UK Database of Uncertainties about the Effects of Treatments (DUETs) Resource List

"As needed" versus continuously scheduled antimuscarinic therapy for urinary incontinence
(1-3)B-D-glucan testing for the detection of invasive fungal infections in immunocompromised patients
11C-PIB-PET for the early diagnosis of Alzheimer?s disease dementia and other dementias in people with mild cognitive impairment (MCI)
11C-PIB-PET for the early diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
308nm excimer laser for repigmentation in vitiligo
308nm excimer laser plus topical calcipotriol for repigmentation in vitiligo
308nm excimer laser plus topical hydrocortisone 17-butyrate for repigmentation in vitiligo
5-ASA for management of symptomatic uncomplicated diverticular disease (SUDD)
5-Fluorouracil for glaucoma surgery
A 35 yr old with DVT has just stopped warfarin after 6 months. Is there any evidence for him taking Aspirin (75mg-300mg) life-long to prevent recurrence?
A comparison of endoscopic and surgical treatment of strictures in patients with Crohn's disease
A co-ordinated approach of primary and secondary care in the early diagnosis and management of schizophrenia
A review of the effectiveness of oral health promotion activities among elderly people
A systematic review of endoscopic scoring indices for evaluation of disease activity in Crohn's disease
A therapeutic-only versus prophylactic platelet transfusion strategy for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation
Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV
Abatacept for rheumatoid arthritis
Abdominal decompression for suspected fetal compromise/pre-eclampsia
Abdominal decompression in normal pregnancy
Abdominal drainage after appendectomy for complicated appendicitis
Abdominal drainage versus no drainage post gastrectomy for gastric cancer
Abdominal lift for laparoscopic cholecystectomy
Abdominal surgical incisions for caesarean section
Absence of carious lesions at margins of glass-ionomer and amalgam restorations
Acamprosate for alcohol dependence
Acceptability, efficacy and safety of pharmacological interventions for cocaine dependence: an overview of Cochrane reviews
Accommodative intraocular lens versus standard monofocal intraocular lens implantation in cataract surgery
Accuracy of assessment instruments for patients' competence to consent to medical treatment or research
ACE inhibitors for the reduction of portal pressure in Child-Pugh class A cirrhosis
Acellular vaccines for preventing whooping cough in children
Acetaminophen (paracetamol) for the common cold in adults
Acetylcholinesterase inhibitor treatment for myasthenia gravis
Acetylcholinesterase inhibitors and memantine for the treatment of psychotic symptoms in dementia over six months
Acetylcholinesterase inhibitors for schizophrenia
Acetylcysteine and carbocysteine for acute upper and lower respiratory tract infections in paediatric patients without chronic broncho-pulmonary disease
Acetyl-L-carnitine for the treatment of diabetic polyneuropathy
Acid reflux treatment for hoarseness
Aclidinium bromide for stable chronic obstructive pulmonary disease
Acoustic CR Neuromodulation is a commercial device for 'brain training'. Is it effective for people with tinnitus?
Action plans for chronic obstructive pulmonary disease
Action plans with limited patient education only for exacerbations of chronic obstructive pulmonary disease
Active case finding in contacts of people with tuberculosis
Active chest compression-decompression for cardiopulmonary resuscitation
Active cycle of breathing technique for cystic fibrosis
Active management of spontaneous labour versus routine care in women who have had one or more previous caesarean sections
Active placebos versus antidepressants for depression
Active specific immunotherapy for malignant melanoma
Active versus passive parental consent for improving participant recruitment and outcomes in studies targeting children
Activities and occupations on inpatient mental health wards
Activity and prosthesis failure for people with arthritis of the hip.
Activity restriction for short-term and medium-term outcomes following mild traumatic brain injury
Acupoint stimulation for postoperative ileus ?following gastrointestinal surgery
Acupressure for motion sickness
Acupuncture and assisted reproductive technology
Acupuncture and moxibustion for acne
Acupuncture and related interventions (acupressure, laser therapy or electrostimulation) for smoking cessation
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome
Acupuncture and related interventions for treating plantar heel pain in adults
Acupuncture for acute hordeolum
Acupuncture for acute management and rehabilitation of traumatic brain injury
Acupuncture for adults with type 2 diabetes mellitus
Acupuncture for asthma
Acupuncture for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents
Acupuncture for autism spectrum disorders (ASD)
Acupuncture for Bell's palsy
Acupuncture for bladder dysfunction after spinal cord injury
Acupuncture for chronic asthma
Acupuncture for chronic constipation
Acupuncture for depression
Acupuncture for epilepsy
Acupuncture for female subfertility
Acupuncture for glaucoma
Acupuncture for hypoxic ischemic encephalopathy in neonates
Acupuncture for induction of labour
Acupuncture for insomnia
Acupuncture for Ménière's Syndrome
Acupuncture for menopausal hot flushes
Acupuncture for mumps in children
Acupuncture for myofascial pain
Acupuncture for nocturnal enuresis
Acupuncture for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Acupuncture for pain in endometriosis
Acupuncture for polycystic ovarian syndrome
Acupuncture for primary hypercholesterolaemia
Acupuncture for rheumatoid arthritis
Acupuncture for schizophrenia
Acupuncture for schizophrenia
Acupuncture for slowing the progression of myopia in children and adolescents
Acupuncture for stress urinary incontinence in adults
Acupuncture for tinnitus
Acupuncture for treating acute ankle sprains in adults
Acupuncture for treating fibromyalgia
Acupuncture for treating irradiation-induced xerostomia in head and neck cancer
Acupuncture for treatment of irritable bowel syndrome
Acupuncture for treatment-related side effects in women with breast cancer
Acupuncture for urinary incontinence in adults without neurological disease
Acupuncture for xerostomia
Acupuncture in poststroke rehabilitation
Acupuncture or acupressure for pain management in labour
Acupuncture vs routine care for tension-type headache
Acupuncture vs sham treatments for tension-type headache
Acupuncture, QiGong, graded exercise, or other alternative therapies for Lyme disease
Acute day hospitals compared to other acute service provision, such as crisis resolution and home treatment teams for serious mental illness
AD-8 for diagnosis of dementia across a variety of healthcare settings
Adalimumab efficacy and safety for fiztulising Crohn's disease after infliximab treatment failure
Adaptation of shift work schedules for preventing and treating sleepiness and sleep disturbances caused by shift work
Add-back therapy with GnRH analogues for uterine fibroids
Adding a newer anti-anginal drug to a calcium channel blocker in stable angina?
Adding leukotriene antagonists to inhaled corticosteroids in people with mild to moderate, persistent asthma
Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma
Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma
Addition of inhaled anticholinergics to beta2-agonists for children with acute asthma in hospital
Addition of intravenous aminophylline to inhaled beta2-agonists in adults with acute asthma
Addition of intravenous beta2-agonists to inhaled beta2-agonists for acute asthma
Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma
Additional bedtime H2-receptor antagonist for the control of nocturnal gastric acid breakthrough
Additional exercise therapy for the recovery of function after stroke
Additional intensive physiotherapy and/or occupational therapy after hip fracture
Additional plerixafor to granulocyte colony-stimulating factors for haematopoietic stem cell mobilisation for autologous transplantation in malignant lymphoma or multiple myeloma patients
Additional technologies to enhance angioplasty for infrainguinal peripheral arterial occlusive disease
Adenosine A2A receptor antagonist istradefylline for levodopa-induced complications in Parkinson's disease
Adenosine and verapamil for no-reflow during primary percutaneous coronary intervention in people with acute myocardial infarction
Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2 diabetes mellitus
Adenotonsillectomy for obstructive sleep apnoea in children
Adherence compounds in embryo transfer media for assisted reproductive technologies
Adhesion prevention agents for gynaecological surgery: an overview of Cochrane reviews
Adjunctive antioxidants for bipolar disorder
Adjunctive antithyroid drugs in radioiodine therapy for hyperthyroidism
Adjunctive hyperbaric oxygen for necrotizing fasciitis
Adjunctive surgical procedures for accelerating tooth movement in patients undergoing orthodontic treatment
Adjustable versus non-adjustable sutures for strabismus
Adjusting the pH of lidocaine for reducing pain on injection
Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer
Adjuvant antiviral therapy for recurrent respiratory papillomatosis
Adjuvant chemotherapy after concurrent chemoradiation for locally advanced cervical cancer
Adjuvant chemotherapy for advanced endometrial cancer
Adjuvant chemotherapy for endometrial cancer after hysterectomy
Adjuvant chemotherapy for small intestine adenocarcinoma
Adjuvant corticosteroids for reducing death in neonatal bacterial meningitis
Adjuvant gonadotropin-releasing hormone analogues for the prevention of chemotherapy induced premature ovarian failure in premenopausal women
Adjuvant platinum-based chemotherapy for early stage cervical cancer
Adjuvant radiotherapy and/or chemotherapy after surgery for uterine carcinosarcoma
Adjuvant radiotherapy following radical prostatectomy for pathologic T3 or margin-positive prostate cancer
Adjuvant radiotherapy following radical prostatectomy for prostate cancer
Adjuvant radiotherapy for stage I endometrial cancer
Adjuvant therapy for completely resected stage II colon cancer
Adjuvant therapy for the treatment of advanced borderline ovarian tumours
Adjuvant treatment of anaplastic oligodendrogliomas and oligoastrocytomas
Adrenaline auto-injectors for the treatment of anaphylaxis with and without cardiovascular collapse in the community
Adrenaline with lidocaine for digital nerve blocks
Adrenergic drugs for urinary incontinence in adults
Adrenergic drugs for urinary incontinence in comparision with alternative approaches to the care of people with stress urinary incontinence
Advance care planning for haemodialysis patients
Advance misoprostol distribution for preventing and treating postpartum haemorrhage
Advance treatment directives for people with severe mental illness
Advanced sperm selection techniques for assisted reproduction
Advanced training in trauma life support for ambulance crews
Advanced trauma life support training for ambulance crews
Advanced trauma life support training for hospital staff
Advantages and disadvantages of alternative types of oestrogen therapy in treating post-menopausal women with urinary incontinence.
Adventitial sheathotomy in branch retinal vein occlusion
Adverse effects in women taking Pentoxifylline for the treatment of endometriosis?
