip fracture?
Does stem cell technology (e.g. for hair cell regeneration) provide an effective pipeline to develop new medical interventions for treating tinnitus?
Does strontium ranelate increase vascular and neurological side-effects in postmenopausal osteoporosis?
Does sunlight exposure reduce acne severity?
Does switching from brand-name to generic antiepileptic epilepsy drugs increase risk of seizures?
Does systemic HRT use in women whose primary complaint was not urinary incontinence worsen urinary symptoms?
Does taking steroids for asthma cause depression, or add to feeling depressed?
Does taking steroids for asthma stop me losing weight?
Does Tegretol cause balance problem in schizophrenia?
Does testing for allergies lead to better treatment for children with asthma?
Does the addition of counters to inhalers for asthma improve use by the patient?
Does the addition of positron emission tomography/computed tomography (PET/CT) to the routine investigation and assessment of patients with melanoma yield clinical and economic benefits?
Does the addition of psychological interventions (e.g. counselling, support) to patients receiving cosmetic camouflage improve their quality of life?
Does the addition of the oral agent metformin to insulin treatment in children and young people with type 1 diabetes improve outcomes?
Does the addition of zinc to topical erythromycin confer additional benefit in the treatment of acne?
Does the lack of knowledge of the range of treatments for different types of prostate cancer affect outcomes?
Does the management of co-existing neck problems improve outcomes for patients with balance disorders?
Does the method of insulin delivery (injection vs. pump) have any impact on rates of complications?
Does the pain of blood glucose testing affect the willingness of patients, especially children, to monitor their blood glucose levels?
Does the provision of specialists/cancer support groups or specialist health care workers who provide more information on prostate cancer treatment improve outcomes?
Does the way information is provided affect quality of diagnosis, choice of appropriate treatment or outcome for patients with prostate cancer?
Does the way information is provided to patients with mental health conditions effect the outcome of treatment?
Does TNF-blockade therapy exacerbate psoriatic arthritis?
Does tooth brushing influence the development and progression of non-inflammatory gingival recession?
Does treatment for stress and panic reduce asthma attacks?
Does treatment of periodontal disease improve glycaemic control in people with diabetes?
Does treatment of type 1 diabetics by specialists (e.g. doctors, nurses, dieticians, podiatrists, ophthalmologists and psychologists) trained in person-centred skills provide better blood glucose control, patient satisfaction and self-confidence in management of type 1 diabetes, compared to treatment by non specialists with standard skills?
Does treatment with immunosuppressants help patients with vitiligo?
Does under treatment of pernicious anaemia cause cyclic cognitive impairment for patients?
Does unopposed oestrogen therapy have a protective effect against osteoarthritis?
Does using inhalers for asthma cause acid indigestion?
Does using smokeless tobacco stop the incidence of oropharyngeal cancer and periodontal disease?
Does variation in treatment for patients with psychosis, which is often trail and error, affect compliance?
Does Vitamin D production, following exposure to sunlight provide protection against prostate cancer?
Does Yoga help in asthma?
Dopamine agonists for hyperprolactinaemia
Dopamine agonists for restless legs syndrome
Dopamine versus placebo for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Dopexamine versus placebo for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Dosages scheduling of taxanes and the optimal use of taxanes in early breast cancer
Dose regimens, length of treatment, and duration of response of oestrogen and progesterone add-back therapy in preventing bone mineral density loss in patients taking gonadotrophin-releasing hormone analogues for endometriosis
Doses and administration routes for individual triptans and acute cluster headaches
Double-bundle versus single-bundle reconstruction for anterior cruciate ligament rupture in adults
Down titration and discontinuation strategies of tumor necrosis factor blocking agents for rheumatoid arthritis in patients with low disease activity
Doxycycline for hip or knee osteoarthritis
Drama therapy for schizophrenia or schizophrenia-like illnesses
DRCgs for treating paracoccidioidomycosis
Dressings and securement devices for central venous catheters (CVC)
Dressings for superficial and partial thickness burns
Dressings for the prevention of surgical site infection
Dressings for treating foot ulcers in people with diabetes: an overview of systematic reviews
Driving is a risk in patients with sleep-related epilepsy
Drug therapies for reducing gastric acidity in people with cystic fibrosis
Drug therapy for delirium in terminally ill adult patients
Drug therapy for nocturia
Drug therapy for preventing post-dural puncture headache
Drug therapy for symptoms associated with anxiety in adult palliative care patients
Drug therapy for the management of cancer related fatigue
Drug therapy for treating post-dural puncture headache
Drug treatment for nocturnal enuresis
Drug treatment for spinal muscular atrophy type I
Drug treatment for spinal muscular atrophy types II and III
Drug treatment for troublesome postural hypotension in people with diabetes and autonomic neuropathy
Drugs and pacemakers for vasovagal, carotid sinus and situational syncope
Drugs for amoebic colitis
Drugs for nocturia in adults
Drugs for nocturnal enuresis in children (other than desmopressin and tricyclics)
Drugs for preventing red blood cell dehydration in people with sickle cell disease
Drugs for the treatment of nausea and vomiting in adult patients in the emergency department setting
Drugs for treating giardiasis
Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis
Drugs to treat urinary incontinence in the elderly
Dry bed training for nocturnal enuresis
Duloxetine depression
Duloxetine versus other anti-depressive agents for depression
Duration of treatment for asymptomatic bacteriuria during pregnancy
Dynamic exercise programs (aerobic capacity and/or muscle strength training) in rheumatoid arthritis
Ear drops for the removal of ear wax
Early (sentinel lymph node biopsy-guided) versus delayed lymphadenectomy in melanoma patients with lymph node metastases
Early additional food and fluids for healthy breastfed full-term infant
Early administration of inhaled corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonates
Early amniotomy and early oxytocin for prevention of, or therapy for, delay in first stage spontaneous labour compared with routine care
Early compared with delayed oral fluids and food after caesarean section
Early developmental intervention programmes post-hospital discharge to prevent motor and cognitive impairments in preterm infants
Early erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants
Early excision and grafting for burns
Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)
Early intervention with oral isotretinoin versus alternative treatments for moderate or mild acne
Early intervention with systemic treatments for psoriasis
Early lens extraction compared to standard treatment in acute primary angle closure
Early prediction of outcome of activities of daily living after stroke
Early pregnancy assessment units
Early removal versus expectant management of central venous catheters in neonates with bloodstream infection
Early routine endoscopic retrograde cholangiopancreatography strategy versus early conservative management strategy in acute gallstone pancreatitis
Early skin-to-skin contact for mothers and their healthy newborn infants
Early treatment of preclinical hypothyroidism
Early trophic feeding versus enteral fasting for very preterm or very low birth weight infants
Early use of inhaled corticosteroids in the emergency department treatment of acute asthma
Early versus delayed dressing removal for surgical wounds
Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis
Early versus delayed refeeding for children with acute diarrhoea
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome
Early versus late antiepileptic drug withdrawal for people with epilepsy in remission
Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants
Early versus late tracheostomy for critically ill patients
Economic incentives to enhance safety behaviour in workers for preventing occupational injuries
ECT for schizophrenia
Eculizumab for treating patients with paroxysmal nocturnal hemoglobinuria
Edaravone for acute intracerebral haemorrhage
Edaravone for acute ischaemic stroke
Education for contraceptive use by women after childbirth
Education interventions for adults who attend the emergency room for acute asthma
Education of health professionals for preventing diabetic foot ulceration
Education of patients about to undergo laparoscopic cholecystectomy
Educational games for health professionals
Educational interventions for adults to prevent readmission and complications following cardiovascular surgery;Symptoms
Educational interventions for asthma in adults
Educational outcomes of atomoxetine in childhood attention deficit-hyperactivity disorder (ADHD)
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naive individuals
Effect of antibiotic treatment on the results of serological tests for Lyme disease
Effect of cocoa on blood pressure
Effect of duration (3 vs. 6 months) of long-term pituitary down-regulation before in vitro fertilisation for women with endometriosis on pregnancy rates
Effect of gastric banding on gastro-oesophageal reflux symptoms
Effect of lip bumpers on mandibular arch dimensions
Effect of longer-term modest salt reduction on blood pressure
Effect of near vision tasks on visual acuity in children with amblyopia
Effect of partogram use on outcomes for women in spontaneous labour at term
Effect of phenytoin and phenobarbital on bone mineral density in children
Effect of restricted pacifier use in breastfeeding term infants for increasing duration of breastfeeding
Effect of steroidal contraceptives on bone fractures in women
Effect of stimulant medication on gray matter volumes in attention deficit-hyperactivity disorder (ADHD) patients
Effect of time from infection to commencement of treatment on Lyme disease outcomes
Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes
Effective interventions for managing physical health of people with schizophrenia in general practice
Effective interventions for preventing and treating kidney disease in Henoch-Schonlein Purpura (HSP)
Effective interventions for preventing infection in nephrotic syndrome
Effective interventions for primary vesicoureteric reflux
Effective interventions to prevent bone disease in kidney transplant recipients
Effective methods of communication at first consultation visit for women with breast cancer?
Effective physical interventions to treat depression in dialysis patients
Effective psychosocial interventions to treat depression in dialysis patients
Effective treatments for truncal acne
Effectiveness and acceptability of interventions for moist desquamation in radiotherapy patients
Effectiveness and impact of consumer education initiatives for urinary incontinenece
Effectiveness and safety of first-line tenofovir + emtricitabine + efavirenz for patients with HIV
Effectiveness of a second acupuncture treatment in improving migraine
Effectiveness of antiretroviral therapy in HIV-infected children under 2 years of age
Effectiveness of debridement of diabetic foot ulcers
Effectiveness of different nursing handover styles for ensuring continuity of information in hospitalised patients
Effectiveness of different types of acupuncture for migraine prophylaxis
Effectiveness of early in comparison to late(r) treatment in children with amblyopia or its risk factors
Effectiveness of external inspection of compliance with standards in improving healthcare organisation behaviour, healthcare professional behaviour or patient outcomes
Effectiveness of lower-dose combined oral contraceptives in women with IBD following bowel resection
Effectiveness of Nicotine Replacement Therapy in Reducing the Risk of Nicotine Exposure in Pregnant Minority Smokers
NCT00341432
Pilot study of nicotine replacement for smoking cessation during pregnancy.
NCT00888979
Effectiveness of nitrates compared to percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) for stable angina
Effectiveness of organisational infrastructures to promote evidence-based nursing practice
Effectiveness of posterior decompression techniques compared to conventional laminectomy for lumbar stenosis
Effectiveness of systematic screening for the detection of atrial fibrillation
Effectiveness of the Valsalva Manoeuvre for reversion of supraventricular tachycardia
Effectiveness of the various components of preconception counselling to reduce adverse pregnancy outcome in women with epilepsy
Effectiveness of topical administration of opioids in palliative care
Effectiveness of vocational rehabilitation intervention on the return to work and employment of persons with multiple sclerosis
Effects and safety of periconceptional folate supplementation for preventing birth defects
Effects of etanercept on malignancy for rheumatoid arthritis
Effects of hormonal suppression, either before or after surgery, on endometriosis-associated pain and disease severity
Effects of long acting inhaled anticholinergics on cardiovascular events and mortality among vulnerable subgroups at the highest risk of systemic anticholinergic effects
Effects of long term pituitary down-regulation using GnRH agonists before in vitro fertilisation in women with endometriosis on the incidence of fetal abnormalities
Effects of long term pituitary down-regulation using GnRH agonists before in vitro fertilisation in women with endometriosis on the rate of multiple pregnancy
Effects of oral stimulation for oral feeding in preterm infants
Effects of preventive oral supplementation with iron or iron with folic acid for women following childbirth
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome
Efficacy and safety of Chinese herbal therapies for atopic eczema
Efficacy and safety of coal tar for chronic plaque psoriasis
Efficacy and safety of fibre-enriched formulations in acute pancreatitis compared to fibre-free formulas
Efficacy and safety of Grenz rays for psoriasis
Efficacy and safety of home UVB therapy for psoriasis compared to treatment in hospital
Efficacy and safety of intravenous immunoglobulin for atopic eczema, especially in patients who are not resistant to other systemic treatments
Efficacy and safety of leflunomide for atopic eczema
Efficacy and safety of leukotriene inhibitors (anti-leukotrienes) for atopic eczema
Efficacy and safety of methotrexate for atopic eczema
Efficacy and safety of oral mycophenolate mofetil for atopic eczema
Efficacy and safety of photodynamic therapy for acne
Efficacy and safety of wet-wraps for long-term treatment of atopic eczema
Efficacy of dental prophylaxis (rubber cup) for the prevention of caries and gingivitis
Efficacy of directional-microphone hearing aids
Efficacy of dithranol compared to topical vitamin D preparations (calcipotriol, calcitriol, tacalcitol) for chronic plaque psoriasis
Efficacy of emollients for chronic plaque psoriasis
Efficacy of intranasal corticosteroids for acute sinusitis
Efficacy of programmable analog hearing aids
Efficacy of Psychostimulant Drugs for Amphetamine Abuse or Dependence
Efficacy of retinoids in the treatment of psoriasis
Efficacy of topical salicylic acid for chronic plaque psoriasis
Efficacy, tolerability, and safety of extended-release, topical, and novel anti-muscarinic agents for urinary incontinence in frail and institutionalised older people
Efficacy, tolerability, and safety of medications used to prevent urinary incontinence for extended periods (beyond 6 months)
Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia
Elastic compression stocking for prevention of deep vein thrombosis
Elective repeat caesarean section versus induction of labour for women with a previous caesarean birth
Elective surgery versus clinical observation for focal liver lesions incidentally detected and supposed to be benign
Elective versus symptomatic intravenous antibiotic therapy for cystic fibrosis
Electric fans for reducing adverse health impacts in heatwaves
Electric fans for reducing adverse health impacts in heatwaves
Electrical stimulation with non-implanted electrodes for overactive bladder in adults
Electrical stimulation with non-implanted electrodes for urinary incontinence in adults
Electroconvulsive therapy (ECT) for schizophrenia
Electroconvulsive therapy for the depressed elderly
Electromagnetic field stimulation for treating delayed union or non-union of long bone fractures in adults
Electromagnetic therapy for treating pressure ulcers
Electromagnetic therapy for treating venous leg ulcers
Electromagnetic treatment for urinary incontinence in adults
Electromechanical and robot-assisted arm training for improving generic activities of daily living, arm function, and arm muscle strength after stroke
Electronic cigarettes for smoking cessation and reduction
Electropalatography for articulation disorders associated with cleft palate
Electrotherapy for neck pain
Elemene for the treatment for lung cancer
Elevation of the head during intensive care management in adult patients with severe traumatic brain injury
Email for clinical communication between healthcare professionals
Email for clinical communication between patients/caregivers and healthcare professionals
Email for communicating results of diagnostic medical investigations to patients
Email for the coordination of healthcare appointments and attendance reminders
Email for the provision of information on disease prevention and health promotion
Embolisation for pulmonary arteriovenous malformation
Empiric antibiotic coverage of atypical pathogens for community-acquired pneumonia in hospitalized adults
Empirical antibiotic therapy for febrile neutropenia in pediatric cancer patients
Enamel matrix derivative for periodontal regeneration in teeth with furcation involvement
Endometrial injury in women undergoing assisted reproductive techniques
Endorectal advancement flap vs. other surgical techniques for cryptoglandular or Crohn's fistula-in-ano
Endoscopic balloon dilatation for subglottic or tracheal stenosis
Endoscopic drainage with or without endo-ultrasonography for pancreatic pseudocyst
Endoscopic injection of cyanoacrylate glue versus other endoscopic procedures for acute bleeding gastric varices in patients with portal hypertension
Endoscopic or surgical intervention for painful obstructive chronic pancreatitis
Endoscopic third ventriculostomy (ETV) for idiopathic normal pressure hydrocephalus (iNPH)
Endothelial keratoplasty versus penetrating keratoplasty for Fuchs endothelial dystrophy
Endothelin receptor antagonists for pulmonary arterial hypertension
Endothelin receptor antagonists for subarachnoid hemorrhage
Endovascular repair versus open repair for inflammatory abdominal aortic aneurysms
Endovascular versus conventional medical treatment for uncomplicated chronic type B aortic dissection
Endovascular versus open repair of asymptomatic popliteal artery aneurysm
Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus conventional surgery for great saphenous vein varices
Energy source instruments for laparoscopic colectomy
Enhanced external counterpulsation
Enhanced external counterpulsation (EECP) for stable angina (CCS Grade IV)
Enhanced glucose control for preventing and treating diabetic neuropathy
Enhancing partner support to improve smoking cessation
Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy
Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy
Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy
Enteral iron supplementation in preterm and low birth weight infants
Enteral nutrition compared with glucocorticosteroid treatment in adults and children with Crohn's disease
Enteral tube feeding for cystic fibrosis
Enuresis alarm treatment for children and young people who are partial or non-responders to desmopressin.
Environmental change for preventing asthma
Environmental enrichment for schizophrenia
Enzyme replacement and substrate reduction therapy for Gaucher disease
Enzyme replacement therapy for Anderson-Fabry disease
Enzyme replacement therapy for trimethylaminuria (odour problems)
Enzyme replacement therapy with galsulfase for mucopolysaccharidosis type VI
Enzyme replacement therapy with idursulfase for mucopolysaccharidosis type II (Hunter syndrome)
Ephedrine for myasthenia gravis
Ephedrine for shortening the time to achieve excellent intubation conditions during direct laryngoscopy in adults
Epidermal growth factor receptor blockers for the treatment of ovarian cancer
Epidermal growth factor receptor targeted therapy in locally advanced head and neck squamous cell carcinoma
Epidural blood patching for preventing and treating post–dural puncture headache
Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery
Epidural versus non-epidural or no analgesia in labour
Epinephrine for the resuscitation of apparently stillborn or extremely bradycardic newborn infants
Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis
Ergonomic design and training for preventing work-related musculoskeletal disorders of the upper limb and neck in adults
Ergonomic positioning or equipment for treating carpal tunnel syndrome
Eribulin with vinorelbine for the treatment of locally advanced or metastatic breast cancer
ER-Yag laser plus topical 5-fluorouracil preceding narrow band UVB phototherapy for repigmentation in vitiligo
Erythropoiesis-stimulating agents for anemia in rheumatoid arthritis
Erythropoiesis-stimulating agents for myelodysplastic syndromes
Erythropoietin and Darbepoetin for patients with malignant disease
Erythropoietin for minimising perioperative allogeneic blood transfusion in cardiac surgery
Erythropoietin for preterm infants with hypoxic ischaemic encephalopathy
Erythropoietin or darbepoetin for patients with cancer
Escitalopram versus other antidepressive agents for depression
Eslicarbazepine acetate add-on for drug-resistant partial epilepsy
Ethnically specific and specialist services for people with schizophrenia
Etidronate and risk of upper gastrointestinal injury in osteoporotic fractures
Evening Primrose oil for schizophrenia
Evening versus morning dosing regimen drug therapy for hypertension
Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia
Excitatory amino acid antagonists for acute stroke
Exclusion diets for irritable bowel syndrome
Exclusion diets for preventing atopic eczema in infants at high risk for the development of atopy
Exclusion diets for treating established atopic eczema
Exclusive breast-feeding for preventing atopic eczema in infants at high risk for the development of atopy
Exenterative surgery for recurrent gynaecological malignancies
Exercise and mobilisation interventions for carpal tunnel syndrome
Exercise based rehabilitation for heart failure
Exercise for acutely hospitalised older medical patients
Exercise for depression
Exercise for depression
Exercise for fibromyalgia syndrome
Exercise for improving cardiovascular status in rheumatoid arthritis
Exercise for improving outcomes after osteoporotic vertebral fracture
Exercise for non-alcoholic fatty liver disease
Exercise for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Exercise for older depressed people
Exercise for pregnant women for preventing gestational diabetes mellitus
Exercise for preventing low bone mineral density in children with juvenile rheumatoid arthritis
Exercise for reducing fear of falling in older people living in the community
Exercise for the management of ACL injuries in combination with collatoral ligament and meniscal damage
Exercise for the management of cancer-related fatigue in adults
Exercise for the management of cancer-related fatigue in adults
Exercise in depression
Exercise interventions during recovery from Lyme disease
Exercise interventions for shoulder dysfunction in patients treated for head and neck cancer
Exercise interventions for smoking cessation
Exercise interventions on health-related quality of life for cancer survivors
Exercise interventions on health-related quality of life for people with cancer during active treatment
Exercise prescriptions' as a treatment for depression
Exercise therapy for fatigue in multiple sclerosis
Exercise therapy for schizophrenia
Exercise training for adults with chronic kidney disease
Exercise training undertaken within 12 months following lung resection for patients with non-small cell lung cancer
Exercise-based interventions for conservatively or surgically treated anterior cruciate ligament injuries in adults
Exercises for adolescent idiopathic scoliosis
Exercises for hand osteoarthritis
Exercises for mechanical neck disorders
Exit interviews to reduce turnover amongst healthcare professionals
Expectant care versus surgical treatment for miscarriage
Expedited versus conservative approaches for vaginal delivery in breech presentation
Extended discussion of information for informed consent for participation in clinical trials
Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin treatment for 48 weeks in chronic hepatitis C genotype 1 infected slow-responder adult patients
External cephalic version for breech presentation at term
External counterpulsation for acute ischaemic stroke
External fixation methods for treating distal radial fractures in adults
Extracorporeal membrane oxygenation for critically ill adults
Extracorporeal photopheresis versus alternative treatment for chronic graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients
Extracorporeal shock wave lithotripsy (ESWL) versus ureteroscopic management for ureteric calculi
Extraction of primary (baby) teeth for unerupted palatally displaced permanent canine teeth in children
Extramedullary fixation implants and external fixators for extracapsular hip fractures in adults
Extra-urethral (non-circumferential) retropubic adjustable compression devices for stress urinary incontinence
Face to face interventions for informing or educating parents about early childhood vaccination
Face-down positioning or posturing after macular hole surgery
Face-to-face interventions for promoting physical activity
Face-to-face versus remote and web 2.0 interventions for promoting physical activity
Facial aesthetics: is botulinum toxin treatment effective and safe?
Facilitated self-help for the treatment of mild anxiety and depressive disorders in adults with autism
Factors associated with non-adherence to oral medication for inflammatory bowel disease
Factors influencing the regular use of prophylactic medication for those with asthma.
Factors that impact on the use of mechanical ventilation weaning protocols in critically ill adults and children: a qualitative evidence-synthesis
Famciclovir and other new antiviral agents for preventing postherpetic neuralgia
Family interventions for the families of people with schizophrenia presenting for the first time
Family therapy for depression
Family therapy for schizophrenia
Family-centred care for hospitalised children aged 0-12 years
Fast track surgery versus conventional recovery strategies for colorectal surgery
Fast-track cardiac care for adult cardiac surgical patients
Febuxostat for treating chronic gout
Feedback or biofeedback to augment pelvic floor muscle training for urinary incontinence in women
Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and palate
Feeding interventions for improving the physical and psychosocial health of disadvantaged children aged three months to five years
Femoral nerve blocks for acute postoperative pain after knee replacement surgery
Fenoldopam for preventing and treating acute kidney injury
Fermented milk for hypertension
Fertility awareness-based methods for contraception
Fetal assessment methods for improving neonatal and maternal outcomes in preterm prelabour rupture of membranes
Fetal electrocardiogram (ECG) for fetal monitoring during labour
Fetal manipulation for facilitating tests of fetal wellbeing
Fibrates for primary prevention of cardiovascular disease events
Fibrinogen depleting agents for acute ischaemic stroke
Fibrinolytic therapy for intraventricular hemorrhage in adults
First trimester progesterone prophylaxis to increase the live birth rate in women with unexplained recurrent miscarriages
First-line beta-blockers versus other anti-hypertensive medications for chronic type B aortic dissections
First-line chemotherapy in low-risk gestational trophoblastic neoplasia
First-line docetaxel chemotherapy for castrate-resistant prostate cancer
First-line tandem high-dose chemotherapy and autologous stem cell transplantation versus single high-dose chemotherapy and autologous stem cell transplantation in multiple myeloma, a systematic review of controlled studies
First-line treatment of advanced epidermal growth factor receptor (EGFR) mutation positive non-squamous non-small cell lung cancer
Fish oil for schizophrenia
Fish oil supplementation for psoriasis
Fish oil supplements for rheumatoid arthritis
Fish oil supplements for the prevention and treatment of hypertension in adults
Fixed courses of antibiotics versus continuing until all symptoms are resolved in Lyme disease
Fixed-dose combination therapy for the prevention of cardiovascular disease
Fixed-dose combinations of drugs versus single drug formulations for treating pulmonary tuberculosis
Flossing for the management of periodontal diseases and dental caries in adults
Flow-regulated versus differential pressure-regulated shunt valves for adult patients with normal pressure hydrocephalus
Fluid replacement therapy for acute episodes of pain in people with sickle cell disease
Fluid restriction and prophylactic indomethacin versus prophylactic indomethacin alone for prevention of morbidity and mortality in extremely low birth weight infants
Fluid therapy for acute bacterial meningitis
Fluids and diuretics for acute ureteric colic
Flunisolide for chronic asthma
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children
Fluoxetine for depression
Fluoxetine for multiple sclerosis
Flupenthixol versus placebo for schizophrenia
Flutamide for treatment of acne in women
Fluticasone versus HFA-beclomethasone dipropionate for chronic asthma in adults and children
Fluvoxamine for depression
Foam dressings for healing diabetic foot ulcers
Foam dressings for venous leg ulcers
Focal cryoablation for localised prostate cancer
Focal therapy using high-intensity focused ultrasound (HIFU) for localised prostate cancer
Foetal safety of nasal decongestants as second line therapy for pregnant women with allergic rhinitis
Folate Augmentation of Treatment - Evaluation for Depression: randomised controlled trial (FolATED)
Folic acid for fragile X syndrome
Folic acid supplementation during pregnancy for maternal health and pregnancy outcomes
Folic or folinic acid supplementation for preventing methotrexate-associated haematological side-effects in inflammatory disease
Follicular flushing during oocyte retrieval in assisted reproductive techniques
Follow-up for improving psychological well being for women after a miscarriage
Follow-up strategies for patients treated for non-metastatic colorectal cancer
Food fortification with calcium and vitamin D: impact on health outcomes
For an acute exacerbation of asthma, a patient has taken 150mg prednisolone per day for 1 week, and is now slowly being weaned off. Is there any information on acute or long term damage?
For infants born with cleft lip/palate what is the most effective care pathway for promoting mother/infant bonding?
For patients with an acute painful sickle cell episode, are non-pharmacological interventions, such as massage, effective in improving their recovery from the episode?
For patients with oral cancer and a clinically N0 neck undergoing surgery to the primary site, in which circumstances is it beneficial to carry out a simultaneous prophylactic neck dissection.
For women with a high risk pregnancy, does taking marine oil supplements prolong gestation?
For women with high blood pressure during pregnancy, what are the benefits and risks of rest in hospital compared with rest at home?
For women with high blood pressure during pregnancy, what are the short and long term effects of antihypertensive drugs for both the mother and the child?
For women with normal blood pressure during pregnancy, does rest help prevent pre-eclampsia and its complications?
For women with pre-eclampsia complicated by HELLP (Haemolysis, Elevated Liver enzymes, and Low Platelets) syndrome, is treatment with steroids beneficial?
For women with pre-eclampsia, does Chinese herbal medicine prevent complications, and is it safe?
For women with raised blood pressure during pregnancy, at what level of blood pressure does antihypertensive medication become worthwhile?
For women with raised blood pressure during pregnancy, what are the advantages and disadvantages of wearing a device to measure blood pressure over a period of time, usually 24 hours, compared to conventional measuring of blood pressure in clinic?
For women with troublesome fibroids who wish to retain or enhance their fertility, is myomectomy or embolisation better?
Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma
Fortification of maize flour with iron for preventing anaemia and iron deficiency in populations
Fortification of staple foods with vitamin A for preventing vitamin A deficiency
Fortifying food with calcium during pregnancy, rather than taking calcium tablets to prevent pre-eclampsia.
Framing of health information messages
Frequency modulation (FM) system in auditory processing disorder
Fresh frozen femoral head allograft compared to processed femoral head allograft in revision hip arthroplasty
FSH replaced by low-dose hCG in the late follicular phase versus continued FSH for assisted reproductive techniques
FSH replaced by low-dose hCG in the late follicular phase versus FSH alone for assisted reproductive techniques
Functional analysis-based interventions for challenging behaviour in dementia
Functional electrical stimulation (FES) versus conventional aerobic exercise (CA) in chronic heart failure (CHF) patients
Functional endoscopic balloon dilation of sinus ostia for chronic rhinosinusitis
Functional endoscopic sinus surgery for chronic rhinosinusitis
Fusion versus conservative management for low-grade isthmic spondylolisthesis
Gabapentin add-on for drug-resistant partial epilepsy
Gabapentin for chronic neuropathic pain and fibromyalgia in adults
Galantamine for vascular cognitive impairment
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke
Gamma nail or sliding hip screw for the treatment of intertrochanteric fracture
Ganoderma lucidum (Reishi mushroom) for cancer treatment
Garlic for diabetes mellitus
Garlic for peripheral arterial occlusive disease
Garlic for the common cold
Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients
Garlic, or garlic preparations, to prevent pre-eclampsia and its complications.
Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery
Gemcitabine for unresectable, locally advanced or metastatic bladder cancer
Gene therapy for sickle cell disease
General health checks in adults for reducing morbidity and mortality from disease
General physical health advice for people with serious mental illness
Genetic testing before anticoagulation
Genital ulcer disease treatment for reducing sexual acquisition of HIV
Ginkgo biloba extract for age-related macular degeneration
Ginkgo biloba extract for age-related macular degeneration
Ginkgo biloba for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Ginkgo biloba for tinnitus
Ginkgo special extract EGb 761® for vertigo
Ginseng for cognition
Glucagon-like peptide analogues for type 2 diabetes mellitus
Glucocorticoid with cyclophosphamide for paraquat-induced lung fibrosis
Glucocorticoids for acute viral bronchiolitis in infants and young children
Glucocorticoids for the treatment of anaphylaxis
Glucocorticosteroids for alcoholic hepatitis
Glucocorticosteroids for primary sclerosing cholangitis
Glucose for the management of procedural pain in neonates
Glucose lowering therapies for chronic kidney disease and kidney transplantation
Glucose targets for preventing diabetic kidney disease and its progression
Glutamine supplementation for critically ill adults
Glutamine supplementation for young infants with severe gastrointestinal disease
Glutamine supplementation to prevent morbidity and mortality in preterm infants
Glycerin laxatives for prevention or treatment of feeding intolerance in very low birth weight infants
GnRH agonists or OCPs for symptom relief in women with endometriosis-associated pain
Gonadotrophin-releasing hormone agonist protocols for pituitary suppression in assisted reproduction
Gonadotrophin-releasing hormone analogues for pain associated with endometriosis
Gonadotrophins for ovulation induction in women with polycystic ovarian syndrome
GP-led melanoma follow up for improved patient satisfaction
Granulocyte-colony stimulating factor for acute liver failure or acute-on-chronic liver failure
Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections
Green and black tea for the primary prevention of cardiovascular disease
Green tea for the prevention of gastrointestinal cancer
Green tea for weight loss and weight maintenance in overweight or obese adults
Group versus conventional antenatal care for women
Group-based parent training programmes for improving parental psychosocial health
Growth hormone for in vitro fertilization
Growth monitoring and promotion (GMP) for children in low and middle income countries
Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis
Habit retraining in the management of urinary incontinence
Haematological interventions for treating disseminated intravascular coagulation during pregnancy and postpartum
Haemodialysis duration, frequency and intensity for end-stage kidney disease
Haemodilution for acute ischaemic stroke
Haemodilution for retinal vein occlusion
Haemodilution to decrease blood loss and blood transfusion requirements for liver resection
Haemoglobin target in the treatment of anaemia associated with Chronic Kidney Disease
Haemophilus influenzae oral vaccination for preventing acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease
Haemostatic drugs for traumatic brain injury
Haloperidol for long-term aggression in psychosis
Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation)
Haloperidol versus chlorpromazine for schizophrenia
Haloperidol versus first generation antipsychotics for schizophrenia
Harmonic scalpel versus other surgical procedures for tonsillectomy
Has the adoption of target times for prostate cancer referrals and treatment had a beneficial effect on outcomes?
Head massage for tinnitus
Health checks for people with intellectual disabilities to reduce morbidity and premature mortality
Healthcare financing systems for increasing the use of tobacco dependence treatment
Heat therapies for acne
Heavy metal chelation for Lyme disease
Helicobacter pylori eradication for Parkinson's disease
Helicopter emergency medical services for adults with major trauma
Helminth therapy (worms) for allergic rhinitis
Hematopoietic stem cell transplantation for Gaucher disease
Hematopoietic stem cell transplantation for people with ?-thalassaemia major
Hemodilution to improve visual acuity in branch retinal vein occlusion
Hemodilution to improve visual acuity in central retinal vein occlusion
Heparin and related substances for preventing diabetic kidney disease
Hepatic late adverse effects after antineoplastic treatment for childhood cancer
Hepatic lymph nodes during resection of liver metastases from colorectal cancer
Hepatitis A immunisation in persons not previously exposed to hepatitis A
Hepatitis B immune globulin for preventing hepatitis B recurrence after liver transplantation
Hepatitis B vaccination during pregnancy for preventing infant infection
Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection
Hepatotoxic effects of acetaminophen in alcoholics when taken for more than a few days
Herbal and dietary therapies for primary and secondary dysmenorrhoea
Herbal interventions for allergic rhinitis
Herbal interventions for chronic asthma in adults and children
Herbal medications for Ménière's disease
Herbal medicines for advanced colorectal cancer
Herbal medicines for the treatment of rhinosinusitis
Herbal medicines for viral myocarditis
Herbal preparations for uterine fibroids
Herbal remedies (including cannabis and cannabinoids) for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Herbal therapy for treating rheumatoid arthritis
High altitude therapy for asthma
High dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with early poor prognosis breast cancer
High dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with metastatic breast cancer
High dose versus low dose oxytocin for augmentation of delayed labour
High flow nasal cannula for respiratory support in preterm infants
High flow nasal cannula therapy for respiratory support in children
High flow nasal cannulae for respiratory support in adult intensive care patients
High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia
High-carbohydrate, high-protein, low-fat versus low-carbohydrate, high-protein, high-fat enteral feeds for burns
High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma
High-dose dual therapy of omeprazole and amoxycillin for Helicobacter pylori eradication in patients with gastric MALT lymphoma
High-dose therapy with autologous stem cell transplantation versus chemotherapy or immuno-chemotherapy for follicular lymphoma in adults
High-dose versus non-high-dose proton pump inhibitors for bleeding peptic ulcers in seriously ill patients
Higher versus lower oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth
High-flux versus low-flux membranes for end-stage kidney disease
High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome
High-intensity focused ultrasound (HIFU) for atrial fibrillation
High-intensity versus low-intensity physical activity or exercise in patients with hip or knee osteoarthritis
High-volume haemofiltration for sepsis
Hip protectors for preventing hip fractures in elderly nursing home residents
Histamine H2-receptor antagonists for urticaria
Histamine type 2 receptor antagonists as adjuvant treatment for resected colorectal cancer
HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass
Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma
Holding chambers versus nebulisers for inhaled drugs in chronic asthma
Holding chambers versus nebulisers for inhaled steroids in chronic asthma
Home care by outreach nursing for chronic obstructive pulmonary disease
Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age
Home safety education and provision of safety equipment for injury prevention
Home uterine monitoring for detecting preterm labour
Home versus hospital intravenous antibiotic therapy for cystic fibrosis
Home versus hospital-based intravenous antibiotic treatment for Lyme disease
Home versus hospital-based phototherapy for the treatment of non-haemolytic jaundice in infants more than 37 weeks gestation
Home visits during pregnancy and after birth for women with an alcohol or drug problem
Home-based child development interventions for preschool children from socially disadvantaged families
Home-based educational interventions for children with asthma
Home-based physiotherapy interventions to reduce breathlessness during activities of daily living in severe COPD
Home-based therapy programmes for upper limb functional recovery following stroke
Homeopathic Oscillococcinum for preventing and treating influenza and influenza-like illness
Homeopathy for asthma
Homeopathy for atopic eczema
Homeopathy for Lyme disease
Homeopathy for Ménière's disease
Homeopathy for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Homeopathy for treatment of irritable bowel syndrome
Homeopathy in the treatment of allergic rhinitis
Homework, organisation, and planning skills (HOPS) for school children with attention deficit-hyperactivity disorder (ADHD)
Honey and lozenges for children with non-specific cough
Honey as a topical treatment for wounds
Honey for acute cough in children
Hormonal and intrauterine methods for contraception for women aged 25 years and younger
Hormonal contraception for women exposed to HIV infection
Hormonal contraceptives for contraception in overweight or obese women
Hormonal therapy in advanced or recurrent endometrial cancer
Hormonal versus non-hormonal contraceptives in women with diabetes mellitus type 1 and 2
Hormone replacement for osteoporosis in women with primary biliary cirrhosis
Hormone replacement therapy (HRT) following bilateral oophorectomy with or without hysterectomy in women with symptoms of endometriosis
Hormone therapy for preventing cardiovascular disease in post-menopausal women
Hormone therapy in postmenopausal women and risk of endometrial hyperplasia
Horse chestnut seed extract for chronic venous insufficiency
Hospital at home for acute exacerbations of chronic obstructive pulmonary disease
Hospital at home: home-based end of life care
Hospital nurse staffing models and patient and staff-related outcomes
House dust mite control measures to control asthma symptoms
Household interventions for preventing domestic lead exposure in children
Housing improvements for health and associated socio-economic outcomes
How accurate is positron emission tomography/computed tomography for identifying residual tumours in adults with testicular germ cell tumours?
How accurate is the Gleason system as a mechanism for grading prostate cancer?
How and when should immunosuppression in kidney transplant patients be reduced?
How beneficial is surgery for cervical radiculopathy and myelopathy?
How best to prepare people with diabetes for use of an insulin pump
How big a problem is non-alcoholic fatty liver disease?
How can awareness of and prevention of hypoglycaemia in type 1 diabetes be improved?
How can case-finding for hepatitis B and C be improved?
How can I check and detect early signs of prostate cancer myself?
How can I lose weight when taking prednisolone for asthma?
How can I manage the effects of corticosteroids, which I take for asthma, on my voice, and what effect is it having in the long term?
How can insulin delivery devices, such as pens, be improved to display unambiguously that insulin has been delivered?
How can insulin dosage for type 1 diabetes best be adjusted around exercise and/or stress?
How can interventions which have been proven effective in other countries be assessed for their cultural relevance to the UK?
How can non-invasive, accurate, real-time Continuous Glucose Monitoring be achieved?
How can over-treatment for prostate cancer be prevented by identifying and excluding the treatment of harmless tumours? (Tigers & Pussycats)
How can over-treatment for prostate cancer be prevented by indentifying and excluding the treatment of harmless tumours?
How can people identify which is the correct needle length for them when injecting insulin for diabetes?
How can reflux be treated best in babies with cleft lip/palate?
How can the fetus at risk of intrauterine death be identified in women with diabetes?
How can the uptake of hepatitis C treatment be improved among all populations in primary and secondary care?
How can tinnitus be effectively managed in people who are Deaf or who have a profound hearing loss?
How can we improve the diagnosis of cleft palate?
How can we maintain or improve cognitive function for people with central nervous system (CNS) tumours?
How can we make doctors better aware of rare anti-epileptic drug side effects?
How could existing guidance on evaluating complex, population-wide interventions be most usefully adapted and applied to approaches that aim to increase rates of walking and cycling?
How critical is the timing of taking epilepsy medication?
How do anti-epileptic drugs affect personality?
How do COX-2 selective NSAIDs compare to non-selective NSAIDs for arthritis?
How do epilepsy medications affect communication skills?
How do epilepsy medications affect the stomach in the long term?
How do I choose which insulin pen is best for me?
How do I know if the inhaled steroids my child is prescribed for their asthma are being delivered in the right dose and if their technique is adequate?
How do I know when my asthma is bad enough to seek medical treatment and who should I go to?
How do I manage my asthma symptoms during my menstrual cycle?
How do individual and local factors influence the effectiveness of specific approaches to encouraging walking or cycling?
How do rates of adherence differ with different complexities of treatment regimen for the management of type 2 diabetes?
How do tricyclics, duloxetine, glabapentin and pregabalin compare in their reduction of pain caused by diabetic neuropathy?
How do we get to the real story from people with type 1 diabetes presenting in clinic and how can we tell when they are wanting to or needing to present as compliant?
How do we improve adherence to oral antipsychotic drugs?
How do we prevent radical prostatectomy causing urinary incontinence?
How do you get children with asthma to take their medication regularly?
How do you reduce pain for patients with dystrophic epidermolysis bullosa patients who are constipated?
How does natural sunlight interact with other treatments for vitiligo?
How does the initiation and titration of long-acting insulin affect health-related quality of life in patients with type 2 diabetes?
How does topical diclofenac compare with eltenac in osteoarthritis?
How does type of surgery and rehabilitation affect the outcome of anterior cruciate ligament injuries?
How early in pregnancy to start taking aspirin for women at moderate or high risk of pre-eclampsia to reduce the incidence of pre-eclampsia, IUGR and pre-term birth
How early is early to give statins for people with diabetes?
How effective and safe are IV immunoglobulins for eczema?
How effective and safe are antihistamines in treating eczema?
How effective and safe are dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) for osteoarthritis?
How effective and safe is thymopentin for eczema?
How effective are alternative or complimentary therapies for nocturia?
How effective are antibiotics for trimethylaminuria?
How effective are anti-oxidants when combined with mitochondrial stimulating cream in treating vitiligo?
How effective are anti-oxidants when combined with tablets such as phenylalanine in treating vitiligo?
How effective are bandages and splints in terms of avoiding sindactylia in patients with dystrophic epidermolysis bullosa?
How effective are contact lenses in improving quality of life and to prevent sequelae for patients with dystrophic epidermolysis bullosa?
How effective are different types of dressings in curing wounds in dystrophic epidermolysis bullosa patients?
How effective are different types of dressings in producing new skin that is more resistant to injury in patients with dystrophic epidermolysis bullosa?
How effective are drug based therapies for nocturia?
How effective are eye drops and ointments to improve Quality of life and to prevent sequelae for patient with dystrophic epidermolysis bullosa?
How effective are herbal remedies in treating vitiligo?
How effective are hormones or hormone related substances that stimulate pigment cells (MSH analogues, afamelanotide) in treating vitiligo?
How effective are interventions to promote social and emotional wellbeing among, and reduce the vulnerability of, different groups of vulnerable children aged under 5 years?
How effective are interventions to reduce skin infections in the management of eczema?
How effective are mobilsation strategies after hip fracture in adults?
How effective are moisturizers in improving itch and preventing new wounds in patients with dystrophic epidermolysis bullosa?
How effective are other complementary therapies (e.g. aloe vera, UNANI) in treating vitiligo?
How effective are patellar taping and bracing for knee osteoarthritis?
How effective are probiotics for the treatment of eczema?
How effective are prosthesis in improving quality of life after amputations in patient with dystrophic epidermolysis bullosa?
How effective are psychological therapies and peer support groups for adults with psoriasis and psoriatic arthritis?
How effective are SAD light boxes in treating vitiligo?
How effective are steroid creams in treating vitiligo?
How effective are steroid tablets in treating vitiligo?
How effective are surgical interventions for overactive bladder?
How effective are topical antibacterial treatments in hastening healing, preventing infection, increasing quality of life, decreasing smell in patients with dystrophic epidermolysis bullosa?
How effective is a "tumour early diagnosis protocol" in patients with dystrophic epidermolysis bullosa?
How effective is a choline elimination diet for treating trimethylaminuria?
How effective is a specialized feeder in preventing oral lesions in babies in patient with dystrophic epidermolysis bullosa?
How effective is aloe vera to hasten wound healing for patients with dystrophic epidermolysis bullosa?
How effective is ambulatory continuous blood glucose monitoring in pregnancies complicated by diabetes?
How effective is cosmetic camouflage for the management of vitiligo?
How effective is cream containing Vitamin D analogues (calcipotriol and tacalcitol) in the treatment of vitiligo?
How effective is education into the use of cosmetic camouflage for the management of vitiligo?
How effective is electronic surveillance vs. observation of hand washing to check compliance?
How effective is hand physiotherapy to avoid or delay syndactilia for patients with dystrophic epidermolysis bullosa?
How effective is hormone replacement therapy (HRT) in treating vitiligo?
How effective is laser therapy in treating vitiligo?
How effective is laser therapy when combined with creams or ointments (e.g. steroid cream) in treating vitiligo?
How effective is levamisole in treating vitiligo?
How effective is levamisole taken by mouth when combined with creams or ointments (e.g. steroid cream) in treating vitiligo?
How effective is melagenina in treating vitiligo?
How effective is micropigmentation in treating vitiligo?
How effective is natural sunlight in achieving repigmentation of the skin in patients with vitiligo?
How effective is nerve stimulation in treating vitiligo?
How effective is patient information in improving management, self care and adherence with treatment in patients with atopic eczema?
How effective is piperine (black pepper) cream in treating vitiligo?
How effective is piperine taken by mouth in treating vitiligo?
How effective is plant-based catalase/dismutase in treating vitiligo?
How effective is psoralen cream/ointment combined with exposure to natural sunlight (topical PUVAsol) in treating vitiligo?
How effective is psychosocial care for people with diabetes?
How effective is PUVA therapy in treating vitiligo?
How effective is PUVA therapy when combined with other creams and ointments in treating vitiligo?
How effective is PUVA therapy when combined with other medicines taken by mouth in treating vitiligo?
How effective is radiotherapy in localised versus widespread Post Transplant Lymphoproliferative Disorders?
How effective is skin grafting in treating vitiligo?
How effective is specialist clothing in treating eczema?
How effective is taking psoralen by mouth combined with exposure to natural sunlight (oral PUVAsol) in treating vitiligo?
How effective is the addition of occupational therapy-physiotherapy to decrease contractures, osteoporosis, disability for patients with dystrophic epidermolysis bullosa?
How effective is the addition of pressure reliving devices to decrease the appearance of new lesions for patients with dystrophic epidermolysis bullosa?
How effective is the avoidance of high temperatures in preventing lesions in patients with dystrophic epidermolysis bullosa?
How effective is the introduction of foreign bodies (such as intestinal worms) in treating vitiligo?
How effective is the long term use of systemic antibiotics (chronic or pulsatile) for patients with dystrophic epidermolysis bullosa?
How effective is the specialist training for GPs who assess and prescribe treatments for eczema, including training on when to refer to a dermatologist?
How effective is the use of adjuvant or neoadjuvant radiotherapy and chemotherapy in the treatment of non-melanoma sink cancer in patients with dystrophic epidermolysis bullosa?
How effective is the use of pureed food to decrease oral and esophageal lesions for patients with dystrophic epidermolysis bullosa?
How effective is the use of vibrating platforms to decrease contractures, osteoporosis, disability in patients with dystrophic epidermolysis bullosa?
How effective is transvaginal ultrasound for the detection of congenital malformations in women with diabetes and coexisting obesity?
How effective is urinary diversion surgery for urinary incontinence for people with spina bifida?
How effective is using 72 hour blood glucose monitoring and educating individuals in the management of type 1 diabetes?
How effective is UVA light therapy in treating vitiligo?
How effective is UVA light therapy when combined with creams or ointments (e.g. khellin, lactic acid, steroid creams) in treating vitiligo?
How effective is UVA light therapy when combined with treatments taken by mouth (e.g. phenylalanine, khellin) in treating vitiligo?
How effective is UVB light therapy in treating vitiligo?
How effective is UVB light therapy when combined with creams or ointments (e.g. steroid creams) in treating vitiligo?
How effective is UVB light therapy when combined with medicines taken by mouth in treating vitiligo?
How effective is UVB light therapy when combined with the needling technique in treating vitiligo?
How effectives are oral motor exercises in order to prevent microstomia in patient with dystrophic epidermolysis bullosa?
How effects on health equity are assessed in systematic reviews of interventions
How frequently should inhaler technique assessment be performed for someone with asthma?
How is inhaler technique best assessed for someone with asthma?
How long should a course of antibiotic treatment be for acne?
How many doses of reliever can be given safely to a child showing signs of an impending asthma attack?
How many times can you use the same syringe to inject insulin?
How might acne relapses be best treated?
How much will treating psychological distress, including depression and anxiety in adults with psoriasis and psoriatic arthritis have an effect on disease severity and flare-ups?
How much alcohol is safe to consume while taking epilepsy medication?
How much do psychological interventions (such as counselling) help people with vitiligo?
How much does avoidance of irritants and allergens help people with eczema ?
How much does family and patient training help patients with dystrophic epidermolysis bullosa?
How much does hypnotherapy/biofeedback help patients with eczema?
How much does management in reference centers help patients with dystrophic epidermolysis bullosa?
How much does massage therapy help patients with eczema?
How much does supporting and educating (about treatments and management) patients/carers help in the treatment of eczema?
How much does temperature, weather and humidity effect people with eczema?
How much does water type (hard/soft/sea) help patients with eczema?
How much does whole body fish treatment help patients with eczema?
How much effect do normal clothing fabrics have on eczema?
How much is too much medication to use of the preventer medicine when breathing difficulty does not go away over several hours?
How much symptom relief occurs in women taking Pentoxifylline for the treatment of endometriosis?
How often should blood pressure be measured in healthy pregnant women and when is the best time to do this?
How reliable is first-trimester screening for Down’s syndrome incorporating levels of pregnancy associated plasma protein (PAPP-A) in women with pre-existing diabetes?
How safe is acupuncture for knee osteoarthritis?
How safe is it for my baby if I am breastfeeding and taking antidepressant medication?
How safe is pseudocatalase cream combined with UVB light therapy in treating vitiligo?
How safe is PUVA therapy in treating vitiligo?
How safe is skin grafting in treating vitiligo?
How safe is UVA light therapy in treating vitiligo?
How safe is UVB light therapy in treating vitiligo?
How satisfied are patients with schizophrenia with the drug they take for their illness
How should healthcare professionals balance the treatment needs of children with the involvement of parents?
How should I decide whether to nebulise again following an asthma attack, or go to hospital?
How should I manage my asthma when I have a cold?
How should I take my epilepsy medication when I have a stomach upset?
How should topical therapies be used to maintain disease control for people with psoriasis?
How should you manage your epilepsy medication in new time zones?
How successful is surgery for epilepsy?
How tightly controlled do fluctuations in blood glucose levels need to be to reduce the risk of developing complications in people with type 1 diabetes?
How to avoid fever after dressing changes in patients with dystrophic epidermolysis bullosa?
How to choose the best systemic antibiotic to treat cutaneous infection in patients with dystrophic epidermolysis bullosa?
How useful are silver impregnated clothes to prevent infection in patients with dystrophic epidermolysis bullosa?
How will Government / Clinical guidelines help my brittle asthma?
HTA study of antidepressants for depression in dementia - a definitive multicentre pragmatic randomised controlled trial of clinical and cost effectiveness (HTA-SADD)
Huangqi injection for patients with chronic heart failure
Human albumin infusion for treating oedema in people with nephrotic syndrome
Human chorionic gonadotrophin (hCG) for preventing miscarriage
Human growth hormone during the active phase of intestinal adaptation in short bowel syndrome
Human papillomavirus (HPV) vaccine for individuals with HIV infection
Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions
Human recombinant activated factor VII for upper gastrointestinal bleeding in patients with liver diseases
Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients
Humanistic therapies versus treatment as usual for depression
Humidification of inspired air in exercise-induced asthma
Huperzine A for mild cognitive impairment
Huperzine A for vascular dementia
Hyaluronate for temporomandibular joint disorders
Hyaluronidase for reducing perineal trauma
Hybrid Positron Emission Tomography/computerised Tomography vs Positron Emission Tomography in lung cancer
Hydralazine in infants with persistent hypoxemic respiratory failure
Hydralazine/isosorbide dinitrate for heart failure
Hydrocolloid dressings for healing diabetic foot ulcers
Hydrocolloid dressings for treating pressure ulcers
Hydrogel dressings for healing diabetic foot ulcers
Hydrotherapy for asthma
Hydroxyurea for psoriasis
Hydroxyzine for generalised anxiety disorder
Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa
Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus
Hyperbaric oxygen therapy (HBOT) for fracture healing
Hyperbaric oxygen therapy and eye disorders
Hyperbaric oxygen therapy and infertility
Hyperbaric oxygen therapy and sports injuries
Hyperbaric oxygen therapy and surgical site infection
Hyperbaric oxygen therapy and thermal burns
Hyperbaric oxygen therapy and urology
Hyperbaric oxygen therapy for acute coronary syndrome
Hyperbaric oxygen therapy for acute coronary syndrome
Hyperbaric oxygen therapy for Bell's palsy
Hyperbaric oxygen therapy for blunt chest injury
Hyperbaric oxygen therapy for calciphylaxis
Hyperbaric oxygen therapy for cancers and tumour sensitisation to radiotherapy
Hyperbaric oxygen therapy for cardio-pulmonary bypass
Hyperbaric oxygen therapy for chronic hepatitis
Hyperbaric oxygen therapy for chronic wounds
Hyperbaric oxygen therapy for Crohn's disease
Hyperbaric oxygen therapy for crush injuries
Hyperbaric oxygen therapy for late radiation tissue injury
Hyperbaric oxygen therapy for malignant otitis externa
Hyperbaric oxygen therapy for multiple sclerosis
Hyperbaric oxygen therapy for osteoarthritis
Hyperbaric oxygen therapy for osteonecrosis of the mandible
Hyperbaric oxygen therapy for osteoradionecrosis
Hyperbaric oxygen therapy for other chronic wounds
Hyperbaric oxygen therapy for pain syndromes
Hyperbaric oxygen therapy for peridontitis
Hyperbaric oxygen therapy for pressure ulcers
Hyperbaric oxygen therapy for promoting fracture healing and treating fracture non-union
Hyperbaric oxygen therapy for severe anaemia
Hyperbaric oxygen therapy for skin grafts and flaps
Hyperbaric oxygen therapy for soft-tissue radionecrosis
Hyperbaric oxygen therapy for surgery
Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury
Hyperbaric oxygen therapy for the treatment of livedoid vasculopathy
Hyperbaric oxygen therapy for traumatic brain injury
Hyperbaric oxygen therapy for treatment of necrotising soft-tissue infections
Hyperbaric oxygen therapy for vascular dementia
Hyperbaric oxygen therapy for venous ulcers
Hyperbaric oxygen therapy for wound healing
Hyperbaric oxygenation for tumour sensitisation to radiotherapy
Hyperbarix oxygen therapy for soft-tissue radionecrosis
Hyperfractionated or accelerated radiotherapy for head and neck cancer
Hypnosis during pregnancy, childbirth, and the postnatal period for preventing postnatal depression
Hypnosis for pain management during labour and childbirth
Hypnosis for people with asthma
Hypnosis for preventing preterm labour
Hypnotherapy and biofeedback therapy for atopic eczema
Hypnotherapy for Ménière's disease
Hypnotherapy for nocturnal enuresis
Hypoallergenic formula milk versus cow's milk for prevention of wheeze and asthma in children with a family history of atopy
Hypoglycaemic agents for pregnant women with polycystic ovarian syndrome
Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia
Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation
Hypothermia for neuroprotection in children after cardiopulmonary arrest
Hypothermia for traumatic head injury
Hypoventilation to decrease blood loss and blood transfusion requirements for liver resection
Hysterectomy for patients with locally advanced cervical cancer after primary radiotherapy and/or chemotherapy
Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities
I recently became very depressed when my asthma inhaler was changed to Symbicort and felt much better when I gave myself a break from this inhaler. Is there any evidence that different inhalers have different effects on mood?
I take ventolin 2 puffs QDS & becotide 200mgs 2 puffs QDS. I constantly have coughing fits sometimes leading to vomiting or nose bleeds and stress incontinence. Are these recognised side effects of these treatments?
Ibuprofen and paracetamol in combination and separately for fever in pre-school children presenting to primary care
Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants
Ibuprofen with or without an antiemetic for acute migraine headaches in adults
Idarubicin compared to other anthracyclines for treatment of newly diagnosed acute myeloid leukaemia
If a person benefiting from taking lithium for mood disorders stays on it, are adverse renal effects dose-related?
If doctors cannot diagnose asthma in children under 2, what is the most appropriate treatment?
If I avoid certain chemicals in the work place/environment, will I reduce my risk of developing prostate cancer?
If I can have my own choice of insulin, and how it is delivered, will my diabetes be better controlled?
If my child, who has asthma, is poorly but on medication, should I send him to school?
If toe nails are being cut round instead of straight, will this produce more ingrown nails?
Ileostomy or colostomy for temporary decompression of colorectal anastomosis
Image-guided percutaneous procedure plus metronidazole versus metronidazole alone for uncomplicated amoebic liver abscess
Image-guided versus blind glucocorticoid injection for shoulder pain
Imaging modalities for characterising focal pancreatic lesions
Imiquimod for anogenital warts in non-immunocompromised adults
Immediate loading with single implant crowns
Immediate restoration/loading of immediately placed single implants: is it an effective bimodal approach?
Immediate start of hormonal contraceptives for contraception
Immediate versus deferred delivery of the preterm baby with suspected fetal compromise for improving outcomes
Immediate versus delayed reconstruction following surgery for breast cancer
Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy
Immunomodulatory interventions for focal epilepsy syndromes
Immunonutrition in patients undergoing surgery for head and neck cancer
Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis
Immunosuppressant and immunomodulatory treatments for multifocal motor neuropathy
Immunosuppression in primary focal segmental glomerular sclerosis (FSGS) in adults
Immunosuppression in renal transplantation
Immunosuppressive drugs for Lyme disease
Immunosuppressive or biological therapy compared with early surgery for Crohn's disease limited to the distal ileum
Immunotherapy for diabetic amyotrophy
Immunotherapy for diabetic amyotrophy
Immunotherapy for IgM anti-myelin-associated glycoprotein paraprotein-associated peripheral neuropathies
Immunotherapy vs conventional asthma pharmacotherapy and allergen immunotherapy
Impact of haemophilus influenza type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes
Impact of preconception counselling on quality of life and satisfaction of care in women with epilepsy
Importance of correct point location in acupuncture for migraine prophylaxis
In a critically ill patient is dopexamine effective at preventing renal failure?
In adults greater than 18 years of age with suspected transient ischaemic attack is the administration of aspirin by paramedics in prehospital care safe in the absence of a brain scan?
In adults with stage 4 or 5 chronic kidney disease (CKD), including those on dialysis, what is the long-term effectiveness and safety of aluminium hydroxide in controlling serum phosphate?
In adults with stage 4 or 5 chronic kidney disease (CKD), including those on dialysis, what is the long-term effectiveness and safety of magnesium carbonate in controlling serum phosphate?
In an asthma emergency, what are the advantages and disadvantages of a nebuliser compared with filling up a spacer with multiple Ventolin squirts?
In cases of metastatic squamous cell carcinoma (SCC) in cervical lymph nodes with occult primary, in which circumstances is prophylactic wide field radiotherapy to potential primary sites beneficial in terms of loco-regional control and overall survival.
In cases of metastatic squamous cell carcinoma (SCC) in cervical lymph nodes with occult primary, is there any benefit in carrying out a PET/CT scan to locate the primary tumour?
In female patients complaining of loss of libido is there any evidence that hormone therapy (oestrogen or progestogen or androgen) is beneficial?
In individuals with cleft lip/palate what is the most effective speech therapy to eliminate cleft type speech characteristics?
In individuals with cleft lip/palate when is the most effective age to begin speech therapy?
In patients identified on primary examination as exhibiting possible COAG, OHT or glaucoma suspect status, what is the comparative effectiveness of diagnosis by different healthcare professions?
In patients with asthma on inhaled steroids are symptoms better controlled or side effects improved when taking steroid using a Metered Dose Inhaler (MDI) and spacer or breath activated device?
In patients with asthma on oral steroids, which drugs/intervention are needed/effective in preventing or treating hypertension?
In patients with asthma on oral steroids, which drugs/intervention are needed/effective in preventing or treating loss of growth in children?
In patients with Venous thromboembolism and active cancer who have had 6 months of anticoagulation treatment with low molecular weight heparin (LMWH), what is the clinical benefit (in terms of VTE recurrence rates, all-cause mortality and major bleeding) and cost effectiveness of continued anticoagulation treatment with LMWH versus a vitamin K antagonist (VKA)?
In people with chronic schizophrenia who have to stop clozapine, what is the most appropriate choice of antipsychotic in terms of symptom control and quality of life?
In people with neurogenic lower urinary tract dysfunction, which management strategies (including the use of prophylactic antibiotics and various invasive and non-invasive techniques to aid bladder drainage) reduce the risk of symptomatic urinary tract infections?
In the patient with severe asthma which deteriorates in pregnancy what is the best way to manage and monitor the condition?
In which circumstances is post operative radiotherapy to lymph node areas beneficial for Head and Neck cancer in terms of improving local control and overall survival?
Incentive spirometry for preventing pulmonary complications after coronary artery bypass graft
Incentive-based and non-incentive-based interventions for increasing blood donation
Incentives for increasing prenatal care use by women in order to improve maternal and neonatal outcomes
Incentives for preventing smoking in children and adolescents
Increased consumption of fruit and vegetables for the primary prevention of cardiovascular diseases
Increased sunscreen use to reduce incidences of skin cancer
Indacaterol, a once-daily beta2-agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease
Individual and group based parenting programmes for improving psychosocial outcomes for teenage parents and their children
Individual Cognitive Behavioural Therapy for children with depression
Individual interventions by breast cancer nurses' and the effact on quality of life outcomes for women with breast cancer
Individual-, family-, and school-level interventions for preventing multiple risk behaviours in individuals aged 8 to 25 years
Induction of labour for improving birth outcomes for women at or beyond term
Induction of labour for suspected fetal macrosomia
Indwelling bladder catheterization as part of postoperative care for caesarean section
Infant position in neonates receiving mechanical ventilation
Infection control strategies for preventing the transmission of meticillin-resistant Staphylococcus aureus (MRSA) in nursing homes for older people
Inferior turbinate surgery for nasal obstruction in allergic rhinitis after failed medical treatment
Inferior turbinate surgery for nasal obstruction in allergic rhinitis after failed medical treatment
Infliximab for induction of remission of ulcerative colitis
Influenza vaccines for preventing acute otitis media in infants and children
Information and communication technology in patient education and support for people with schizophrenia
Information and communication technology-based cognitive remediation for supporting treatment compliance for people with serious mental illness
Information giving to improve outcomes for Crohn's disease
Information interventions for orienting patients and their carers to cancer care facilities
Information provision for stroke patients and their caregivers
Informative value of clinical research on multislice computed tomography in the diagnosis of coronary artery disease
Infrared laser treatment for acne
Inhalation versus intravenous technique for rapid emergence from anaesthesia in patients undergoing brain tumour surgery
Inhaled analgesia for pain management in labour
Inhaled antibiotics for long-term therapy in cystic fibrosis
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis
Inhaled beta2-agonist and anticholinergic agents for emergency management of asthma in adults
Inhaled beta2-agonists for asthma in mechanically ventilated patients
Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease
Inhaled corticosteroid prophylaxis for exercise induced bronchoconstriction
Inhaled corticosteroids for cystic fibrosis
Inhaled corticosteroids for stable chronic obstructive pulmonary disease
Inhaled corticosteroids for subacute and chronic cough in adults, reduction in cough severity, complications of cough, inflammation and adverse effects
Inhaled corticosteroids for subacute cough in children
Inhaled corticosteroids in children with persistent asthma: dose-response effects on growth
Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth
Inhaled corticosteroids versus long-acting beta2-agonists for chronic obstructive pulmonary disease
Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma
Inhaled magnesium sulfate in the treatment of acute asthma
Inhaled nitric oxide for respiratory failure in preterm infants
Inhaled or nebulised corticosteroids for hospitalised children with acute asthma
Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease
Inhaled steroids for acute asthma following emergency department discharge
Inhaled versus systemic corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonates
Inhaled versus systemic corticosteroids for the treatment of chronic lung disease in ventilated very low birth weight preterm infants
Initial antithyroid drugs followed by thyroxine or no treatment for primary hyperthyroidism
Initial arch wires for tooth alignment during orthodontic treatment with fixed appliances
Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease
Injection of allergen-antibody complexes of house dust mites for atopic eczema
Injection therapy for subacute and acute low back pain
Inositol for respiratory distress syndrome in preterm infants
Inpatient admission versus day hospital for schizophrenia
Insoles for low back pain
Inspiratory muscle stength training vs endurance training in patients with COPD to improve maximal inspiratory pressure and functional exercise capacity
Inspiratory muscle training and physical training for reducing neuromuscular dysfunction in critically ill adults in intensive care units
Inspiratory muscle training for the recovery of function after stroke
Instruments for assessing readiness to commence suck feeds in preterm infants: effects on time to establish full oral feeding and duration of hospitalisation
Instruments for chorionic villus sampling for prenatal diagnosis
Insulin delivery methods, other than injection.
Insulin detemir versus insulin glargine for type 2 diabetes mellitus
Insulin for glycaemic control in acute ischaemic stroke
Insulin therapy for glycaemic control in critically ill children
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility
Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome
Integrated and non-integrated orbital implants for treating anophthalmic sockets
Integrated Management of Childhood Illness (IMCI) Strategy for children under five: effects on death, service utilisation and illness
Integration of HIV/AIDS services with maternal, neonatal and child health, nutrition, and family planning services
Intense pulsed light therapy for acne
Intensity-modulated versus conventional radiotherapy for breast cancer
Intensive Case Management for severe mental illness
Interactive computer-based interventions for sexual health promotion
Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people
Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes
Interdental brushing for the management of periodontal diseases and dental caries in adults
Interentions to develop the emotional and social skills of vulnerable, preschool children
Interferon Alpha Adjuvant Therapy in Patients with High-Risk Melanoma
Interferon alpha for chronic hepatitis D
Interferon alpha-2b and ribavirin maintenance therapy for halting hepatitis C disease progression in liver-transplanted patients
Interferon beta for primary progressive multiple sclerosis
Interferon for interferon nonresponding and relapsing patients with chronic hepatitis C
Interleukin-1 inhibitors for chronic gout
Interleukin-2 as maintenance therapy for children and adults with acute myeloid leukaemia in first complete remission
Intermittent catheterisation and indwelling catheters as first choice treatment for urinary incontinence
Intermittent drug techniques for schizophrenia
Intermittent drug techniques for schizophrenia
Intermittent iron supplementation for improving nutrition and development in children under 12 years of age
Intermittent iron supplementation for reducing anaemia and its associated impairments in menstruating women
Intermittent oral iron supplementation during pregnancy
Intermittent pneumatic compression for treating venous leg ulcers
Intermittent self-dilatation for urethral stricture disease in men
Intermittent versus continuous androgen suppression for prostatic cancer
Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
Internal fixation implants for intracapsular hip fractures in adults
Internal fixation versus arthroplasty for intracapsular proximal femoral fractures in adults
Internal versus external tocodynamometry during induced or augmented labour
Internet interventions for treatment of alcohol-related problems
Internet-based interventions for smoking cessation
Interobserver variation in the delineation of target volumes using positron emission tomography for non-small cell lung cancer patients with atelectasis
Interpersonal, cognitive analytic and other integrative therapies versus treatment as usual for depression
Interposition vein cuff for infragenicular prosthetic bypass graft
Interprofessional education: effects on professional practice and healthcare outcomes (update)
Interval debulking surgery for advanced epithelial ovarian cancer
Intervention for developmental apraxia of speech
Intervention for prostate cancer prevention approaches
Interventions before pregnancy to improve pregnancy outcomes for women with epilepsy and their offspring
Interventions designed to prevent healthcare bed-related injuries in patients
Interventions for actinic keratoses
Interventions for acute auricular haematoma
Interventions for acute internal hordeolum
Interventions for age-related visual problems in patients with stroke
Interventions for anal canal intraepithelial neoplasia
Interventions for apathy after traumatic brain injury
Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment
Interventions for atrophic rhinitis
Interventions for auditory processing disorder
Interventions for both male and female sexual dysfunction in chronic kidney disease
Interventions for bronchiectasis: an overview of Cochrane systematic reviews
Interventions for cachexia-anorexia syndrome in people with lung cancer
Interventions for caregivers for the recognition of disease-related complications in children with sickle cell disease
Interventions for chronic blepharitis
Interventions for congenital talipes equinovarus (clubfoot)
Interventions for cough in cancer
Interventions for covert bacteriuria in children
Interventions for disorders of eye movement in patients with stroke
Interventions for drooling in children with cerebral palsy
Interventions for dysphagia and nutritional support in acute and subacute stroke
Interventions for ear discharge associated with grommets (ventilation tubes)
Interventions for emergency contraception
Interventions for erosive lichen planus affecting mucosal sites
Interventions for erythrodermic psoriasis
Interventions for facial palsy associated with Lyme disease
Interventions for failure of the initial course of antibiotics for Lyme disease
Interventions for fatigue and weight loss in adults with advanced progressive illness
Interventions for female pattern hair loss
Interventions for Generalised Anxiety Disorder in older people with cognitive decline
Interventions for guttate psoriasis
Interventions for helping people recognise early signs of recurrence in depression
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version
Interventions for hidradenitis suppurativa
Interventions for hiring, retaining and training district health systems managers in low- and middle-income countries
Interventions for hirsutism excluding laser and photoepilation therapy
Interventions for HIV-associated nephropathy
Interventions for impetigo
Interventions for improving adherence to ocular hypotensive therapy
Interventions for improving adherence to ocular hypotensive therapy
Interventions for improving asthma care in ethnic minorities
Interventions for improving community ambulation in individuals with stroke
Interventions for improving coverage of child immunization in low- and middle-income countries
Interventions for improving mobility after hip fracture surgery in adults
Interventions for improving outcomes for pregnant women who have experienced genital cutting
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings
Interventions for improving palliative care for older people living in nursing care homes
Interventions for increasing fruit and vegetable consumption in children aged 5 years and under
Interventions for induction and maintenance of mucosal healing in Crohn's disease
Interventions for infantile esotropia
Interventions for infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for ingrowing toenails
Interventions for insomnia in conjunction with antipsychotic drug use
Interventions for intertriginous or flexural psoriasis
Interventions for involutional lower lid entropion
Interventions for late trabeculectomy bleb leak
Interventions for melanoma in situ, including lentigo maligna
Interventions for mycosis fungoides
Interventions for nail psoriasis
Interventions for nausea and vomiting in early pregnancy
Interventions for neovascular age-related macular degeneration
Interventions for neuropathic pain in Lyme disease
Interventions for non-oliguric hyperkalaemia in preterm neonates
Interventions for normal tension glaucoma
Interventions for obsessive compulsive symptoms in people with schizophrenia
Interventions for oropharyngeal dysphagia in children with neurological impairment
Interventions for Paget’s disease of the vulva
Interventions for periodontal disease in people with rheumatoid arthritis
Interventions for post-transplant anaemia in kidney transplant recipients
Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteria
Interventions for preventing abuse in the elderly
Interventions for preventing and reducing the use of physical restraints in long-term geriatric care
Interventions for preventing and treating hyperthyroidism in pregnancy
Interventions for preventing and treating squamous cell carcinoma of the conjunctiva in HIV-infected individuals
Interventions for preventing delirium in hospitalised patients
Interventions for preventing excessive weight gain during pregnancy
Interventions for preventing falls in older people in care facilities and hospitals
Interventions for preventing falls in older people living in the community
Interventions for preventing falls in older people living in the community
Interventions for preventing infection in nephrotic syndrome
Interventions for preventing intensive care unit delirium
Interventions for preventing mastitis after childbirth
Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section
Interventions for preventing neuropathy caused by cisplatin and related compounds
Interventions for preventing non-melanoma skin cancers in high risks groups?