Adverse effects of anti-epileptic drugs medication in pregnancy
Adverse effects of biologics: a network meta-analysis and Cochrane overview
Advising patients to increase fluid intake for treating acute respiratory infections
Advocacy, domestic abuse recovery programmes, perpetrator programmes, and psychological or social interventions modified for domestic violence and abuse
Agomelatine versus other antidepressive agents for major depression
Air pollution: no evidence was identified regarding asthma and indoor air pollutants, such as volatile organic compounds, formaldehyde or nitrogen oxide
Air versus saline in the loss of resistance technique for identification of the epidural space
Airway clearance techniques for bronchiectasis
Airway clearance techniques for chronic obstructive pulmonary disease
Airway clearance techniques for cystic fibrosis: an overview of Cochrane systematic reviews
Alanine Aminotransferase (ALT) values for children and young people with chronic hepatitis B
Alarms, desmopressin or tricyclic drug treatment as the first line management of nocturnal enuresis in children
Alcohol and drug screening of occupational drivers for preventing work-related injury
Alcohol intake reduction for controlling hypertension
Aldosterone antagonists for preventing the progression of chronic kidney disease
Aldosterone blockers for heart failure
Alemtuzumab for multiple sclerosis
Alemtuzumab for patients with chronic lymphocytic leukaemia
Alemtuzumab versus interferon beta 1a for relapsing-remitting multiple sclerosis
Alexander technique for chronic asthma
Alginate dressings for healing diabetic foot ulcers
Alginate dressings for treating pressure ulcers
Alginate dressings for venous leg ulcers
Alginate dressings for venous leg ulcers
Allergen injection immunotherapy for perennial allergic rhinitis
Allergen-specific oral immunotherapy for peanut allergy
Allicin for Lyme disease
Allogeneic hematopoietic cell transplantation for adult acute lymphoblastic leukemia (ALL) in first complete remission
Allogeneic stem cell transplantation versus conventional therapy for advanced primary cutaneous T-cell lymphoma
Allogeneic stem cell transplantation with matched sibling donor versus autologous stem cell transplantation for newly diagnosed Multiple Myeloma
Allograft versus autograft for reconstruction of anterior cruciate ligament rupture in adults
Allopurinol for preventing mortality and morbidity in newborn infants with hypoxic-ischaemic encephalopathy
Almitrine-Raubasine combination for dementia
Aloe vera for prevention and treatment of infusion phlebitis
Aloe vera for treating acute and chronic wounds
Alpha blockers for removal of urethral catheter after acute urinary retention in men
Alpha2 adrenergic agonists for attention deficit hyperactivity disorder (ADHD)
Alpha-2 adrenergic agonists for the prevention of shivering following general anaesthesia
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients
Alpha2-adrenergic agonists for the management of opioid withdrawal
Alpha-blockers as medical expulsive therapy for ureteral stones
Alpha-foetoprotein and/or liver ultrasonography for screening of hepatocellular carcinoma in patients with chronic hepatitis B
Alprazolam for depression
Alprazolam for essential tremor
Altered blood pH for Lyme disease
Altered dietary salt intake for chronic kidney disease
Altered dietary salt intake for preventing and treating diabetic kidney disease
Alternating current cranial electrotherapy stimulation (CES) for depression
Alternating different antibiotics for Lyme disease
Alternative agents versus prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation
Alternative and complementary therapies for psoriasis
Alternative injectable materials for vocal fold medialisation in unilateral vocal fold paralysis
Alternative testing sites to increase the number of people who are tested and treated for hepatitis B and C
Alternative versus conventional institutional settings for birth
Alveolar ridge preservation techniques for oral implant site development
Amantadine and rimantadine for influenza A in children and the elderly
Amantadine for depression
Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome
Ambulatory oxygen for people with chronic obstructive pulmonary disease who are not hypoxaemic at rest
Amifostine for salivary glands in high-dose radioactive iodine treated differentiated thyroid cancer
Amino acid, fat emulsion and energy supplementation for severe pneumonia in the elderly
Aminoadamantanes for chronic hepatitis C
Aminoadamantanes versus other antiviral drugs for chronic hepatitis C
Aminophylline for bradyasystolic cardiac arrest in adults
Aminosalicylates for induction of remission or response in Crohn's disease
Amitriptyline for depression
Amitriptyline for neuropathic pain and fibromyalgia in adults
Amitriptyline versus placebo for major depressive disorder
Amnioinfusion for improving fetal outcomes after preterm prelabour rupture of membranes
Amnioinfusion for meconium-stained liquor in labour
Amnioinfusion for potential or suspected umbilical cord compression in labour
Amnioinfusion for third trimester preterm premature rupture of membranes
Amniotic membrane transplantation for acute ocular burns
Amniotomy for shortening spontaneous labour
Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents
Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function
Amplification for auditory neuropathy
Amplification with hearing aids for patients with tinnitus and co-existing hearing loss
An overview of reviews evaluating the effectiveness of financial incentives in changing healthcare professional behaviours and patient outcomes
Anaesthesia for evacuation of incomplete miscarriage
Anaesthesia for treating distal radial fracture in adults
Anaesthetic and sedative agents used for electrical cardioversion
Anaesthetic regimens for day-procedure laparoscopic cholecystectomy
Anakinra compared to other biological therapies for rheumatoid arthritis
Analgesia for amniocentesis or chorionic villus sampling
Analgesia for forceps delivery
Analgesia for patients undergoing shockwave lithotripsy for urinary stones
Analgesia for relief of pain due to uterine cramping/involution after birth
Anatomical iliofemoral bypass versus extra-anatomical crossover grafting for symptomatic unilateral iliac disease
Andrenoceptor agonists for urinary incontinence
Androgens (dehydroepiandrosterone or testosterone) in women undergoing assisted reproduction
Angiogenesis inhibitors for the treatment of ovarian cancer
Angiogenesis-inhibitors for metastatic thyroid cancer
Angioplasty versus bare metal stenting for superficial femoral artery lesions
Angioplasty versus stenting for subclavian artery stenosis
Angiotensin converting enzyme (ACE) gene polymorphism (ACEI/D) in hypertensive adults with ACE inhibitor-induced cough
Angiotensin receptor blockers for heart failure
Angiotensin receptor blockers for heart failure
Angiotensin receptor blockers for the reduction of portal pressure in Child-Pugh class A cirrhosis
Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in peritoneal dialysis patients
Angiotensin-converting enzyme inhibitors for congestive heart failure in children
Animal research suggests that auditory 'brain training' combined with vagus nerve stimulation might influence tinnitus. Is this treatment effective for people with tinnitus?
Animal-assisted therapy for people with serious mental illness
Ankle brachial index for the diagnosis of symptomatic peripheral arterial disease
Ankle foot orthosis for walking in stroke rehabilitation
Annual Chest X-Rays in successfully treated cases of Head & Neck cancer
Antenatal breast milk expression by women with diabetes for improving infant outcomes
Antenatal breastfeeding education for increasing breastfeeding duration
Antenatal cardiotocography for fetal assessment
Antenatal care programmes to reduce infant mortality and preterm birth in socially disadvantaged and vulnerable women in high-income countries.
Antenatal dietary advice and supplementation to increase energy and protein intake
Antenatal immunoglobulin for fetal red blood cell alloimmunization
Antenatal interventions for preventing the transmission of cytomegalovirus (CMV) from the mother to fetus during pregnancy and adverse outcomes in the congenitally infected infant
Antenatal interventions for reducing weight in obese women for improving pregnancy outcome
Antenatal perineal massage for reducing perineal trauma
Antenatal screening for haemoglobinopathies in primary care: a cluster randomised trial to inform a simulation model
Anterior approach versus conventional liver resection for hepatocellular carcinoma
Anthracycline-containing regimens for treatment of follicular lymphoma in adults
Anti-adhesion molecules for Crohn's disease
Anti-adhesion therapy following operative hysteroscopy for treating female subfertility
Anti-angiogenic therapies for metastatic colorectal cancer in patients with cardiovascular disease or a history of prior thromboembolic events
Antiangiogenic therapy with anti-vascular endothelial growth factor (anti-VEGF) modalities to treat diabetic macular oedema
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema
Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration
Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation
Antibacterial agents in composite restorations for the prevention of dental caries
Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis
Antibiotic and other lock treatments for tunnelled central venous catheter-related infections in children with cancer
Antibiotic gels for the prevention of Lyme disease in patients with tick bites
Antibiotic lock for the prevention of catheter-related sepsis in neonates
Antibiotic prophylaxis for hernia repair
Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy
Antibiotic prophylaxis for preventing burn wound infection
Antibiotic prophylaxis for preventing infection in open finger fractures
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery
Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures
Antibiotic prophylaxis for preventing post solid organ transplant tuberculosis
Antibiotic prophylaxis for short-term catheter bladder drainage in adults
Antibiotic prophylaxis for surgical site infection in patients undergoing liver transplantation
Antibiotic prophylaxis for the prevention of Methicillin resistant Staphylococcus aureus (MRSA) infections and related complications in surgical patients
Antibiotic prophylaxis for the prevention of methicillin-resistant Staphylococcus aureus (MRSA) related complications in surgical patients
Antibiotic prophylaxis for transrectal prostate biopsy
Antibiotic prophylaxis for transurethral urological procedures
Antibiotic regimens for management of intra-amniotic infection
Antibiotic regimens for the empirical treatment of newborn infants with necrotising enterocolitis
Antibiotic therapy for pelvic inflammatory disease (PID)
Antibiotic therapy for preventing infections in patients with acute stroke
Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) in non surgical wounds
Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds
Antibiotic therapy for the treatment of Methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds
Antibiotic therapy for treatment of infective endocarditis
Antibiotic therapy versus no antibiotic therapy for children aged two to 59 months with WHO-defined non-severe pneumonia and wheeze
Antibiotic treatment based on clinical suspicion for Lyme disease after a negative serological test
Antibiotic treatment based on clinical suspicion versus waiting for serology results in possible Lyme disease
Antibiotic treatment for Burkholderia cepacia complex in people with cystic fibrosis experiencing a pulmonary exacerbation
Antibiotic treatment for nontuberculous mycobacteria lung infection in people with cystic fibrosis
Antibiotic treatment for Stenotrophomonas maltophilia in people with cystic fibrosis
Antibiotic use for irreversible pulpitis
Antibiotics and antiseptics for venous leg ulcers
Antibiotics at dental implant placement to prevent complications
Antibiotics for acute bronchitis
Antibiotics for acute laryngitis in adults
Antibiotics for acute maxillary sinusitis in adults
Antibiotics for acute otitis media in children