Interventions for preventing or reducing domestic violence against pregnant women
Interventions for preventing oral mucositis for patients with cancer receiving treatment
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery
Interventions for preventing recurrent urinary tract infection during pregnancy
Interventions for preventing relapse and recurrence after the first episode of a depressive disorder in young people
Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents
Interventions for preventing the progression of autosomal dominant polycystic kidney disease
Interventions for preventing weight gain after smoking cessation
Interventions for prevention and treatment of vulvovaginal candidiasis in women with HIV infection
Interventions for prevention of giant retinal tear in the fellow eye
Interventions for prevention of herpes simplex labialis (cold sores on the lips)
Interventions for primary (intrinsic) tracheomalacia in children
Interventions for primary prevention of occupational asthma
Interventions for promoting habitual exercise in people living with and beyond cancer
Interventions for providers to promote a patient-centred approach in clinical consultations
Interventions for psoriasis in children
Interventions for psoriasis in obese people
Interventions for psoriasis in people with hepatitis C
Interventions for psoriasis in people with HIV infection
Interventions for psychiatric symptoms associated with Lyme disease
Interventions for psychosis in adolescents
Interventions for psychotic symptoms concomitant with epilepsy
Interventions for recruiting smokers into cessation programmes
Interventions for recurrent corneal erosions
Interventions for recurrent idiopathic epistaxis (nosebleeds) in children
Interventions for recurrent idiopathic epistaxis (nosebleeds) in children
Interventions for reducing anxiety in women undergoing colposcopy
Interventions for reducing itch in atopic eczema
Interventions for reducing medication errors in hospitalised adults
Interventions for reducing wrong-site surgery and invasive procedures
Interventions for relapse in Lyme disease following completion of treatment regimen
Interventions for replacing missing teeth: alveolar ridge preservation techniques for oral implant site development
Interventions for replacing missing teeth: different times for loading dental implants
Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants
Interventions for replacing missing teeth: management of soft tissues for dental implants
Interventions for replacing missing teeth: partially absent dentition
Interventions for replacing missing teeth: treatment of peri-implantitis
Interventions for restoring patency of occluded central venous catheter lumens
Interventions for rosacea
Interventions for segmental vitiligo
Interventions for severe scalp psoriasis
Interventions for sexual dysfunction following treatments for cancer – excluding PDE5 inhibitors
Interventions for smokeless tobacco use cessation
Interventions for smoking cessation and reduction in individuals with schizophrenia
Interventions for smoking cessation in hospitalised patients
Interventions for smoking cessation in Indigenous populations
Interventions for squamous cell carcinoma of the conjunctiva in HIV-infected individuals
Interventions for stimulus deprivation amblyopia
Interventions for strabismic amblyopia
Interventions for supporting parents' decisions about autopsy after stillbirth
Interventions for supporting women with decisions about mode of birth in a pregnancy after caesarean birth
Interventions for the eradication of methicillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis
Interventions for the management of dry mouth: topical therapies
Interventions for the management of oral submucous fibrosis
Interventions for the management of taste disturbances
Interventions for the management of temporomandibular joint osteoarthritis
Interventions for the prevention of mycobacterium avium complex in adults and children with HIV
Interventions for the prevention of postoperative atrial fibrillation in adult patients undergoing noncardiac thoracic surgery
Interventions for the prevention of postoperative ear discharge after insertion of ventilation tubes (grommets) in children
Interventions for the reduction of prescribed opioid use in chronic non-cancer pain
Interventions for the symptoms and signs resulting from jellyfish stings
Interventions for the treatment of Frey's syndrome
Interventions for the treatment of keratocystic odontogenic tumours (KCOT, odontogenic keratocysts (OKC))
Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment
Interventions for the treatment of oral and oropharyngeal cancers: targeted therapy and immunotherapy
Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy
Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy
Interventions for tobacco cessation in the dental setting
Interventions for tobacco use cessation in people in treatment for or recovery from substance abuse
Interventions for tobacco use prevention in Indigenous youth
Interventions for tophi in gout
Interventions for treating acute elbow dislocations in adults
Interventions for treating AIDS-associated Hodgkin acute lymphoma in treatment-naive adults
Interventions for treating anxiety after stroke
Interventions for treating chronic ankle instability
Interventions for treating genital Chlamydia trachomatis infection in pregnancy
Interventions for treating inadvertent postoperative hypothermia
Interventions for treating isolated diaphyseal fractures of the ulna in adults
Interventions for treating leg ulcers in people with sickle cell disease
Interventions for treating oral candidiasis for patients with cancer receiving treatment
Interventions for treating oral leukoplakia
Interventions for treating oral mucositis for patients with cancer receiving treatment
Interventions for treating osteoarthritis of the big toe joint
Interventions for treating pain and disability in adults with complex regional pain syndrome
Interventions for treating peripartum cardiomyopathy to improve outcomes for women and babies
Interventions for treating persistent and intractable hiccups in adults
Interventions for treating phosphorus burns
Interventions for treating placental abruption
Interventions for treating postpartum constipation
Interventions for treating proximal humeral fractures in adults
Interventions for treating sexual dysfunction in patients with chronic kidney disease
Interventions for treating slipped upper femoral epiphysis (SUFE)
Interventions for treating supracondylar fractures of the humerus in children
Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth
Interventions for treatment of chronic hepatitis B in lamivudine-resistant patients
Interventions for unilateral and bilateral refractive amblyopia
Interventions for unilateral refractive amblyopia
Interventions for vaginismus
Interventions for visual field defects in patients with stroke
Interventions for vitiligo in children
Interventions for women in subsequent pregnancies following obstetric anal sphincter injury for improving health
Interventions in the workplace to support breastfeeding for women in employment
Interventions other than anticoagulants and systemic antibiotics for prevention of central venous catheter-related infections in children with cancer
Interventions to aid staying at or returning to work during or following Lyme disease
Interventions to correct chronic metabolic acidosis in patients with chronic kidney disease
Interventions to enhance adherence to dietary advice for preventing and managing chronic diseases in adults
Interventions to enhance return-to-work for cancer patients
Interventions to facilitate return to work in adults with adjustment disorders
Interventions to improve adherence to antiretroviral therapy in children with HIV infection
Interventions to improve antibiotic prescribing practices for hospital inpatients
Interventions to improve attitudes towards treatment and treatment compliance among adolescents with attention deficit-hyperactivity disorder (ADHD)
Interventions to improve compliance with treatment in schizophrenia
Interventions to improve continuity of care in the follow-up of patients with cancer
Interventions to improve hearing aid use in adult auditory rehabilitation
Interventions to improve occupational health in depressed people
Interventions to improve professional adherence to guidelines for prevention of device-related infections
Interventions to improve the appropriate use of polypharmacy for older people
Interventions to improve the use of systematic reviews in decision-making by health system managers, policy makers and clinicians
Interventions to improve vaginal health for reducing the risk of HIV acquisition
Interventions to increase clinical incident reporting in health care
Interventions to increase influenza vaccination rates of those 60 years and older in the community
Interventions to increase the reporting of occupational diseases by physicians
Interventions to manage dual practice among health workers
Interventions to optimise prescribing for older people in care homes
Interventions to prevent injuries in construction workers
Interventions to prevent occupational noise-induced hearing loss
Interventions to prevent or manage obesity in children and adults in the UK
Interventions to prevent or manage obesity in different population groups
Interventions to prevent sleep disruption in infants with atopic eczema
Interventions to promote the wearing of hearing protection
Interventions to reduce experiences of stigma and discrimination of people with mental illness and their caregivers
Interventions to reduce or relieve the pain and discomfort of screening mammography
Interventions to reduce risky sexual behaviour for preventing HIV infection in workers in occupational settings
Interventions to reduce Staphylococcus aureus in the management of atopic eczema
Interventions to reduce weight gain in schizophrenia
Interventions to slow progression of myopia in children
Interventions when Lyme disease symptoms are failing to respond during treatment
Interventions with families of alcohol misusers
Intestinal dysfunction and QOL in patients with or without radiotherapy after rectal cancer resection
Inteventions to achieve continuity of care for prisoners who are diagnosed with chronic hepatitis B or C in prison?
Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock
Intra-articular analgesia for anterior cruciate ligament reconstruction
Intra-articular glucocorticoids for acute gout
Intra-articular glucocorticoids for acute gout
Intra-articular hyaluronate for rheumatoid arthritis
Intra-articular lignocaine versus intravenous analgesia with or without sedation for manual reduction of acute anterior shoulder dislocation in adults
Intracutaneous or subcutaneous sterile water injection compared with blinded controls for pain management in labour
Intracystic bleomycin for cystic craniopharyngiomas in children
Intramedullary nailing for tibial shaft fractures in adults
Intramedullary nails for extracapsular hip fractures in adults
Intramural urethral bulking procedures for stress urinary incontinence in women
Intramuscular versus intravenous anti-D for preventing Rhesus alloimmunization during pregnancy
Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour
Intranasal fentanyl for the management of acute pain in children
Intranasal ipratropium bromide for the common cold
Intranasal ipratropium bromide with placebo for seasonal allergic rhinitis
Intranasal or transdermal nicotine for the treatment of postoperative pain
Intranasal steroids for acute sinusitis
Intraoperative 5-Fluorouracil for glaucoma surgery
Intra-operative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses
Intra-operative imaging for neuro-oncology
Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents
Intraoperative mild hypothermia for postoperative neurological deficits in intracranial aneurysm patients
Intra-operative Mitomycin C for glaucoma surgery
Intraopetarive Radiotherapy for Solid Tumours
Intrapartum antibiotics for known maternal Group B streptococcal colonization
Intraperitoneal carboplatin versus cisplatin for primary epithelial ovarian cancer
Intratracheal Clara cell secretory protein (CCSP) administration in preterm infants with or at risk of respiratory distress syndrome
Intratympanic gentamicin for Meniere's disease or syndrome
Intratympanic gentamicin in Ménière's disease
Intratympanic steroids for Ménière's disease and sudden sensorineural hearing loss
Intratympanic steroids for Ménière's disease or syndrome
Intra-uterine insemination for unexplained subfertility
Intra-vascular spread of Prostate Cancer by retorgrade saline 'transfusion' through the cut surface of the prostate during transurethral resection of the prostate (TURP)
Intravenous antibiotic therapy vs oral antibiotic therapy within the first 24 hours of treatment in patients with neutropenic sepsis who are having treatment with intravenous antibiotics
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
Intravenous beta2-agonists versus intravenous aminophylline for acute asthma
Intravenous cetraxone for late Lyme disease
Intra-venous fluids for the prevention of severe ovarian hyperstimulation syndrome
Intravenous immunoglobulin as a corticosteroid sparing agent for chronic asthma
Intravenous immunoglobulin as adjuvant therapy for Wegener's granulomatosis
Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy
Intravenous immunoglobulin for Guillain-Barr? syndrome
Intravenous immunoglobulin for myasthenia gravis
Intravenous immunoglobulin for suspected or subsequently proven infection in neonates
Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock
Intravenous inotropic drugs in acute heart failure
Intravenous lidocaine for the treatment of background or procedural burn pain
Intravenous magnesium sulphate for acute severe asthma
Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit
Intravenous naftidrofuryl for critical limb ischaemia
Intravenous nitrates or intravenous furosemide for acute heart failure
Intravenous polyclonal human immunoglobins for relapse-remitting multiple sclerosis
Intravenous secretin for autism spectrum disorders (ASD)
Intravenous versus inhalation anaesthesia for patients undergoing on-pump or off-pump coronary artery bypass grafting
Intravenous versus oral antibiotic treatment for Lyme disease
Intraventricular antibiotics for bacterial meningitis in neonates
Intravesical Bacillus Calmette-Gu?rin versus epirubicin for Ta and T1 bladder cancer
Intravesical Bacillus Calmette-Guerin versus epirubicin for Ta and T1 bladder cancer
Intravesical gemcitabine for non-muscle invasive bladder cancer
Intravitreal bevacizumab (Avastin) vs. ranibizumab (Lucentis) for the treatment of age-related macular degeneration
Intravitreal corticosteroids to improve visual acuity in branch retinal vein occlusion
Intravitreal corticosteroids to improve visual acuity in central retinal vein occlusion
Intravitreal injection of Triamcinolone for diabetic retinopathy
Intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors for diabetic retinopathy
Intravitreal low molecular weight heparin and 5-Fluorouracil for the prevention of proliferative vitreoretinopathy following retinal reattachment surgery
Intravitreal steroids versus observation for macular edema secondary to central retinal vein occlusion
In-vitro screening to test whether ataluren (PTC124) can correct functional consequences of premature termination mutations of the Flavin containing monooxygenase 3 (FMO3) gene?
Iodine solution for the prevention of chemotherapy-induced oral mucositis
Iodine-131-meta-iodobenzylguanidine therapy for patients with high-risk neuroblastoma
Iodised salt for preventing iodine deficiency disorders
Ionisers for chronic asthma
IQCODE for the diagnosis of Alzheimer's disease dementia and other dementias within a community setting
Iridectomy or iridotomy for preventing angle-closure glaucoma
Iron chelators for acute stroke
Iron for restless legs syndrome
Irrigants for non-surgical root canal treatment in mature permanent teeth
Is 6 months of trastuzumab treatment sufficient when compared with 12 months?
Is a bath or shower more effective in improving healing and decrease infections for patients with dystrophic epidermolysis bullosa?
Is a combination of LH-RH analogue and oestrogen a valid treatment for advanced prostate cancer?
Is a Digital Rectal Examination safe if performed shortly after biopsy for prostate cancer?
Is acupuncture effective for peripheral joint osteoarthritis?
Is adjuvant chemotherapy effective in patients with aggressive prostate cancer?
Is amitriptyline a clinically and cost effective prophylactic treatment for recurrent migraine?
Is an artificial pancreas for type 1 diabetes (closed loop system) effective?
Is antidepressant medication safe for the foetus and mother if taken during pregnancy?
Is any specific surgical intervention effective in Ménière's disease and what procedure is best?
Is ascorbic acid effective in managing anaemia in haemodialysis patients?
Is Atrovent for asthma less likely to cause giddiness, nausea, shaking, headache and palpitations than salbutamol or Ventolin?
Is bibliotherapy effective for relieving psychotic symptoms?
Is bortezomib an effective therapy for Post Transplant Lymphoproliferative Disorders?
Is carbogen gas effective in the treatment of sudden sensorineural hearing loss?
Is Clozapine particularly effective in reducing hostility, violence and reducing suicide rates in schizophrenia?
Is Cognitive Behaviour Therapy/psychological therapy, delivered by audiology professionals, effective for people with tinnitus?
Is Cognitive Behavioural Therapy equally effective for all psychiatric conditions?
Is Cognitive Behavioural Therapy equally useful in patients with and without active medication?
Is combining or alternating antipyretic therapy more beneficial than monotherapy for febrile children?
Is continuous medication beneficial for my asthma if I don't have symptoms?
Is counselling adequate for schizophrenia?
Is DAFNE an effective patient education system for people with diabetes?
Is daily use of a Becotide inhaler necessary for asthma in children?
Is desmopressin effective in reducing nocturia and enuresis in elderly men?
Is desmopressin used for urinary incontinence safe and effective in patients over 60?
Is dietary and lifestyle advice effective in the treatment of overactive bladder?
Is Disease Management more effective than good quality usual care for heart failure?
Is drug therapy more effective than psychotherapy in treating emotional distress?
Is early switching of opioid, on development of side effects, more effective at reducing central side effects than persisting with current opioid and dose reduction in patients starting strong opioids?
Is ECT advised to treat mood disorders in people with schizophrenia?
Is ECT more effective and/or safer for the foetus, in severe depressive states, during the perinatal period than antidepressant medication?
Is ECT over the long term effective in treating schizophrenia?
Is external beam radiotherapy effective for treating prostate cancer?
Is finasteride effective in reducing nocturia in benign prostatic hyperplasia?
Is fish oil effective at reducing nephrotoxicity in kidney transplant recipients?
Is growth hormone treatment effective for children with chronic kidney disease?
Is hand and feet numbness associated with use of certain antiepileptic drugs?
Is homeopathic medication useful for asthma?
Is imiquimod useful to treat tumours in patients with dystrophic epidermolysis bullosa?
Is injected medication preferable to preventer inhalers for children with asthma?
Is insulin pump therapy effective? (immediate v deferred pump, and comparing outcomes with multiple injections)
Is it better to inhale steroids for my asthma rather than take them as tablets?
Is it better to use dental implants or bridges in patients with dystrophic epidermolysis bullosa?
Is it helpful for patients with balance disorders to adopt a specific diet?
Is it helpful for patients with balance disorders to reduce/avoid salt intake?
Is it helpful in preventing the severity, frequency and progression of attacks of Ménière's disease to adopt a specific diet, or restrict salt, caffeine or fluid intake?
Is it necessary to take the preventive inhaler everyday?
Is it possible to constantly and accurately monitor blood sugar levels, in people with type 1 diabetes, with a discrete device (microchip, implant for example) ?
Is it possible to step-down to lower dose, combination inhalers, such as Seretide or Symbicort for people with asthma?
Is it really necessary to take preventative medication if I only have mild asthma?
Is it safe to breastfeed on certain anti-epileptic drugs?
Is it safe to have a full body massage following Myocardial Infarction?
Is it safe to use steroids in children under two with asthma? What are the side effects and will I damage my child in the long term?
Is it true that atmospheric pressure/weather influences balance disorders, and how might this best be managed?
Is laser or diathermy ablation of endometriosis more likely to result in pregnancy in patients with subfertility?
Is laser therapy or other light therapies effective for a 40-year-old woman with rosacea on the face, who also had prior metranidazole cream and tetracycline with no success?
Is long term use of moisturizers on erosions associated with adverse events from treatments for dystrophic epidermolysis bullosa?
Is Ménière's disease triggered or exacerbated by any specific medication (and my implication is avoidance of those drugs helpful)?
Is metformin combined with insulin treatment in children and young people with type 1 diabetes better than treatment with insulin alone?
Is monochloroacetic acid more effective for the treatment of warts than liquid nitrogen?
Is MRI suitable to use for monitoring prostate cancer as part of an Active Surveillance programme?
Is neurostimulation effective in managing a neurogenic bladder?
Is olanzapine dangerous in patients with hyperglycaemia?
Is once daily insulin effective in treating children and young people with type 1 diabetes?
Is once daily insulin injection regime in children and young people with type 1 diabetes, especially in pre-school children, as effective as more complicated regimens?
Is one type of splint superior to another for osteoarthritis of the carpometacarpal joint?
Is physical therapy (electro-acupuncture, TENS and low level laser therapy) effective for osteoarthritic knee pain?
Is physiotherapy helpful for controlling asthma?
Is Pranayam Yoga helpful in asthma?
Is procyclidine effective in treating tardive dyskinesia if taken in conjunction with antipsychotics?
Is prophylactic prescription of anti-emetic treatment or availability of anti-emetic treatment at the patient's home more effective in reducing nausea than the availability of prescription on request for patients starting strong opioids for the treatment of pain in advanced or progressive disease?
Is protein Z influenced by the acute phase response?
Is pseudocatalase cream combined with brief exposure to UVB light as recommended, effective in treating vitiligo?
Is PUVA therapy more effective if used to treat vitiligo when it first appears, rather than waiting until the disease has spread?
Is recombinant human growth hormone (rhGH) therapy effective to improve cardiovascular effects in patients with congestive heart failure caused by left ventricular systolic dysfunction?
Is regulation of body temperature affected by use of antiepileptic drugs?
Is risperidone less likely than other antipsychotic drugs to cause tardive dyskinesia?
Is rituximab therapy associated with a higher rate of relapse in kidney transplant patients with post-transplant lymphoproliferative disorder?
Is selective or routine stenting in renal transplantation effective?
Is surgery more effective than wound care in the treatment of difficult to heal lesions in dystrophic epidermolysis bullosa?
Is Symbicort less likely to cause mucus formation than Advair in asthma?
Is systematic banking of colostrum antenatally of any benefit in pregnancies complicated by diabetes?
Is tension free vaginal tape surgery in women with mixed incontinence associated with better outcomes than maximal conservative treatments in terms of continence and quality of life?
Is the Buteyko breathing method useful for helping me control my asthma symptoms?
Is the effect of antipsychotic medication altered by illicit drug use or excessive alcohol consumption?
Is the treatment of ovarian endometriomas by coagulation, vapourisation, excision or cystectomy associated with a significant increase in cyst recurrence?
Is the use of antispychotic drugs in eldely patients more dangerous?
Is the use of Direct Renin Inhibitors complementary to or better than ACE/ARB in diabetic and also in non-diabetic nephropathy?
Is the use of insulin analogues associated with an increase in cancer rates?
Is there a bacteria responsible for producing trimethylamine (TMA) in the gut?
Is there a causative association between oral isotretinoin and depression and suicidal behaviour in acne patients?
Is there a curative treatment for prostate cancer that does not destroy a man's fertility and sex life?
Is there a difference in efficacy and acceptability of three currently available topical treatments in terms of clearance of pre-cancerous actinic keratoses (AK) and persistence of clearance of AK over 1 year?
Is there a difference in quality of life between those who use basal bolus or twice daily mixed insulin regimens?
Is there a genetic marker for prostate cancer that would be both more sensitive and more specific than PSA serum level?
Is there a genetic marker for prostate cancer that would be both more sensitive and more specific than PSA serum level?
Is there a monitoring regime that will give earlier indication of the requirement /need for follow up further treatment for prostate cancer?
Is there a more accurate test than the serum B12 test for monitoring pernicious anaemia, such as monitoring B12 analogues (that which the body cannot use)?
Is there a more reliable way of distinguishing benign prostate diseases from prostate cancer to improve outcomes for those diagnosed with prostate cancer?
Is there a role for polypharmacy with B12 for treating pernicious anaemia?
Is there a role for statins in atrial fibrillation?
Is there a treatment for prostate cancer that will be effective to the end of a man's normal life span?
Is there a vaccine that can prevent prostate cancer?
Is there a vaccine that can prevent prostate cancer?
Is there a way of preventing or delaying the spread of prostate cancer outside prostate gland?
Is there an effective drug to treat akathisia as a side effect of long term antipsychotic medication?
Is there an increase in the number of younger men developing aggressive prostate cancer? If so, does it affect treatment outcomes?
Is there any benefit for people with Type 1 diabetes from the addition of metformin to insulin treatment?
Is there any difference in the effects of PowerBreath and Buteyko breathing exercises in controlling asthma?
Is there any evidence for combination inhalers, e.g. Symbicort for people with asthma?
Is there any evidence for the use of metronidazole gel in the treatment of fungating breast cancer? Also can it be used in conjunction with actisorb silver to reduce bacterial load?
Is there any evidence of a better cure rate for treating proven fungal toe nail infections with both oral and topical preparations?
Is there any evidence that individualising treatment for prostate cancer has benefits?
Is there any evidence that prolonged use of inhaled steroids in asthma (e.g. fluticasone) causes an increased susceptibility to upper or lower respiratory tract infections?
Is there any evidence that supports consensus language/approaches within the people/health professionals educating for the care of people with asthma?
Is there any evidence to support giving the influenza vaccine to children with asthma?
Is there any evidence to support the use of silver dressing products?
Is there any information about the use of oestrogen (patches or oral forms) for the treatment of flushing in elderly men?
Is there any information on the role of postal or telephone communication in the management of asthma?
Is there any specific treatment to prevent drop attacks in patients with Ménière's disease?
Is there any value in treatments such as Deep Brain Stimulation (DBS) or psychosurgery for people with severe mental illness?
Is there evidence that any type of insulin is superior to purified pork insulin?
Is there evidence that men with prostate cancer and low PSA serum levels at diagnosis have worse outcomes?
Is there evidence that Seretide causes chest pain, foot muscle pains, insomnia, hoarseness and stomach bloating/pains?
Is there likely to be a new test for prostate cancer that will improve outcomes for those diagnosed?
Is thromboprophylaxis in patients in the ICU setting effective?
Is treatment with Light Emitting Diodes (LED), and other new technologies for phototherapy be beneficial for adults with psoriasis and psoriatic arthritis?
Is urethral dilation effective in treating urge incontinence in multiple sclerosis?
Is urinary diversion surgery more effective than indwelling catheterisation (urethral or suprapubic) for the management of a neurogenic bladder in patients with spina bifida?
Is urinary diversion surgery more effective than indwelling catheterisation (urethral or suprapubic) for the management of a neurogenic bladder in patients with spina bifida?
Is urodynamic testing prior to treatment decisions for mixed urinary incontinence associated with better continence rates and quality of life than treatment indicated by history, examination, free uroflowmetry, stress test and bladder diary?
Is UVB light therapy more effective in treating vitiligo when it first appears, rather than waiting until the disease has spread?
Is vitamin D3 an effective therapy for irritable bowel syndrome?
Is Xolair (omalizumab) an effective asthma medication for people with low IGE?
Ischaemic pre-conditioning for elective liver resections performed under vascular occlusion
Isoprinosine versus other antiviral drugs for chronic hepatitis B
Ivermectin versus benzimidazoles for treating strongyloides infection
Janus kinase-1 and Janus kinase-2 inhibitors for treating myelofibrosis
Kangaroo mother care to reduce morbidity and mortality in low birthweight infants
Ketamine as an adjuvant to opioids for cancer pain
Ketamine for management of acute exacerbations of asthma in children
Ketogenic diet and other dietary treatments for epilepsy
Knee length versus thigh length graduated compression stockings for prevention of deep vein thrombosis in postoperative surgical patients
Laceback ligatures for controlling anchorage in patients undergoing fixed orthodontic treatment
L-acetylcarnitine for fragile X syndrome
Lacosamide for neuropathic pain and fibromyalgia in adults
Lactase treated feeds to promote growth and feeding tolerance in preterm infants
Lactobacilli for maintenance of remission for Crohn's disease in children
Lamivudine or adefovir dipivoxil alone or combined with immunoglobulin for preventing hepatitis B recurrence after liver transplantation
Lamivudine versus lamivudine and thymosin alpha-1 for e antigen-positive chronic hepatitis B
Lamivudine with or without adefovir dipivoxil for postoperative hepatocellular carcinoma
Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures
Lamotrigine for acute and chronic pain
Language skills development for those with English as a second language against using interpreters for those with schizophrenia
Lanzhou Lamb rotavirus vaccine versus placebo for the prevention of rotavirus diarrhoea
Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome
Laparoscopic entry techniques
Laparoscopic gastric plication for severe obesity
Laparoscopic insertion of a magnetic bead band for gastro-oesophageal reflux disease (GORD)
Laparoscopic repair for perforated peptic ulcer disease
Laparoscopic surgery for pelvic pain associated with endometriosis
Laparoscopic surgery for presumed benign ovarian tumor during pregnancy
Laparoscopic surgery for ulcerative colitis
Laparoscopic surgical box model training for surgical trainees with limited prior laparoscopic experience
Laparoscopic surgical box model training for surgical trainees with no prior laparoscopic experience
Laparoscopic techniques for treating pelvic pain associated with endometriosis
Laparoscopic versus open distal gastectomy for gastric cancer
Laparoscopic versus open liver resection for benign and malignant hepatic lesions in adults
Laparoscopic versus open nephrectomy for live kidney donors
Laparoscopic versus open surgery for colon cancer in elderly patients with comorbidities
Laparoscopic versus open surgery for colon cancer in obese patients
Laparoscopic versus open surgery for colon cancer in patients with tumours in the left flexure
Laparoscopic versus open surgery for colon cancer in patients with tumours in the transverse colon
Laparoscopic versus open surgery for rectal cancer
Laparoscopic versus open surgery in small bowel obstruction
Laparoscopic versus open surgical techniques for ventral or incisional hernia repair
Laparoscopic-endoscopic rendezvous versus preoperative endoscopic sphincterotomy for common bile duct stones in patients undergoing laparoscopic cholecystectomy
Laparoscopy versus laparotomy for FIGO stage I ovarian cancer
Laparoscopy versus laparotomy for the management of early stage endometrial cancer
Lapatinib for metastatic breast cancer overexpressing HER2
Laquinimod for multiple sclerosis
Larval (maggots) therapy effective in the treatment of infected diabetic foot ulcers
Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants with or at risk of respiratory distress syndrome
Laryngeal mask airway versus endotracheal tube for percutaneous dilatational tracheostomy in critically ill patients
Laser peripheral iridoplasty for angle-closure
Laser peripheral iridoplasty for angle-closure
Laser resurfacing for treating facial acne scars
Laser trabeculoplasty for open angle glaucoma
Laser trabeculoplasty plus topical medical treatment for open angle glaucoma
Laser treatments versus conventional, drug therapies for acne
Laser-assisted in-situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia
Lasers for caries removal in deciduous and permanent teeth
Lasers or light sources for treating port-wine stains
Late (>7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants
Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants
Leflunomide for psoriasis
Lenalidomide for patients with red blood cell transfusion-dependent low- or intermediate-1-risk IPSS myelodysplastic syndromes
Length of duration of improvements associated with acupuncture treatment for migraine
Length of treatment time for patients with pure sleep-related epilepsy
Lens extraction for chronic angle-closure glaucoma
Less than a month versus several months' initial antibiotic treatment for Lyme disease
Leucotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Leucotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion
Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Leukotriene receptor antagonists in primary care at steps two and three of the national asthma guidelines
Leukotriene receptor antagonists in the treatment of nasal polyps
Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review
Levodopa for the treatment of restless legs syndrome
Levomepromazine for nausea and vomiting in palliative care
Levomepromazine for schizophrenia
Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery
Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery
Levosimendin in acute heart failure
Life skills programmes for chronic mental illnesses
Lifestyle changes in women with polycystic ovary syndrome
Lifestyle factors in the prevalence and severity of urinary incontinence and overactive bladder.
Lifestyle intervention for improving school achievement in overweight or obese children and adolescents
Lifestyle intervention on the treatment of urinary incontinence
Lifestyle interventions for chronic gout
Lifestyle interventions for the treatment of urinary incontinence in adults
Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates
Limited (regional) fasciectomy for Dupuytren’s contractures of the hand
Lipid lowering efficacy of atorvastatin
Lipid lowering efficacy of rosuvastatin
Liposomal antibiotics for Lyme disease
Liquid and fluid agents for preventing adhesions after surgery for subfertility
Listening to music for improving sleep in adults with insomnia
Lithium augmentation for depression
Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity
Local anaesthetic nerve block for pain management in labour
Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery
Local antibiotic and antiseptic prophylaxis in cardiac implantable electronic device implantation
Local cooling for relieving pain from perineal trauma sustained during childbirth
Local corticosteroid injections for arthritic pain
Local interventions for the management of alveolar osteitis (dry socket)
Local intramuscular transplantation of autologous mononuclear cells for critical lower limb ischaemia
Local opinion leaders: effects on professional practice and health care outcomes
Local versus general anaesthesia for patients undergoing pars plana vitrectomy surgery
Locomotor training for walking after spinal cord injury
Long term adverse effects of antipsychotic medication
Long term adverse effects of antipsychotic medication
Long term adverse effects of clozapine
Long term adverse effects of clozapine (Clozaril)
Long term benefit of adult aural rehabilitation programs
Long term benefit of the Epley manoeuvre for benign paroxysmal positional vertigo
Long term consequences of short term hormonal therapy for endometriosis-associated pain
Long term effectiveness of middle ear implants for hearing impairment
Long term effects of antipsychotic drugs on kidneys.
Long term effects of bilateral cochlear implants for profound deafness
Long term effects of cognitive behavioural therapy for tinnitus
Long term effects of glucocorticoid therapy for rheumatoid arthritis
Long term effects of grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children
Long term effects of grommets (ventilation tubes) for recurrent acute otitis media in children
Long term effects of pharmacological and non-pharmacological treatment for childhood attention deficit-hyperactivity disorder (ADHD)
Long term hormone therapy for perimenopausal and postmenopausal women
Long term outcomes for ultrasound-guided foam sclerotherapy for varicose veins
Long term outcomes of cochlear implantation in the first year of life
Long term outcomes of laparoscopic surgery for cancer of the upper rectum
Long term results of antiviral treatment for chronic hepatitis B
Long term results of medical versus surgical management for gastro-oesophageal reflux disease in adults
Long term safety of Omalizumab in the treatment of allergic rhinitis
Long term side effects of amisulpride for schizophrenia
Long term side effects of antipsychotics
Long versus short course treatment with metformin and clomiphene citrate for ovulation induction in women with PCOS
Long-acting beta2-agonist in addition to tiotropium versus either tiotropium or long-acting beta2-agonist alone for chronic obstructive pulmonary disease
Long-acting beta2-agonists for chronic obstructive pulmonary disease
Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma
Long-acting FSH versus daily FSH for women undergoing assisted reproduction
Long-acting therapy for chronic obstructive pulmonary disease: an overview
Longchain polyunsaturated fatty acid supplementation in infants born at term
Longchain polyunsaturated fatty acid supplementation in preterm infants
Long-term antibiotic treatment for Crohn's disease
Long-term antibiotic treatment for Lyme disease
Long-term antibiotics for preventing recurrent urinary tract infection in children
Long-term anticoagulation treatment with low molecular weight heparin versus a vitamin K antagonist in patients with VTE and active cancer
Long-term effect of staff education and on-the-job training on patient urinary incontinence outcomes
Long-term effects of anti-vascular endothelial growth factor therapies for exudative age-related macular degeneration
Long-term effects of anti-vascular endothelial growth factor therapies for neovascular age-related macular degeneration
Long-term effects of weight-reducing diets in hypertensive patients
Long-term efficacy and safety of ciclosporin (cyclosporin) for atopic eczema
Long-term efficacy and safety of oral azathioprine for atopic eczema
Long-term efficacy of autologous pancreatic islet cell transplantation (after pancreatectomy) for improved glycaemic control in patients with diabetes
Long-term efficacy of UVA1 phototherapy for acute atopic eczema
Long-term outcomes of hormonal treatment for infantile spasms
Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with mild or severe endometriosis
Long-term safety and adverse effects of ultraviolet light therapy for atopic eczema in children
Long-term safety and adverse events in topical treatments for chronic plaque psoriasis
Long-term safety of biological therapies for psoriasis, including risk of malignancies
Long-term safety of pimecrolimus and tacrolimus for atopic eczema
Long-term safety of topical corticosteroids for atopic eczema, specifically in relation to bones and eyes
Long-term safety of topical steroids for atopic eczema
Long-term safety of topical steroids for repigmentation in vitiligo
Long-term value of anticholinergic drug treatment for urinary incontinence
Loop diuretics for patients receiving blood transfusions
Losigamone add-on therapy for partial epilepsy
Low bacterial diet versus control diet to prevent infection in cancer patients treated with chemotherapy causing episodes of neutropenia
Low central venous pressure to decrease blood loss and blood transfusion requirements for liver resection
Low cost versus other screening tests to detect cervical cancer or precancer in developing countries
Low dose naltrexone for induction of remission in Crohn's disease
Low dose versus standard dose isotretinoin for acne
Low glycaemic index, or low glycaemic load, diets for diabetes mellitus: long-term effects, quality of life, mortality, morbidity and cost-effectiveness.
Low molecular weight heparin (LMWH) compared with compression therapy for deep vein thrombosis (DVT) prophylaxis.
Low molecular weight heparin for prevention of microvascular occlusion in digital replantation
Low molecular weight heparin versus catheter-directed thrombolysis in proximal lower limb deep vein thrombosis
Low molecular weight heparin versus unfractionated heparin for perioperative thromboprophylaxis in patients with cancer
Low oxygen concentrations for embryo culture in assisted reproductive technologies
Low pressure versus standard pressure pneumoperitoneum in elective laparoscopic cholecystectomy
Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy in patients with acute cholecystitis
Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy in patients with cardiopulmonary disorders
Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birth weight infants
Low-dose Computerised tomography in early diagnosis of patients at high risk of developing lung cancer
Low-dose rate brachytherapy for men with localized prostate cancer
Lower drug dosages for urinary incontinence in older people than used in younger populations
Low-fat diets for acquired hypercholesterolaemia
Loxapine inhaler for psychosis-induced aggression or agitation
Lubiprostone for irritable bowel syndrome in male patients
Lumbar drainage of cerebrospinal fluid for aneurysmal subarachnoid haemorrhage
Lung lavage for meconium aspiration syndrome in newborn infants
Lung protective ventilation strategy for the acute respiratory distress syndrome
Lung recruitment manoeuvres for reducing respiratory morbidity in mechanically ventilated neonates
Lung volume reduction surgery for diffuse emphysema
Lurasidone versus placebo for schizophrenia
Luteal phase support for assisted reproduction cycles
Lutein or zeaxanthin for age-related macular degeneration to slow or prevent distance visual acuity loss or progression
Luteinizing hormone-releasing hormone analogue as a single agent or a combined androgen blockade agent for prostate cancer
Lycopene for the prevention of prostate cancer
Macrolide antibiotics for cystic fibrosis
Macrolides for diffuse panbronchiolitis
Magnesium for primary and secondary dysmenorrhoea
Magnesium for skeletal muscle cramps
Magnesium sulphate for severe acute asthma
Magnesium sulphate for women at term for neuroprotection of the fetus
Magnetic resonance imaging (MRI) versus computed tomography (CT) for the diagnosis of lymph node metastasis in preoperative rectal cancer
Maintenance therapies for multiple myeloma
Maintenance treatment with antipsychotic drugs for schizophrenia
Maintenance treatment with antipsychotic drugs for schizophrenia
Male involvement for increasing the effectiveness of prevention of mother-to-child HIV transmission (PMTCT) programmes
Mammography in combination with breast ultrasonography versus mammography for breast cancer screening in women at average risk
Managed alcohol as a harm reduction intervention for alcohol addiction in populations at high risk for substance abuse
Management of daytime enuresis in children
Management of incontinence after stroke
Management of low-grade squamous intra-epithelial lesions of the uterine cervix: repeat cytology versus immediate referral to colposcopy
Management of lymphoedema following surgery for breast cancer
Management of miscarriage
Management of reported decreased fetal movements for improving pregnancy outcomes
Management of sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy
Management of the clinically negative neck (N0) of supraglottic laryngeal carcinoma
Management of the hepatic lymph nodes during resection of liver metastases from colorectal cancer
Management of trismus induced by cancer therapies in head and neck cancer patients
Manipulative interventions (pronation versus supination) for pulled elbow in young children
Manipulative interventions for reducing pulled elbow in young children
Manipulative therapies for infantile colic
Mannitol compared with hypertonic saline for patients with cystic fibrosis
Mannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy
Manual chest physiotherapy for infective exacerbations of chronic obstructive pulmonary disease
Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract
Manual therapy for adolescent idiopathic scoliosis
Manual therapy for non-specific thoracic pain in adults
Marital therapy for depression
Massage for low back pain
Massage for mechanical neck disorders
Massage for promoting mental and physical health in typically developing infants under the age of six months
Massage therapy for atopic eczema
Massage, reflexology and other manual methods for pain management in labour
Mast cell stabilisers for seasonal and perennial allergic conjunctivitis
Material incentives and enablers in the management of tuberculosis
Maternal consumption of xylitol for preventing dental decay in children
Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing atopic eczema in the child
Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child
Maternal glucose administration for facilitating tests of fetal wellbeing
Maternal hydration for increasing amniotic fluid volume in oligohydramnios and normal amniotic fluid volume
Maternal oxygen administration for fetal distress
Maternal position during caesarean section for preventing maternal and neonatal complications
Maternal prenatal and/or postnatal n-3 fish oil supplementation for preventing allergies in early childhood
Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients
Mechanical bowel preparation for elective colorectal surgery
Mechanical dilatation of the cervix at non-labour caesarean section for reducing postoperative morbidity
Mechanical insufflation-exsufflation for people with neuromuscular disorders
Morrow B, Zampoli M, van Aswegen H, Argent A. Mechanical insufflation-exsufflation for people with neuromuscular disorders (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 8. Art. No.: CD010044. DOI: 10.1002/14651858.CD010044
Mechanical methods for induction of labour
Mechanical traction for chronic neck pain
Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease
Mechanical ventilation versus no mechanical ventilation for people with severe acute asthma
Mechanical versus manual chest compressions for cardiac arrest
Medical and surgical treatment for ocular myasthenia
Medical interventions for fungal keratitis
Medical interventions for high grade vulval intraepithelial neoplasia
Medical interventions for primary open angle glaucoma and ocular hypertension
Medical interventions for the prevention of platinum-induced hearing loss in children with cancer
Medical interventions for treating anthracycline-induced symptomatic and asymptomatic cardiotoxicity during and after treatment for childhood cancer
Medical interventions for treating chronic pelvic pain in women
Medical interventions for treating chronic primary angle-closure glaucoma
Medical treatment for botulism
Medical treatment for small abdominal aortic aneurysms
Medical treatments for incomplete miscarriage
Medical treatments for painful bladder syndrome (interstitial cystitis)
Medical versus surgical interventions for open angle glaucoma
Medical versus surgical interventions for open angle glaucoma
Medical versus surgical termination of pregnancies less than 14 weeks' gestation
Medically assisted hydration for adult palliative care patients
Medication review in hospitalised patients to reduce morbidity and mortality
Medications for increasing milk supply in mothers expressing breastmilk for their preterm hospitalised infants
Meditation (including relaxation techniques) for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Meditation and yoga for depression
Meditation and yoga for schizophrenia
Megavitamins for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Megestrol acetate for treatment of anorexia-cachexia syndrome
Melanocyte transplantation for repigmentation in vitiligo
Melatonin as add-on treatment for epilepsy
Melatonin for non-respiratory sleep disorders in visually impaired children
Melatonin for preoperative anxiety in adults
Melatonin for the treatment of dementia
Melatonin in cancer treatment
Wolf E, Milazzo S, Pilkington K, Liu JP, Zwahlen M, Horneber M. Melatonin in cancer treatment (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No.: CD010145. DOI: 10.1002/14651858.CD010145
Memory Rehabilitation for people with multiple sclerosis
Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke
Mentoring adolescents to prevent drug and alcohol use
Mesalamine (5-ASA) for the management of diverticulitis
Mesalamine for lymphocytic colitis or collagenous colitis
Mesalazine for Crohn's disease in remisson vs no treatment
Mesenchymal stromal cells (MSC) for treating immune-mediated inflammation post-transplantation and in autoimmunity
Metal protein attenuating compounds for the treatment of Alzheimer's dementia
Metformin added to insulin therapy for type 1 diabetes mellitus in adolescents
Methadone at tapered doses for the management of opioid withdrawal
Methadone for cancer pain
Methadone for chronic non-cancer pain in adults
Methenamine hippurate for preventing urinary tract infections
Methods for administering subcutaneous heparin during pregnancy
Methods of decreasing infection to improve outcomes after liver resections
Methods of milk expression for lactating women
Methods of term labour induction for women with a previous caesarean section
Methods to decrease blood loss and transfusion requirements for liver transplantation
Methotrexate combination therapy with non-biologic disease modifying antirheumatic drugs for treating rheumatoid arthritis in adults
Methotrexate for ankylosing spondylitis
Methotrexate for induction of remission in refractory Crohn's disease
Methotrexate for Lyme disease
Methotrexate for maintenance of remission in Crohn's disease
Methotrexate for maintenance of remission in ulcerative colitis
Methotrexate for psoriasis
Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis: A network meta-analysis
Methotrexate vs other systemic non-biological or biological treatments for people with psoriasis
Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents
Methylprednisolone for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Metoclopramide for migration of naso-enteral tube
Metronidazole or tinidazole for Lyme disease
Micronutrient supplementation in pregnant women with HIV infection
Micropigmentation for vitiligo
Micropressure therapy for refractory Meniere's disease
Microwave coagulation for liver metastases
Microwave thermotherapy for benign prostatic hyperplasia
Mid-childhood (ages 6-10 years) programmes to prevent substance use and risky sexual behaviour in young people
Mifepristone for uterine fibroids
Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Milnacipran for neuropathic pain and fibromyalgia in adults
Milnacipran versus other antidepressive agents for depression
Mind-body interventions during pregnancy for preventing or treating women's anxiety
Mindfulness-based 'third wave' cognitive and behavioural therapies versus other psychological therapies for depression
Minimal effective dose of octreotide to prevent post-ERCP pancreatitis
Minimally invasive discectomy versus microdiscectomy/discectomy for symptomatic lumbar disc herniation
Minimally invasive parathyroid surgery for hyperparathryoidism
Minimally invasive sling operations for stress urinary incontinence in women
Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children
Minimally invasive versus open surgery for reversal of tubal sterilization
Miniport versus standard ports for elective laparoscopic cholecystectomy
Miniport versus standard ports for emergency laparoscopic cholecystectomy
Minipunch skin grafts for repigmentation in vitiligo
Minocycline for acne vulgaris: efficacy and safety
Mirror therapy for improving motor function after stroke
Mirror therapy, graded motor imagery and virtual illusion for the management of chronic pain
Mirtazapine for depression
Mirtazapine versus other antidepressive agents for depression
Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery
MLN-02 for induction of remission in ulcerative colitis
Mobile clinics for women's and children's health
Mobile phone messaging for communicating results of medical investigations
Mobile phone messaging for facilitating self-management of long-term illnesses
Mobile phone messaging for preventive health care
Mobile phone messaging reminders for attendance at healthcare appointments
Mobile phone text messaging for promoting adherence to antiretroviral therapy in patients with HIV infection
Mobile phone-based interventions for smoking cessation
Models for individual oral health promotion and their effectiveness
Modern combined oral contraceptives for pain associated with endometriosis
Modifications of the Epley (canalith repositioning) manoeuvre for posterior canal benign paroxysmal positional vertigo (BPPV)
Modifications of the Epley (canalith repositioning) manoeuvre for posterior canal benign paroxysmal positional vertigo (BPPV)
Mohs micrographic surgery versus surgical excision for periocular basal cell carcinoma
Mometasone for asthma in adults and children
Momordica charantia for type 2 diabetes mellitus
Monoamine oxidase B inhibitors for early Parkinson's disease
Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome
Monochromatic excimer light (MEL) for repigmentation in vitiligo
Monoclonal antibody for reducing the risk of respiratory syncytial virus infection in children
Monoclonal antibody treatment for recurrent head and neck cancer
Monoclonal CCR5 antibody for treatment of people with HIV infection
Monosodium glutamate avoidance for chronic asthma in adults and children
Monosodium glutamate avoidance for chronic asthma in adults and children
Monotherapy for seizure control in neonatal seizures
Monotherapy versus combination therapy used as first-line therapy for primary hypertension
Monotherapy with benzoyl peroxide or topical retinoids versus combination topical therapy in the initial treatment of mild acne
Morning versus evening induction of labour for improving outcomes
Morphine for acute decompensated heart failure
Morphine in acute coronary syndromes
Mortality and adverse effects of peginterferon alpha-2a versus peginterferon alfa-2b in treatment of chronic hepatitis C
Mortality and quality of life with protective defunctioning stoma versus no stoma protection in low anterior resection for rectal carcinoma
Most effective probiotic treatment (species, strain, dose) for irritable bowel syndrome
Motivational interventions for drug and alcohol use in schizophrenia
Motivational interviewing for improving outcomes in youth living with HIV
Motivational interviewing for improving outcomes in youth living with HIV
Motivational interviewing for substance abuse
Moulding helmets for head shape abnormality (plagiocephaly) in babies
MRI scan in addition to ultrasound for diagnosis of placenta accreta in high risk pregnancy, and likelihood of caesarean hysterectomy
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease
Multi-channel cystometry for urinary incontinence or overactive bladder.
Multi-component interventions for nocturia
Multidimensional rehabilitation programmes for adult cancer survivors
Multidisciplinary care for adults with amyotrophic lateral sclerosis or motor neuron disease
Multidisciplinary rehabilitation after primary brain tumour treatment
Multidisciplinary rehabilitation following botulinum toxin and other focal intramuscular treatment for post-stroke spasticity
Multidisciplinary rehabilitation for adults with multiple sclerosis
Multidisciplinary rehabilitation for follow-up of women treated for breast cancer
Multifocal versus monofocal intraocular lenses after cataract extraction
Multimedia educational interventions for consumers about prescribed and over-the-counter medications
Multinutrient fortification of human breast milk for preterm infants following hospital discharge
Multiple versus one or more antiplatelet agents for preventing early recurrence after ischaemic stroke or transient ischaemic attack
Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers
Muscle energy technique for non-specific low-back pain
Muscle relaxants for pain management in rheumatoid arthritis
Music education for improving reading skills in children and adolescents with dyslexia
Music for stress and anxiety reduction in coronary heart disease
Music interventions for improving psychological and physical outcomes in cancer patients
Music interventions for mechanically ventilated patients
Music therapy for attention deficit hyperactivity disorder (ADHD) in children and adolescents
Music therapy for depression
Music therapy for people with dementia
Music therapy for people with schizophrenia and schizophrenia-like disorders
Mutation-specific therapies that potentiate cystic fibrosis transmembrane conductance regulator (CFTR) function in cystic fibrosis
My 18 month-old child has very unstable asthma. What is the best treatment?
My daughter is taking olanzapine for schizophrenia. Could I give her Nytol (diphenhydramine) and olanzapine?
My daughter who has been diagnosed with asthma only seems to become wheezy when she takes her steroid inhaler. Should this be happening?
My son finds it difficult to use a spacers and masks to take his inhaled medication for his asthma. How do I know he is getting the correct dose? Are there alternatives?
My son has schizophrenia. He was on Clozapine and transferred to aripiprazole. He's now becoming unwell. Is it better to switch straight back to clozapine, taper the doses or combine the two?
My two-year old child has been taking salbutamol for asthma and it does not seem to help. Is there a better treatment?
Mycophenolate mofetil (MMF) for the treatment of connective tissue disease-associated interstitial lung disease (ILD)
Mycophenolate mofetil for relapsing-remitting multiple sclerosis
Mycophenolate mofetil versus methotrexate for prevention of acute graft-versus-host disease in patients receiving allogeneic hematopoietic stem cell transplantation
Myomectomy of fibroids for improving chances of becoming pregnant
N-acetylcysteine for sepsis and systemic inflammatory response in adults
Naftidrofuryl for dementia
Naftidrofuryl for intermittent claudication
Naloxone for opiate-exposed newborn infants
Narrow band imaging versus conventional white light colonoscopy for the detection of colorectal polyps
Narrow band UVB monotherapy for repigmentation in vitiligo
Narrow excision margins versus wide excision margins on disease-specific survival of patients with primary cutaneous melanoma
Narrowband UVB compared to PUVA for psoriasis
Nasal versus oral route for placing feeding tubes in preterm or low birth weight infants
Natalizumab (alone or in combination with other therapies) for multiple sclerosis
Natalizumab for relapsing remitting multiple sclerosis
Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months
Nebulised surfactant in preterm infants with or at risk of respiratory distress syndrome
Nebuliser systems for drug delivery in cystic fibrosis
Nebulisers versus hand-held inhalers to deliver beta2-agonist bronchodilator drugs in non-acute asthma
Nebulized epinephrine for croup in children
Nebulized hypertonic saline solution for acute bronchiolitis in infants
Neck dissection following chemo-radiotherapy in advanced head and neck squamous cell carcinoma
Nedocromil sodium for chronic asthma in children
Needling for encapsulated trabeculectomy filtering blebs
Needling for encapsulated trabeculectomy filtering blebs
Negative pressure wound therapy for partial-thickness burns
Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus
Neoadjuvant chemotherapy plus surgery versus surgery for cervical cancer
Neoadjuvant chemotherapy versus none for resectable gastric cancer
Neostigmine for reversal of neuromuscular block in paediatric patients
Nerve blockade for reducing the incidence of delirium
Neuraminidase inhibitors for preventing and treating influenza in children
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children
Neuraminidase inhibitors for the treatment of influenza infection in people with cystic fibrosis
Neuraxial blockade for the prevention of postoperative mortality and major morbidity: an overview of Cochrane systematic reviews
Neurofeedback for attention deficit-hyperactivity disorder (ADHD)
Neuromodulation with implanted electrodes for urinary storage and voiding dysfunction in adults
Neuromodulators for pain management in rheumatoid arthritis
Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease
Neuromuscular electrical stimulation for stress urinary incontinence
Neuroprotection for prevention and treatment of glaucoma in adults
Neuroprotection for treatment of glaucoma in adults
Neuroprotective agents i.e. memantine for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Neuropsychological rehabilitation for multiple sclerosis
Neuropsychological rehabilitation for stroke
Neuropsychological tests for the diagnosis of Alzheimer's disease dementia and other dementias: a generic protocol for cross-sectional and delayed-verification studies
Neurosurgery for depressive disorders
Neurosurgical interventions for the treatment of classical trigeminal neuralgia
New treatments compared to established treatments in randomized trials
Newborn screening for homocystinuria
Newer anticoagulants such as fondaparinux and ximelagatran in cancer patients with central venous catheters
Newer generation antidepressants for depressive disorders in children and adolescents
Niacin for primary and secondary prevention of cardiovascular events
Nicotine receptor partial agonists for smoking cessation
Nicotine replacement therapy for smoking cessation
Nicotine vaccines for smoking cessation
Nidotherapy for people with schizophrenia
Nidotherapy for people with schizophrenia
Nitrates for achalasia
Nitric oxide donors for cervical ripening in first-trimester surgical abortion
Nitric oxide donors for the treatment of preterm labour
Nitrous oxide for colonoscopy
Noise reduction management in the neonatal intensive care unit for preterm or very low birthweight infants
Non pharmacological interventions for spasticity in multiple sclerosis
Non pharmacological interventions for spasticity in multiple sclerosis
Non steroidal anti-inflammatory drugs for the prevention of colorectal adenomas
Non surgical therapy for anal fissure
Non-acoustic benefits of bone-anchored hearing aids
Non-antibiotic pharmaceutical treatment of acute otitis media
Non-antibiotic treatments for sore throat
Non-cardioselective beta-blockers versus placebo in stable angina for improvement of mortality
Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome
Non-drug interventions for pain in Lyme neuroborreliosis
Non-drug therapies for lower limb muscle cramps
Non-fluoride topical remineralising agents containing calcium and/or phosphate for controlling dental caries
Non-immunosuppressive treatment for IgA nephropathy
Non-invasive brain stimulation techniques for chronic pain
Non-invasive positive pressure ventilation
Non-invasive positive pressure ventilation for prevention of complications after pulmonary resection in lung cancer patients
Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma
Non-invasive ventilation for cystic fibrosis
Non-invasive ventilation for ventilatory failure in asthma
Non-laser light treatments versus conventional, drug therapies for acne
Nonlatex versus latex male condoms for contraception
Non-opioid drugs for pain management in labour
Non-penetrating filtration surgery versus trabeculectomy for open angle glaucoma
Non-pharmaceutical management of respiratory morbidity in children with severe global developmental delay
Non-pharmacological and non-surgical interventions for managing retained placenta
Non-pharmacological and pharmacological interventions for primary prevention of gallbladder stones in adults
Non-pharmacological interventions for alleviating pain during orthodontic treatment
Non-pharmacological interventions for caregivers of stroke survivors
Non-pharmacological interventions for depression in adults and children with traumatic brain injury
Non-pharmacological interventions for epilepsy in people with intellectual disabilities
Non-pharmacological interventions for improving work participation in patients with inflammatory arthritis
Non-pharmacological interventions for perceptual disorders following stroke and other adult-acquired, non-progressive brain injury
Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack
Non-pharmacological interventions for preventing venous insufficiency in a standing worker population
Non-pharmacological interventions for women with postpartum fatigue
Non-pharmacological interventions that allow safe wandering for people with dementia
Non-pharmacological management interventions for COPD: an overview of Cochrane systematic reviews
Non-pharmacological management of infant and young child procedural pain
Non-pharmacological treatments for constipation in children
Non-resection versus resection for an asymptomatic primary tumour in patients with unresectable Stage IV colorectal cancer
Non-selective beta agonists versus beta2-agonists for acute asthma
Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery
Nonsteroidal anti-inflammatory drugs (NSAID) and aspirin for preventing colorectal adenomas and carcinomas in general population
Nonsteroidal anti-inflammatory drugs (NSAID) and aspirin for preventing colorectal adenomas and carcinomas in patients with previous adenomas and/or genetic disposition
Nonsteroidal anti-inflammatory drugs (NSAID) and aspirin for preventing recurrence and metachronous colorectal carcinomas in patients previously treated for colorectal cancer
Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies
Non-steroidal anti-inflammatory drugs for acute gout
Non-steroidal anti-inflammatory drugs for heavy menstrual bleeding
Non-steroidal anti-inflammatory drugs for pain in women with endometriosis
Non-surgical interventions for convergence insufficiency
Non-surgical interventions for human papilloma virus-positive local advanced oropharyngeal squamous cell cancer
Non-surgical interventions for treating heavy menstrual bleeding (menorrhagia) in women with bleeding disorders
Notification and support for people exposed to the risk of Creutzfeldt-Jakob disease (CJD) (or other prion diseases) through medical treatment (iatrogenically)
Nurse education of parents of children with atopic eczema
Nurse versus physician-led care for the management of asthma
Nurse-led titration of angiotensin converting enzyme inhibitors, beta-adrenergic blocking agents and angiotensin receptor blockers for patients with left ventricular systolic dysfunction
Nurse-led versus doctor-led clinics in the management of childhood atopic eczema
Nurse-led versus doctor-led preoperative assessment for elective surgical patients requiring regional or general anaesthesia
Nursing interventions to assist elders in coping with hearing impairment
Nutrient-enriched formula versus standard term formula for preterm infants following hospital discharge
Nutritional interventions for liver-transplanted patients
Nutritional interventions for reducing gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy
Nutritional interventions for reducing morbidity and mortality in people with HIV
Nutritional interventions for survivors of childhood cancer
Nutritional supplementation for hip fracture aftercare in older people
Nutritional supplementation for stable chronic obstructive pulmonary disease
Nutritional support for acute kidney injury
Nutritional support for critically ill children
Nutritional support for head and neck cancer patients receiving radiotherapy
Nutritional support for liver disease
Nutritional support in children and young people with cancer undergoing chemotherapy
Occupational safety and health regulation and legislation enforcement tools for preventing occupational diseases and injuries
Occupational therapy for care home residents with stroke
Occupational therapy for cognitive impairment in stroke patients
Octreotide for the treatment of chylothorax in neonates
Oculogyric crisis in antipsychotic treatment of schizophrenia
Oestrogen therapy compared to placebo as well as, and as a supplement to, both surgical or non-surgical management in post-menopausal women with urinary incontinence.
Oestrogen therapy for urinary incontinence in post-menopausal women
Oestrogens for treatment or prevention of pelvic organ prolapse in postmenopausal women
Oestrogens for urinary incontinence in women
Of alarms, desmopressin or tricyclic drugs, which is most effective as the first line treatment of nocturnal enuresis in children?
Off-pump versus on-pump coronary artery bypass grafting for ischaemic heart disease
Olanzapine discontinuation for schizophrenia
Olanzapine for cannabis cravings or use in people with psychosis and coexisting substance misuse.
Older People's Exercise intervention in Residential and nursing Accommodation (OPERA)
Omega 3 and omega 6 fatty acids for prevention of atopic eczema
Omega 3 fatty acid for the prevention of cognitive decline and dementia
Omega 3 fatty acid supplementation for preventing and slowing the progression of age-related macular degeneration
Omega 3 fatty acids for maintenance of remission in Crohn's disease
Omega 3 fatty acids for preventing or slowing the progression of age-related macular degeneration
Omega 3 fatty acids to halt progression of age-related macular degeneration
Omega 3 fatty acids to prevent age-related macular degeneration
Omega-3 fatty acids for cystic fibrosis
Omega-3 fatty acids supplementation for autism spectrum disorders (ASD)
Omentoplasty for esophagogastrostomy after esophagectomy
Once an antipsychotic medication is started for someone for a first episode of psychosis, how long do they need to keep taking them before we can start reducing the dose or consider stopping medication?
Once daily betamethasone for atopic eczema compared to once daily "new" topical corticosteroids (mometasone furoate, fluticasone propionate, methylprednisolone aceponate)
Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis
One site versus two site phacotrabeculectomy for primary open angle glaucoma
One-step techniques for primary distal hypospadias in children and adolescents
One-to-one dietary interventions undertaken in a dental setting to change dietary behaviour
One-to-one psychological therapy versus group interventions for schizophrenia
Open fasciotomy for Dupuytren’s contractures of the hand
Open preperitoneal techniques versus Lichtenstein repair for elective inguinal hernias
Open retropubic colposuspension for urinary incontinence in women
Open versus laparoscopic ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis
Open, laparoscopic and robot-assisted laparoscopic radical prostatectomy for localised prostate cancer
Operative caries management in adults and children
Operative versus conservative management for 'fetal distress' in labour
Opioid therapy for treating rheumatoid arthritis pain
Opioids for agitation in dementia
Opioids for low back pain
Opioids for osteoarthritis of the knee or hip
Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy
Optical correction of refractive error for preventing and treating eye symptoms in computer users
Optimal allergen dosage of sublingual immunotherapy for allergic rhinitis
Optimal analgesic(s) for pain after tonsillectomy in children
Optimal antibiotic treatment for early disseminated Lyme disease
Optimal antibiotic treatment for early Lyme neuroborreliosis
Optimal antibiotic treatment for late Lyme neuroborreliosis
Optimal antibiotic treatment for Lyme disease in patients presenting with erythema migrans
Optimal antiviral therapy of chronic hepatitis B
Optimal approach to pelvic floor muscle training for urinary incontinence in women
Optimal cut-off value for protein Z in the estimation of thrombotic risk
Optimal dilution of topical corticosteroids for atopic eczema
Optimal dosage of ACTH (or tetracosactide) for infantile spasms
Optimal dose of folate supplementation in treatment of psoriasis with methotrexate
Optimal dose of stereotactic radiosurgery for acoustic neuromas
Optimal dosing protocols for UVB therapy of chronic atopic eczema
Optimal dosing regime/re-treatment benefits of anti-vascular endothelial growth factor modalities in the treatment of age-related macular degeneration
Optimal duration of exclusive breastfeeding
Optimal duration of pegatheron plus ribavirin therapy for chronic hepatitis C in patients with HIV
Optimal Duration of pulmonary rehabilitation in COPD patients for quality of life and exercise capacity
Optimal duration of therapy in HBeAg-negative hepatitis B patients
Optimal follow up following recovery from an asthma attack
Optimal frequency and duration of acupuncture sessions for migraine prophylaxis
Optimal frequency of application of topical corticosteroids for atopic eczema
Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease
Optimal loading dose of warfarin for the initiation of oral anticoagulation
Optimal maintenance regimen after cessation of UVA1 phototherapy for acute atopic eczema
Optimal management of anticoagulated moderate-high risk patients with atrial fibrillation who present with an acute coronary syndrome and/or undergo percutaneous coronary intervention +/- stent implantation
Optimal method of diagnosis of peripheral arterial disease in patients with diabetes related foot disease
Optimal method of revascularisation of the ulcerated foot in patients with diabetes and peripheral arterial disease
Optimal patient reported outcome measurement of health related quality of life in diabetic foot patients
Optimal positron emission tomography intensity for defining the gross tumour volume of a lung tumour
Optimal primary surgical treatment for advanced epithelial ovarian cancer
Optimal ribivirin dose for chronic hepatitis C when taking in combination with pegylated interferon alpha-2a or alpha-2b
Optimal size and duration of placement of self-expanding plastic stents for benign oesophageal strictures
Optimal surgical management of vesicovaginal and/or urethrovaginal fistula
Optimal surgical procedure for obstruction from primary left colorectal carcinoma
Optimal surgical treatment for anorectal fistula
Optimal time for initiating antiretroviral therapy (ART) in HIV-positive, treatment-naive children aged 24 to 59 months (2 to 5 years old)
Optimal timing for antiretroviral therapy initiation in patients with HIV infection and concurrent cryptococcal meningitis
Optimal vehicle for application of topical corticosteroids for atopic eczema
Optimisation of thyroid hormone dose for treatment of myxedema coma
Optimum analgesic for pain in Lyme neuroborreliosis
Optimum antibiotic treatment for Lyme arthritis
Optimum chemotherapy backbone for bevacizumab treatment of metastatic colorectal cancer
Optimum dexamethasone dosing for recovery following tonsillectomy
Optimum imfliximab introduction period for steroid withdrawal in inflammatory bowel disease
Optimum method of altered fractionated radiotherapy for head and neck cancer
Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis
Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis
Oral analgesia for relieving post-caesarean pain
Oral and systemic steroids at different doses for acute asthma in hospitalised children
Oral antifungal medication for toenail onychomycosis
Oral antihistamine-decongestant-analgesic combinations for the common cold
Oral antioxidants plus phenylalanine for repigmentation in vitiligo
Oral betamimetics for maintenance therapy after threatened preterm labour
Oral calorie supplements for cystic fibrosis
Oral cobamamide for repigmentation in vitiligo
Oral contraceptive pill as a treatment in women with primary dysmenorrhoea
Oral contraceptive pill compared to nonsteroidal anti-inflammatories for treating women with primary dysmenorrhoea
Oral contraceptives containing drospirenone for premenstrual syndrome
Oral dapsone for acne
Oral decongestants alone for seasonal allergic rhinitis in adolescents and adults
Oral evening primrose oil and borage oil for eczema
Oral fumaric acid esters for psoriasis
Oral gingko biloba extract for repigmentation in vitiligo
Oral H1 antihistamines as monotherapy for eczema
Oral health advice for people with serious mental illness
Oral immunotherapy for milk allergy
Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants
Oral levamisole as an adjuvant to vaccination for hepatitis B virus seroprotection
Oral levamisole plus mometasone furoate cream for repigmentation in vitiligo
Oral minipulses of betamethasone for repigmentation in vitiligo
Oral minipulses of betamethasone plus narrow band UVB for repigmentation in vitiligo
Oral minipulses of betamethasone plus PUVA for repigmentation in vitiligo
Oral naltrexone maintenance treatment for opioid dependence
Oral phenylalanine followed by UVA for repigmentation in vitiligo
Oral pimecrolimus for psoriasis
Oral Polypodium leucotomos plus narrow band UVB for repigmentation in vitiligo
Oral Polypodium leucotomos plus PUVA for repigmentation in vitiligo
Oral psoralens with sunlight (oral PUVAsol) for repigmentation in vitiligo
Oral steroids for nasal polyps
Oral substitution treatment of injecting opioid users for prevention of HIV infection
Oral theophylline for stable asthma in adults
Oral traditional Chinese medication for adhesive small bowel obstruction
Oral treatments for fungal infections of the skin of the foot
Oral vaccines for preventing cholera
Oral vasodilators for primary Raynaud's phenomenon
Oral versus intravenous steroids for treatment of relapses in multiple sclerosis
Oral xanthines as maintenance treatment for asthma in children
Oral zinc for arterial and venous leg ulcers
Oral zinc for treating diarrhoea in children
Orbital radiotherapy for adult thyroid eye disease
Organisational interventions for improving wellbeing and reducing work-related stress in teachers
Oropharyngeal dysphagia behavioral treatments -- impact of dysphagia treatment on individuals' postcancer treatments
Orthodontic treatment for bimaxillary proclination in children and adults
Orthodontic treatment for deep bite and retroclined upper front teeth in children
Osmotic and stimulant laxatives for the management of childhood constipation
Osmotic therapies added to antibiotics for acute bacterial meningitis
Osteotomy for knee osteoarthritis
Osteotomy, compression and other modifications of surgical techniques for internal fixation of extracapsular hip fractures
Outcomes of assisted reproduction after excisional surgery with drainage and ablation of ovarian endometriomata
Outpatient versus inpatient treatment for acute pulmonary embolism
Ovarian function after drainage and ablation of ovarian endometriomata
Over the counter (OTC) artificial tear drops for dry eye syndrome
Over-the-counter (OTC) medications for acute cough in children and adults in ambulatory settings
Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults
Over-the-counter (OTC) treatments for acne, apart from benzoyl peroxide
Oxcarbazepine for acute affective episodes in bipolar disorder
Oxcarbazepine for neuropathic pain
Oxygen therapy for acute myocardial infarction
Oxygen therapy for cystic fibrosis
Oxygen therapy for heart failure
Oxygen therapy for pneumonia in adults
Oxygen versus air for nebulising beta-agonist bronchodilators in acute asthma
Oxytocin augmentation of labour in women with epidural analgesia for reducing operative deliveries
Oxytocin infusion regimens for induction of labour
Oxytocin versus no treatment or delayed treatment for slow progress in the first stage of spontaneous labour
Pacifier use versus no pacifier use in breastfeeding term infants for increasing duration of breastfeeding
Pacing for drug-refractory or drug-intolerant hypertrophic cardiomyopathy
Paclitaxel for maintenance chemotherapy for ovarian cancer
Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondylarthritis) and gastrointestinal or liver comorbidity
Pain management for patients with an acute painful sickle cell episode
Pain management for rheumatoid arthritis and cardiovascular or renal comorbidity
Pain management for tubal sterilization by hysteroscopy
Pain management for women in labour
Pain management prior to, during and following treatment for head and neck cancer
Pain relief for women undergoing oocyte retrieval for assisted reproduction
Pain relief for women with cervical intraepithelial neoplasia undergoing colposcopy treatment
Pain-relieving agents for infant colic
Paliperidone for schizophrenia
Paliperidone palmitate for schizophrenia
Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis
Palliative care for heart failure
Palliative endobronchial brachytherapy for non-small cell lung cancer
Palliative endobronchial brachytherapy for non-small cell lung cancer
Palliative pharmacological sedation for symptom relief in terminally ill adults
Palliative surgery versus medical management for bowel obstruction in ovarian cancer
Pancreatic enzymes for chronic pancreatitis
Pancreaticoduodenectomy (classic Whipple) versus pylorus-preserving pancreaticoduodenectomy (pp Whipple) for surgical treatment of periampullary and pancreatic carcinoma
Pantothenic acid (vitamin B5) for acne
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm and/or low-birth-weight infants
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults
Paracetamol for low back pain
Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy
Parathyroid hormone alone or in combination with antiresorptive therapy for bone mineral density
Parathyroid hormone for the treatment of osteoporosis
Parathyroidectomy for chronic kidney disease-mineral and bone disorder (CKD-MBD)
Parent training interventions for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years
Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation
Parenteral opioids for maternal pain relief in labour
Parenteral versus oral iron therapy for adults and children with chronic kidney disease
Parenting interventions for the prevention of unintentional injuries in childhood
Parent-mediated early intervention for young children with autism spectrum disorders (ASD)
Paroxetine depression
Partial exchange transfusion to prevent neurodevelopmental disability in infants with polycythemia
Partial liquid ventilation for the prevention of mortality and morbidity in paediatric acute lung injury and acute respiratory distress syndrome
Partially hydrolyzed whey protein formula for preventing atopic eczema in infants
Participation in environmental enhancement and conservation activities for health and well-being in adults
Passive immunisation with monoclonal anti-Abeta antibodies for the treatment of Alzheimer's disease
Patellar taping for patellofemoral pain syndrome in adults
Patellar tendon versus hamstring tendon autograft for anterior cruciate ligament rupture in adults
Pathogen-reduced platelets for the prevention of bleeding
Patient adherence to treatment in heart failure
Patient controlled intravenous analgesia versus epidural analgesia for pain following intra-abdominal surgery
Patient education and counselling for promoting adherence to treatment for tuberculosis
Patient education for chronic low back pain
Patient education for neck pain
Patient education for preventing diabetic foot ulceration
Patient education in the management of coronary heart disease
Patient education of prostate cancer to improve outcomes
Patient education on multifactorial genetic conditions for those at risk, and effect on knowledge, psychological measures and treatment uptake
Patient information on treatment options for urinary incontinence to improve access to appropriate care
Patient level factors associated with benefit of kidney transplantation for outcomes other than mortality
Patient positioning (mobilisation) and bracing for pain relief and spinal stability in metastatic spinal cord compression in adults
Patient related outcome measures for follow-up after gynaecological cancer treatment
Patients on antidiabetic medication testing false positive for recreational drugs
Paying for performance to improve the delivery of health interventions in low- and middle-income countries?