Antibiotics for acute otitis media in children; effects on subgroups
Antibiotics for brain abscesses in people with cyanotic congenital heart disease
Antibiotics for chronic osteomyelitis in adults
Antibiotics for clinically diagnosed acute rhinosinusitis in adults
Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children
Antibiotics for community-acquired pneumonia in children
Antibiotics for exacerbations of chronic obstructive pulmonary disease
Antibiotics for gonorrhoea in pregnancy
Antibiotics for infection prevention after excision of the cervical transformation zone
Antibiotics for leptospirosis
Antibiotics for mastitis in breastfeeding women
Antibiotics for meconium-stained amniotic fluid in labour for preventing maternal and neonatal infections
Antibiotics for otitis media with effusion in children
Antibiotics for persistent cough or wheeze following acute bronchiolitis in children
Antibiotics for persistent nasal discharge (rhinosinusitis) in children
Antibiotics for preterm rupture of membranes
Antibiotics for preventing complications in children with measles
Antibiotics for preventing meningococcal infections
Antibiotics for preventing suppurative complications from undifferentiated acute respiratory infections in children under five years of age
Antibiotics for prolonged moist cough in children
Antibiotics for sore throat
Antibiotics for the common cold and acute purulent rhinitis
Antibiotics for the prophylaxis of bacterial endocarditis in dentistry
Antibiotics for trachoma
Antibiotics for treating acute chest syndrome in people with sickle cell disease
Antibiotics for treating bacterial vaginosis in pregnancy
Antibiotics for treating chronic osteomyelitis in adults
Antibiotics for treating community acquired pneumonia in people with sickle cell disease
Antibiotics for treating genital chlamydia trachomatis infection in men and non-pregnant women
Antibiotics for treating human brucellosis
Antibiotics for treating lower urinary tract infection in children
Antibiotics for treating osteomyelitis in people with sickle cell disease
Antibiotics for treating salmonella gut infections
Antibiotics for uncomplicated diverticulitis
Antibiotics in 'clean' foot ulcers in people with diabetes
Antibiotics plus colony stimulating factors versus antibiotics alone for the prevention of infections in cancer patients receiving myelosuppressive chemotherapy or haematopoetic stem cell transplantation
Antibiotics prior to amniotomy for reducing infectious morbidity in mother and infant
Antibiotics prior to embryo transfer in ART
Antibiotics to prevent complications following tooth extractions
Antibiotics to reduce post-tonsillectomy morbidity
Antibiotics versus control for toxoplasma retinochoroiditis
Antibiotics versus placebo for acute bacterial conjunctivitis
Antibody induction therapy for lung transplant recipients
Antibody induction versus corticosteroid induction for liver transplant recipients
Antibody induction versus corticosteroid induction for liver transplant recipients
Antibody induction versus placebo, no induction, or another type of antibody induction for liver transplant recipients
Antibody induction versus placebo, no induction, or another type of antibody induction for liver transplant recipients
Antibody therapies for lymphoma in children
Anticholinergic drugs for nocturnal enuresis (oxybutynin, tolterodine, hyoscyamine)
Anticholinergic drugs versus non-drug active therapies for non-neurogenic overactive bladder syndrome in adults
Anticholinergic drugs, compared to other drugs for overactive bladder symptoms
Anticholinergic medication for neuroleptic-induced tardive dyskinesia
Anticholinergic medication for non-clozapine neuroleptic-induced hypersalivation in people with schizophrenia
Anticholinergic therapy for acute asthma in children
Anticholinergics (various) for neuroleptic-induced parkinsonism
Anticholinergics for neuroleptic-induced acute akathisia
Anticholinergics for neuroleptic-induced parkinsonism
Anticholinergics for urinary symptoms in multiple sclerosis
Anticholinergics versus placebo for neuroleptic-induced parkinsonism
Anticholinerigic drugs, bladder training or the combination of the two for the management of overactive bladder symptoms
Anticoagulant treatment for subsegmental pulmonary embolism
Anticoagulant treatment for subsegmental pulmonary embolism
Anticoagulants (heparin, low molecular weight heparin and oral anticoagulants) for intermittent claudication
Anticoagulation for cerebral venous sinus thrombosis
Anticoagulation for heart failure in sinus rhythm
Anticoagulation for patients with cancer and central venous catheters
Anticoagulation for the initial treatment of venous thromboembolism in patients with cancer
Anticoagulation for the initial treatment of venous thromboembolism in patients with cancer
Anticoagulation for the long-term treatment of venous thromboembolism in patients with cancer
Anticoagulation therapy versus placebo for pulmonary hypertension
Anticonvulsant therapy for status epilepticus
Anticonvulsants for alcohol dependence
Anticonvulsants for chronic low-back pain
Anticonvulsants for fibromyalgia
Anticonvulsants for preventing seizures in patients with chronic subdural haematoma
Anticonvulsants for tinnitus
Anticonvulsants for tinnitus
Anti-cytomegalovirus treatment in patients with ulcerative colitis
Anti-D administration after spontaneous miscarriage for preventing Rhesus alloimmunisation
Anti-D administration after spontaneous miscarriage for preventing Rhesus alloimmunisation
Anti-D administration in pregnancy for preventing Rhesus alloimmunisation
Antidepressant drugs for older people
Antidepressant medication for children with depression
Antidepressants for agitation and psychosis in dementia
Antidepressants for cocaine dependence and problematic cocaine use
Antidepressants for depressed elderly
Antidepressants for depression during pregnancy
Antidepressants for insomnia
Antidepressants for pain management in rheumatoid arthritis
Antidepressants for painful rheumatological conditions
Antidepressants for patients with tinnitus
Antidepressants for people with both schizophrenia and depression
Antidepressants for people with epilepsy and depression
Antidepressants for polycystic ovary syndrome
Antidepressants for smoking cessation
Antidepressants for the negative symptoms of schizophrenia
Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescents
Antidepressants for the treatment of depression in patients with cancer
Antidepressants for tinnitus
Antidepressants plus benzodiazepines for major depression
Antidepressants versus placebo for depression in primary care
Antidepressants versus placebo for panic disorder in adults
Antidepressants versus placebo for the depressed elderly
Antiemetic medication for prevention and treatment of chemotherapy induced nausea and vomiting in childhood
Anti-epileptic drugs (AEDs) and the risk of teratogenic effects when taken during pregnancy
Antiepileptic drugs as prophylaxis for post-craniotomy seizures
Antiepileptic drugs for neuropathic pain and fibromyalgia
Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews
Antiepileptic drugs for preventing seizures in people with brain tumors
Antiepileptic drugs for the primary and secondary prevention of seizures after intracranial venous thrombosis
Antiepileptic drugs for the primary and secondary prevention of seizures after stroke
Antiepileptic drugs for the primary and secondary prevention of seizures after stroke
Antiepileptic drugs for the primary and secondary prevention of seizures after subarachnoid haemorrhage
Antiepileptic drugs for the primary and secondary prevention of seizures in viral encephalitis
Antiepileptic drugs for the treatment of severe myoclonic epilepsy in infancy
Antiepileptic drugs for treating seizures in adults with brain tumours
Antiepileptic treatments for seizures in multiple sclerosis
Antiepileptics other than gabapentin, pregabalin, topiramate, and valproate for the prophylaxis of episodic migraine in adults
Antifibrinolytic amino acids for upper gastrointestinal bleeding in patients with acute or chronic liver disease
Antifibrinolytic drugs for acute traumatic injury
Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage
Antifibrinolytic therapy to reduce haemoptysis from any cause
Antifibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological disorders
Anti-fibrinolytics (lysine analogues) for the prevention of bleeding in patients with haematological disorders
Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis
Antifungal therapy for newborn infants with invasive fungal infection
Antiglucocorticoid and related treatments for psychosis
Antihistamines for dermatomal itching associated with Lyme disease
Antihypertensive agents for children with chronic kidney disease
Antihypertensive agents for preventing diabetic kidney disease
Antihypertensive drug therapy for mild to moderate hypertension during pregnancy
Anti-hypertensive drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies and clinical trials
Anti-IgE for chronic asthma in adults and children
Anti-IgE therapy for allergic bronchopulmonary aspergillosis in people with cystic fibrosis
Anti-IL-17 monoclonal antibody for induction of remission in Crohn's disease
Anti-inflammatory drugs and analgesics for managing symptoms in people with cystic fibrosis-related arthritis
Anti-inflammatory drugs and risk of Parkinson disease
Anti-inflammatory nasal sprays for the prevention of acute otitis media
Anti-inflammatory treatment for carditis in acute rheumatic fever
Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
Antimetabolites for preventing trabeculectomy failure in people undergoing cataract surgery
Antimetabolites in cataract surgery to prevent failure of a previous trabeculectomy
Antimicrobial dressings for the prevention of catheter-related infections in newborn infants with central venous catheters
Antimicrobial drugs for treating cholera
Antimicrobial lock solutions for preventing catheter-related infections in haemodialysis
Antimicrobial prophylaxis for colorectal surgery
Antimicrobial therapy for chronic bacterial prostatitis
Antimicrobial-impregnated central venous catheters for prevention of catheter-related bloodstream infection in newborn infants
Antimicrobials for treating symptomatic non-typhoidal Salmonella infection
Antimuscarinic drugs for urinary incontinence for frail and institutionalised older people
Antimuscarinic drugs for urinary incontinence in people with dementia and/or Parkinsons disease, and frail older person taking cholinergic agents for dementia
Antimuscarinic medication and inpatient bladder retraining for urinary incontinence
Antioxidant micronutrients for lung disease in cystic fibrosis
Antioxidant multivitamin supplements in malnourished people to slow progression of age-related macular degeneration to more severe stages of the disease
Anti-oxidant pool (vitamins C & E, alpha-lipoic acid and polyunsaturated fats) plus narrow band UVB for repigmentation in vitiligo
Antioxidant supplementation for lung disease in cystic fibrosis
Antioxidant supplements for liver diseases
Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration
Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract
Antioxidants and other pharmacological treatments for Friedreich ataxia
Antioxidants as adjuvants to other drugs in liver diseases
Antioxidants for chronic kidney disease
Antioxidants for female subfertility
Antioxidants for Friedreich ataxia
Antioxidants for idiopathic sudden sensorineural hearing loss
Antiplatelet agents and anticoagulants for hypertension
Antiplatelet agents for chronic kidney disease
Antiplatelet agents for intermittent claudication
Antiplatelet agents including aspirin for the prevention of coronary heart disease (CHD) in diabetes with particular attention to high risk groups (e.g. patients with renal disease and hypertensive disease)
Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm
Antiplatelet and anticoagulant drugs for prevention of restenosis/reocclusion following peripheral endovascular treatment
Antiplatelet and anticoagulation for patients with prosthetic heart valves
Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia
Antiplatelet therapy for subarachnoid haemorrhage.
Antipsychotic drug discontinuation phenomena
Antipsychotic drug treatment for elderly people with late-onset schizophrenia
Antipsychotic drugs for older people with schizophrenia
Antipsychotic drugs for younger people with psychosis
Antipsychotic drugs in first episode of schizophrenia
Antipsychotic medication for childhood-onset schizophrenia
Antipsychotic medication for early episode schizophrenia
Antipsychotic medication for elderly people with schizophrenia
Antipsychotic switching for people with schizophrenia who have neuroleptic-induced weight or metabolic problems
Antipsychotics for acute and chronic pain in adults
Antipsychotics for people with epilepsy and psychosis
Antipyretic measures for treating fever in malaria
Antiresorptive agents for the prevention of fractures after spinal cord injury
Antiretroviral pre-exposure prophylaxis (PrEP) for preventing HIV in high-risk individuals
Antiretroviral therapy for prevention of HIV transmission in HIV-discordant couples
Antispasmodics for labour
Antistreptococcal interventions for guttate and chronic plaque psoriasis
Antithrombin III to decrease blood loss and blood transfusion requirements for liver resection
Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction
Antithyroid drugs plus radioactive iodine for primary hyperthryoidism
Antithyroid drugs plus thyroxine compared with antithyroid drugs alone for primary hyperthyroidism
Antithyroid treatment for subclinical hyperthyroidism
Anti-TNF agents for paediatric psoriasis
Anti-TNF agents for prevention of post-operative recurrence of Crohn's disease
Anti-TNF therapy in inflammatory bowel disease during conception
Anti-TNF-a treatment for pelvic pain associated with endometriosis
Anti-vascular endothelial growth factor (VEGF) drugs for treatment of retinopathy of prematurity
Anti-vascular endothelial growth factor agents for treatment of macular edema secondary to central retinal vein occlusion
Anti-vascular endothelial growth factor for branch retinal vein occlusion
Anti-vascular endothelial growth factor for choroidal neovascularisation in people with pathologic myopia
Anti-vascular endothelial growth factor for macular oedema secondary to central retinal vein occlusion
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration
Anti-vascular endothelial growth factor for neovascular glaucoma
Anti-vascular endothelial growth factor for prevention of postoperative vitreous cavity haemorrhage after vitrectomy for proliferative diabetic retinopathy
Antiviral agents for hepatitis B virus-related cirrhosis
Antiviral interventions for liver transplant patients with recurrent graft infection due to hepatitis C virus
Antiviral medications for preventing cytomegalovirus disease in solid organ transplant recipients
Antiviral prophylactic intervention for chronic hepatitis C virus in patients undergoing liver transplantation
Antiviral prophylaxis for the prevention of chronic hepatitis C virus in patients undergoing liver transplantation
Antiviral therapy for chronic hepatitis C in injecting drug users
Antiviral therapy for chronic hepatitis C in patients coinfected with HBV
Antiviral therapy for chronic hepatitis C in patients coinfected with HIV
Antiviral therapy for chronic hepatitis C in patients who did not respond to treatment with peginterferon plus ribavirin or relapsed following it
Antiviral therapy for chronic hepatitis C in patients with haemophilia
Antiviral therapy for chronic hepatitis C in patients with histologically mild disease
Antiviral therapy for chronic hepatitis C in patients with normal ALT levels
Antiviral therapy for hepatitis C patients without rapid virological response
Antiviral therapy for recurrent liver graft infection with hepatitis C virus
Antiviral therapy in patients with Hepatitis B virus DNA levels of >=20,000 IU/mL and normal ALT levels
Antiviral treatment and other therapeutic interventions for herpes simplex viRCs epithelial keratitis
Antiviral treatment for preventing postherpetic neuralgia
Antivirals alone or combined with immunoglobulin for the prevention of hepatitis B recurrence after liver transplantation
Antivirals for idiopathic sudden sensorineural hearing loss
Any multivitamin or single component antioxidant supplement for age-related macular degeneration to slow or prevent progression
Any versus no fluid resuscitation in acute upper gastrointestinal haemorrhage
Aortic root support in people with Marfan syndrome
APOE-4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a community setting
APOE-4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a primary care setting
APOE-4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a secondary care setting
Appendectomy versus antibiotic treatment for acute appendicitis
Appetite stimulants for people with cystic fibrosis
Approaches to ensure fathers and grandparents help protect or improve the social and emotional wellbeing of vulnerable children aged under 5 years
Appropriate duration and optimal treatment regimen of anti-vascular endothelial growth factor modalities for exudative age-related macular degeneration
Appropriate duration and optimal treatment regimen of anti-vascular endothelial growth factor modalities for neovascular age-related macular degeneration
Appropriateness of US guidelines for early Lyme disease in treating UK and European cases
Aprotinin to decrease blood loss and blood transfusion requirements for liver resection
Aquatic exercise for knee or hip osteoarthritis
Aqueous shunts for glaucoma
Are acetylcholinesterase inhibitors or memantine effective and cost-effective for people with dementia?
Are alternative therapies (massage, acupuncture) beneficial after stroke?
Are alternative treatments helpful for asthma in children?
Are Angiotensin converting enzyme inhibitors (ACE inhibitors) more effective than Angiotensin II receptor antagonists (AIIRA's) in reducing progression of kidney disease and reducing mortality in people with diabetes?
Are antenatal settings an effective and cost- effective location for increasing the uptake of HIV testing for black African male partners of women attending antenatal appointments?
Are anti-anxiety drugs (e.g. benzodiazepines) effective in tinnitus management?
Are anti-depressant drugs (e.g. mirtazepine, amitriptyline, prozac) effective in tinnitus management?
Are anti-inflammatory cortico-steroids (e.g. Prednisolone) effective in tinnitus management?
Are antipsychotic drugs more effective when combined with a mood stabilizer in severe mental illness?
Are antipsychotics bad for my sleep
Are any complementary therapies effective in preventing the severity, frequency and progression of attacks of Ménière's disease?
Are any complementary therapies helpful in preventing/treating glaucoma?
Are any designs of hearing aids like Edulink and others, more or less effective in children and young people with auditory neuropathy and/or auditory processing disorder?
Are any designs of orthoses like Lycra, kinesiotaping, plastic etc., more or less effective to promote functioning and prevent deformity for children and young people with neurodisability?
Are any of the various available alternative therapies effective in the management of tinnitus?
Are any types of physical therapy like Bobath, Neuro-Developmental Therapy, Conductive Education, hydro, constraint, strength-training etc., more or less effective to promote motor functioning in children and young people with neurodisability?
Are bacteria important in causing Hidradenitis suppurativa or triggering flares symptoms?
Are balanced crystalloids superior to a combination of a balanced crystalloid and a gelatin suspended in a balanced solution for the fluid resuscitation of patients with acute hypovolaemic shock?
Are balanced solutions superior to sodium chloride 0.9% for the fluid resuscitation of patients with acute hypovolaemic shock?
Are barrier creams effective in preventing pressure ulcers?
Are behavioural and sensory interventions effective in managing symptoms of Autistic Spectrum Disorder?
Are better results achieved for people with amblyopia if atropine is used as a first-line treatment compared with the results achieved where it is not used as a first-line treatment?
Are botulinum toxin injections effective in reducing enuresis?
Are botulinum toxin injections in patients previously treated with bulking agents for stress urinary incontinence associated with adverse outcomes?
Are breathing exercises helpful for asthma in children?
Are breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises helpful in controlling asthma?
Are Buteyko breathing exercises useful for asthma?
Are calcineurin inhibitors (tacrolimus or pimecrolimus) effective in treating vitiligo?
Are calcineurin inhibitors (tacrolimus or pimecrolimus) more effective if used to treat vitiligo when it first appears, rather than waiting until the disease has spread?
Are calcineurin inhibitors (tacrolimus or pimecrolimus) more effective in treating vitiligo when combined with steroid creams?
Are calcineurin inhibitors applied to the skin safe to use in combination with sun exposure for people with eczema?
Are chest physiotherapy techniques and/or assistive technologies effective to reduce mortality/chest infections/Quality of Life for children and young people with respiratory impairments associated with neurodisability
Are child-centred strategies to improve children's attitudes towards disability effective to improve inclusion and participation within educational, social and community settings?
Are child-focused strategies like one-to-one or group social and skills training effective to improve confidence, self-esteem and promote participation in recreation and leisure activities for children and young people with neurodisability?
Are Chinese herbal medicine Huangqi type formulations effective as treatment for nephrotic syndrome?
Are cochlear implants an effective tinnitus management strategy?
Are coloured glasses known to be of any use in the treatment of colour blindness?
Are community-based upper limb movement re-education programme useful one year after stroke?
Are complementary and alternative (CAM) therapies safe for prostate cancer?
Are complementary and alternative therapies useful following treatment for men living for prostate cancer?
Are complementary therapies effective in the treatment of stress urinary incontinence?
Are complex multi-dose insulin regimes a safe and effective treatment in elderly people with Type 1 and Type 2 diabetes?
Are complimentary therapies effective in slowing, stopping or reversing of disability associated with multiple sclerosis?
Are computer games an effective mode of therapy for children and young people with neurodisability to improve physical and/or social functioning?
Are continuing symptoms of Lyme disease following conventional recommended treatment due to continued infection, or an immune response or other process?
Are counselling/psychological strategies effective to promote the mental health of children and young people with neurodisability?
Are cranberry juice and other alternative or complimentary therapies effective in reducing urinary tract infections?
Are creams and ointments (e.g. steroid creams) more effective when combined with natural sunlight?
Are daycare units cost effective compared with emergency settings for treating patients with an acute painful sickle cell episode?
Are dietary modifications/restrictions effective in managing symptoms of Autistic Spectrum Disorder?
Are disposable catheters more or less accepatable than reusable catheters in terms of effective bladder management, patient experience and urinary tract infections?
Are doctors favouring different drugs for the same condition on the basis of financial incentives?
Are electromechanical assisted gait training and electromechanical and robot-assisted arm training useful and cost effective following a stroke?
Are Enbrel (etanercept) anti-inflammatory injections a safe and effective treatment for severe asthma uncontrolled by oral and inhaled steroids?
Are endurance and strength training effective components of rehabilitation after stroke?
Are environmental interventions clinically and cost effective when compared with standard care for people with psychosis and coexisting substance misuse?
Are exercise and fitness programmes beneficial at improving function and quality of life and avoiding subsequent stroke?
Are exercise-based therapies successful in the treatment of urge urinary incontinence?
Are exposure therapy and/or systematic desensitisation safe and effective treatments for misophonia?
Are GABA receptor antagonists effective in tinnitus management?
Are general practice teams useful in crisis management of people with schizophrenia?
Are genetic factors a good tool to predict prognosis of prostate cancer?
Are glaucoma drops available in a spray formulation?
Are health professionals or the voluntary sector best at helping people achieve independence after stroke?
Are hearing aids an effective management strategy for pulsatile tinnitus?
Are hearing aids an effective tinnitus management strategy for people with a high-frequency hearing loss?
Are hearing aids an effective tinnitus management strategy for people with a mild hearing loss?
Are heat sensors an effective means of assessing pressure damage to the skin when patients enter hospital?
Are heel castings an effective treatment for pressure ulcers on the heel?
Are home sampling and home testing kits a reliable, effective and cost effective method of increasing the uptake of HIV testing among men who have sex with men?
Are home visits helpful after stroke?
Are home-based exercises given to patients with balance disorders effective?
Are homeopathic medicines helpful in asthma?
Are Hopi candles an effective tinnitus management strategy?
Are immunosuppressive treatments effective for focal segmental glomerulosclerosis in adults?
Are injections for wet age-related macular degeneration possible in eyes with scarring due to previous laser treatment?
Are injections in the eye effective and safe for people with age-related macular degeneration?
Are insulin analogues a safe long-term treatment for adults with Type 1 and Type 2 diabetes?
Are insulin analogues a safe long-term treatment for children with Type 1 and Type 2 diabetes?
Are insulin analogues a safe long-term treatment for pregnant women with Type 1 and Type 2 diabetes and their unborn babies?
Are insulin analogues a safe long-term treatment for those with complications and the elderly with Type 1 and Type 2 diabetes?
Are insulin analogues a safe long-term treatment for Type 1 and Type 2 diabetes?
Are Insulin Pens accurate at delivering insulin, even in small doses?
Are interventions for psychosis or substance misuse clinically and cost effective when compared with standard care for people with psychosis and coexisting substance misuse?
Are interventions to improve consistency of approach between agencies like health and education effective to improve behavioural problems in children with Autistic Spectrum Disorder (ASD)?
Are light therapies effective to manage sleep/improve day time functioning for children and young people with neurodisability?
Are medications to treat an underlying headache effective in reducing tinnitus symptoms?
Are moisturisers effective in stopping the spread of vitiligo?
Are mortality rates and complication rates for the human, analogues and animal insulin's different?
Are natural products or dietary supplements effective for the treatment of Hidradenitis suppurativa?