Pedicle screw constructs in adolescent idiopathic scoliosis
Peer mentor programmes to increase the number of people at increased risk of hepatitis B and C, who are then tested and treated
Peer support for improving service engagement for people with psychosis and coexisting substance misuse
Peer support interventions for family carers of adults with chronic mental or physical illness who are living at home
Peginterferon plus ribavirin versus no treatment for chronic hepatitis C in patients with HIV
Pegylated granulocyte colony stimulating factor versus non-pegylated granulocyte colony stimulating factor for patients after hematopoietic stem cell transplantation
Pegylated granulocyte colony stimulating factor versus non-pegylated granulocyte colony stimulating factor for peripheral stem cell mobilization
Pegylated interferon alpha-2a plus ribavirin vs pegylated interferon alpha-2b plus ribavirin for chronic hepatitis C
Pegylated interferon and ribavirin in liver transplant candidates and recipients with HCV cirrhosis
Pegylated liposomal doxorubicin for first-line treatment of epithelial ovarian cancer
Pelvic artery catheterisation and embolisation in women with placenta accreta undergoing caesarean section, for uterine conservation and reduced maternal morbidity
Pelvic floor exercise to treat urinary incontinence in men after prostate surgery
Pelvic floor exercises for urge urinary incontinence.
Pelvic floor muscle function and bladder training for primary prevention of urinary incontinence in older adults
Pelvic floor muscle training as part of prenatal care to prevent incontinence
Pelvic floor muscle training compared with another active treatment for urinary incontinence in adults
Pelvic floor muscle training for men post-prostatectomy
Pelvic floor muscle training for prevention and treatment of urinary and faecal incontinence in antenatal and postnatal women
Pelvic floor muscle training for women with stress urinary incontinence
Pelvic floor muscle training in combination with another therapy compared with the other therapy alone for urinary incontinence in women
Pelvic floor muscle training in combination with another therpay compared with the other therapy alone
Pemetrexed disodium in combination with cisplatin versus other cytotoxic agents or supportive care for the treatment of malignant pleural mesothelioma
Penetrating keratoplasty versus deep anterior lamellar keratoplasty for treating keratoconus
Penicinillamine for Wilson's disease
Pentoxifylline compared to medical treatment or surgery in women with subfertility and endometriosis
Pentoxifylline for alcoholic hepatitis
Pentoxifylline for diabetic kidney disease
Pentoxifylline for endometriosis
Pentoxifylline for intermittent claudication
Pentoxifylline for the prevention of bronchopulmonary dysplasia in preterm infants
Pentoxifylline for treating venous leg ulcers
Pentoxyfilline as a treatment for proteinuria
Perazine for schizophrenia
Percutaneous acetic acid injection for early hepatocellular carcinoma
Percutaneous balloon cryoablation for treating atrial fibrillation
Percutaneous electrical nerve stimulation (PENS) for refractory neuropathic pain
Percutaneous endoscopic gastrostomy versus nasogastric tube feeding for adults with swallowing disturbances
Percutaneous ethanol injection for early hepatocellular carcinoma
Percutaneous fasciotomy for Dupuytren’s contractures of the hand
Percutaneous needle aspiration, injection, and reaspiration with or without benzimidazole coverage for uncomplicated hepatic hydatid cysts
Percutaneous pinning for distal radial fractures in adults
Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis
Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis patients
Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis
Percutaneous transluminal rotational atherectomy for coronary artery disease
Perflouro alkoxy plastic versus metal palliative biliary stents for obstructing pancreatic carcinoma
Performance measures and outcome in Chronic Heart Failure
Perfusion techniques for liver retrieval in liver donors
Perianal injectable bulking agents as treatment for faecal incontinence in adults
Perianal injectable bulking agents as treatment for faecal incontinence in adults
Pericyazine for schizophrenia
Peri-implantation glucocorticoid administration for assisted reproductive technology cycles
Perineal dilators for facilitating the second stage of labour
Perineal techniques during the second stage of labour for reducing perineal trauma
Periodontal treatment (scaling, root planning, oral hygiene education) versus no treatment in pregnant women with periodontitis for reducing stillbirth, preterm birth and low birth weight
Perioperative antibiotics to prevent infection after first-trimester abortion
Perioperative blood transfusions and recurrence of colorectal cancer
Perioperative buffered versus non-buffered fluid administration for surgery in adults
Perioperative corticosteroids for preventing complications following facial plastic surgery
Perioperative dexmedetomidine for acute pain after abdominal surgery in adults
Perioperative enhanced recovery programmes for gynaecological cancer patients
Perioperative glycaemic control for diabetic patients undergoing surgery
Peri-operative glycaemic control regimens for preventing surgical site infections in adults
Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery
Perioperative local anaesthesia for reducing pain following tonsillectomy
Perioperative nutrition for the treatment of bladder cancer by radical cystectomy
Perioperative nutrition interventions for women with ovarian cancer
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery
Perioperative transversus abdominis plane (TAP) blocks for analgesia after abdominal surgery
Peripheral iridotomy for pigmentary glaucoma
Peritoneal closure versus no peritoneal closure for decreasing wound complications after non-obstetric abdominal operations
Permissive hypercapnia for the prevention of morbidity and mortality in mechanically ventilated newborn infants
Permissive hypoxaemia versus normoxaemia for mechanically ventilated critically ill patients
Person centred counselling for psychosis
Personalised risk communication for informed decision making about taking screening tests
Pessaries (mechanical devices) for pelvic organ prolapse in women
Pharmacist-led interventions for adults with asthma or COPD
Pharmacologic interventions for treating phantom limb pain
Pharmacologic treatment for memory disorder in multiple sclerosis
Pharmacologic treatment of depression in multiple sclerosis
Pharmacologic treatment to prevent fractures in people with low bone density or osteoporosis
Pharmacological agents for preventing inadvertent perioperative hypothermia
Pharmacological interventions for ADHD symptoms in children with fetal alcohol spectrum disorders (FASD)
Pharmacological interventions for clozapine-induced hypersalivation
Pharmacological interventions for depression in people with traumatic brain injury
Pharmacological interventions for epilepsy in people with intellectual disabilities
Pharmacological interventions for improving respiratory function in amyotrophic lateral sclerosis
Pharmacological interventions for preventing recurrent urinary stones in adults and children
Pharmacological interventions for self-injurious behaviour in adults with intellectual disabilities
Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease
Pharmacological interventions for treating acute hyperkalaemia in adults
Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy
Pharmacological interventions other than botulinum toxin for spasticity after stroke
Pharmacological maintenance therapy in pregnant women with an opiate dependency
Pharmacological therapies for maintenance treatments of opium dependence
Pharmacological therapy for idiopathic lumbosacral plexopathy
Pharmacological treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children with comorbid tic disorders
Pharmacological treatment for depression during opioid agonist treatment for opioid dependence
Pharmacological treatment for Kleine-Levin Syndrome
Pharmacological treatment for Kleine-Levin Syndrome
Pharmacological treatment for pain in Guillain-Barr? syndrome
Pharmacological treatment of depression in patients with a primary brain tumour
Pharmacological treatment of vascular risk factors for reducing mortality and cardiovascular events in patients with abdominal aortic aneurysm
Pharmacological treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for Guillain Barr? syndrome
Pharmacological treatments for fatigue associated with palliative care
Pharmacological treatments for preventing epilepsy following traumatic head injury
Pharmacotherapy combined with behavioural support and delivered by health professionals compared to brief advice, behavioural support or pharmacotherapy alone vs smokeless tobacco
Pharmacotherapy for bipolar disorder in older people
Pharmacotherapy for hyperuricemia in hypertensive patients
Pharmacotherapy for mild hypertension
Pharmacotherapy for thyroid nodules
Pharyngeal instillation of surfactant before the first breath for prevention of morbidity and mortality in preterm infants at risk of respiratory distress syndrome
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures
Phenytoin for neuropathic pain and fibromyalgia in adults
Phlebotonics for haemorrhoids
Phonics training for English-speaking poor readers
Phosphate binders for preventing and treating bone disease in chronic kidney disease patients
Phosphodiasterase III inhibitors for chronic asthma
Phosphodiasterase IV inhibitors for chronic asthma
Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease
Phosphodiesterase inhibitors for lower urinary tract symptoms consistent with benign prostatic hyperplasia
Photodynamic therapy for recurrent head and neck cancer
Photodynamic therapy using 5-ALA versus porfimer sodium for Barrett's oesophagus
Photorefractive keratectomy (PRK) versus laser assisted in situ keratomileusis (LASIK) for hyperopia correction
Phyllanthus species for chronic hepatitis B virus infection
Phyllanthus species versus antiviral drugs for chronic hepatitis B virus infection
Physical and behavioural therapies and lifestyle modifications in the prevention of urinary incontinence in women.
Physical exercise training interventions for children and young adults during and after treatment for childhood cancer
Physical interventions for preventing stress fractures of the lower limbs
Physical methods for preventing deep vein thrombosis in stroke
Physical rehabilitation for older people in long-term care
Physical tests for shoulder impingements and local lesions of bursa, tendon or labrum that may accompany impingement
Physical therapy for Bell's palsy (idiopathic facial paralysis)
Physical therapy for vestibular migraine
Physical training for asthma
Physical training for McArdle disease
Physician anaesthetists versus non-physician providers of anaesthesia for surgical patients
Physiotherapy for ankylosing spondylitis
Physiotherapy versus placebo or no intervention in Parkinson's disease
Phytomedicines (medicines derived from plants) for sickle cell disease
Phytotherapy versus hormonal therapy for postmenopausal bone loss
Pilates for low-back pain
Pin site care for preventing infections associated with external bone fixators and pins
Pindolol augmentation for depression
Pioglitazone for people with impaired glucose tolerance or impaired fasting blood glucose
Piracetam for acute ischaemic stroke
Piracetam for dementia or cognitive impairment
Piracetam for fetal distress in labour
Pizotifen for recurrent migraine
Planned caesarean section for women with a twin pregnancy
Planned hospital birth versus planned home birth
Planned relaparotomy versus relaparotomy on demand for treatment of secondary peritonitis
Planned repeat Caesarean section at 39 weeks compared to vaginal birth after caesarean (VBAC)
Plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy
Plasma exchange for Guillain-Barr? syndrome
Platelet rich therapies for long bone healing in adults
Platelet rich therapies for musculoskeletal soft-tissue injuries
Platinum-based chemoradiation for head and neck cancer
Platinum-induced hearing loss after treatment for childhood cancer
Plugs for containing faecal incontinence
Pneumococcal vaccination during pregnancy for preventing infant infection
Pneumococcal vaccines for cystic fibrosis
Polyclonal anti-thymocyte globulins for the prophylaxis of graft-versus-host disease after allogeneic stem cell or bone marrow transplantation in adults
Polymer-based oral rehydration solution versus ORS ≤ 270 for acute watery diarrhoea
Polyunsaturated fatty acid supplementation in infancy for the prevention of allergy and food hypersensitivity
Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents
Polyunsaturated fatty acids (PUFAs) for children with specific learning disorders
Ponseti method for idiopathic congenital clubfoot in children
Population-based biomedical sexually transmitted infection control interventions for reducing HIV infection
Population-level interventions in government jurisdictions for dietary sodium reduction: differential effects by social and economic indicators on health outcomes related to high sodium intake
Position in the second stage of labour for women with epidural anaesthesia
Position in the second stage of labour for women without epidural anaesthesia
Positioning for acute respiratory distress in hospitalised infants and children
Positive end expiratory pressure for preterm infants requiring conventional mechanical ventilation for respiratory distress syndrome or bronchopulmonary dysplasia
Positive end-expiratory pressure (PEEP) during anaesthesia for the prevention of mortality and postoperative pulmonary complications
Positive pressure therapy for Ménière’s disease
Posterior discectomy for lumbar disc herniations
Post-exposure passive immunisation for preventing measles
Postoperative 5-Fluorouracil for glaucoma surgery
Postoperative adjuvant chemotherapy in rectal cancer operated for cure.
Postoperative bathing and showering to prevent wound complications
Postoperative tamoxifen for ductal carcinoma in situ
Post-operative therapy (splinting regimens) after metacarpophalangeal arthroplasty
Pre and post hospital Disease Management for Heart Failure
Pre-admission antibiotics for suspected cases of meningococcal disease
Prebiotics for preventing atopic eczema in infants
Prebiotics in infants for prevention of allergy
Pre-conception care and advice for women with diabetes
Preconception care for diabetic women for improving maternal and infant health
Preconception counselling as an influence on pregnancy planning behaviour in women with epilepsy
Predictors for the timing and intensity of anticoagulation therapy following central nervous system haemorrhage in patients with high thromboembolitic risk
Predictors of response to thiazolidinedione treatment of non-alcoholic fatty liver disease
Prednisolone for collagenous colitis
Pre-employment examinations for preventing occupational injury and disease in workers
Pre-emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant recipients
Pregabalin add-on for drug-resistant partial epilepsy
Pregabalin for chronic prostatitis
Pregabalin for essential tremor
Pregabalin monotherapy for epilepsy
Pre-hospital versus in-hospital thrombolysis for acute myocardial infarction
Pre-identification services, including assessment and diagnosis and early engagement, for racial and ethnic groups with schizophrenia
Prenatal education for congenital toxoplasmosis
Prenatal or postnatal allergen avoidance to prevent asthma
Preoperative alcohol cessation prior to elective surgery
Preoperative analgesics for additional pain relief in children and adolescents having dental treatment
Preoperative bathing or showering with skin antiseptics to prevent surgical site infection
Pre-operative biliary drainage for obstructive jaundice
Preoperative blood transfusions for sickle cell disease
Pre-operative chemoradiation for non-metastatic locally advanced rectal cancer
Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer
Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding
Preoperative hair removal to reduce surgical site infection
Preoperative inspiratory muscle training for postoperative pulmonary complications in adult patients undergoing cardiac and major abdominal surgery
Pre-operative nutrition support in patients undergoing gastrointestinal surgery
Preoperative physical exercise training for patients scheduled for major abdominal surgery
Preoperative physical therapy for elective cardiac surgery patients
Preoperative physical therapy for elective cardiac surgery patients
Preoperative skin antiseptics for preventing surgical wound infections after clean surgery
Preoperative statin therapy for patients undergoing cardiac surgery
Pre-operative traction for fractures of the proximal femur in adults
Pre-operative traction for hip fractures in adults
Preprostatectomy pelvic floor exercises to prevent urinary incontinence.
Pre-referral rectal artesunate for severe malaria
Pressure-relieving devices for treating heel pressure ulcers
Pressure-relieving interventions for treating diabetic foot ulcers
Pressurised-metered dose inhalers versus hand-held inhalers for the delivery of corticosteroids in chronic asthma
Pre-surgical orthopaedics (PSO) for infants with complete cleft lip and palate
Pre-treatment surgical para-aortic lymph node assessment in locally advanced cervical cancer
Preventative strategies to prevent foot ulcers in people with diabetes
Prevention and treatment of postpartum hypertension
Prevention of aminoglycoside-induced vestibular injury
Prevention of lymphoedema following surgery for breast cancer
Prevention of trismus induced by cancer therapies in head and neck cancer patients
Preventive interventions for postnatal psychosis
Primaquine for reducing Plasmodium falciparum transmission
Primary care based clinics for asthma
Primary care professionals providing non-urgent care in hospital emergency departments
Primary closure versus delayed closure for non bite traumatic wounds within 24 hours post injury
Primary prophylactic colony-stimulating factors for the prevention of chemotherapy-induced febrile neutropenia in breast cancer patients
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy
Primary surgery versus primary radiotherapy with or without chemotherapy for early adenocarcinoma of the uterine cervix
Printed educational materials: effects on professional practice and healthcare outcomes
Probiotic fermented milk or isolated probiotic bacteria for primary prevention of cardiovascular disease in adults
Probiotics (other than bifidobacterium infantis) for irritable bowel syndrome
Probiotics for fibromyalgia
Probiotics for idiopathic constipation in children
Probiotics for maintenance of remission in ulcerative colitis
Probiotics for non-alcoholic fatty liver disease and/or steatohepatitis
Probiotics for patients with hepatic encephalopathy
Probiotics for preventing acute upper respiratory tract infections
Probiotics for preventing atopic eczema in infants at high risk for the development of atopy
Probiotics for preventing gestational diabetes
Probiotics for prevention of necrotizing enterocolitis in preterm infants
Probiotics for the treatment of allergic rhinitis
Probiotics for treating established atopic eczema
Probiotics for vulvovaginal candidiasis in non-pregnant women
Problem solving skills for schizophrenia
Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections
Professionally-applied chemically-induced whitening of teeth in adults
Progabide add-on for refractory epilepsy
Progestagens and anti-progestagens for pain associated with endometriosis
Progesterone for acute traumatic brain injury
Progesterone for premenstrual syndrome
Progesterone or progestogen for threatened miscarriage
Progesterone receptor antagonists and progesterone receptor modulators for endometriosis
Progestin-only contraceptives: effects on weight
Progestogen for treating threatened miscarriage
Progestogen only versus combined oral contraceptive pills for fibroid related heavy menstrual bleeding
Progestogens or progestogen-releasing intrauterine systems for uterine fibroids
Progestogens with or without oestrogen for irregular uterine bleeding associated with anovulation
Progressive resistance training (PRT) for improved physical function in older adults
Prolonged retreatment with pegylated interferon plus ribavirin of chronic hepatitis C non-responders to interferon plus ribavirin
Prolonged therapy with progestagens and anti-progestagens for pain associated with endometriosis
Prolotherapy injections for chronic low back pain
Promoting the mental health of carers of people with dementia
Prompted voiding for urinary incontinence
Prompted voiding, habit retraining, and timed voiding for urianary incontinence in frail older persons
Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery
Prophylactic antibiotics to reduce morbidity and mortality in neonates with umbilical artery catheters
Prophylactic antibiotics to reduce morbidity and mortality in neonates with umbilical venous catheters
Prophylactic antibiotics to reduce morbidity and mortality in newborn infants with intercostal catheters
Prophylactic antibiotics to reduce morbidity and mortality in ventilated newborn infants
Prophylactic antibiotics to reduce the risk of urinary tract infections after urodynamic studies
Prophylactic anti-staphylococcal antibiotics for cystic fibrosis
Prophylactic chemotherapy for hydatidiform mole to prevent gestational trophoblastic neoplasia
Prophylactic corticosteroids for cardiopulmonary bypass in adults
Prophylactic drug management for febrile seizures in children
Prophylactic epidural blood patch and post-dural puncture headache
Prophylactic gastrojejunostomy for unresectable periampullary carcinoma
Prophylactic gastrostomy tubes for head and neck cancer
Prophylactic oral betamimetics for reducing preterm birth in women with a twin pregnancy
Prophylactic oral/topical non-absorbed antifungal agents to prevent invasive fungal infection in very low birth weight infants
Prophylactic phototherapy for preventing jaundice in preterm or low birth weight infants
Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell transplantation
Prophylactic systemic antifungal agents to prevent mortality and morbidity in very low birth weight infants
Prophylactic treatment of lymph node basins in lymph node metastases from auricular squamous cell carcinoma
Prophylactic versus selective blood transfusion for sickle cell disease in pregnancy
Prophylactic versus selective use of surfactant in preventing morbidity and mortality in preterm infants
Prophylactic versus therapeutic amnioinfusion for oligohydramnios in labour
Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period
Prophylaxis for venous thromboembolism during asparaginase therapy in patients treated for acute lymphoblastic leukemia
Prophylaxis of neutropenic sepsis in children and young people (aged under 18) and adults (aged 18 and older) diagnosed with lymphoma
Propionyl-L-carnitine for intermittent claudication
Propofol and ketamine in combination versus ketamine or propofol alone for procedural sedation in children outside of the operating room
Propofol for procedural sedation/anaesthesia in neonates
Propofol for sedation during colonoscopy
Propofol versus placebo for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Propofol versus thiopental sodium for the treatment of refractory status epilepticus
Prostaglandin E1 for preventing the progression of diabetic kidney disease
Prostaglandin E1 for preventing the progression of diabetic kidney disease
Prostaglandins before caesarean section for preventing neonatal respiratory distress; Surgery, anaesthesia, perioperative and critical care
Prostaglandins for adult liver transplanted patients
Prostaglandins for management of retained placenta
Prostaglandins for preventing postpartum haemorrhage
Prostanoids for intermittent claudication
Prosthetic treatment after maxillary and mandibular reconstruction in patients with head and neck cancer
Proton pump inhibitors in acute upper gastro-intestinal bleeding
Proximal sealing for managing dental decay in primary and permanent teeth
Psychodynamic psychotherapy for children with depression
Psychological and educational interventions for atopic eczema in children
Psychological and educational interventions for preventing depression in children and adolescents
Psychological and pharmacological interventions for depression in patients with coronary artery disease
Psychological and pharmacological interventions for depression in patients with diabetes mellitus and depression
Psychological and psychosocial interventions for people with schizophrenia from specific ethnic groups
Psychological and/or educational interventions for reducing alcohol consumption in pregnant women and women planning pregnancy
Psychological interventions for acute pain after open heart surgery
Psychological interventions for adults who have sexually offended or are at risk of offending
Psychological interventions for adults with asthma
Psychological interventions for coronary heart disease
Psychological interventions for improved quality of life in vitiligo
Psychological interventions for parents of children and adolescents with chronic illness
Psychological interventions for people with hemophilia
Psychological interventions for people with histrionic personality disorder
Psychological interventions for people with narcissistic personality disorder
Psychological interventions for post-traumatic stress disorder and comorbid substance use disorder
Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy
Psychological interventions for treating chronic pelvic pain in women
Psychological interventions for treatment of inflammatory bowel disease
Psychological therapies for irritable bowel syndrome
Psychological therapies for pathological and problem gambling
Psychological therapies for people with borderline personality disorder
Psychological therapies for sickle cell disease and pain
Psychological therapies for thalassaemia
Psychological therapies for the management of chronic and recurrent pain in children and adolescents
Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents
Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents
Psychological treatments for epilepsy
Psychologically mediated effects of the physical healthcare environment on work-related outcomes of healthcare personnel
Psychosocial and cultural interventions for reducing alcohol consumption during lactation
Psychosocial and psychological interventions for preventing postpartum depression
Psychosocial interventions for adults who were sexually abused as children
Psychosocial interventions for adults who were sexually abused as children
Psychosocial interventions for improving quality of life outcomes in adults undergoing strabismus surgery
Psychosocial interventions for informal caregivers of people living with cancer
Psychosocial interventions for premature ejaculation
Psychosocial interventions for prevention of depression in older people
Psychosocial interventions for psoriasis
Psychosocial interventions for reducing antipsychotic medication in care home residents
Psychosocial interventions for the management of chronic orofacial pain
Psychosocial interventions to improve quality of life and emotional wellbeing for recently diagnosed cancer patients
Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users
Psychostimulants for depression
Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy
Psychotherapeutic treatments for older depressed people
Psychotherapy for depression in children and adolescents
Public and professional education for continence issues
Public release of performance data in changing the behaviour of healthcare consumers, professionals or organisations
Pulmonary artery catheters for adult patients in intensive care
Pulmonary artery flow catheters for directing management in pre-eclampsia
Pulsed antibiotic regimen versus continuous course for Lyme disease
Pulsed dye laser treatment for acne
Punctal occlusion for dry eye syndrome
Purine analogues plus cyclophosphamide versus purine analogues alone for first-line therapy of patients with chronic lymphocytic leukaemia
Push versus gravity for intermittent bolus gavage tube feeding of premature and low birth weight infants
PUVA (oral psoralens with UVA) as a monotherapy for repigmentation in vitiligo
Pycnogenol for the treatment of chronic disorders
Pyridoxal 5 phosphate for neuroleptic-induced tardive dyskinesia
Qigong for the primary prevention of cardiovascular disease
Quadriphasic versus monophasic oral contraceptives for contraception
Quality of life after excisional surgery with drainage and ablation of ovarian endometriomata
Quality of life after liver transplantation in female recipients
Quality of life after liver transplantation in hepatitis C virus-infected recipients
Quality of life after rectal resection for cancer, with or without permanent colostomy.
Quantitative versus qualitative cultures of respiratory secretions for clinical outcomes in patients with ventilator-associated pneumonia
Quinine for muscle cramps
Radial optic neurotomy for central retinal vein occlusion
Radiation dose on tumor control and morbidity in the treatment of prostate cancer by 3D-CRT
Radiation therapy for diffuse brainstem glioma in children and young adults
Radiofrequency ablation for Barrett's oesophagus and Barrett's dysplasia
Radiofrequency ablation in the treatment of liver metastases from colorectal cancer
Radiofrequency ablation versus percutaneous alcohol versus acetic acid injection for hepatocelullar carcinoma
Radiofrequency ablation versus surgical resection for oligometastatic hepatic metastases of colorectal cancer
Radiofrequency ablation versus surgical resection for resectable hepatic metastases of colorectal cancer
Radiofrequency ablation versus surveillance for reduction of risk of progression to adenocarcinoma in Barrett's oesophagus
Radiofrequency catheter ablation of the pulmonary veins for treatment of atrial fibrillation
Radiofrequency cold ablation for respiratory papillomatosis
Radiofrequency thermal ablation versus other interventions for hepatocellular carcinoma
Radioiodine therapy versus anti-thyroid medications for Graves' disease
Radioiodine treatment for paediatric Graves' disease
Radiological embolisation versus surgery for pelvic congestion
Radionuclide therapy combined with liver resection for neuroendocrine tumours in patients with resectable liver metastases
Radiosurgery for acoustic neuroma
Radiotherapy and chemoradiation after surgery for early cervical cancer
Radiotherapy to Head and Neck cancer patients and radiation-induced hypothyroidism : the dose / volume relationship
Raised body temperature for Lyme disease
Ranibizumab compared to bevacizumab (clinical effectiveness and cost effectiveness) in the treatment of exudative age-related macular degeneration (AMD)
Rapid antigen detection test for group A streptococcus in children with pharyngitis
Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries
Rapid palatal expansion effects on nasal airway dimensions as measured by acoustic rhinometry
Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department
Rate of adverse events in dialysis patients receiving interferon therapy for chronic hepatitis C versus those not on antiviral therapy
Rate of serious adverse events in antiviral treatment for chronic hepatitis C in patients with HIV
Rate of serious adverse events in small-incision or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis
Rates of ectopic pregnancy in women with endometriosis after long term pituitary down-regulation using GnRH agonists prior to in vitro fertilisation
Reboxetine for depression
Reboxetine for depression
Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia
Recombinant factor VIIa to decrease blood loss and blood transfusion requirements for liver resection
Recombinant growth hormone therapy for X-linked hypophosphatemia in children
Recombinant human growth hormone for treating burns and donor sites
Recombinant versus urinary gonadotrophin for ovarian stimulation in assisted reproductive technology cycles
Recompression and adjunctive therapy for decompression illness
Reconstructive Techniques After Rectal Resection for Rectal Cancer
Rectal 5-aminosalicylic acid for maintenance of remission in ulcerative colitis
Red blood cell salvage during Caesarean section for reduction of non-autologous blood transfusion
Red blood cell transfusion for people undergoing hip fracture surgery
Red cell transfusion for acute upper gastrointestinal haemorrhage
Red cell transfusion management for patients undergoing cardiac surgery for congenital heart disease
Red flags to screen for malignancy in patients with low-back pain
Red flags to screen for vertebral fracture in patients presenting with low-back pain
Reduced dietary salt for the prevention of cardiovascular disease
Reduced or modified dietary fat for preventing cardiovascular disease
Reduction of dialysate temperature for intradialytic hypotension during haemodialysis
Reduction of the number of fetuses for women with a multiple pregnancy
Reduction versus abrupt cessation in smokers who want to quit
Regimens of fetal surveillance for impaired fetal growth
Regional analgesia for improvement of long-term functional outcome after elective large joint replacement
Regional versus general anaesthesia for caesarean section
Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction
Regular long-term red blood cell transfusions for managing chronic chest complications in sickle cell disease
Regular toileting for urinary incontinence
Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events
Regular treatment with salmeterol and inhaled steroids for chronic asthma: serious adverse events
Regular treatment with salmeterol for chronic asthma: serious adverse events
Regular use of prophylactic medication for asthma
Rehabilitation exercises for chronic vertigo in primary care
Rehabilitation for ankle fractures in adults
Rehabilitation for ankle fractures in adults
Rehabilitation for hamstring injuries
Rehabilitation for hamstring injuries
Rehabilitation interventions for foot drop in neuromuscular disease
Rehabilitation interventions to ameliorate side effects in patients treated with chemoradiotherapy for advanced head and neck cancer
Rehabilitation programmes for schizophrenia
Rehabilitative exercises after lumbar disc surgery
Rehabilitative treatment of aphasia
Relationship between treatment and clinical outcomes in antiviral treatment for chronic hepatitis C in patients with HIV
Relative effectiveness of combined oral contraceptive pills in women compared to other acne treatments
Relaxation for depression
Relaxation techniques for pain management in labour
Relaxation therapy for preventing and treating preterm labour
Relaxin for cervical ripening and induction of labour
Relaxin for preventing preterm birth in threatened preterm labour
Relevance of genospecies or strain of Borellia in antibiotic treatment of Lyme disease
Relevance of patient weight in choosing an appropriate antibiotic regimen for Lyme disease
Remediating buildings damaged by dampness and mould for preventing or reducing respiratory tract symptoms, infections and asthma
Reminiscence groups for people with dementia and their family care-givers: pragmatic 8-centre trial of joint reminiscence and maintenance versus usual treatment
Remote and web 2.0 interventions for promoting physical activity
Remote ischaemic preconditioning versus no remote ischaemic preconditioning for vascular and endovascular surgical procedures
Removal of nail polish and finger rings to prevent surgical infection
Repeated use of pre- and postcoital hormonal contraception for prevention of pregnancy
Repetitive transcranial magnetic stimulation for the treatment of amyotrophic lateral sclerosis or motor neuron disease
Repetitive transcranial magnetic stimulation for tinnitus
Replacement of estrogens and progestins to prevent morbidity and mortality in preterm infants
Repositioning for pressure ulcer prevention in adults
Repositioning for treating pressure ulcers
Resection and biopsy for patients with gliomas for survival and quality of life
Resection versus no intervention or other surgical interventions for colorectal cancer liver metastases
Resection versus other treatments for locally advanced pancreatic cancer
Resistance exercise for walking mobility in people with multiple sclerosis
Respiratory function monitoring to reduce mortality and morbidity in newborn infants receiving resuscitation
Respiratory therapy for removing bronchial secretions in mechanically ventilated adult patients
Rest for Lyme disease
Restorative justice conferencing for reducing recidivism in young offenders (aged 7 to 21)
Restricted elimination diets for attention deficit-hyperactivity disorder (ADHD)
Restriction of oral intake of water for aspiration lung disease in children
Resveratrol and derivatives for rosacea
Rheum officinale (a traditional Chinese medicine) for chronic kidney disease
Rifaximin for irritable bowel syndrome
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
Risk factor modification to prevent acute otitis media
Risk of community-acquired pneumonia following proton pump inhibitor use
Risk of minor incontinence following anal fistula surgery with abscess drainage
Risk of osteporosis or osteopenia with depot medroxyprogesterone acetate (DMPA) in women with IBD
Risk of postoperative complications in patients with inflammatory bowel disease undergoing abdominal surgery after treatment with steroids or biological agents
Risk of progressive multifocal leukoencephalopathy after natalizumab treatment of multiple sclerosis
Risk of visual field defects in patients with refractory partial epilepsy taking vigabatrin
Risk scoring systems for predicting preterm birth with the aim of reducing associated adverse outcomes
Risk stratification for venous thromboembolic disease following elective spine surgery
Risperidone for cannabis cravings or use in people with psychosis and coexisting substance misuse
Risperidone for disruptive behaviour disorders in children with intellectual disabilities
Risperidone versus olanzapine for schizophrenia
Rituximab for relapsing-remitting multiple sclerosis
Rituximab, ofatumumab and other monoclonal anti-CD20 antibodies for chronic lymphocytic leukaemia
Robot assistant versus human or another robot assistant in patients undergoing laparoscopic cholecystectomy
Robotic assisted surgery for gynaecological cancer
Robotic surgery for benign gynaecological disease
Role of antibiotics in facilitating post-tonsillectomy recovery
Role of antimalarial therapies in the exacerbation of psoriasis
Role of bismuth subgallate-epinephrine (BSE) paste as a hemostatic in adenotonsillectomies
Role of chemotherapy additional to high-dose methotrexate for primary central nervous system lymphoma (PCNSL)
Role of diet in triggering atopic eczema
Role of early antibiotic treatment for Lyme disease in preventing persistent infection
Role of genetic factors in determining efficacy of clobazam and other anti-epileptic drugs in patients with refractory epilepsy
Role of ribavirin in reducing bone mineral density in chronic hepatitis C patients
Rotarix versus RotaTeq for the prevention of rotavirus diarrhoea
Rotavirus vaccination for the prevention of all-cause diarrhoea
Rotavirus vaccination for the prevention of rotavirus diarrheoa in HIV-positive children
Rotavirus vaccination for the prevention of rotavirus diarrheoa in malnorished children
Rotavirus vaccination for the prevention of rotavirus diarrheoa in preterm infants
Routine and selective invasive strategies for acute coronary syndrome
Routine follow-up or symptom-led follow-up for people with lung cancer.