Are natural thermal mineral waters effective in knee osteoarthritis?
Are nerve blocks effective in palliative care?
Are nerve root blocks helpful in terms of diagnostic specificity, and improving pain relief for patients?
Are nonsteroidal anti-inflammatory drugs (NSAIDs) contraindicated in orthopaedic surgery?
Are novel immunotherapy treatments such as banked HLA-matched (human leucocyte antigen) cytotoxic T lymphocytes (CTLs) effective in kidney transplant patients with Post Transplant Lymphoproliferative Disorders?
Are oro-motor treatment strategies like oral motor exercises, sensory stimulation, sensorimotor activities etc., effective to improve eating and drinking or speech for children and young people with neurodisability? Are there identifiable subgroups that benefit more from the strategies?
Are patient-focused education programmes effective in preventing pressure ulcers?
Are PET scans accurate for staging of prostate cancer?
Are phosphodiesterase inhibitors safe in people with diabetes mellitus who have coronary artery disease?
Are postmanoeuvre activity restrictions necessary after canalith repositioning procedure?
Are postural management programmes like using standing frames and sleep systems etc., effective and cost effective to prevent deformity of the hip and/or spine, and improve function in children and young people with neurodisability?
Are prophylactic antibiotics more effective than lifestyle advice for the reduction of urinary tract infections?
Are proven risk reductions in macrovascular disease in diabetes when employed simultaneously, additive, multiplicative or otherwise?
Are psychological interventions less effective in older people with severe mental illness?
Are psychological therapies helpful for asthma compared to drugs?
Are psychosocial interventions clinically and cost effective when compared with standard care for people with psychosis and coexisting substance misuse?
Are public awareness campaigns effective at preventing pressure ulcers?
Are rapid-acting insulin analogues beneficial in children and adolescents?
Are relaxation techniques beneficia after stroke?
Are saunas and swimming good for controlling asthma?
Are secondary prevention drugs effective in preventing subsequent strokes?
Are sensory processing/integration therapeutic programmes effective in improving behaviour and/or increasing play/participation for children and young people with neurodisability?
Are side effects of antipsychotics proportional to their effectiveness?
Are simulators effective tools for the assessment of clinical competence?
Are sleeping tablets an effective management strategy for tinnitus-related insomnia?
Are social activities beneficial for schizophrenia?
Are some treatments better than others depending on which body site is involve?
Are specialist stroke nurses better than non-specialist nurses at improving recovery after stroke?
Are steroid creams more effective if used to treat vitiligo when it first appears, rather than waiting until the disease has spread?
Are steroids better taken by inhaling them or in tablet form for controlling asthma in children?
Are stop smoking interventions that include incentives to quit effective and cost effective for people using secondary care services, including women who are pregnant or have recently given birth?
Are stress management techniques helpful in patients with balance disorders
Are stroke co-ordinators / liason workers beneficial in the management of stroke?
Are stroke groups/clubs helpful at improving the sense of well-being among stroke survivors?
Are supplements beneficial for people with multiple sclerosis and what supplements are most effective to treat multiple sclerosis?
Are surgical operations to close pressure ulcers value for money to the NHS?
Are technologies which alert when an area is subject to high pressure effective at preventing pressure ulcers
Are the adverse effects of antipsychotic drugs worse in the morning?
Are the drugs used to treat maternal asthma harmful to the infant during breastfeeding?
Are the emissions produced by diathermy a health hazard to patients and staff?
Are the eyes of the elderly deceased (eg 75 - 80 years old) of any use for transplant?
Are the most effective pressure relieving mattresses also the most comfortable?
Are the phosphodiesterase inhibitors as effective as other therapeutic options to treat erectile dysfunction?
Are therapeutic doses of low-molecular-weight heparin (LMWH) effective, compared with prophylactic doses of LMWH, in reducing the length of stay in hospital of patients with an acute painful sickle cell episode?
Are there accurate methods of eye testing for prescription glasses for people with thyroid eye disease who may have optic neuropathy, double vision and muscle problems?
Are there advantages of taking a squirt of Ventolin prior to the regular twice daily Flixotide dose?
Are there age related clinical indicators that limit the use of radiotherapy and chemo therapy for prostate cancer?
Are there alternative methods for assessing visual fields that are more acceptable to patients?
Are there alternative treatments apart from lid-cleansing and antibiotics for people with blepharitis and marginal ulcers?
Are there alternative treatments to hormone therapy that have less impact on Quality of Life for men with prostate cancer?
Are there any advantages of combined antihistamine preparations (e.g. Arlevert) for the management of Ménière's disease?
Are there any alternative methods other than laser therapy for diabetic retinopathy treatment?
Are there any alternatives to drugs which help in asthma?
Are there any complementary therapies or supplements that help in asthma?
Are there any dietary choices or supplements that could help stop retinal detachments?
Are there any dietary measures that can prevent prostate cancer or slow its progression?
Are there any effective drug treatments for prostate cancer that would replace the need for surgery and/or radiotherapy?
Are there any effective interventions for the ear pressure symptoms in Ménière's disease?
Are there any effective surgical interventions for asthma?
Are there any effective treatments for a prostate cancer patient with urinary incontinence?
Are there any exercises or activities which could improve refractive error, whether short- or long-sightedness?
Are there any exercises that could help stop retinal detachments?
Are there any eye exercises that can be done to speed the recovery of a muscle palsy resulting in double vision for people with diabetic eye condition?
Are there any foods or eye exercises that could help to delay the onset of reduced vision due to normal ageing of the cornea?
Are there any interventions to help prostate cancer patients who develop psychological effects (such as anxiety, depression) over the course of active surveillance?
Are there any in-utero interventions that could alter the genetic condition of the foetus in a family where there is known albinism?
Are there any lifestyle changes can be taken to prevent age related macular degeneration (AMD)?
Are there any lifestyle changes that can be made to impact the progression of age related macular degeneration (AMD)?
Are there any lifestyle measures that can be taken to prevent cataract?
Are there any long term side effects associated with steroid cream treatments?
Are there any long-term carcinogenic risks associated with treatment with insulin analogues?
Are there any measures that can be taken to prevent pale optic nerve?
Are there any more reliable means of testing for prostate cancer?
Are there any non-drug alternatives to manage my asthma?
Are there any non-intrusive diagnostic tests that will identify aggressive prostate cancer patients whilst not identifying harmless cancers? (Tigers and Pussycats)
Are there any non-intrusive diagnostic tests that will identify aggressive prostate cancers whilst not identifying harmless cancers?
Are there any 'rapid relief' interventions for acute vertigo in Ménière's disease other than vestibular sedatives?
Are there any risks associated with depigmentation in treating vitiligo?
Are there any self-administered, cheap, easy and safe therapies that patients have discovered that help balance problems?
Are there any side effects associated with permanent, or semi-permanent, cosmetic camouflage for the management of vitiligo?
Are there any side effects associated with using calcineurin inhibitors (tacrolimus or pimecrolimus) to treat vitiligo?
Are there any side effects associated with using piperine (black pepper) cream to treat vitiligo?
Are there any side effects associated with using pseudocatalase cream combined with UVB light therapy in treating vitiligo?
Are there any side effects associated with using steroid creams in treating vitiligo?
Are there any side effects associated with using UVA light therapy in treating vitiligo?
Are there any side effects associated with UVB light therapy in treating vitiligo?
Are there any specific techniques that patients can adopt (e.g. certain visual or positional strategies) that can help in an acute attack of Ménière's disease?
Are there any traits in children which could predict glaucoma? - eg sensitivity to bright light.
Are there any treatments for prostate cancer that have minimal effect on urinary continence?
Are there any treatments that can restore vision in someone who is completely blind from retinopathy of prematurity?
Are there any treatments to avoid esophageal stricture in patients with dystrophic epidermolysis bullosa?
Are there any uveitis treatments available that do not cause other ocular problems?
Are there benefits of hospital treatment compared to home care treatment for psychotic episodes?
Are there differences between the mortality and complication rates found in people who use human analogue and animal insulins?
Are there differences in efficacy between the 3 phosphodiesterase inhibitors available in UK?
Are there different types of tinnitus and can they be explained by different mechanisms in the ear or brain?
Are there indicators of the correct time for starting individual treatments for prostate cancer?
Are there lifestyle, environmental, or genetic factors that predispose to macular micro holes?
Are there long term adverse effects of ECT for schizo-affective disorders
Are there long-term consequences for lyme disease if treatment is delayed?
Are there methods to prevent or improve the treatment of macular holes?
Are there safe methods of treating astigmatism other than using spectacles or contact lenses?
Are there suitable long-term pharmacological interventions to be recommended postnatally for women who have been diagnosed with gestational diabetes to prevent the onset of type 2 diabetes?
Are there unintended consequences from encouraging people of South Asian origin to stop using smokeless tobacco (for example, do they experience more dental pain or start smoking more tobacco)?
Are there universally accepted criteria for the diagnosis of Hidradenitis suppurativa?
Are there ways (complementary or conventional) to alleviate the side effects of hormone therapy taken for prostate cancer?
Are there ways of restoring sight loss for people with age related macular degeneration (AMD)?
Are topical tacrolimus and pimecrolimus for atopic eczema safe or can they cause lymphoma or skin cancer?
Are vaginal cones an effective therapy for women with post natal stress urinary incontinence?
Are variations in practice by non-specialist clinicians detrimental to outcomes for treatment of prostate cancer?
Are Vitamin D analogues (calcipotriol and tacalcitol) more effective in treating vitiligo when combined with light therapy?
Are Vitamin D analogues (calcipotriol and tacalcitol) more effective in treating vitiligo when combined with steroid creams?
Are vocational and recreational activities better than impairment-based treatments for someone following a stroke?
Are weighted vaginal cones effective for urinary incontinence?
Arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes
Aripiprazole alone or in combination for acute mania
Aripiprazole for autism spectrum disorders (ASD)
Aripiprazole for neuroleptic induced hyperprolactinaemia
Aripiprazole for people with schizophrenia whose illness has been partially responsive to clozapine
Aripiprazole versus other atypical antipsychotics for schizophrenia
Aripiprazole versus placebo for schizophrenia
Aromatase inhibitors and tamoxifen for breast cancer in women with a family history of breast or ovarian cancer
Aromatase inhibitors for short stature in male children and adolescents
Aromatase inhibitors for subfertile women with polycystic ovary syndrome
Aromatase inhibitors for subfertile women with polycystic ovary syndrome
Aromatase Inhibitors for the adjuvant treatment of breast cancer in postmenopausal women
Aromatase inhibitors for uterine fibroids
Aromatherapy for dementia
Aromatherapy for pain management in labour
Aromatherapy for treatment of postoperative nausea and vomiting
Aromatherapy massage for whiplash neck injury?