Routine neonatal circumcision for the prevention of urinary tract infections in infancy
Routine oro/nasopharyngeal suction versus no suction in the delivery room
Routine preoperative medical testing for cataract surgery
Routine vaginal examinations for assessing progress of labour to improve outcomes for women and babies at term
Routine vitamin A supplementation for the prevention of blindness due to measles infection in children
Rubber band ligation versus excisional haemorrhoidectomy for haemorrhoids
Rubber dam isolation for restorative treatment in dental patients
Rutosides for prevention of post-thrombotic syndrome
Rutosides for treatment of post-thrombotic syndrome
Sacral nerve stimulation for urinary incontinence and voiding dysfunction in adults
S–adenosyl–L–methionine for alcoholic liver diseases
S-Adenosylmethionine (SAMe) for osteoarthritis of the knee or hip
Safe perioperative window of anticoagulation after spine surgery
Safety of laterally placed and laterally directed multi-needle core biopsy for diagnosing prostate cancer
Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis)
Safety of regular formoterol or salmeterol in adults with asthma: an overview of Cochrane reviews
Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews
Safety of steroids in Lyme disease patients
Safety of sulfasalazine for autoimmune inflammation if active Lyme disease is present.
Safety of swimming in patients with chronic heart failure
Safety of topical corticosteroids in pregnancy
Safety of wet-wrap dressings with diluted topical corticosteroids, in particular 'new generation' topical corticosteroids versus established corticosteroids
Safety/tolerability and patient acceptability of low dose antipsychotic medication for people with schizophrenia
Saline irrigation for the management of skin extravasation injury in neonates
Saliva substitutes for the treatment of radiation-induced xerostomia
Salt baths for atopic eczema
Sanitary disposal of human excreta for the prevention of diarrhoea
Sapropterin dihydrochloride for phenylketonuria
Sargramostim (GM-CSF) for induction of remission in Crohn's disease
Scalpel versus electrosurgery for abdominal incisions
Scalpel versus no-scalpel incision for vasectomy
'Scared Straight' and other juvenile awareness programs for preventing juvenile delinquency
School based education programmes for the prevention of unintentional injuries in children and young people
School policies for preventing smoking among young people
School-based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18
School–based prevention for illicit drugs' use
School-based programmes for preventing smoking
Sclerotherapy for lower limb telangiectasias
Scopolamine for treating motion sickness
Screening and decontamination of contacts of patients with Panton Valentine leukocidin associated Staphylococcus aureus infection
Screening for colorectal cancer using the faecal occult blood test, Hemoccult
Screening for prevention of optic nerve damage due to chronic open angle glaucoma
Screening for prostate cancer
Screening for testicular cancer
Screening programmes for developmental dysplasia of the hip in newborn infants
Screening with urinary dipsticks for reducing morbidity and mortality
Screening women for intimate partner violence in healthcare settings
Sealants for preventing dental decay in the permanent teeth
Sealing procedures for preterm prelabour rupture of membranes
Second or third additional chemotherapy drug for non-small cell lung cancer in patients with advanced disease
Second trimester serum tests for Down's Syndrome screening
Secondary bone grafting for alveolar cleft in children with cleft lip or cleft lip and palate
Second-generation antidepressants for seasonal affective disorder
Second-generation antipsychotics for anxiety disorders
Second-generation antipsychotics for major depressive disorder and dysthymia
Second-generation antipsychotics for obsessive compulsive disorder
Second-line, post-docetaxel therapy for advanced, androgen deprivation-refractory prostate cancer
Sedation of children undergoing dental treatment
Sedation versus general anaesthesia for provision of dental treatment in under 18 year olds
Sedative techniques for endoscopic retrograde cholangiopancreatography
Segmental fasciectomy for Dupuytren’s contractures of the hand
Selective computed tomography (CT) versus routine thoracoabdominal CT for high-energy blunt trauma patients
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas
Selective internal radiation therapy in combination with chemotherapy as front-line therapy for liver metastases from colorectal cancer
Selective noradrenaline reuptake inhibitors for schizophrenia
Selective serotonin reuptake inhibitors (SSRIs) for depressive disorders in children and adolescents
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery
Selective serotonin reuptake inhibitors (SSRIs) for the treatment of moderate and severe depression in adults with autism
Selective serotonin reuptake inhibitors (SSRIs) in patients with depression and coronary heart disease
Selenium for preventing cancer
Selenium supplementation during pregnancy for improving maternal and newborn outcomes
Selenium supplementation for critically ill adults
Selenium supplementation for Hashimoto's thyroiditis
Selenium supplementation for the primary prevention of cardiovascular disease
Selenium supplementation to prevent short-term morbidity in preterm neonates
Self-expanding metal stent insertion versus non-stent therapy or combination non-stent and stent therapy for dysphagia in oesophageal cancer
Self-management education for cystic fibrosis
Self-management programs for quality of life in people with stroke
Self-monitoring for improving control of blood pressure in patients with hypertension
Self-monitoring of blood glucose in patients with type 2 diabetes mellitus who are not using insulin
Semi-recumbent position versus supine position for the prevention of ventilator-associated pneumonia in adults requiring mechanical ventilation
Semont manuoevre for posterior canal benign paroxysmal positional vertigo
Sensory environment on health-related outcomes of hospital patients
Sensory stimulation for brain injured individuals in coma or vegetative state
Sentinel lymph node biopsy followed by lymph node dissection for early cutaneous melanoma
Sentinel lymph node biopsy for the diagnosis of lymph node involvement in oral/oropharyngeal squamous cell carcinoma
Sentinel node assessment for diagnosis of groin lymph node involvement in vulvar cancer
Separate care for new mother and infant versus rooming-in for increasing the duration of breastfeeding
Septal surgery for nasal airflow
Sequencing of chemotherapy and radiotherapy for early breast cancer
Serenoa repens for benign prostatic hyperplasia
Serious adverse infant and long-term childhood outcomes with using anti-clotting medications during pregnancy
Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia syndrome
Sertraline for depression
Sertraline versus other antidepressive agents for depression
Service brokerage for improving health outcomes in ex-prisoners
Services for reducing duration of hospital care for acute stroke patients
Sevoflurane versus placebo for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Shengmai (a traditional Chinese herbal medicine) for heart failure
Short acting beta2-agonists for exercise induced asthma
Short and long term benefits of methylphenidate for adult male prison inmates with attention deficit-hyperactivity disorder (ADHD)
Short and long term effects of tibolone in postmenopausal women
Short term post-operative complications after pre-operative infliximab treatment in ulcerative colitis
Short-course versus prolonged-course antibiotic therapy for hospital-acquired pneumonia in critically ill adults
Short-term late-generation antibiotics versus longer term penicillin for acute streptococcal pharyngitis in children
Should all sleep apnoea patients with heart disease be treated with either drugs, oral appliances, upper airway surgery or continuous positive airway pressure (CPAP), regardless of daytime sleepiness in order to prevent further cardiovascular complications?
Should antibiotics be used orally, topically, or in combination with other treatments for acne?
Should antihistamines be used to treat anaphylaxis?
Should asthma be monitored more carefully/differently in pregnancy when compared with other adult situations?
Should GPs be allowed to manage epilepsy medication dosage?
Should GPs take an active role in the treatment of people with epilepsy?
Should I be concerned that the steroid I take for my asthma via an inhaler will cause osteoporosis and increased body weight in the long run?
Should I be more concerned about adverse effects from antipsychotic drugs with late onset of psychosis?
Should inhalers be used in people with asthma while they have a cold?
Should injections sites be varied when injecting insulin for diabetes?
Should interventions to help people quit smokeless tobacco differ from those used for smoked tobacco?
Should men who had prostatitis or epididymytis be screened for prostate cancer?
Should patients monitor their PSA history?
Should people be discharged from A&E without somebody with a specialist interest in epilepsy reviewing their treatments?
Should potentially toxic treatments be used on a rotational basis for severe atopic eczema?
Should prophylactic antibiotics be prescribed routinely following ingrown toe nail surgery?
Should retinal assessment during pregnancy be offered to women diagnosed with gestational diabetes who are suspected of having pre-existing diabetes?
Should statins be started in children with Type 1 diabetes?
Should the effect of tinnitus on a person's mental health and well-being be assessed by a healthcare professional?
Should the nil-by-mouth rules exclude epilepsy medications?
Should treatment for heart failure with preserved ejection fraction differ from that for heart failure with reduced ejection fraction?
Should we tailor synthetic insulin doses to match pancreatic secretion to gain better symptom control
Should women with severe pre-eclampsia in the community, or in a primary care setting, be given magnesium sulphate before transfer to hospital?
Shouldice technique versus other open techniques for inguinal hernia repair
Sildenafil citrate for erectile dysfunction in patients with multiple sclerosis
Sildenafil for pulmonary hypertension in neonates
Sildenafil for pulmonary hypertension in neonates
Silver acetate for smoking cessation
Simple behavioural interventions for nocturnal enuresis in children
Simple urethral dilatation, endoscopic urethrotomy, and urethroplasty for urethral stricture disease in adult men
Simulator based rehabilitation for chronic dizziness
Single crowns versus conventional fillings for the restoration of root filled teeth
Single dose antibiotics for treating urinary tract infection in children
Single dose intravenous propacetamol or intravenous paracetamol for postoperative pain
Single dose oral celecoxib for acute postoperative pain in adults
Single dose oral fenoprofen for acute postoperative pain in adults
Single dose oral ibuprofen plus codeine for acute postoperative pain in adults
Single dose oral ibuprofen plus codeine for acute postoperative pain in adults
Single dose oral ibuprofen plus oxycodone for acute postoperative pain in adults
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain
Single dose oral mefenamic acid for acute postoperative pain in adults
Single incision versus conventional multi-incision appendicectomy for suspected appendicitis
Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients
Single inhalers containing corticosteroid and long-acting bronchodilator for chronic asthma in adults and children
Single layer versus double layer suture anastomosis of the gastrointestinal tract
Single versus combination intravenous antibiotic therapy for people with cystic fibrosis
Single-agent interleukin-2 in the treatment of metastatic melanoma
Single-use non-coated versus single-use hydrophilic versus single-use gel reservoir versus reusable non-coated catheters for patients performing intermittent self-catheterisation
Sinomenine for rheumatoid arthritis
Skin antisepsis during catheter insertion for reducing central venous catheter related infections
Skin grafting for venous leg ulcers
Skin patch and vaginal ring versus combined oral contraceptives for contraception
Skin preparation for preventing infection following caesarean section
Skin preparation with alcohol versus alcohol followed by any antiseptic for preventing bacteraemia or contamination of blood for transfusion
Sleep positioning for children with cerebral palsy
Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants
Slow-release oral morphine as maintenance therapy for opioid dependence
Slum upgrading strategies involving physical environment and infrastructure interventions and their effects on health and socio-economic outcomes
Slum upgrading strategies involving physical environment and infrastructure interventions and their effects on health and socio-economic outcomes
Smartphone and tablet self-management apps for asthma
Smokeless tobacco cessation services for people of South Asian origin?
Smoking cessation advice for people with serious mental illness
Smoking cessation and nicotine replacement therapy in COPD patients.
Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD)
Social skills training for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years
Sodium bicarbonate supplements for treating acute kidney injury
Sodium channel blockers for cystic fibrosis
Sodium channel blockers for neuroprotection in multiple sclerosis
Somatostatin analogues for carcinoid syndrome
Somatostatin analogues for pancreatic surgery
Somatostatin analogues for treatment of enterocutaneous fistula
Sonothrombolysis for acute ischaemic stroke
Sorafenib for cholangiocellular carcinoma
Sound therapy for tinnitus
Special diets for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Specialised antenatal clinics for women with a multiple pregnancy for improving maternal and infant outcomes
Specialised antenatal clinics for women with a pregnancy at high risk of preterm birth (excluding multiple pregnancy) to improve maternal and infant outcomes
Specialised clothing for reducing or preventing atopic eczema
Specialist continence clinics in the community.
Specialist interventions for homeless people with severe mental illness
Specialist nursing interventions for inflammatory bowel disease
Specific adverse drug reactions resulting from the combination of methotrexate with phototherapy for psoriasis
Spectral entropy monitoring for adults and children undergoing general anaesthesia
Speech and language therapy for aphasia following stroke
Speech and language therapy for aphasia following stroke
Speech and language therapy for dysarthria
Speech and language therapy for receptive language difficulties in children with primary speech and language delay
Speech and language therapy to improve the communication skills of children with cerebral palsy
Speech and language therapy versus placebo or no intervention for speech problems in Parkinson's disease
Speech and language therapy versus placebo or no intervention for speech problems in Parkinson's disease
Speleotherapy for asthma
Sphenopalatine artery ligation for epistaxis
Sphincterotomy for biliary sphincter of Oddi dysfunction
Spinal cord stimulation for cancer-related pain in adults
Spinal cord stimulation for chronic pain of neuropathic or ischaemic origin
Spinal cord stimulation for non-reconstructable chronic critical leg ischaemia
Spinal endoscopic adhesiolysis for post lumbar surgery syndrome
Spinal manipulation for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Spinal manipulative therapy for acute low-back pain
Spinal manipulative therapy for chronic low-back pain
Spiritual and religious interventions for well-being of adults in the terminal phase of disease
Spironolactone for treatment of acne in women
Spironolactone in diabetic nephropathy
Splinting for carpal tunnel syndrome
Sponge versus diaphragm for contraception
St John's Wort for Depression
St John's wort for major depression
Stability after bilateral sagittal split osteotomy advancement surgery with rigid internal fixation
Stainless-steel alloy versus nickel-titanium alloy endoscopic palliative biliary stents for obstructing pancreatic carcinoma
Standard home alarm clock for nocturnal enuresis
Standard versus biofilm antimicrobial susceptibility testing to guide antibiotic therapy in cystic fibrosis
Standard versus modified postural drainage in infants and young children with cystic fibrosis
Stapled versus handsewn methods for colorectal anastomosis surgery
Staples versus sutures for closing leg wounds after vein graft harvesting for coronary artery bypass surgery.
Starting dose of levothyroxine for the treatment of congenital hypothyroidism
Statins for acute coronary syndrome
Statins for acute ischemic stroke
Statins for age-related macular degeneration
Statins for chronic heart failure (CHF)
Statins for multiple sclerosis
Statins for primary prevention of venous thromboembolism
Statins for the primary prevention of cardiovascular disease
Statins for women with polycystic ovary syndrome not actively trying to conceive
Statins to prevent melanoma and non melanoma skin cancer.
Stem cell transplantation for high risk acute lymphoblastic leukaemia in paediatric patients in first remission
Stem cell transplantation for ischemic stroke
Stem cell treatment for acute myocardial infarction
Stent graft types for endovascular repair of abdominal aortic aneurysms
Stent graft types for endovascular repair of thoracic aortic aneurysms
Stent placement versus surgery for coarctation of the thoracic aorta
Stereotactic radiosurgery for acoustic neuroma
Steroid drops for otitis externa
Steroid hormones for contraception in men
Steroid hormones for contraception in women with sickle cell disease
Steroid or other pharmacological treatments for headache prophylaxis for people with medication overuse headaches when withdrawing from medication
Steroid sex hormones for lower limb atherosclerosis
Steroidal contraceptives and bone fractures in women: evidence from observational studies
Steroidal contraceptives and bone fractures in women: evidence from observational studies
Steroidal contraceptives: effect on carbohydrate metabolism in women without diabetes mellitus
Steroid-eluting sinus stents for improving symptoms in chronic rhinosinusitis patients undergoing functional endoscopic sinus surgery
Steroids for acute spinal cord injury
Steroids for improving recovery following tonsillectomy in children
Steroids for Lyme disease
Steroids in the treatment of vestibular neuronitis
Stiripentol for focal refractory epilepsy
Stiripentol for treating difficult seizures other than in SMEI
Strategies for communicating contraceptive effectiveness
Strategies for improving the acceptability and acceptance of the copper intrauterine device
Strategies for the withdrawal of nasal continuous positive airway pressure (NCPAP) in preterm infants
Strategies of testing for syphilis during pregnancy
Strategies to increase participant recruitment to research studies by healthcare professionals
Stretch for the treatment and prevention of contractures
Structured psoriasis-focused self-management programmes
Structured treatment interruptions (STI) in chronic suppressed HIV infection in adults
Subcutaneous closure versus no subcutaneous closure after non-obstetric surgical procedures
Subcutaneous versus intravenous erythropoietin for long-term dialysis patients
Subintimal angioplasty for chronic lower limb arterial occlusion
Sublingual immunotherapy for treating allergic conjunctivitis
Subsidising artemisinin-based combination therapies supplied to the private sector: impact on use, availability, price and market share
Sucrose for analgesia in newborn infants undergoing painful procedures
Suction blister grafts for repigmentation in vitiligo
Suction versus no suction for chest drain management
Sulphasalazine for psoriasis
Sulphonylurea monotherapy for patients with type 2 diabetes mellitus
Sulpiride dose for schizophrenia
Sulthiame add-on therapy for epilepsy
Sulthiame monotherapy for epilepsy
Sultopride for schizophrenia.
Sumatriptan (intranasal route of administration) for acute migraine attacks in adults
Sumatriptan (oral route of administration) for acute migraine attacks in adults
Sumatriptan (rectal route of administration) for acute migraine attacks in adults
Sumatriptan (subcutaneous route of administration) for acute migraine attacks in adults
Sun-protective behaviors and reduced Vitamin D levels, with increases in diseases hypotheszied to be affected by Vitamin D
Supplemental perioperative steroids for surgical patients with adrenal insufficiency
Supplementary pelvic floor exercises with electromyographic or manometric biofeedback.
Supplementation with long chain polyunsaturated fatty acids (LCPUFA) to breastfeeding mothers for improving child growth and development
Support for healthy breastfeeding mothers with healthy term babies
Support surfaces for treating pressure ulcers
Supportive interventions for enhancing dietary intake in malnourished or nutritionally at-risk adults
Supportive therapy for schizophrenia
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in obese patients
Surfactant for bacterial pneumonia in late preterm and term infants
Surfactant for pulmonary haemorrhage in neonates
Surfactant therapy for bronchiolitis in critically ill infants
Surgery for acute fractures or non-union of the third middle of the clavicle
Surgery for cataracts in people with age-related macular degeneration
Surgery for cervical radiculopathy and myelopathy
Surgery for cervical radiculopathy or myelopathy
Surgery for chronically discharging ears with underlying eardrum perforations
Surgery for congenital choanal atresia
Surgery for Dupuytren's contractures of the fingers
Surgery for lateral elbow pain
Surgery for long-term resistant epilepsy
Surgery for lumbar disc prolapse
Surgery for Ménière's disease
Surgery for rotator cuff disease
Surgery for scoliosis in Duchenne muscular dystrophy
Surgery for small asymptomatic abdominal aortic aneurysms
Surgery for stress urinary incontinence due to presumed sphincter deficiency after prostate surgery
Surgery for thumb osteoarthritis
Surgery for trigger finger
Surgery for tympanic membrane retraction pockets
Surgery for ulcerative colitis: Outcomes in low volume hospitals versus high volume hospitals
Surgery for vocal cord paralysis and paresis
Surgery or embolization for varicoceles in subfertile men
Surgery plus adjuvant radiotherapy versus surgery alone for stage II endometrial cancer
Surgery using LARS techniques versus proton pump inhibitors alone for prevention of adenocarcinoma in Barrett's oesophagus
Surgery using LARS techniques versus proton pump inhibitors alone for prevention of Barrett's oesophagus
Surgery using LARS techniques versus proton pump inhibitors alone for regression of Barrett's oesophagus
Surgery versus conservative treatment for odontoid fractures
Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus
Surgery versus radical endotherapies for early cancer and high-grade dysplasia in Barrett's oesophagus
Surgery versus surveillance for asymptomatic (mild) primary hyperparathyroidism in adults 50 years or older
Surgery, such as bladder augmentation, for intractible incontinence
Surgical compared with medical management of ectopic pregnancy
Surgical cytoreduction for recurrent epithelial ovarian cancer
Surgical decompression for cerebral oedema in acute ischaemic stroke
Surgical fixation methods for tibial plateau fractures
Surgical interruption of pelvic nerve pathways for primary and secondary dysmenorrhoea
Surgical interventions for adults with anterior shoulder instability
Surgical interventions for diaphyseal fractures of the radius and ulna in children
Surgical interventions for nasal polyps
Surgical interventions for nystagmus developing in the first year of life
Surgical interventions for pharyngeal pouch
Surgical interventions for the early management of Bell's palsy
Surgical interventions for treating chronic pelvic pain in women
Surgical interventions for treating distal humeral fractures in adults
Surgical interventions for treating distal humeral fractures in adults
Surgical interventions for treating distal tibial metaphyseal fractures in adults
Surgical interventions for treating extra-articular fractures of the second, third, fourth or fifth metacarpals in adults
Surgical interventions for treating fractures of the olecranon in adults
Surgical management for upper urinary tract transitional cell carcinoma
Surgical management of pelvic organ prolapse in women
Surgical orbital decompression for thyroid eye disease
Surgical removal versus retention for the management of asymptomatic impacted wisdom teeth
Surgical repair of spontaneous perineal tears that occur during childbirth versus no intervention
Surgical resection and whole brain radiation therapy versus whole brain radiation therapy alone for single brain metastases
Surgical resection versus non-surgical treatment for hepatic node positive patients with colorectal liver metastases
Surgical techniques other than Botox injection for spasmodic dysphonia
Surgical treatment of fibroids for subfertility
Surgical versus conservative interventions for displaced intra-articular calcaneal fractures
Surgical versus conservative interventions for treating acute scaphoid fractures in adults
Surgical versus conservative interventions for treating ankle fractures in adults
Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants
Surgical versus non-surgical interventions for flail chest
Surgical versus non-surgical interventions for treating humeral shaft fractures in adults
Surgical versus non-surgical interventions for treating patellar dislocation
Surgical versus non-surgical interventions for vocal cord nodules
Surgical versus non-surgical interventions for vocal cord nodules
Surgical versus non-surgical management of abdominal injury
Surgical versus non-surgical treatment for lumbar spinal stenosis
Survival and quality of life following treatment after first and subsequent relapse central nervous system tumours
Suturing versus alternative closure techniques for repair of episiotomy or second degree perineal tears
Swallowing outcomes after radiotherapy for head and neck cancer
Swapping or sharing of audio signals between bilaterally fitted hearing aids
Sweet potato for type 2 diabetes mellitus
Sweet tasting solutions for reduction of needle-related procedural pain in children aged one to 16 years
Sweet-tasting solutions for needle-related procedural pain in infants one month to one year of age
Swimming training for asthma in children and adolescents aged 18 years and under
Symphysial fundal height (SFH) measurement in pregnancy for detecting abnormal fetal growth
Symphysiotomy for feto-pelvic disproportion
Symptom based plans for the care of people with asthma – which ones and are they the same for all groups?
Symptomatic treatment of the cough in whooping cough
Symptomatic versus prophylactic antibiotic therapy for the reduction of urinary tract infections in patients with neurogenic bladder dysfunction using intermittent self-catheterisation
Systematic review of periodontal plastic surgery in the treatment of multiple recession-type defects
Systematic review of the effectiveness of botulinum toxin or radiotherapy for sialorrhea in patients with amyotrophic lateral sclerosis
Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease
Systemic antibiotics for chronic rhinosinusitis without nasal polyps in adults
Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults
Systemic antibiotics versus topical treatments for chronically discharging ears with underlying eardrum perforations
Systemic antimicrobial prophylaxis for percutaneous endoscopic gastrostomy
Systemic chemotherapy versus radiofrequency ablation plus systemic therapy for liver-predominant hepatic metastases of colorectal cancer
Systemic corticosteroids for acute gout
Systemic corticosteroids for acute sinusitis
Systemic corticosteroids for atopic eczema
Systemic drug treatment plus topical vitamin D derivatives for psoriasis
Systemic Family Therapy for children with depression
Systemic interventions for recurrent aphthous stomatitis (mouth ulcers)
Systemic therapy for treating locoregional recurrence in women with breast cancer
Systemic treatments for metastatic cutaneous melanoma
Tacrolimus for induction of remission in refractory ulcerative colitis
Tai Chi for chronic obstructive pulmonary disease (COPD)
Tai Chi for depression
Tai Chi for improving recovery after stroke
Tai Chi for Meniere's disease
Tai chi for osteoporosis
Tai chi for primary prevention of cardiovascular disease
Tai Chi for type 2 diabetes mellitus
Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults
Tamoxifen or letrozole versus standard methods for women with estrogen-receptor positive breast cancer undergoing oocyte or embryo cryopreservation in assisted reproduction
Tapentadol for chronic musculoskeletal pain in adults
Target of rapamycin inhibitors (TORi) as maintenance immunosuppression for kidney transplant recipients
Targeted broad band UVB for repigmentation in vitiligo
Targeted drug therapies for the management of metastatic colorectal cancer
Targeted therapy for advanced renal cell carcinoma
Taxane platinum combination chemotherapy versus single agent platinum for the first line treatment of epithelial ovarian cancer
Tea tree oil for acne
Teaching cognitive psychology/psychotherapy to people with schizophrenia
Technique modifications for reducing the risks from amniocentesis or chorionic villus sampling
Techniques and materials for skin closure in caesarean section
Techniques for the interruption of tubal patency for female sterilisation
Techniques of flushing and reperfusion for liver transplantation
Techniques of intrauterine fetal transfusion for women with red-cell isoimmunisation for improving health outcomes
Telehealthcare for chronic obstructive pulmonary disease
Telemedicine for chronic pain management in adults
Telemedicine for the support of parents of high-risk newborn infants
Telephone communication of HIV testing results for improving knowledge of HIV infection status
Telephone-based mental health interventions for children with attention deficit-hyperactivity disorder (ADHD)
Telerehabilitation services for stroke
Temozolomide for children and adolescents with diffuse intrinsic pontine glioma
Temozolomide for high grade glioma
Teratogenic risks of individual anti-epileptic drugs
Terbutaline pump maintenance therapy after threatened preterm labour for preventing preterm birth
Teriflunomide for multiple sclerosis
Teriflunomide for multiple sclerosis
Teriparatide (recombinant human parathyroid hormone 1-34) in postmenopausal women with osteoporosis
Terlipressin for hepatorenal syndrome
Testosterone for schizophrenia
Tests for diagnosis of common bile duct stones
Tetracycline versus doxycycline for Lyme disease
Thalidomide analogues for induction of remission in Crohn's disease
Thalidomide analogues for maintenance of remission in Crohn's disease
Thalidomide for managing cancer cachexia
The additional benefit of oral contraceptive pills containing cyproterone acetate for acne
The advantages of metformin in terms of cardiovascular outcomes
The best method for managing epilepsy in adults with intellectual disability
The best method for protein Z measurement
The biologically effective dose of stereotactic body radiotherapy for lung cancer
The biologically effective dose of stereotactic body radiotherapy for Stage I non-small-cell lung cancer
The clinical significance of resistance to P. acnes with topical antimicrobial use
The effect of adding inhaled corticosteroids to tiotropium and long-acting beta2-agonists for chronic obstructive pulmonary disease
The effect of different methods of remuneration on the behaviour of primary care dentists
The effect of financial incentives on the quality of health care provided by primary care physicians
The effect of high and low gestational weight gain stratified by prepregnancy BMI, on post-pregnancy weight retention
The effect of interventions to reduce Gestational Weight Gain on long term post partum weight retention
The effect of nutrition on the effect of antibiotic prophylaxis in acute necrotizing pancreatitis
The effect of oxytocin antagonists for inhibiting preterm labour on fetal outcome
The effect of preoperative treatment of P2Y12 receptor antagonists on perioperative bleeding and mortality in patients treated with coronary artery bypass grafting (CABG)
The effect of shift work on the control of diabetes
The effectiveness and safety of combined treatment with angiotensin antagonist and ace inhibitors for people with diabetes
The effects of anaesthetic agents on cortical mapping during neurosurgical procedures involving eloquent areas of the brain
The effects of antibiotic treatments on type 2 diabetes and metabolic disorder
The effects of long term pituitary down-regulation using GnRH agonists before in vitro fertilisation for women with endometriosis on the incidence of pregnancy complications
The efficacy of ablation versus excision versus laser versus diathermy surgery for subfertility associated with severe endometriosis
The impact of malocclusion/orthodontic treatment need on the quality of life
The impact of targeted drug therapies on current management of metastatic colorectal cancer
The impact of user fees on access to health services in low- and middle-income countries
The influence of tobacco smoking on the outcomes achieved by root-coverage procedures
The Lund concept for severe traumatic brain injury
The Marshall Protocol for Lyme disease
The McKenzie method for (sub)acute non-specific low-back pain
The McKenzie method for chronic non-specific low-back pain
The medical use of cannabis for reducing morbidity and mortality in patients with HIV/AIDS
The potential harms or costs of intensifying follow up for non-metastatic colorectal cancer patients
The Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) Trial with depression
The role of case registers in the long term management of people with schizophrenia in general practice
The role of concomitant extracorporeal photopheresis for the treatment of chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation
The role of continuing a sulphonylurea when starting premixed insulin
The role of fine needle aspiration biopsy (FNAB) and core needle biopsy (CNB) - alone or in combination - for diagnosing lung cancer in patients with a lung lesion
The role of high-frequency oscillations in epilepsy surgery planning
The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission
The role of non-pharmacological treatments in behavioural control as an alternative to rapid tranquillisation for schizophrenia
The role of positron emission tomography (PET) staging for small cell lung cancer (SCLC)
The role of self-monitoring of blood glucose (SMBG) as part of an integrated package, along with patient education and therapies, used to target type 2 diabetes
The role of short sleep duration on hypertension
The use of antiarrhythmics prior to cardioversion or catheter ablation for atrial fibrillation
The use of mecophenolate mofetil (MMF) in the treatment of IgA nephropathy
Theory-based interventions for contraception
Therapeutic and prophylactic drug interventions for Schistosomiasis japonicum
Therapeutic improvement of Eustachian tube function
Therapeutic touch for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Therapeutic ultrasound for carpal tunnel syndrome
Therapeutic ultrasound for carpal tunnel syndrome
Therapies for ocular metastases of melanoma
There is a lack of stability of asthma symptoms in children under two. What treatment would be best?
There is a need for accurate, continuous, non-invasive blood glucose monitoring in diabetes– how can we achieve this?
Thermal insulation for preventing inadvertent perioperative hypothermia
Thiazide diuretics and the risk of hip fracture
Thin split-thickness grafts for repigmentation in vitiligo
Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion
Thromboelastography (TEG) and thromboelastometry (ROTEM) for trauma-induced coagulopathy in adult trauma patients with bleeding
Thrombophilia testing for prevention of recurrent venous thromboembolism
Thrombopoietin mimetics for patients with myelodysplastic syndromes
Thromboprophylaxis for trauma patients
Thromboprophylaxis strategies for multiple myeloma patients undergoing immunomodulatory therapy with thalidomide or lenalidomide
Thymic peptides for treatment of cancer patients
Thymopentin for atopic eczema
Thyroid hormones for acute kidney injury
TI: Direct thrombin inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with non-valvular atrial fibrillation
Tiagabine for acute affective episodes in bipolar disorder
Tiagabine in the maintenance treatment of bipolar disorder
Tianma Gouteng Yin Formula for treating primary hypertension
Tidal versus other forms of peritoneal dialysis for acute kidney injury
Tight control of mild-moderate pre-existing or non-proteinuric gestational hypertension
Time course for blood pressure lowering of alpha blockers
Time course for blood pressure lowering of angiotensin-converting-enzyme inhibitors
Time course for blood pressure lowering of beta blockers with partial agonist activity
Time course for blood pressure lowering of beta one selective blockers
Time course for blood pressure lowering of dihydropyridine calcium channel blockers
Time course for blood pressure lowering of dual alpha and beta blockers
Timing of breast surgery in premenopausal breast cancer patients
Timing of dornase alfa inhalation for cystic fibrosis
Timing of hypertonic saline inhalation for cystic fibrosis
Timing of tracheostomy in trauma patients
Tinnitus retraining therapy
Tinzaparin for managing vaso-occlusive crises in people with sickle cell disease
Tiotropium plus formoterol vs tiotropium alone in patients with stable COPD
Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease
Tiotropium versus placebo for chronic obstructive pulmonary disease
TMC207 for treatment of people with pulmonary tuberculosis
To minimise selective pressure, would it be helpful to use benzoyl peroxide concomitantly whenever antibiotics are prescribed and, if so, would short washouts (say one week in four) suffice?
To what degree could a treatment harness the auditory brain's natural ability to reorganise itself to suppress the tinnitus sound?
To what extent are individuals with trimethylaminuria, and lack functional hepatic flavin containing monooxygenase 3 (FMO3) substrates, unable to oxidize other odiferous FMO3-specific substrates and does this contribute significantly to body odour?
Tobacco cessation services (including outreach services) that specifically focus on smokeless tobacco, compared to smokeless tobacco support provided by general tobacco cessation services
Tobacco smoking cessation for treating acne
Tocilizumab for rheumatoid arthritis
Tocolytics for preterm premature rupture of membranes
Tofacitinib for rheumatoid arthritis
Tong-xin-luo capsule for patients with coronary heart disease after percutaneous coronary intervention
Tonsillectomy for periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA)
Tonsillectomy versus non-surgical treatment for chronic/recurrent acute tonsillitis
Topical agents and dressings for fungating wounds
Topical agents or dressings for pain in venous leg ulcers
Topical anaesthesia for needle-related pain in newborn infants
Topical anaesthetic or vasoconstrictor preparations for flexible fibre-optic nasal pharyngoscopy and laryngoscopy
Topical analgesia for acute otitis media
Topical and systemic antifungal therapy for the symptomatic treatment of chronic rhinosinusitis
Topical antifungal treatments for tinea cruris and tinea corporis
Topical anti-oxidant and mitochondrial stimulating cream (VitilVenz) for repigmentation in vitiligo
Topical calcipotriol plus photochemotherapy (oral 8-MOP) for repigmentation in vitiligo
Topical calcipotriol plus UV light for repigmentation in vitiligo
Topical capsaicin (high concentration) for chronic neuropathic pain in adults
Topical cyclosporine A therapy for dry eye syndrome
Topical cyclosporine for atopic keratoconjunctivitis
Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease
Topical dapsone for acne
Topical glyceryl trinitrate for rotator cuff disease
Topical glycolic acid for acne
Topical human placental extract (melagenina) for repigmentation in vitiligo
Topical interventions for genital lichen sclerosus
Topical khellin combined with UVA compared to UVA alone for repigmentation in vitiligo
Topical lactic acid plus UVA for repigmentation in vitiligo
Topical microbicides for prevention of sexually transmitted infections
Topical nasal steroids for intermittent and persistent allergic rhinitis in children
Topical nasal steroids for treating nasal polyposis in people with cystic fibrosis
Topical non-steroidal anti-inflammatory agents for diabetic cystoid macular oedema
Topical NSAIDs for chronic musculoskeletal pain in adults
Topical phosphodiesterase inhibitors for atopic eczema
Topical pimecrolimus as monotherapy for repigmentation in vitiligo
Topical pimecrolimus compared to mild corticosteroids for atopic eczema
Topical pimecrolimus plus narrow band UVB for repigmentation in vitiligo
Topical plant–based catalase/dismutase for repigmentation in vitiligo
Topical preparations for preventing stretch marks in pregnancy
Topical pseudocatalase cream plus UVB for repigmentation in vitiligo
Topical psoralea tincture for repigmentation in vitiligo
Topical psoralens with sunlight (topical PUVAsol) for repigmentation in vitiligo
Topical retinoids compared to benzoyl peroxide for acne
Topical retinoids versus antimicrobial-based regimens for acne
Topical steroid for chronic rhinosinusitis without polyps
Topical steroids for nasal polyps
Topical steroids for repigmentation in vitiligo
Topical tacalcitol plus 308nm excimer laser for repigmentation in vitiligo
Topical tacalcitol plus narrow band UVB for repigmentation in vitiligo
Topical tacalcitol plus sunlight for repigmentation in vitiligo
Topical tacrolimus as monotherapy for repigmentation in vitiligo
Topical tacrolimus for atopic dermatitis
Topical tacrolimus plus 308nm excimer laser for repigmentation in vitiligo
Topical tacrolimus plus UV light for repigmentation in vitiligo
Topical treatment for facial burns
Topical treatments for chronic plaque psoriasis
Topical treatments for cutaneous warts
Topical treatments for HIV-related oral ulcers
Topical treatments for nail psoriasis
Topical treatments for vernal keratoconjunctivitis
Topiramate for essential tremor
Topiramate for the treatment of alcohol dependence
Topiramate for vestibular migraine
Topiramate monotherapy for juvenile myoclonic epilepsy
Topiramate prophylactic treatment for recurrent cluster headache
Toremifene versus tamoxifen for advanced breast cancer
Total disc replacement for chronic back pain in the presence of disc degeneration
Total fasciectomy for Dupuytren’s contractures of the hand
Total versus subtotal hysterectomy for benign gynaecological conditions
Total versus subtotal thyroidectomy for multinodular non-toxic goitre in adults
Totally implantable vascular access devices for cystic fibrosis
Totally percutaneous versus standard femoral artery access for elective bifurcated abdominal endovascular aneurysm repair
Toxicity reduction strategies in postoperative chemoradiotherapy for advanced squamous cell carcinoma of the head and neck
TPO receptor agonist for chronic idiopathic thrombocytopenic purpura
Tracheal intubation with a flexible intubation scope versus other intubation techniques for obese patients requiring general anaesthesia
Tracheal suctioning without disconnection in intubated ventilated neonates
Traction for low back pain with or without sciatica
Traditional Chinese herbal medicine for vascular dementia
Traditional Chinese medicinal herbs for condyloma acuminatum
Traditional Chinese medicine as a concomitant therapy for nasopharyngeal carcinoma
Traditional Chinese medicine for epilepsy
Traditional Chinese medicines for chronic hepatitis B
Trained medical interpreters in a face-to-face clinical setting for patients with low proficiency in the local language
Training health professionals in smoking cessation
Training interventions for improving telephone consultation skills in clinicians
Training to recognise the early signs of recurrence in schizophrenia
Training to recognise the early signs of recurrence in schizophrenia
Tranexamic acid for epistaxis
Tranexamic acid for reducing mortality in emergency and urgent surgery
Tranexamic acid for reducing mortality in emergency and urgent surgery
Tranexamic acid for upper gastrointestinal bleeding
Tranexamic acid to decrease blood loss and blood transfusion requirements for liver resection
Transarterial (chemo)embolisation for unresectable hepatocellular carcinoma
Transarterial (chemo)embolisation versus no intervention or placebo intervention for liver metastases
Transcatheter valve implantation versus aortic valve replacement for aortic stenosis in high-risk patients
Transcatheter versus optimal medical treatment and surgical aortic valve replacement for aortic valve stenosis
Transcendental meditation for the primary prevention of cardiovascular disease
Transcranial magnetic stimulation for schizophrenia
Transcranial magnetic stimulation for tinnitus
Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults
Transcutaneous electric nerve stimulation (TENS) in the treatment of pain in neurologic disorders
Transcutaneous electrical nerve stimulation (TENS) for chronic low-back pain
Transcutaneous electrical nerve stimulation (TENS) for low back pain
Transcutaneous electrical nerve stimulation for acute pain
Transdermal fentanyl for cancer pain
Transforaminal epidural steroid injections for low back pain
Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion
Transmyocardial laser revascularization versus medical therapy for refractory angina
Transobturator foramen procedures for stress incontinence
Transoral laser versus conventional surgery for the treatment of oral and oropharyngeal cancers
Transparent cap colonoscopy versus standard colonoscopy for investigation of gastrointestinal tract conditions
Transparent Cap Colonoscopy versus Standard Colonoscopy to Improve Caecal Intubation
Transperitoneal versus retroperitoneal approach for elective open abdominal aortic aneurysm repair
Transplacental versus direct fetal corticosteroid treatment for accelerating fetal lung maturation where there is a risk of preterm birth
Transpyloric versus gastric tube feeding for preterm infants
Transtheoretical model for dietary and physical exercise modification in weight loss management for overweight and obese adults
Transurethral radiofrequency collagen denaturation for the treatment of stress urinary incontinence in women
Transverse colostomy versus ileostomy for temporary decompression of colorectal and coloanal anastomosis
Transverse verses midline incisions for abdominal surgery
Trastuzumab containing regimens for early breast cancer
Treadmill interventions with partial body weight support in children under six years of age at risk of neuromotor delay
Treadmill training for patients with Parkinson's disease
Treating asymptomatic bacteriuria for incontinence
Treating BCG-induced disease in children
Treatment and follow-up of oral dysplasia
Treatment compliance in ulcerative colitis patients treated with MMX mesalamine
Treatment delivery using information and communication technology for people with schizophrenia
Treatment duration and optimal dose of terlipressin therapy in Type 1 hepatorenal syndrome (HRS)
Treatment duration for bevacizumab in metastatic colorectal cancer
Treatment for adverse effects of anti-epileptic medications
Treatment for avascular necrosis of bone in people with sickle cell disease
Treatment for cramps in amyotrophic lateral sclerosis/motor neuron disease
Treatment for cryoglobulinemic and non-cryoglobulinemic peripheral neuropathy associated with hepatitis C virus infection
Treatment for dysphagia (swallowing difficulties) in hereditary ataxia syndromes
Treatment for epilepsy in pregnancy: congenital malformation outcomes in the child
Treatment for epilepsy in pregnancy: neurodevelopmental outcomes in the child
Treatment for familial amyotrophic lateral sclerosis/motor neuron disease
Treatment for idiopathic and hereditary neuralgic amyotrophy (brachial neuritis)
Treatment for inhalant dependence and abuse
Treatment for Lambert-Eaton myasthenic syndrome
Treatment for lupus nephritis
Treatment for meralgia paraesthetica
Treatment for mitochondrial disorders
Treatment for osteoporosis in people with ?-thalassaemia
Treatment for paraneoplastic neuropathies
Treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome
Treatment for postpolio syndrome
Treatment for preventing bleeding in people with congenital bleeding disorders undergoing surgery
Treatment for sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis
Treatment for spasticity in amyotrophic lateral sclerosis/motor neuron disease
Treatment for subclinical hyperthyroidism in adults
Treatment for superficial thrombophlebitis of the leg
Treatment for ulnar neuropathy at the elbow
Treatment of acute bacterial rhinosinusitis
Treatment of antenatal depression using interventions other than pharmacological, psychological or psychosocial ones
Treatment of bruxism in children
Treatment of constipation on the number of urinary incontinence episodes in frail elderly people
Treatment of Lennox-Gastaut syndrome
Treatment of Lennox-Gastaut syndrome
Treatment of obstructive sleep apnoea for chronic cough in children
Treatment of recurrent stress urinary incontinence after failed minimally invasive synthetic suburethral tape surgery in women
Treatment of sleep-related epilepsy
Treatment of the clinically node-negative neck in primary parotid carcinoma
Treatment of urinary incontinence after stroke in adults
Treatment of valvular heart disease during pregnancy for improving maternal and neonatal outcome
Treatment with a single antibiotic versus a combination of antibiotics for Lyme disease
Treatments (i.e. Signs of Suicide, family interventions, therapeutic assessment, dialectical behaviour therapy, cognitive behavioural therapy, pharmacological therapy) in adolescents with self-harm for prevention of recurrence
Treatments for adults with prominent lower front teeth
Treatments for basal cell carcinoma
Treatments for breast abscesses in breastfeeding women
Treatments for breast engorgement during lactation
Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews
Treatments for constipation in children and young adults undergoing cancer treatment
Treatments for depression/anxiety for patients with heart failure
Treatments for gestational diabetes
Treatments for gestational diabetes and impaired glucose tolerance in pregnancy
Treatments for peri-menstrual seizures
Treatments for suppression of lactation
Treatments other than antibiotics for acute sore throat
Trial of instrumental delivery in theatre versus immediate caesarean section for anticipated difficult assisted births
Trials are needed that address the difference between technical blood glucose control in the laboratory and real life experience of blood glucose strips for people with diabetes
Triamcinolone for chronic asthma
Tricyclic antidepressants for autism spectrum disorders (ASD) in children and adolescents
Tricyclic drugs for depression in children and adolescents
Trifluoperazine versus placebo for schizophrenia
Trimetazidine for adult chronic heart failure patients
Trimetazidine for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
True level of efficacy of ciclosporin for psoriasis
Tryptophan and 5-Hydroxytryptophan for depression
Tumor necrosis factor-alpha antibody for early Crohn's disease
Tumor necrosis factor-alpha antibody for maintenance of remission of Crohn's disease in paediatric patients
Tumor necrosis factor-alpha antibody for maintenance of remission of Crohn's disease in pregnant patients
Types of anti-oxidant multivitamin supplements used to slow or prevent progression of age-related macular degeneration important
Types of indwelling urinary catheters for long-term bladder drainage in adults
Tyrosine supplementation for phenylketonuria
Ulinastatin and thymosin as immune modulators for the treatment of sepsis
Ulinastatin versus placebo for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Ultra-radical (extensive) surgery versus standard surgery for the primary cytoreduction of advanced epithelial ovarian cancer
Ultrasonography for diagnosis of acute appendicitis
Ultrasonography for endoleak detection after endoluminal abdominal aortic aneurysm repair
Ultrasonography or PET-CT in the staging and surveillance of melanoma patients
Ultrasound and shockwave therapy for acute fractures in adults
Ultrasound for determining a viable intrauterine pregnancy
Ultrasound scans for people with cirrhosis
Ultrasound use for the placement of haemodialysis catheters
Ultraviolet treatment compared to oral immunomodulatory treatment for severe atopic eczema
Umbilical vein injection for the routine management of third stage of labour
Unfractionated heparin compared with compression therapy for deep vein thrombosis (DVT) prophylaxis.
Unfractionated heparin versus low molecular weight heparin for avoiding heparin-induced thrombocytopenia in postoperative patients
Universal family-based prevention programs for alcohol misuse in young people
Universal multi-component prevention programs for alcohol misuse in young people
Universal school-based prevention programs for alcohol misuse in young people
Urethral injection therapy for urinary incontinence in women
Uricosuric medications for chronic gout
Urinary catheter policies for long-term bladder drainage
Urinary diversion and bladder reconstruction/replacement using intestinal segments for intractable incontinence or following cystectomy
Urodynamic studies for management of urinary incontinence in children and adults
Ursodeoxycholic acid for cystic fibrosis-related liver disease
Ursodeoxycholic acid for cystic fibrosis-related liver disease
Ursodeoxycholic acid for primary biliary cirrhosis
Use of a closed loop system to control diabetes
Use of cervical assessment by ultrasound in pregnant women to prevent preterm birth
Use of EEG as standard practice in the monitoring of effective treatment in neonatal seizures
Use of electronic health records to support smoking cessation
Use of hyaluronidase as an adjunct to local anaesthetic eye blocks
Use of plastic adhesive drapes during surgery for preventing surgical site infection
Use of statins in dialysis patients
Use of statins in kidney transplant patients
Use of statins in patients with chronic kidney disease
Using alternative statistical formats for presenting risks and risk reductions
Uterine artery embolization for symptomatic uterine fibroids
Uterine muscle relaxant drugs for threatened miscarriage
Utero-placental Doppler ultrasound for improving pregnancy outcome
Utility, acceptability and safety of available drugs for urgent sedation (including atypical antipsychotics) for psychosis
UVA monotherapy for repigmentation in vitiligo
UVB phototherapy plus emollients compared to UVB alone for psoriasis
Vaccination for preventing postherpetic neuralgia
Vaccines for measles, mumps and rubella in children
Vaccines for preventing herpes zoster in older adults
Vaccines for preventing influenza in healthy children
Vaccines for preventing influenza in people with asthma
Vaccines for preventing influenza in people with cystic fibrosis
Vaccines for preventing rotavirus diarrhoea: vaccines in use
Vaccines for prophylaxis of viral infections in patients with hematological malignancies
Vaccines to prevent acute otitis media in children
Vaginal dilator therapy for women receiving pelvic radiotherapy
Vaginal progesterone for women with an asymptomatic short cervix to prevent neonatal mortality or morbidity in twin pregnancy
Valproic acid and sodium valproate for neuropathic pain and fibromyalgia in adults
Vascular-endothelial-growth-factor (VEGF) targeting therapies for endocrine refractory or resistant metastatic breast cancer
Vasectomy occlusion techniques for male sterilization
Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss
Vasodilators and vasoactive substances for idiopathic sudden sensorineural hearing loss
Vasodilators for women undergoing assisted reproduction
Vasopressin and its analogues for the treatment of refractory hypotension in neonates
Venlafaxine for depression
Venom immunotherapy for preventing allergic reactions to insect stings
Veno-venous bypass versus none for liver transplantation
Vestibular rehabilitation exercises for chronic dizziness
Vestibular rehabilitation for unilateral peripheral vestibular dysfunction
Vibroacoustic stimulation for fetal assessment in labour in the presence of a nonreassuring fetal heart rate trace
Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates
Vigabatrin for refractory partial epilepsy
Vigabatrin versus carbamazepine monotherapy for epilepsy
Virtual reality for stroke rehabilitation
Virtual reality simulation training for health professions trainees in gastrointestinal endoscopy
Virtual reality training for improving the skills needed for performing surgery of the ear, nose or throat
Vitamin A for the prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection
Vitamin A supplementation for cystic fibrosis
Vitamin A supplementation for preventing morbidity and mortality in children from 6 months to 5 years of age
Vitamin and anitioxidant supplementation for people with deficiencies for prevention of cardiovascular disease
Vitamin B for schizophrenia
Vitamin B1 for primary and secondary dysmenorrhoea
Vitamin C and selenium for rheumatoid arthritis
Vitamin C for asthma and exercise induced bronchoconstriction
Vitamin C for preventing and treating the common cold
Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Vitamin D for multiple sclerosis
Vitamin D for the management of multiple sclerosis
Vitamin D supplementation for cystic fibrosis
Vitamin D supplementation for prevention of mortality in adults
Vitamin D supplementation for women during pregnancy
Vitamin E for age-related macular degeneration to slow distance visual acuity change or progression
Vitamin E for Alzheimer's dementia and mild cognitive impairment
Vitamin E for neuroleptic-induced tardive dyskinesia
Vitamin K antagonists or low-molecular-weight heparin for the long term treatment of symptomatic venous thromboembolism
Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin
Vitamin K for improved anticoagulation control in patients receiving warfarin
Vitamin K for upper gastrointestinal bleeding in patients with acute or chronic liver diseases
Vitamin K for upper gastrointestinal bleeding in patients with liver diseases
Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage
Vitamin K supplementation for cystic fibrosis
Vitamin supplements (including B12, vitamin C and folic acid) for repigmentation in vitiligo
Vitrification versus slow freezing for women undergoing oocyte cryopreservation
Vocational rehabilitation for enhancing return-to-work in workers with traumatic upper limb injuries
\Hou WH, Chi CC, Lo HL, Kuo KN, Chuang HY. Vocational rehabilitation for enhancing return-to-work in workers with traumatic upper limb injuries (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 8. Art. No.: CD010002. DOI: 10.1002/14651858.CD010002
Vocational rehabilitation for persons with multiple sclerosis
Voluntary counseling and testing (VCT) for changing HIV-related risk behavior in developing countries
Warfarin therapy for non-atrial fibrillation heart failure
Warm water infusion versus air insufflation for aiding colonoscopy insertion
Warming of intravenous and irrigation fluids for preventing inadvertent perioperative hypothermia
Water for preventing urinary stones
Water for wound cleansing
Water precautions for prevention of infection following tympanostomy tube (grommet) insertion in children
Water softeners for atopic eczema
Water-based exercise for asthma in adults
Water-based exercise programmes for the treatment of mild multiple sclerosis
Weight loss for non-alcoholic fatty liver disease
Weight loss intervention through lifestyle modification or pharmacotherapy for obstructive sleep apnoea in adults
Weight loss interventions for chronic asthma
Welfare to work interventions and their effects on health and well-being of lone parents and their children
What actions should I take to help my asthma symptoms associated with my menstrual cycle?
What alternatives are there for treating asthma other than medication?
What are my future treatment options for my schizophrenia when the medicine has not helped?
What are patient beliefs regarding concordance with prescribed treatments and complementary therapies in adults with psoriasis and psoriatic arthritis?
What are relative advantages and disadvantages of different isomers of salbutamol?
What are the advantages and disadvantages of a flutter device for asthma medication in combination with carbocisteine 375 x 3 day to stop or reduce mucus formation?
What are the advantages and disadvantages of breath-actuated inhalers compared with traditional inhalers?
What are the advantages and disadvantages of complementary treatments for asthma?
What are the advantages and disadvantages of nebulisers vs spacers for asthma?
What are the advantages and disadvantages of the new smaller salbutamol inhaler compared with the older larger salbutamol inhalers?
What are the advantages referral to a specialist for asthma?
What are the adverse effects associated with the long term-use of long-acting bronchodilators?
What are the adverse effects associated with the long term-use of short-acting bronchodilators for adults and children?
What are the adverse effects associated with the long-term use of combination and additive therapies for asthma?
What are the adverse effects associated with the long-term use of inhaled steroid therapies?
What are the adverse effects associated with the long-term use of oral steroid therapies?
What are the adverse effects associated with the long-term use of steroid drug therapies for asthma in children?
What are the benefits and harms of immunosuppressive regimens containing TOR-I when compared to other regimens as initial therapy for kidney transplant recipients?
What are the benefits and harms of phosphate binders in chronic kidney disease (CKD)?
What are the benefits and optimum structure of rehabilitation programmes in adults with testicular germ cell tumours?
What are the benefits of adjuvant drugs in pemphigus?
What are the benefits of breathing exercise as a form of physical therapy for asthma?
What are the benefits of continuing to use medication, over experiencing side-effects for children with mild asthma?
What are the benefits of different surgical procedures for epilepsy?
What are the benefits of disposable insulin pens vs. non disposable insulin pens?
What are the benefits/harm of running higher glycaemic control to reduce long term adverse events?
What are the best after-care measures for men who have had radical treatment for prostate cancer?
What are the best analgesics to decrease oral pain in patients with dystrophic epidermolysis bullosa?
What are the best and safest natural products to apply to the skin for eczema?
What are the best forms of insulin for treating type 1 diabetes?
What are the best injection sites for delivering insulin for diabetes?
What are the best interventions to improve balance/minimise symptoms in daily activities such as supermarkets, escalators etc.?
What are the best materials for prosthesis in dystrophic epidermolysis bullosa patients?
What are the best methods of remembering to take epilepsy medication?
What are the best patient reported outcomes to monitor treatment for pernicious anaemia?
What are the best treatments for men with prostate cancer over the age of 70?
What are the best ways to improve cognition after stroke?
What are the characteristics of the best type 1 diabetes patient education programmes (from diagnosis to long term care) and do they improve outcomes?
What are the cognitive and psychological effects of living with type 1 diabetes?
What are the costs of chronic heart disease screening for patients with psoriasis?
What are the educational, employment and personal (eg relationships) outcomes for individuals with cleft lip/palate during childhood, adolescence and in the long term?
What are the effective treatments for the side effects of hormone therapy taken for prostate cancer?
What are the effects of two compounds of betamethasone dipropionate 0.05% plus calcipotriol ointment with clobetasol propionate 0.05% ointment on psoriasis and psoriatic arthritis?
What are the effects of adrenoceptor agonists for women with stress incontinence?
What are the effects of alternate day (once daily) calcipotriol 50 mcg/g ointment and either clobetasol propionate 0.05% ointment or betamethasone dipropionate 0.05% ointment with once daily two compound (calcipotriol 50 mcg/g combined with betamethasone dipropionate 0.05%) ointment on adults with psoriasis and psoriatic arthritis?
What are the effects of annual review of asthmatic patients by telephone?
What are the effects of antiepileptic drugs on gums?
What are the effects of antiepileptic drugs on teeth?
What are the effects of antiepileptic drugs on the liver?
What are the effects of antipsychotic drugs and/or psychological interventions in early onset schizophrenia?
What are the effects of antipsychotic drugs on children with early symptoms of schizophrenia?
What are the effects of breathing exercises in asthma?
What are the effects of Bricanyl infusion compared to alternatives for asthma?
What are the effects of complementary therapies for schizophrenia?
What are the effects of epilepsy medications on female fertility?
What are the effects of individual anti-epileptic drugs on a developing child?
What are the effects of routine screening for proteinuria (testing urine for protein) in healthy pregnant women?
What are the effects of short contact dithranol and coal tar solution on psoriasis and psoriatic arthritis?
What are the effects of stress on glucose levels in people with type 1 diabetes?
What are the effects on the incidence of pre-eclampsia of progesterone given to prevent preterm birth?
What are the exact mechanisms involved in anti-epileptic drug (AED) induced teratogenesis?
What are the factors that predict the psychological outcomes for individuals with cleft lip/palate?
What are the family characteristics that promote success in the treatment of child and adolescent obesity?
What are the gender differences in side effects from anti-epileptic drugs?
What are the hormonal differences in side effects from anti-epileptic drugs?
What are the impacts of different anti-epileptic drugs on children after birth?
What are the indications for discontinuing medication in patients with schizophrenia?
What are the information needs of patients with psoriasis and psoriatic arthritis in terms of timing (at initial diagnosis, when changing from one treatment to another), method (one-to-one session, written information booklet, online), and setting (GP consultation, practice nurse consultation dermatology/rheumatology consultation, nurse specialist consultation, occupational health consultation)
What are the information needs of psoriatic arthritis patients in terms of information and education, Quality of Life issues, psychosocial support, involvement in care and patient satisfaction?
What are the key components of successful ‘Self-management’ for a person with asthma?
What are the long term adverse effects of inhalers used to treat asthma?
What are the long term adverse effects of medication for asthma?
What are the long term adverse effects of methotrexate tablets when taken for psoriatic arthritis?
What are the long term adverse effects of steroids for asthma?
What are the long term adverse effects of steroids for asthma?
What are the long term adverse effects of steroids for asthma?
What are the long term adverse effects on adults who are on potent to very potent topical corticosteroids for psoriasis and psoriatic arthritis?
What are the long term adverse metabolic effects of antipsychotic medication?
What are the long term effect of prescribed drugs for asthma?
What are the long term effects of combined steroid and beta-2 agonist inhalers on the voice?
What are the long term effects of Deep Brain Stimulation (DBS) in patient with a mental health problem?
What are the long term effects of inhaled steroids for asthma?
What are the long term effects of inhaled steroids for asthma?
What are the long term effects of inhaling steroids for asthma?
What are the long term effects of medication for asthma in children?
What are the long term effects of medication for asthma?
What are the long term effects of medication for asthma?
What are the long term effects of medication for asthma?
What are the long term effects of over medication for asthma?
What are the long term effects of repeated short courses of steroid tablets in children with asthma?
What are the long term effects of salbutamol inhalers for asthma in children?
What are the long term effects of steroids for asthma in children?
What are the long term effects of steroids for asthma?
What are the long term effects of steroids for asthma?
What are the long term effects of steroids I take for asthma?
What are the long term effects of steroids used to treat asthma?
What are the long term effects of taking Beta2-adrenergic receptor agonists for asthma?
What are the long term effects of taking medication for asthma?
What are the long term effects of taking medication for asthma?
What are the long term effects of taking steroids for asthma?
What are the long term effects of taking steroids for asthma?
What are the long term effects of taking steroids for asthma?
What are the long term effects of taking steroids for asthma?
What are the long term effects of the leukotriene receptor antagonists I take for asthma?
What are the long term effects of the steroids I take for asthma?
What are the long term effects of the steroids I take for asthma?
What are the long term effects of treating seizures in babies versus not treating?
What are the long term effects of using high doses of steroids used to treat asthma?
What are the long term effects of using inhalers for asthma?
What are the long term effects of using inhalers to treat asthma?
What are the long term effects of using medication to treat asthma and are they reversible?
What are the long term effects of using medication to treat asthma?
What are the long term effects of using preventor inhalers to treat asthma?
What are the long term effects of using steroids for asthma?
What are the long term effects of using steroids for asthma?
What are the long term effects of using steroids to treat asthma?
What are the long term effects on a young child of taking steroids for asthma?
What are the long term harmful effects of steroid inhalers started during childhood?
What are the long term harmful effects of steroid inhalers started during childhood?
What are the long term results of syndactilia surgery for patients with dystrophic epidermolysis bullosa?
What are the long term side affects of tranquillizers taken with antypsychotics in the treatment of schizophrenia?
What are the long term side effects of asthma medications?
What are the long term side effects of chronic use of antacid drugs in dystrophic epidermolysis bullosa?
What are the long term side effects of frequent pressure dressings in patients with dystrophic epidermolysis bullosa?
What are the long term side effects of frequent topical antibacterial drugs use in patients with dystrophic epidermolysis bullosa?
What are the long term side effects of frequent topical corticosteroid use in patients with dystrophic epidermolysis bullosa?
What are the long term side effects of steroids for asthma?
What are the long term side effects on growth (height + feet) of treating asthma in children with steroid inhalers?
What are the long-term adverse effects of continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus?
What are the long-term complication rates associated with the various forms of insulin used to treat diabetes?
What are the long-term effects of aldosterone antagonists for preventing the progression of chronic kidney disease?
What are the long-term effects of inhalers (e.g. Becotide/Ventolin) used on babies and toddlers?
What are the long-term effects of taking isotretinoin for acne? In particular, if it raises cholesterol so significantly during the course of treatment, is there any evidence to show future problems linked to this?
What are the long-term risks and effects on quality of life of different bladder management strategies for lower urinary tract dysfunction in people with neurological disease?
What are the long-term risks associated with epilepsy surgery?
What are the minimum requirements of successful Patient Education / Self-Management programme for the care of people with asthma, (In terms of resources / practical issues)? Are they the same for all groups?
What are the most clinically effective and cost-effective methods of addressing patient and carer concerns about strong opioids, including anticipating and managing adverse effects, and engaging patients in prescribing decisions?
What are the most cost- and resource-effective methods of treating child and adolescent obesity in different health care settings?
What are the most effective and safe emollients in treating eczema?
What are the most effective catheter type, placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients?
What are the most effective treatment protocols for women with stress, urge or mixed urinary incontinence and an inability to voluntarily contract pelvic floor muscles?
What are the most effective treatments of daytime urinary incontinence in children?
What are the most effective types of continence services for people with urinary incontinence
What are the optimal laboratory methods for assessment of degree of anticoagulation in emergency preoperative settings using apixaban?
What are the optimal laboratory methods for assessment of degree of anticoagulation in emergency preoperative settings using dabigatran etexilate?
What are the optimal laboratory methods for assessment of degree of anticoagulation in emergency preoperative settings using rivaroxaban?
What are the optimal methods for reversal of anticoagulation in patients receiving apixaban who experience bleeding?
What are the optimal methods for reversal of anticoagulation in patients receiving dabigatran etexilate who experience bleeding?
What are the optimal methods for reversal of anticoagulation in patients receiving rivaroxaban who experience bleeding?
What are the optimal pelvic floor muscle training protocols (frequency and duration of therapy) for the treatment of different patterns of urinary incontinence?
What are the outcomes for people with psoriasis following long term corticosteroid use
What are the potential harms as well as benefits of different interventions for weight reduction?
What are the potential long term effects of using steroids for asthma?
What are the psychosexual and gonadal functions in men following treatment for testicular germ cell tumours?
What are the psycho-social implications for young children with diabetes, of needing others to administer injections during the school day?
What are the relative advantages and disadvantages of Seretide 50 and Seretide 250? Will the higher dose cause problems for my very sensitive skin?
What are the relative merits and demerits of the combination inhalers Symbicort and Seretide in managing chronic asthma in adults?
What are the risks and benefits associated with analgesia and anaesthesia in women with diabetes?
What are the risks associated with the potential interaction between Vitamin K antagonists and low-dose paracetamol (<2 g/day).
What are the risks of different surgical procedures for epilepsy?
What are the safety and efficacy of surgical treatments for posterior canal BPPV?
What are the side effects of protective dressings in patients with dystrophic epidermolysis bullosa?
What are the side effects of steroids taken for treatment of asthma?
What are the side effects on the bowel of radiotherapy for prostate cancer?
What are the treatment options other than using drugs that suppress the immune system for people with eczema?
What can be done to delay or prevent the onset of hormone independent prostate cancer?
What can be done to delay or prevent the onset of hormone independent prostate cancer?
What can be done to improve the experience of families of a baby with cleft lip/palate at time of birth in hospital?
What can be done to prevent cleft lip/palate?
What can I avoid to prevent the growth of a tumour in the prostate?
What can we do to improve treatment of people with epilepsy in A&E departments?
What catheter regimens are most effective in preventing urinary tract infections in patients using intermittent self-catheterisation for the management of a neurogenic bladder?
What clinical and patient characteristics determine the effectiveness and acceptability of conservative and surgical strategies for the management of neurogenic bladder following spinal cord injury?
What clinical and patient characteristics determine the effectiveness and acceptability of treatment and management strategies for neurogenic bladder dysfunction in multiple sclerosis?
What clinical and patient characteristics determine the effectiveness and acceptability of treatment and management strategies for neurogenic bladder dysfunction in spina bifida?
What cost-effective interventions can be used to increase hepatitis B case-finding among migrant populations in primary and secondary care?
What effect do steroid inhalers have on the body given that I take oral steroids two or three times a year for short periods?
What effect does exercise have on blood pressure and the incidence of pre-eclampsia?
What effective management strategies are there for tinnitus-related insomnia?
What effective models of home phototherapy are there for adults with psoriasis and psoriatic arthritis?
What effective treatments are there for pulsatile tinnitus?
What effects do anti-epileptic drugs have during pregnancy on the child?
What effects do anti-epileptic drugs have during pregnancy on the child?
What evidence is there that a prostate cancer awareness programme would improve outcomes?
What evidence is there that complementary therapies can reduce asthma severity?
What evidence is there to support the present recommendations of a high carbohydrate diet for the treatment of Type 1 and Type 2 diabetes?