Art therapy for people with dementia
Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria
Arteriovenous extracorporeal membrane carbon dioxide removal
Artesunate for Lyme disease
Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria
Artesunate versus quinine for treating severe malaria
Arthroplasties (with or without bone cement) for proximal femoral fractures in adults
Arthroplasty versus fusion in single-level cervical degenerative disc disease
Arthroscopic debridement from knee osteoarthritis
Arthroscopic trochleoplasty for patellar instability
Arthroscopy for temporomandibular disorders
Artichoke leaf extract for treating hypercholesterolaemia
'As required' medication regimens for seriously mentally ill people in hospital
As required versus fixed schedule analgesic administration schedules for treating postoperative pain in children and adults
As thyroid eye disease may develop before thyroid problems themselves are evident, what diagnostic measures may be used to detect thyroid eye disease in the absence of an overactive thyroid?
Asenapine versus typical antipsychotics for schizophrenia
Aspiration and sclerotherapy versus hydrocoelectomy for treating hydrocoeles
Aspiration for treating radial head fractures
Aspiration of middle-ear effusions prior to insertion of ventilation tubes
Aspirin and clopidogrel compared to oral anticoagulant and clopidogrel for people who have had an MI
Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia
Aspirin as adjunctive treatment for giant cell arteritis
Aspirin compared to other triptans and NSAIDS and acute migraine
Aspirin for in vitro fertilisation
Aspirin for vascular dementia
Aspirin versus low molecular weight heparin as thromboprophylaxis in surgical, particularly orthopaedic, patients.
Aspirin with or without an antiemetic for acute migraine headaches in adults
Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease
Assertive community treatment for people with severe mental disorders in the UK
Assertive Outreach Teams (AOT) for schizophrenia and other serious mental disorders in the UK
Assessment of techniques to ascertain correct endotracheal tube placement in neonates
Assessment of the value of neuropathic pain medication for treatment of chronic pelvic pain in women
Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)
Assisted reproductive technology: an overview of Cochrane Reviews
Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve function after hip arthroplasty
Assistive technology for rheumatoid arthritis
Assistive technology, including orthotic devices, for the management of contractures in adult stroke patients
At what age should preventative use of statins be started in those with Type 1 diabetes?
At what point following start of statins and other Coronary Vascular Disease risk-modification is it appropriate to reduce/withhold blood pressure lowering agents?
At what point should people with Hidradenitis suppurativa be referred for specialist care?
Atherectomy for peripheral arterial disease
At-home versus institutional long-term-care for chronic functionally dependent older people
Atomoxetine for schizophrenia
Atropine therapy versus no atropine therapy for the prevention of adverse events in paediatric patients undergoing intubation
Attachment-based family therapy in young people to prevent suicide and suicidal behaviours
Atypical antipsychotics for disruptive behaviour disorders in children and youths
Atypical antipsychotics for psychosis in adolescents
Audio-visual presentation of information for informed consent for participation in clinical trials
Audit and feedback: effects on professional practice and healthcare outcomes
Auditory integration training and other sound therapies for autism spectrum disorders
Auditory-verbal therapy for promoting spoken language development in children with permanent hearing impairments
Augmentation of antipsychotic monotherapy with lithium where a schizophrenic illness has shown only a partial response
Augmentation of antipsychotic monotherapy with sodium valproate where a schizophrenic illness has shown only a partial response
Augmentation of clozapine monotherapy with an appropriate second antipsychotic where a refractory schizophrenic illness has shown only a partial response to clozapine
Augmentative communication devices for adults with autism
Augmenting antipsychotic monotherapy with an antidepressant to treat persistent negative symptoms
Autoinflation for hearing loss associated with otitis media with effusion
Autologous blood and platelet rich plasma injection therapy for lateral elbow pain
Autologous blood donation to decrease blood loss and blood transfusion requirements for liver resection
Autologous fat grafting for breast reconstruction
Autologous hematopoietic stem cell transplantation following high-dose chemotherapy for non-rhabdomyosarcoma soft tissue sarcomas
Autologous platelet-rich plasma for treating chronic wounds
Autologous platelet-rich plasma for treating surgical wounds
Autologous serum eye drops for dry eye
Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children
Automated weaning and spontaneous breathing trial systems versus non-automated weaning strategies for discontinuation time in invasively ventilated postoperative adults
Ayurvedic medicine for schizophrenia
Ayurvedic treatments for diabetes mellitus
Azapirones versus placebo for panic disorder in adults
Azathioprine (low dose) plus PUVA for repigmentation in vitiligo
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease
Azathioprine for psoriasis
Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease
Azathioprine or 6-mercaptopurine for induction of remission in fistulizing Crohn's disease
Azathioprine or 6-mercaptopurine to induce mucosal healing in Crohn's disease
Azathioprine to glucocorticosteroid treatment for patients with intestinal Crohn's disease compared with glucocorticosteroid treatment alone
Azelaic acid for acne
Azithromycin for treating uncomplicated malaria
Azithromycin versus penicillin G benzathine for early syphilis
B12 for pernicious anaemia dosing frequencies based on the patients’ symptoms rather than on number value of serum B12 blood tests
Baby-led compared with scheduled (or mixed) breastfeeding for successful breastfeeding
Bacille Calmette-Gu?rin (BCG) for long term effects against tuberculosis (TB)
Baclofen for alcohol withdrawal
Balloon dilatation of the eustachian tube
Balloon kyphoplasty for vertebral compression fractures
Balneotherapy for osteoarthritis
Balneotherapy for psoriasis
Balneotherapy for psoriatic arthritis
Balneotherapy for rheumatoid arthritis
Balsalazide versus mesalazine for maintenance of remission in ulcerative colitis
Balsalazide versus sulfasalazine for induction and maintenance of remission in ulcerative colitis
Banding ligation versus beta-blockers for primary prevention in oesophageal varices in adults
Banding ligation versus beta-blockers for primary prophylaxis of oesophageal variceal bleeding in children
Barbiturates for acute traumatic brain injury
Bare-metal stenting compared with balloon angioplasty in patients with acute myocardial infarction
Bariatric surgery for non-alcoholic steatohepatitis in obese patients
Bariatric surgery for obesity
Bariatric surgery in the treatment of severely obese adolescents?
Barriers and facilitators to the implementation of doctor-nurse substitution strategies in primary care: qualitative evidence synthesis
Barriers and facilitators to the implementation of lay health worker programmes to improve access to maternal and child health: qualitative evidence synthesis
Bath emollients for atopic eczema
Beclometasone for chronic obstructive pulmonary disease
Bed rest in hospital for suspected impaired fetal growth
Bee venom acupuncture for rheumatoid arthritis
Behavioral interventions for improving condom use for dual protection
Behavioral interventions for improving contraceptive use among women living with HIV
Behavioral interventions for improving contraceptive use among women living with HIV
Behavioral interventions for improving dual-method contraceptive use
Behavioral interventions for urinanry incontinence in acute care settings
Behavioral interventions to promote condom use among women living with HIV
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in high-income countries
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in low- and middle-income countries
Behavioural and cognitive interventions with or without other treatments for the management of faecal incontinence in children
Behavioural and cognitive-behavioural group-based parenting programmes for early-onset conduct problems in children aged 3 to 12 years
Behavioural counselling to reduce incidences of skin cancer
Behavioural interventions as adjuncts to pharmacotherapy for smoking cessation
Behavioural interventions for attention deficit-hyperactivity disorder (ADHD)
Behavioural interventions for promoting respiratory protection use in workers
Behavioural interventions for reducing weight gain in schizophrenia
Behavioural therapies versus other psychological therapies for depression
Behavioural treatments for non-epileptic attack disorder
Belatacept for kidney transplant recipients
Belimumab for systemic lupus erythematosus
Bendamustine for patients with indolent B cell lymphoid malignancies including chronic lymphocytic leukaemia
Benefit, tolerability, and safety of drugs used to treat urinary incontinenece in frail older people
Benefits and harms of biliary stenting via ERCP for pancreatico-biliary stricture confirmed or suspected to be malignant, prior to surgery?
Benzodiazapines for catatonia in persons with schizophrenia and other serious mental illnesses.
Benzodiazepines and antipsychotic drugs for urgent urgent sedation/control of acute behavioural disturbance
Benzodiazepines for generalised anxiety disorder (GAD)
Benzodiazepines for neuroleptic-induced tardive dyskinesia
Benzodiazepines for psychosis-induced aggression or agitation
Benzodiazepines for schizophrenia
Benzodiazepines in non-alcohol related delirium in hospitalised patients
Benzodiazepines versus placebo for panic disorder in adults
Best psychological treatment for effective treatment of functional non-epileptic attacks
Beta blockers for peripheral arterial disease
Beta lactam antibiotic monotherapy versus beta lactam-aminoglycoside antibiotic combination therapy for sepsis
Beta radiation for glaucoma surgery
Beta2-adrenoceptor agonists for dysmenorrhoea
Beta2-agonists for exercise-induced asthma
Beta2-receptor polymorphism for improving long-term beta-agonist efficacy in asthma
Beta2-receptor polymorphism for improving long-term beta-agonist efficacy in asthma
Beta-blockers for congestive heart failure in children
Beta-blockers for hypertension
Beta-blockers for preventing aortic dissection in Marfan's syndrome
Beta-blockers for preventing stroke recurrence
Beta-blockers for slowing/halting the progress of aortic root dilation
Beta-blockers for slowing/halting the progress of aortic root dilation in people with Marfans syndrome
Betahistine for Ménière's disease or syndrome
Betahistine for symptoms of vertigo
Beta-lactam versus beta-lactam-aminoglycoside combination therapy in cancer patients with neutropenia
Betamimetics for inhibiting preterm labour
Betamimetics for suspected impaired fetal growth
Bevacizumab (safety and efficacy) in the treatment of age-related macular degeneration
Bevacizumab for peole who have previously been treated with a taxane for metastatic breast cancer
Bezafibrate for primary biliary cirrhosis
Bicarbonate versus lactate solutions for acute peritoneal dialysis
Bicyclol for chronic hepatitis B
Bicyclol for chronic hepatitis C
Bile acid sequestrants among people with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection
Bile acids for non-alcoholic fatty liver disease and/or steatohepatitis
Biochemical tests of placental function for assessment in pregnancy
Biocompatible dialysis fluids for peritoneal dialysis
Biofeedback and/or sphincter exercises for the treatment of faecal incontinence in adults
Biofeedback for Ménière's disease.
Biofeedback for stress urinary incontinence
Biofeedback for tension-type headache
Biofeedback for treatment of chronic idiopathic constipation in adults
Bioidentical hormones for women with hot flushes
Biological treatments for psoriatic arthritis
Biologics for juvenile idiopathic arthritis
Biologics for rheumatoid arthritis
Biologics, colchicine, corticosteroids, immunosuppressants and interferon-alpha for Neuro-Behcet's Syndrome
Biomarkers as point-of-care tests to guide prescription of antibiotics in patients with acute respiratory infections in primary care
Biomarkers for assessing disease activity in inflammatory bowel disease
Biomarkers in stable coronary artery disease for prognosis
Biomedical risk assessment as an aid for smoking cessation
Biopsy versus resection for high grade glioma
Biopsy versus resection for the management of low-grade gliomas
BIS monitoring versus clinical assessment for sedation in mechanically ventilated adult patients in the intensive care unit and its impact on clinical outcomes and resource utilization
Bismuth subsalicylate for lymphocytic colitis or collagenous colitis
Bispectral index for improving anaesthetic delivery and postoperative recovery
Bisphosphonate therapy for children and adolescents with secondary osteoporosis
Bisphosphonate therapy for osteogenesis imperfecta
Bisphosphonates and atrial fibrillation
Bisphosphonates and other bone agents for breast cancer
Bisphosphonates for osteoarthritis
Bisphosphonates for osteoporosis
Bisphosphonates for osteoporosis in people with cystic fibrosis
Bisphosphonates for osteoporosis in primary biliary cirrhosis
Bisphosphonates for osteoporotic fractures
Bisphosphonates for preventing and treating osteoporosis in men
Bisphosphonates in multiple myeloma: a network meta-analysis
Black cohosh (Cimicifuga spp.) for menopausal symptoms
Black pepper extract or piperine for repigmentation in vitiligo
Bladder retraining protocols for treating urinary incontinence
Bladder training in the management of overactive bladder symptoms
Bladder training in the management of urinary incontinence
Blood CEA levels for detecting recurrent colorectal cancer
Blood pressure lowering efficacy of alpha blockers for primary hypertension
Blood pressure lowering efficacy of loop diuretics for primary hypertension
Blood pressure lowering efficacy of nonselective beta-blockers for primary hypertension
Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension
Blood pressure targets for hypertension in people with diabetes mellitus
Blood pressure targets for the treatment of patients with hypertension and cardiovascular disease
Blood pressure-lowering efficacy of monotherapy with thiazide diuretics for primary hypertension
Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease
Blood transfusions for anaemia in patients with advanced cancer
Body positioning for spontaneously breathing preterm infants with apnoea
Bone anchored hearing aids for patients with congenital unilateral aural atresia
Bone augmentation procedures in implant dentistry
Bone marrow versus peripheral blood allogeneic haematopoietic stem cell transplantation for haematological malignancies in adults
Bone marrow versus peripheral blood allogeneic hematopoietic stem cell transplantation for haematological malignancies
Bortezomib for the treatment of multiple myeloma
Bosutinib in patients with Philadelphia-chromosome-positive chronic myeloid leukaemia previously treated with 1 or more tyrosine kinase inhibitors
Botulinium toxin A in the treatment of idiopathic detrusor overactivity
Botulinum toxin A and percutaneous sacral nerve stimulation for the treatment of Overactive Bladder after failed conservative (including drug) management?
Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy
Botulinum toxin compared with (a) usual care, (b) antimuscarinics and (c) augmentation cystoplasty in people with primary cerebral conditions with lower urinary tract dysfunction?
Botulinum toxin compared with antimuscarinics in people with primary cerebral conditions with lower urinary tract dysfunction?
Botulinum toxin compared with augmentation cystoplasty in people with primary cerebral conditions with lower urinary tract dysfunction
Botulinum toxin for masseter hypertrophy
Botulinum toxin for myofascial pain syndromes in adults
Botulinum toxin for myofascial pain syndromes in adults
Botulinum toxin for shoulder pain
Botulinum toxin for spasmodic dysphonia
Botulinum toxin for subacute/chronic neck pain
Botulinum toxin for the treatment of strabismus
Botulinum toxin for upper oesophageal sphincter dysfunction in neurological swallowing disorders
Botulinum toxin for upper oesophageal sphincter dysfunction in neurological swallowing disorders
Botulinum toxin injections for adults with overactive bladder symptoms
Botulinum toxin injections for adults with overactive bladder syndrome
Botulinum toxin type A in the treatment of lower limb spasticity in cerebral palsy
BRAHMS copeptin assay in combination with cardiac troponin testing against sequential cardiac troponin testing for ruling out myocardial infarction
Breast cancer in female survivors of childhood, adolescent or young adult cancer after radiotherapy involving the chest for their primary malignancy
Breast feeding and development of childhood wheeze
Breastfeeding for oral health in preschool children
Breastfeeding for procedural pain in infants beyond the neonatal period
Breastfeeding or breast milk for procedural pain in neonates
Breathing exercises for adults with asthma
Breathing exercises for children with asthma
Breathing exercises for chronic obstructive pulmonary disease
Breathing exercises for dysfunctional breathing/hyperventilation syndrome in adults
Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children
Brief co-incubation of sperm and oocytes for in vitro fertilization techniques
Brief interventions (including brief advice) delivered by community members compared to brief interventions delivered by health professionals vs smokeless tobacco
Brief interventions for heavy alcohol users admitted to general hospital wards
Brief school-based interventions and behavioural outcomes for substance-using adolescents
Bright light therapy for patients at risk of delirium
Broad band UVB monotherapy for repigmentation in vitiligo
Broad-spectrum light sources for acne
Bromocriptine for type 2 diabetes mellitus
Bromperidol decanoate (depot) for schizophrenia
Bronchial thermoplasty for moderate or severe persistent asthma in adults
Bronchodilators for bronchiolitis
Bronchodilators for the prevention and treatment of chronic lung disease in preterm infants
Bronchoscopy-guided antimicrobial therapy for cystic fibrosis
Buccal or sublingual misoprostol for cervical ripening and induction of labour
Budesonide for lymphocytic colitis
Budesonide for maintenance of remission in Crohn's disease
Buflomedil for intermittent claudication
Built environment interventions for increasing physical activity in adults and children
Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome
Buprenorphine for treating cancer pain
Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
Bupropion for depression
Bupropion versus other antidepressive agents for depression
Bypass for primary percutaneous intervention or thrombolysis at the nearest hospital for patients suffering ST-elevation myocardial infarction
Cabergoline for preventing ovarian hyperstimulation syndrome
Caesarean delivery for the second twin
Caesarean section for non-medical reasons at term
Caesarean section versus vaginal delivery for preterm birth in singletons
Caesarean section versus vaginal delivery for preventing mother to infant hepatitis C virus transmission
Caffeine as an analgesic adjuvant for acute pain in adults
Caffeine reduction for urinanry incontinence in frail elderly people
Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients
Calcineurin inhibitor minimisation versus continuation of calcineurin inhibitor treatment for liver transplant recipients
Calcipotriol plus PUVA or UVB for psoriasis
Calcitonin for metastatic bone pain
Calcitonin testing for detection of medullary thyroid cancer in patients with thyroid nodules
Calcitriol and alfacalcidol for preventing fractures and falls
Calcium antagonists as an add-on therapy for drug-resistant epilepsy
Calcium antagonists for Duchenne muscular dystrophy
Calcium channel blockers as medical expulsive therapy for ureteric stones
Calcium channel blockers for inhibiting preterm labour and birth
Calcium channel blockers for people with chronic kidney disease requiring dialysis
Calcium channel blockers for primary Raynaud's phenomenon
Calcium channel blockers for pulmonary arterial hypertension
Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Calcium supplementation commencing before or early in pregnancy, or food fortification with calcium, for preventing hypertensive disorders of pregnancy
Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Calcium supplementation for hip fracture
Calcium supplementation for prevention of primary hypertension
Can a goal setting approach help recovery after stroke?
Can a befriending scheme reduce loneliness and improve confidence and wellbeing in isolated older people?
Can a better Hidradenitis suppurativa severity scoring system be devised that is practical to use?
Can a change in anti-epileptic drug timing affect seizure control?
Can a cure be developed for vitreous syneresis / degenerative vitreous / eye floaters?
Can a daily routine help stroke prevention?
Can a functioning prosthetic eye be developed to replace an eye damaged by injury?
Can a gene therapy be developed for Ushers?
Can a gene therapy be developed to treat Stargardts?
Can a gene therapy treatment be developed for keratoconus?
Can a large anti-epileptic drug dosage lead to an increase in seizure frequency in some individuals?
Can a neuro-vision technology package improve functional ability and quality of life after stroke?
Can a non-invasive therapy be developed for wet age related macular degeneration (AMD)?
Can a non-pharmaceutical treatment be the primary one for psychosis?
Can a one stop treatment for glaucoma be developed?
Can a retinal vein occlusion be predicted and prevented?
Can a stem cell therapy be developed for Ushers?
Can a stem cell treatment be developed for choroideremia?
Can a stem cell treatment be developed for Fuchs?
Can a stem cell treatment be developed for optic atrophy?
Can a stem cell treatment for age related macular degeneration (AMD) be developed?
Can a susceptibility to mitomycin-C test be developed for use before trabeculectomy?
Can a treatment / cure effective for all be developed for wet age related macular degeneration (AMD)?
Can a treatment / cure for macular degeneration be developed?
Can a treatment be developed for albinism?
Can a treatment be developed for choroideremia?
Can a treatment be developed to improve vision for people with albinism?
Can a treatment to slow down progression or reverse sight loss in inherited retinal diseases be developed?
Can a treatment to stop dry age related macular degeneration (AMD) progressing and/or developing into the wet form be devised?
Can acute deterioration of asthma be prevented? i.e. appropriate treatment 48 hours earlier; role of “At Risk” registers
Can admission of people to hospital with suspected stroke prevent or reduce subsequent stroke?
Can Adult Education improve stroke aquired literacy/numeracy problems following a stroke?
Can alternative therapies reduce central post stroke pain?
Can alternative treatments for retinoblastoma other than radiotherapy be developed?
Can an accurate prognosis of multiple sclerosis be achieved as a predictor of relapses, disability, symptoms and life style changes and response to treatment?
Can an alternative or new treatment be developed that will treat the sight loss caused by giant cell arteritis?
Can an artificial cornea be made for transplantation for people with keratoconus?
Can an assessment for people using mobility scooters help reduce accidents (to themselves/running others over)?
Can an effective long lasting treatment for diabetic macular oedema, both ischaemic and non-ischaemic, be developed?
Can an objective measure to assess the severity of eye floaters (e.g. size, opacity, motility, quantity, position relative to the retina, etc) be developed?
Can an objective screening method be used nationally in children so that early diagnosis is obtained and treatment can be started?
Can an optic nerve damaged by injury be regenerated?
Can angiotensin-converting enzyme (ACE) inhibitors and ACE angiotensin II receptor blockers (ARB) be used in combination to treat early diabetic nephropathy?
Can antibiotics be stopped after 6 or 12 weeks, and therapy continued with a non-antibiotic-based regimen such as benzoyl peroxide or a topical retinoid?
Can anti-epileptic drugs interfere with blood results?
Can antiviral therapy induce remission of proteinuria in paediatric patients?
Can any complementary therapies help prevent the progression of glaucoma?
Can any dietary measures prevent glaucoma?
Can any dietary measures prevent the progression of glaucoma?
Can any dietary supplements prevent the development of glaucoma?
Can any dietary supplements prevent the progression of glaucoma?
Can any lifestyle changes prevent the progression of glaucoma?
Can any lifestyle choices (eg exercise, reduction of stress) prevent glaucoma?
Can any treatment avoid hair loss in patients with dystrophic epidermolysis bullosa?
Can anything be done in childhood to prevent the development of refractive error?
Can anything be done to prevent a retinal vein occlusion from occuring in either eye?
Can anything be done to reduce pseudo-exfoliation in glaucoma?
Can applying steroids to my skin make eczema worse?
Can arts-based interventions and art therapy improve recovery after stroke?
Can asthma medication at bedtime keep my child awake?