What exposures pre- and during pregnancy increase the risk of having a baby with a cleft?
What family caregiver characteristics improve the effect of behavioral interventions for urinary incontinence?
What impact do changing hormones, for example during menstruation, pregnancy and menopause, have on blood glucose levels in women with type 1 diabetes?
What impact does psoriatic arthritis have on activities of daily living?
What interventions are effective in preventing Ménière's disease going to the second ear?
What interventions are most effective at different levels of obesity severity and at different ages and developmental stages?
What interventions are most effective for specific ethnicities, religious groups or culturally diverse populations for weight reduction
What interventions would enhance the educational outcomes for children with cleft lip/palate?
What is best practice for the treatment of combined stress urinary incontinence and detrusor overactivity?
What is the added prognostic value of measuring bone mineral density in the assessment of fracture risk with FRAX?
What is the appropriate timing for undertaking radiotherapy in relation to prostate surgery?
What is the benefit of incretin therapy for the treatment of type 1 diabetes?
What is the benefit of temperature measurements in patients with or at risk of diabetic foot, who have not yet lost the sensation to SWM (Semmes-Weinstein monofilament) sensation?
What is the benefit of Transcranical Magnetic Stimulation (TMS) for schizophrenia?
What is the best and safe test way to use oral antibiotic treatments?
What is the best and safest treatment for eczema in sensitive areas such as the eyes and the genital area?
What is the best and safest treatment taken by mouth for eczema?
What is the best and safest way of using calcineurin inhibitors applied to the skin for people with eczema?
What is the best and safest way of using drugs that suppress the immune system when treating eczema?
What is the best and safest way of using topical steroids for eczema?
What is the best and safest way of using wet wraps for people with eczema?
What is the best and safest way to use antimicrobials (antibiotics, antifungals and antiseptics) applied to the skin for people with eczema?
What is the best and safest way to use treatments applied to my skin (not including steroids and calcineurin inhibitors)?
What is the best and safest way to use ultraviolet light to treat eczema?
What is the best approach to treating the psychological impact of sexual dysfunction arising from prostate cancer treatment?
What is the best choice of steroid, dose and number of injections for local injection in the treatment of carpal tunnel syndrome?
What is the best contraceptive for women with dystrophic epidermolysis bullosa?
What is the best feeding method for babies with cleft lip/palate, including those with syndromes (including breast feeding, nasogastric tubes and weaning times?)
What is the best format to deliver patient information for improving management, self care and adherence with treatment in patients with atopic eczema.
What is the best intervention for early stage, moderate risk prostate cancer?
What is the best method of maintaining good/adequate oral hygiene in patients with dystrophic epidermolysis bullosa?
What is the best pain control strategy to decrease pain during wound care and bathing in patients with dystrophic epidermolysis bullosa?
What is the best post-surgical care for people with epilepsy?
What is the best protocol for primary repair of the lip and palate, including technique/timing and sequence?
What is the best psychological treatment for itching/scratching in eczema ?
What is the best psychological treatment for the relief of stress in the treatment of eczema?
What is the best psycho-social intervention for partners of men with prostate cancer?"
What is the best therapy for renoprotection - ACEi or ARBs - and what is the role of combination therapy?
What is the best treatment for adult testicular germ cell tumours?
What is the best treatment for advanced prostate cancer?
What is the best treatment for men with high risk localised prostate cancer?
What is the best treatment for otitis media with effusion (OME - glue ear) in individuals with cleft lip/palate?
What is the best treatment for prostate cancer recurrence?
What is the best treatment for the residual hearing loss and tinnitus in end-stage (no vertigo attacks) Ménière's disease?
What is the best treatment to control itch in patients with dystrophic epidermolysis bullosa?
What is the best treatment to produce rapid recovery of balance following a Ménière's attack?
What is the best way of cleaning the aerochamber device used with ventolin inhalers?
What is the best way of dealing with allergies to cats & dogs to prevent asthma?
What is the best way of managing the adverse effects from radiotherapy given for prostate cancer?
What is the best way of responding, in the short term, to severe challenging behaviour and agitation in relation to the use of anti-psychotics in schizophrenia?
What is the best way of training health professionals in the management of balance disorders?
What is the best way or method to administer thromboprophylaxis during pregnancy and the puerperium?
What is the best way stop prostate cancer spreading?
What is the best way to counter an asthma attack if you do not have your medication available?
What is the best way to manage end of life care for men with advanced prostate cancer'
What is the best way to manage infants with Cleft lip and or palate undergoing primary surgery before, during and after in hospital?
What is the best way to manage pain in advanced prostate cancer?
What is the best way to monitor tissue cell function when a patient is taking any of the forms of B12 for classic pernicious anaemia?
What is the best way to prevent tooth decay in children with cleft lip/palate?
What is the best way to promote adherence with emollient and topical corticosteroid therapies for adults with atopic eczema?
What is the best way to teach professionals about caring for people with asthma?
What is the best way to treat febrile seizures?
What is the best way to treat hormone independent prostate cancer'?
What is the best way to treat low risk prostate cancer?
What is the best way to treat people with schizophrenia un-responsive to treatment?
What is the best way to treat the social impacts of a diagnosis of prostate cancer and its treatment?
What is the best way, for people with type 1 diabetes, to manage thier weight?
What is the cardiovascular risk, and safety of non-steroidal anti-inflammatory drugs in adults with psoriasis and psoriatic arthritis?
What is the clinical and cost effectiveness of a 'bypass surgery first' strategy compared with an 'angioplasty first' strategy for treating people with critical limb ischaemia caused by disease of the infra-geniculate (below the knee) arteries?
What is the clinical and cost effectiveness of a whole-leg ultrasound scan compared with a proximal leg vein ultrasound scan in the diagnosis of acute deep vein thrombosis (DVT)?
What is the clinical and cost effectiveness of chlorhexidine in various strengths and formulations for cleansing skin and preventing infections for patients with vascular access devices?
What is the clinical and cost effectiveness of clot removal using catheter-directed thrombolytic therapy or pharmacomechanical thrombolysis compared with standard anticoagulation therapy for the treatment of acute proximal DVT?
What is the clinical and cost effectiveness of different monitoring intervals for detection of disease progression in Chronic Open Angle Glaucoma patients at risk of progression?
What is the clinical and cost effectiveness of intrapartum antibiotic prophylaxis using benzylpenicillin in women with preterm labour?
What is the clinical and cost effectiveness of laboratory investigations used individually or in combination to exclude early-onset neonatal infection in babies receiving antibiotics for suspected infection?
What is the clinical and cost effectiveness of providing glaucoma patients with a ‘glaucoma card’ or individual record of care compared to standard treatment?
What is the clinical and cost effectiveness of systemic pharmacological thrombolysis compared with standard initial anticoagulation therapy in patients with confirmed PE and haemodynamic stability who present with right ventricular dysfunction?
What is the comparative effectiveness of conservative treatments for bladder control problems following prostate surgery?
What is the comparative efficacy and safety of leflunomide, sulfasalazine and methotrexate for psoriatic arthritis, in doses regularly used in current practice?
What is the correct needle length for injecting insulin for diabetes?
What is the cost and benefit of new imaging modalities for rheumatoid arthritis?
What is the current evidence concerning anti-epileptic drugs effect on bones?
What is the determination of the phototherapy action spectrum in adults with psoriasis and psoriatic arthritis?
What is the direct effect on health-related quality of life associated with weight loss, or of avoiding weight gain, for people with type 2 diabetes?
What is the duration of the course of antibiotics used to treat acute pyelonephritis in children?
What is the effect of adding a progestagen to oestrogen therapy in post-menopausal women with an intact uterus who have urinary incontinence?
What is the effect of anti tumour necrosis factor therapy on the ability of people with rheumatoid arthritis to remain in employment?
What is the effect of antipsychotic medication on people with learning disability?
What is the effect of early intervention in psoriasis and psoriatic arthritis with disease-modifying anti-rheumatic drugs on incidence of comorbidity, joint damage and disability, compared to late intervention?
What is the effect of exercise, stress or lifestyle on the anticoagulant action of warfarin?
What is the effect of land-based physical exercise on pain and physical function in osteoarthritis of the hip?
What is the effect of people's attitudes and beliefs about their peripheral arterial disease on the management and outcome of their condition?
What is the effect of resistance training for knee osteoarthritis on arthritis symptoms, physical performance and psychological function?
What is the effect of sea baths or swimming pools in the evolution of lesions in patients with dystrophic epidermolysis bullosa?
What is the effectiveness and cost-effectiveness of initial argon, diode or selective laser trabeculoplasty treatment compared to PGA alone or laser + PGA in combination in COAG patients?
What is the effectiveness and safety of prophylactic antibiotic therapy for the prevention of urinary tract infections in patients using intermittent self-catheterisation for the management of a neurogenic bladder?
What is the effectiveness of anti-embolism stockings in non-stroke medical patients?
What is the effectiveness of different routes of oestrogen therapy administration in post-menopausal women with urinary incontinence?
What is the effectiveness of duration of oestrogen therapy treatment in post-menopausal women with urinary incontinence?
What is the effectiveness of full and knee length anti-embolism stockings in non-stroke patients?
What is the effectiveness of gene therapy for prostate cancer?
What is the effectiveness of intermittent hormone therapy (known as intermittent androgen suppression (IAS) or intermittent androgen deprivation (IAD)) for prostate cancer?
What is the effectiveness of interventions to maintain the benefits of treatment and prevent relapse after successful treatment for conduct disorder?
What is the effectiveness of maximal androgen blockade (i.e. an anti-androgen tablet and LHRH analogues) in treatment for prostate cancer?
What is the effectiveness of new treatments for prostate cancer such as High Intensity Focused Ultrasound (HIFU) and Cryotherapy?
What is the effectiveness of new treatments for prostate cancer such as High Intensity Focused Ultrasound and Cryotherapy?
What is the effectiveness of parent training programmes for conduct disorders in children and young people aged 12 years and over?
What is the effectiveness of radiotherapy as a secondary treatment in prostate cancer?
What is the efficacy of classroom-based interventions for conduct disorders?
What is the efficacy of combining treatment for mental health problems in parents with treatment for conduct disorders in their children?
What is the efficacy of patient self-administered Semont manoeuvre or canalith repositioning procedure for benign paroxysmal positional vertigo?
What is the evidence for gargling aspirin as an analgesic for sore throat?
What is the evidence for heliox in the immediate treatment of acute asthma?
What is the evidence for increasing the dose of inhaled steroids in a mild asthma exacerbation?
What is the evidence for leukotriene receptor antagonists in the immediate treatment of acute asthma?
What is the evidence for magnesium sulphate in the immediate treatment of acute asthma?
What is the evidence for using natural progesterone in treatment of hair loss on perimenopausal woman? Also which hormone replacement treatment might help?
What is the evidence for using SSRI's (antidepressant medication) for the treatment of menopausal flushing?
What is the evidence that dietary changes reduce the likelihood of recurrence of prostate cancer after radical treatment?
What is the evidence that taking supplements reduces the likelihood of recurrence after radical treatment for prostate cancer?
What is the experience for patients of drug treatments, both conventional and atypical antipsychotics, for schizophrenia?
What is the impact of family interventions on the symptoms of schizophrenia?
What is the impact of having a baby born with cleft lip/palate on maternal/child attachment?
What is the impact of parenting approach on the outcomes for children with cleft lip/palate?
What is the impact of working or stress for a pregnant women who has increased blood pressure that has not reached the threshold for being called 'hypertension'?
What is the importance of maintaining the PH level of the skin for people with eczema?
What is the link between tinnitus and balance problems (including Meniere's disease, benign paroxysmal positional vertigo )
What is the link between tinnitus and hyperacusis (over-sensitivity to sounds)?
What is the link between tinnitus and mood disorders?
What is the live birth rate in women taking Pentoxifylline
What is the long term effect of steroid use for asthma on bones?
What is the long term safety of applying steroids to the skin for eczema?
What is the mechanism of late effects in adult testicular germ cell tumours?
What is the minimum effective dose of magnesium sulphate for women with pre-eclampsia, and when should it be started?
What is the most effective form of ADT (androgen deprivation therapy) for prostate cancer?
What is the most effective intervention for children with cleft lip/palate to minimise the impact of bullying?
What is the most effective sequence or combination of phosphate binders to control serum phosphate?
What is the most effective strategy to educate people with asthma and health professionals about managing the adverse effects of drug therapies?
What is the most effective treatment for peritoneal dialysis-associated peritonitis?
What is the most effective treatment for Vestibular migraine?
What is the most effective way of managing asthma triggers?
What is the most effective way of managing asthma with other conditions?
What is the most effective way to maintain weight loss in adults?
What is the most effective way to manage consultations and asthma control in adolescence and young people?
What is the most safe and effective monoclonal antibody treatment for people with eczema?
What is the natural history of incidental venous thromboembolism?
What is the optimal dialysis dose and frequency in Acute Kidney Injury?
What is the optimal dose and duration of anticoagulant therapy for superficial vein thrombosis or thrombophlebitis?
What is the optimal dose and duration of corticosteroid treatment for acute exacerbations of Chronic obstructive pulmonary disease
What is the optimal dosing and frequency of B12 injections to treat a person with pernicious anaemia?
What is the optimal duration of treatment (course length) in babies who receive antibiotics for confirmed early-onset neonatal infection?
What is the optimal level of blood glucose monitoring for the individual with diabetes?
What is the optimal management of partial epilepsy uncontrolled by a first choice anticonvulsant?
What is the optimal method for controlling glycaemia during labour and birth?
What is the optimal process for GP education and training for improved diagnosis and management of balance disorders?
What is the optimal set of guidelines for assessing children with tinnitus?
What is the optimal surveillance regime to improve ocular hypertension?
What is the optimal time between follow up appointments for men who have been treated for prostate cancer?
What is the optimal time of day to take epilepsy medication?
What is the optimal treatment of newly diagnosed rheumatoid arthritis?
What is the optimal use of combination treatments and the adverse effects of treatments for hyperkalaemia?
What is the optimal way of screening for and treating gestational diabetes?
What is the optimal way to take medication?
What is the optimum age for epilepsy surgery?
What is the optimum antibiotic treatment for acute chest syndrome in people with sickle cell disease?
What is the optimum dosage of oral steroids in children with asthma?
What is the optimum management of poor prognosis adult testicular germ cell tumours?
What is the optimum management of relapsed adult testicular germ cell tumours?
What is the optimum management of seminoma IIA/B in adults with testicular germ cell tumours?
What is the optimum pharmacological strategy for the management of patients with balance disorders?
What is the optimum pharmacological strategy for the management of patients with Ménière's disease? In particular, what are the effects of betahistine (including long term effects)?
What is the optimum timing and best immunosuppressive treatment for re-transplantation in patients with Post Transplant Lymphoproliferative Disorders?
What is the optimum timing to administer thromboprophylaxis during pregnancy and the puerperium?
What is the prevalence of late effects in adult testicular germ cell tumours?
What is the relationship between tinnitus and hearing loss?
What is the risk for CHD in patients with psoriasis, and does the risk change by severity and whether the risk varies by gender, race, or other concomitant risk factors?
What is the role of anti-viral agents in conjunction with chemotherapy in patients with Post Transplant Lymphoproliferative Disorders?
What is the role of complementary therapies in asthma management?
What is the role of diet in treating eczema, including how effective are nutritional supplements ?
What is the role of diet in treating eczema?
What is the role of diet in treating eczema?
What is the role of exercise in treating eczema?
What is the role of exercise to improve movement and decrease contractures and osteoporosis for those with dystrophic epidermolysis bullosa?
What is the role of food temperature in oral-esophageal lesions for patients with dystrophic epidermolysis bullosa?
What is the role of immunosuppression reduction versus chemotherapy in non-EBV related PTLD?
What is the role of immunosuppressive therapy in IgA Nephropathy?
What is the role of negative D--dimer in excluding deep vein thrombosis in high and moderate risk patients with a first negative ultrasound scan during pregnancy and the puerperium?
What is the role of PET scanning in detecting and monitoring Post Transplant Lymphoproliferative Disorders?
What is the role of physical activity restrictions to decrease the number of new lesions and increase quality of life for patients with dystrophic epidermolysis bullosa?
What is the role of topical corticosteroids in treatment of dystrophic epidermolysis bullosa?
What is the safety and efficacy of botulinum toxin compared with antimuscarinics in people with neurogenic lower urinary tract dysfunction?
What is the safety and efficacy of botulinum toxin compared with usual care in people with neurogenic lower urinary tract dysfunction?
What is the safety and efficacy of more recently developed antimuscarinics compared with placebo in the treatment of neurogenic lower urinary tract dysfunction?
What is the specificity and sensitivity of anti-cyclic citrullinated peptide in diagnosing early rheumatoid arthritis
What is the therapeutic role of aliskiren in proteinuria reduction?
What is the utility of FRAX and QFracture in adults receiving bone protective therapy?
What is the utility of FRAX and QFracture in detecting risk of fragility fracture in adults living in residential care?
What is the utility of FRAX and QFracture in detecting risk of fragility fracture in adults with secondary causes of osteoporosis?
What is the value of complementary medicines such as Buteyko method for people with asthma?
What is the value of using inhaled steroids continuously, versus a short course of oral steroids when the need arises if one doesn't have regular asthma attacks?
What key factors ensure people continue to walk or cycle in the long term (over a year)? How do individual interventions (such as follow-up or goal-setting) interact with environmental factors (such as distance, perception of danger or provision of facilities) in encouraging people to continue to walk or cycle?
What key factors influence differences in walking and cycling behaviour among different groups ? and what are the implications for interventions aiming to achieve population-level change and reduce inequalities?
What key factors influence the effectiveness of population-level or whole-area approaches to encouraging walking or cycling?
What makes self management successful for some people with type 1 diabetes and not others?
What management strategies are more effective than a usual model of audiological care in improving outcomes for people with tinnitus?
What measures can decrease the appearance of oral lesions for patients with dystrophic epidermolysis bullosa?
What medication could be used to help achieve regular bowel movements for Lymphocytic Ganglionitis?
What organisational mechanisms can ensure interventions to improve the social and emotional wellbeing and 'readiness for school' of vulnerable children aged under 5 years are effectively implemented?
What other medicines are safe when you have asthma and a cold or need pain relief?
What peak flow scores indicate caution, and then alarm, for a person with asthma, and when would I need to review my medication and/or go back to the asthma nurse?
What precautions do I need to consider as a person with asthma when flying?
What role does patient preference play in deciding which inhaler to prescribe for someone with asthma? Does this improve compliance and effectiveness?
What role does positron emission tomography/computed tomography have in management of late relapses in adults with testicular germ cell tumours?
What role does positron emission tomography/computed tomography have in prediction of response to chemotherapy in adults with testicular germ cell tumours?
What role might alternative medicine (herbal and homeopathic medicine) play in the treatment of dystrophic epidermolysis bullosa?
What role might Cetuximab play in the treatment of squamous cell carcinoma in patients with dystrophic epidermolysis bullosa?
What role might chemotherapy treatments play in treating vitiligo?
What role might food allergy tests play in treating eczema?
What role might gene therapy play in the treatment of vitiligo?
What role might growth hormone play in decreasing growth delay and puberty delayed in patients with dystrophic epidermolysis bullosa?
What role might immunotherapy e.g. to house dust mite have in treating eczema?
What role might skin grafts play in the treatment of eczema?
What role might stem cell therapy and bone marrow transplantation play in treating patients with dystrophic epidermolysis bullosa?
What role might stem cell therapy play in treating vitiligo?
What role might tissue engineering have in treating wounds in patients with dystrophic epidermolysis bullosa?
What self-help actions can aid recovery from treatment for prostate cancer?
What should be the sequence of acne therapy (first-line, second-line, and third-line)?
What should you do if you forget to take your epilepsy medication?
What specific type of diet is effective in reducing tinnitus symptoms?
What strategies /interventions have been investigated to improve compliance for people with asthma with: medication regimens; self-management practices and general asthma health promoting behaviour?
What strategies are effective in improving uptake of and engagement with interventions for conduct disorders?
What strategies are most effective for long-term maintenance of healthy weight or reduced weight following initial treatment of obesity?
What surgical outcomes are important to patients with cleft lip/palate and are they met?
What techniques could be developed to check blood sugar levels other than finger prick testing?
What tests should be used after a positive biopsy result to assess spread outside the prostate capsule?
What therapy can reduce neurological pain triggered by urinary incontinence in multiple sclerosis?
What treatments are available for children with asthma other than medications?
What treatments are available for hypergranulation tissue for patients with dystrophic epidermolysis bullosa?
What treatments are available for nail disease in patients with dystrophic epidermolysis bullosa?
What treatments are available to decrease smell for patients with dystrophic epidermolysis bullosa?
What treatments are best for insomnia whilst taking antipsychotic drugs for schizophrenia?
What treatments are effective for pyoderma gangrenosum?
What treatments are effective in managing neuropathy?
What treatments are helpful for diabetic hand complications?
What treatments help manage obesity in children and adults and what training do staff need to deliver the treatments, making them effective and sustainable?
What treatments, including psychological support services, are effective to manage the psychological effects of type 1 diabetes?
What type of digital hearing aid or amplification strategy provides the most effective tinnitus relief?
What type of inhaler is the most effective for different age groups?
What type of patient (children and adults) and health professional education is most effective in gaining asthma control?
What types of home-based intervention are effective in promoting the social and emotional wellbeing of vulnerable children aged under 5 years without involving the parents?
What types of psychological intervention (individual therapy, community or school based) and at what time (from diagnosis to adulthood) are most helpful for patients with cleft lip/palate and their families?
What will be the potential benefits to people with diabetes of Smart insulin?
What would be the best way to deal with comorbid illnesses for people with prostate cancer?
Wheat-based oral rehydration solution for acute watery diarrhoea
Wheelchairs for children under 12 with physical impairments
When a patient on anticoagulation is to undergo an invasive procedure, how soon should anticoagulation be stopped prior to the procedure, and how long afterwards should it be restarted?
When clean running water is not available, what is the clinical and cost effectiveness of using wipes, gels, handrubs or other products to remove visible contamination?
When is the best time to consider depigmentation?
When managing patients with proximal femoral fracture, which approach to pre-hospital pain management achieves the most effective analgesia; morphine sulphate, ketamine or femoral nerve block?
When should a viral infection prompt an increase in asthma medication in children?
When should antihistamine treatment be stopped for people with eczema?
When should I go to see the GP when having an asthma attack for emergency steroids?
When would it be worthwhile having oxygen or other emergency equipment at home to treat asthma?
Whether addition of bladder training to other forms of management of overactive bladder symptoms (including incontinence) is useful
Whether calcium supplementation for prevention of pre-eclampsia influences the health of the womens' children.
Whether one method of administration of anticholinerigic drugs for Overactive Bladder Syndrome, is better than another, and if so when.
Which adverse effects from antipsychotic drugs do patients find most difficult to cope with?
Which anticholinergic drug for overactive bladder symptoms
Which anticholinergic drug for overactive bladder symptoms in adults
Which anticholinergic drug for overactive bladder symptoms in adults
Which are the most beneficial types of work-related day-time activities for schizophrenia and other serious mental health problems?
Which bacterial species in the human intestine are responsible for the generation of trimethylamine?
Which binders are most effective in controlling serum phosphate in adults with stage 4 or 5 CKD who are not on dialysis?
Which binders are most effective in controlling serum phosphate in children with stage 4 or 5 chronic kidney disease (CKD), including those who are on dialysis?
Which bladder management strategies are most effective for a neurogenic bladder in Spina Bifida?
Which care measure is more effective to hasten healing and decrease complications, moist wound care or dry care for patients with dystrophic epidermolysis bullosa?
Which care measure is more effective to hasten healing and decrease complications, to drain bullae or to leave them untouched for patients with dystrophic epidermolysis bullosa?
Which care measure is more effective to improve healing and decrease infections, daily care or care on alternate days for patients with dystrophic epidermolysis bullosa?
Which cases of superficial vein thrombosis or thrombophlebitis require imaging to exclude concurrent deep vein thrombosis?
Which chemicals may irritate skin for someone with eczema?
Which components of nurse follow up produce the greatest benefits for patients with heart failure
Which drug provides better protection for preventing the progression of diabetic kidney disease: angiotension converting enzyme inhibitors or antiotensin II receptor antagonists?
Which emollient is the most effective and safe in treating eczema?
Which ethnic, religious, language or racial identity factors hinder engagement for people with schizophrenia from Black and Minority Ethnic groupss?
Which factors influence adherence to treatments for psoriatic arthritis?
Which form of vestibular rehabilitation is most effective for unilateral peripheral vestibular dysfunction?
Which hormone therapy, continuous or intermittent, is more effective in treating prostate cancer?
Which individuals with schizophrenia would most benefit from Family Interventions?
Which insulins are safest and have the fewest adverse effects?
Which interventions for other communicable diseases could be used to encourage people at increased risk of hepatitis B and C infection to take up the offer of testing and treatment?
Which is best for the treatment of eczema; sedating or non-sedating antihistamines?
Which is best treatment to apply to the skin for irritant hand eczema, steroids or moisturisers?
Which is better in treating eczema; ultraviolet light treatment or oral immunosuppresants treatment (e.g. azathioprine, methotrexate etc)?
Which is more effective azathioprine or topical treatments for eczema?
Which is more effective in the management of eczema: education programmes, GP care, nurse-led care, dermatologist-led care or multi disciplinary care?
Which is more effective; antimicrobials (antibiotics, antifungals and antiseptics) applied to the skin or taken by mouth?
Which is safer and more effective for treating eczema; topical steroids or calcineurin inhibitors?
Which is the best and safest complementary therapy to help patients with eczema?
Which is the best and safest way to use antimicrobial bath additives e.g. salt and bleach to treat eczema?
Which is the best psychotherapy for the treatment of psychosis?
Which is the best shampoo for someone with eczema?
Which is the best treatment, heparin or thrombolysis in high-risk pulmonary embolism patients?
Which is the best way for people with eczema to wash: frequency of washing, water temperature, bath versus shower?
Which is the best way to manage aggression in schizophrenia?
Which is the most effective cerumenolytic for ear syringing for ear wax removal?
Which is the most effective treatment in end-stage renal failure: haemodiafiltration or haemodialysis?
Which management strategies are most effective for the management of neurogenic bladder following spinal cord injury?
Which medications have proven to be effective in tinnitus management?
Which non-corticosteroid treatments are effective for nephrotic syndrome in children?
Which patients benefit most from cardiac resynchronization therapy (CRT) or cardiac resynchronization therapy device and defibrillator (CRT-D)
Which patients benefit most from Implanted Arrhythmia Controlled Devices (ICD) implantation
Which patients with solid tumours or lymphoma may benefit from antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy?
Which protocols of cleft care produce the best results?
Which retention gauze is more effective to increase healing rate and prevent infection for patients with dystrophic epidermolysis bullosa?
Which risk factors for early-onset neonatal infection, clinical symptoms and signs of infection, and laboratory investigations should be used to identify babies who should receive antibiotics?
Which should be applied first when treating eczema, emollients or topical steroids?
Which topical combination therapy is best for mild to moderate facial acne?
Which treatment is more effective for vitiligo: calcineurin inhibitors (e.g. tacrolimus, pimecrolimus) or light therapy?
Which treatment is more effective for vitiligo: calcineurin inhibitors (e.g. tacrolimus, pimecrolimus) or steroid cream?
Which treatment is more effective for vitiligo: calcineurin inhibitors (e.g. tacrolimus, pimecrolimus) or steroid creams/ointments?
Which treatment is more effective for vitiligo: calcineurin inhibitors (e.g. tacrolimus, pimecrolimus) or vitamin D analogues (e.g. calcipotriol)?
Which treatment is more effective for vitiligo: laser or other light therapy?
Which treatment is more effective for vitiligo: light therapy or calcineurin inhibitors (e.g. tacrolimus, pimecrolimus)?
Which treatment is more effective for vitiligo: melagenina or UV light?
Which treatment is more effective for vitiligo: psoralen taken by mouth or psoralen cream/ointment?
Which treatment is more effective for vitiligo: steroid cream or a different cream that suppresses the immune system?
Which treatment is more effective for vitiligo: steroid creams/ointments or light therapy?
Which treatment is more effective to increase quality of life and reduce pain in children with dystrophic epidermolysis bullosa : self wound care, or care by a carer?
Which treatment options are most effective in the management of nocturnal enuresis?
Which treatments are more effective for improving the quality of life of patients with vitiligo: psychological interventions or treatments to aid repigmentation?
Which type of insulin is most effective?
Which types of psychosocial interventions are effective for people with diabetes?
Which women benefit from thromboprophylaxis during pregnancy and the puerperium?
Who is the best person within a multi-disciplinary team to treat people when they first present with seizures?
Who is the best person within a multi-disciplinary team to treat people whose seizure pattern is changing?
Who should be offered psychosocial care: people with diabetes of all ages or just those of a certain age?
Who should be offered psychosocial care: those who have poor diabetes management or all people with diabetes?
Whole body cooling versus selective head cooling for newborns with hypoxic ischaemic encephalopathy
Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases
Whole brain radiotherapy for the treatment of multiple brain metastases
Whole brain radiotherapy for the treatment of newly diagnosed multiple brain metastases
Whole-body vibration training for patients with neurodegenerative disease
Why are the best moisturisers always oily and greasy for use by people with eczema?
Why do patients not have nebulisers prescribed by their GP to use at home to prevent asthma attacks, and possibly avoid admission to hospital?
Why do some treatments for eczema applied to the skin stop working?
Why is the better (but more expensive) insulin pumps and continuous glucose monitoring systems not more available for the treatment of type 1 diabetes, even though they would save the NHS money in the long term due to lower incidence of related conditions/complications?
Will avoiding low energy saving lightbulbs improve my epilepsy?
Will breast feeding reduce the chances of a baby developing atopic eczema?
Will changing location to a warmer climate help children's asthma?
Will education and training of clinicians improve guideline adherence and outcomes for patients with attention deficit-hyperactivity disorder (ADHD)
Will exercise affect my asthma?
Will how I position myself to get to sleep help improve my asthma?
Will increasing the knowledge and awareness of hepatitis B and C among the general public have an impact on the uptake of testing and treatment?
Will noscapine provide a treatment or control for prostate cancer progression in post prostatectomy patients?
Will staging of prostate cancer patients be better using MRI Scans and will this improve treatment outcomes?
Will taking steroids for asthma cause me long term health problems?
Will the skin treatment differ for each type of eczema?
Will treating psychological distress including depression and anxiety in adults with psoriasis and psoriatic arthritis have an effect on disease severity and flare-ups?
Withdrawal of medications for sleep-related epilepsy
Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and psychological symptoms in older people with dementia
Work arrangements for sustaining employment in workers with HIV
Workload and surgeon's specialty for outcome after colorectal cancer surgery
Workplace interventions for neck pain in workers
Workplace interventions for treatment of occupational asthma
Workplace pedometer interventions for increasing physical activity
Would a comprehensive biochemical screening test for trimethylaminuria help patients?
Would a screening programme for prostate cancer for men age 50 or above benefit outcomes?
Would a screening programme for prostate cancer for men younger than 50 benefit outcomes?
Would a 'whole life' scoring tool predict the risk of developing prostate cancer and would using it allow me to make choices that would reduce my risk of developing prostate cancer?
Would an antibiotic (oral or topical) devoid of immunomodulatory effects show any therapeutic benefit in acne vulgaris?
Would an awareness programme targeted at African/Caribbean men improve outcomes for men of this ethnic group?
Would changes in my antipsychotic medication help my concentration improve?
Would complications of pernicious anaemia, such as peripheral neuropathy or sub acute combined degeneration of the spinal cord, be avoided by more flexible dosing of B12, targeted to the patients symptoms?
Would day care intravenous therapy speed discharge and avoid readmission in patients with chronic heart failure?
Would delivery of radiotherapy in fewer and larger doses (hypofractionation) improve prostate cancer outcomes?
Would dietary control of animal fats, and particularly dairy products, help reduce my risk of, or provide a protective effect against my prostate cancer getting worse?
Would earlier chemotherapy improve the outcomes of treatment for prostate cancer patients?
Would GPs benefit from a comprehensive and standardised guideline for tinnitus assessment, management and onwards referral?
Would improving surgical techniques help improve outcomes for patients with prostate cancer?
Would introducing new treatments early on improve outcomes for people with prostrate cancer?
Would knowing about other early symptoms of prostate cancer, other than urinary symptoms, improve the outcomes of treatment?
Would patients with pernicious anaemia have better outcomes if they had access to other forms of injections of B12: such as cyanocobalamin or methylcobalamin?
Would patients with tinnitus benefit from a comprehensive and standardised set of diagnostic tests?
Would people with tinnitus benefit from having a definitive list of medicines that are proven to either to cause or make pulsatile tinnitus symptoms worse?
Would prostate cancer screening targeted at high risk groups, i.e. those with positive family history, and ethnic minorities with higher rates, improve the outcomes of treatment in these groups?
Would prostate cancer screening targeted at high risk groups, i.e. those with positive family history, and ethnic minorities with higher rates, improve the outcomes of treatment in these groups?
Would restoration of testosterone levels prevent or delay onset of hormone independent prostate cancer?
Would screening of men with a female family history of breast and/or ovarian cancer reduce their risk of being wrongly diagnosed with prostate cancer, and over- or under-treated?
Would screening the family members of patients who have cancer identify those who go on to develop prostate cancer?
Would targeted screening in specific occupations and residential groups reduce prostate cancer risk?
Would the introduction of targeted screening for men with a family history of prostate cancer help with early diagnosis and improve outcomes?
Would training support staff on issues such as state benefits improve the uptake of the same for men and their partners with prostate cancer?
Wound cleansing for pressure ulcers
Wound drainage after plastic and reconstructive surgery of the breast
Wound drains after incisional hernia repair
Wound drains following thyroid surgery
Wound edge protectors to reduce surgical site infection in open addominal surgery
Written action plans for asthma in children
Xpert? MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults
Xuebijing for paraquat poisoning
Xylitol for preventing acute otitis media in children up to 12 years of age
Yoga for asthma
Yoga for epilepsy
Yoga for haematological malignancies
Yoga for secondary prevention of coronary heart disease
Yoga for the primary prevention of cardiovascular disease
Yoga for the treatment of mild multiple sclerosis
Zinc for age-related macular degeneration to prevent progression
Zinc for the common cold
Zinc for the prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection
Zinc or chelator agents for initial monotherapy in Wilson's disease
Zinc supplementation as an adjunct to antibiotics in the treatment of pneumonia in children 2 to 59 months of age
Zinc supplementation for improving pregnancy and infant outcome
Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months
Zinc supplementation for the promotion of growth and prevention of infections in infants less than six months of age
Zinc supplementation for tinnitus
Zinc supplements for preventing otitis media
Zonisamide for essential tremor
Zuclopenthixol acetate for acute schizophrenia and similar serious mental illnesses