Can auditory 'brain training' improve tinnitus?
Can auditory feedback improve walking, independence and quality of life after stroke?
Can avoiding chocolate influence acne severity?
Can babies experience anti-epileptic drug withdrawal?
Can better interventions be developed that are effective in treating vitreous opacities / eye floaters?
Can better treatments for glaucoma in children be developed?
Can bladder training help continence problems following a stroke?
Can Botox be used to help patients who have glaucoma and migraine?
Can botulinum toxin injections be effective in treating nocturia?
Can buddy systems (volunteers) improve quality of life after stroke?
Can bulking agents for stress urinary incontinence worsen urge incontinence?
Can cataract surgery be improved?
Can central serous retinopathy be prevented?
Can children newly diagnosed with type 1 diabetes be stabilised at home or do all need hospital admission?
Can clinics for Alzheimer's and dementia go around sheltered housing (mobile units) for early diagnosis?
Can cognitive behavioural therapy (CBT) help attainment of goals after stroke?
Can cognitive behavioural therapy (CBT) help recovery of speech following stroke?
Can cognitive 'brain training' improve tinnitus?
Can combined Anti-vascular endothelial growth factor (Anti-VEGF)/steroids/photodynamic therapy (PDT) therapies increase chances of longer treatment-free intervals and reduction of number of overall injections for people with age related macular degeneration (AMD)?
Can complementary therapies affect the progress of myopia?
Can complementary therapies affect the progression of keratoconus?
Can complementary therapies impact the progression of age related macular degeneration (AMD)?
Can complementary therapies impact the progression of Birdshot?
Can complementary therapies influence the impact of thyroid eye disease(TED)?
Can corneal infections be prevented in high-risk individuals such as contact lens wearers?
Can counselling help couples address relationship difficulties after stroke?
Can counselling prevent depression following stroke?
Can diabetic retinopathy and medicines for its treatment accelerate macular degeneration from dry to wet?
Can diet affect the progression of Leber's hereditary optic neuropathy (LHON)?
Can diet influence clinical outcomes in dystrophic epidermolysis bullosa patients?
Can diet or lifestyle changes prevent thyroid eye disease (TED)?
Can diet or lifestyle changes prevent uveitis from developing?
Can dietary and lifestyle choices prevent vitreous opacities/eye floaters?
Can dietary factors, nutritional supplements, complementary therapies or lifestyle changes prevent or slow the progression of Age related macular degeneration?
Can dietary measures affect the progress of keratoconus?
Can dietary measures affect the progress of myopia?
Can dietary measures help prevent diabetic retinopathy?
Can dietary measures impact the progression of Birdshot?
Can dietary measures influence the impact of thyroid eye disease (TED)?
Can dietary measures prevent age related macular degeneration (AMD)?
Can dietary measures prevent Birdshot?
Can dietary measures prevent dry eye?
Can dietary measures slow the progress of retinitis pigmentosa?
Can dietary measures slow the progression of diabetic retinopathy?
Can dietary measures, dietary supplements or complementary therapies slow down the progression of cataracts?
Can dietary measures, nutritional supplements or complementary therapies prevent cataract?
Can dietary supplements help slow the progression of age related macular degeneration (AMD)?
Can dietary supplements impact the progression of Birdshot?
Can dietary supplements prevent the onset of retinitis pigmentosa symptoms?
Can donor eyes or their components be used to address age related macular degeneration (AMD)?
Can drusen be prevented?
Can early detection methods be developed for ocular and orbital inflammatory disease?
Can early psychological support increasing confidence and awareness of choices following a stroke?
Can early sound enrichment as an intervention after hearing trauma prevent tinnitus from developing?
Can EBV monitoring, such as measuring viral loads and responses such as cytotoxic T-cell counts, be effective in patients with Post Transplant Lymphoproliferative Disorders?
Can effective treatment of irritable bowel syndrome reduce lower urinary tract symptoms associated with prostate disease?
Can electrical stimulation improve arm function following a stroke?
Can electrofacial stimulation improve facial muscle weakness after stroke?
Can emotional support improve ability for self-help following a stroke?
Can environmental or lifestyle factors trigger Birdshot?
Can epilepsy treatment cause Dupuytren's?
Can exercise have an effect on biomarkers associated with multiple sclerosis?
Can exercise improve accommodation in presbyopic people?
Can exercise therapy improve outcomes for prostate cancer?
Can eye transplants be developed for people with retinitis pigmentosa?
Can gene therapy be developed for retinitis pigmentosa?
Can gene therapy help regenerate damaged optic nerves?
Can gene-based targeted therapies for ocular cancers be developed?
Can genetic testing for prostate cancer reduce my risk of being wrongly diagnosed, and over- or under-treated?
Can guidance or training for general practitioners on appropriate pathways of care improve the management of patients with urinary incontinence?
Can holistic therapies such as acupuncture, meditation, hypnotherapy help in preventing Birdshot?
Can house dust mites worsen atopic eczema?
Can I have a nebuliser at home?
Can I make any changes in my diet to help with my tinnitus?
Can I rely on the PSA test alone to monitor prostate cancer recurrence after radical treatment?
Can imagery improve outcomes after stroke?
Can implanted devices be effective in reducing the tinnitus sound?
Can information technology (IT) improve information given about preventative lifestyles?
Can interventions to manage pressure change help my tinnitus?
Can iris cysts be removed safely?
Can IV aminophylline be used preventatively for people with difficult to treat asthma?
Can keeping the eyes partially light adapted at night slow or halt sight loss caused by diabetic eye disease?
Can keratoconus be treated with lasers?
Can laser eye surgery trigger progress of age related macular degeneration (AMD)?
Can laser therapy alleviate tinnitus?
Can leg splints improve balance and walking after stroke?
Can lifestyle changes influence the impact of (thyroid eye disease) TED?
Can lifestyle changes, supplements, herbal remedies or complementary therapies improve the quality of life for people with vitreous opacities / eye floaters?
Can lifestyle factors affect the progression of retinitis pigmentosa?
Can lifestyle factors trigger the onset of retinitis pigmentosa?
Can lifestyle measures affect the progression of proliferative diabetic retinopathy?
Can long term use of steroids for asthma cause problems with your liver?
Can Lutein help prevent age related macular degeneration (AMD)?
Can Lutein slow the progression of age related macular degeneration (AMD)?
Can Lyme disease be transmitted via other means?
Can Macushield help prevent age related macular degeneration (AMD)?
Can magnetic therapy alleviate tinnitus?
Can massage therapies (e.g. head and neck massage) effectively alleviate tinnitus symptoms?
Can medical canabis help lower intraocular pressure and treat glaucoma?
Can medicine in a form of tablet prevent progression of diabetic retinopathy?
Can 'mind puzzles' help delay the onset of dementias?
Can modified diet influence acne severity?
Can multiple sclerosis be prevented in relatives and family members of people with multiple sclerosis?
Can music or art therapy help people with aphasia following stroke?
Can music therapy help recovery after stroke?
Can my asthmatic child participate in sport at school?
Can needle biopsy of the prostate cause cancer to spread?
Can new non-invasive treatments be developed to slow down the progression of diabetic retinopathy?
Can new therapies such as gene or stem cell treatments be developed for corneal diseases?
Can non-drug treatments improve insomnia after stroke?
Can non-pharmaceutical treatment be used as a primary intervention in psychosis?
Can non-surgical therapy be developed for Fuchs' corneal dystrophy?
Can nurses assess swallowing in patients after stroke?
Can nurses decide whether and when to insert a nasogastric (feeding) tube for people following a stroke?
Can nursing treatments prevent depression following a stroke?
Can nutritional supplements affect the progression of keratoconus?
Can nutritional supplements affect the progression of retinitis pigmentosa?
Can nutritional supplements have an adverse impact on eye health?
Can nutritional supplements influence the impact of thyroid eye disease (TED)?
Can nutritional supplements prevent age related macular degeneration (AMD)?
Can ophthalmic diagnostic equipment provide a more accurate diagnosis for glaucoma progression, than images that are compared manually at appointments?
Can overdose/misuse of antipsychotic drugs cause psychotic symptoms?
Can overuse of salbutamol whilst taking becotide make one's asthma worse?
Can patients have a nebuliser at home to treat their asthma?
Can PCO or secondary cataract be prevented?
Can pelvic floor muscle training be effective in preventing incontinence associated with an overactive bladder?
Can people with schizophrenia be diagnosed earlier by GPs, and can the management of first episode psychosis be carried out in general practice?
Can peri-operative interventions prevent post-operative cognitive impairment following anaesthesia?
Can physiotherapy help in tinnitus management?
Can physiotherapy improve mood disorders after stroke?
Can playing an instrument help improve communication problems following stroke?
Can pre-hospital clinicians perform Femoral Nerve Block safely and effectively in those with proximal femoral fracture?
Can pre-hospital clinicians perform urinary catheterisation safely and effectively in patients with proximal femoral fracture?
Can preoperative Cardiopulmonary Exercise Testing (CPX) testing be cost effective in selecting patients who do not require protected high level care after surgery?
Can preoperative testing identify 'difficult' airways amenable to specific interventions?
Can presenting the same sound as your tinnitus provide an effective tinnitus management strategy?
Can prostate cancer spread after transurethral resection of the prostate (TURP) procedure?
Can psychological support help increase participation in physical activity after stroke?
Can radioactive iodine treatment for Graves's disease adversely affect existing thyroid eye disease with or without taking steroids?
Can regional anaesthesia be performed safely in patients on clopidogrel and other antiplatelet agents?
Can reliable methods of self monitoring eye pressure be developed and improve outcomes?
Can retinal detachment be prevented after cataract surgery?
Can retinal detachment be prevented?
Can screening programmes reduce the risk of subsequent stroke?
Can self-monitoring of blood pressure help stroke prevention?
Can severe ocular surface disease in children, such as blepharokeratoconjunctivitis and vernal keratoconjunctivitis be managed better?
Can smoking cannabis can decrease the symptoms of hyperactive thyroid/Graves eye disease affecting the eyes?
Can some individuals benefit from lower antiepileptic drug dosages than the therapeutic range suggested?
Can squamous cell cancer of the skin in an ageing UK population be reduced using currently available cream treatment for actinic keratoses?
Can Stargardts disease be diagnosed in infants or young children?
Can stem cells be used to improve cleft palate repair (both primary and secondary)?
Can stem cells be used to regrow an eye or part of an eye?
Can supported communication training for carers of someoen following a stroke help prevent relationship breakdown?
Can supraglottic airway devices replace intubation in the majority of patients?
Can surgical procedures on the balance system (semi-circular canals) alleviate pulsatile tinnitus?
Can surgical techniques be improved to save sight for eyes damaged by injury?
Can talking books help people relearn social skills after stroke?
Can targeted patient education and empowerment reduce the incidence of pressure ulcer development?
Can telemedicine be used to raise the use of blood glucose monitoring in adolescent and young people with diabetes, in particular?
Can the development of age related macular degeneration (AMD) be predicted?
Can the diagnosis of inherited retinal diseases be refined so that individuals can be given a clearer idea about their specific condition and how it is likely to progress?
Can the early stages of optic neuropathy be detected?
Can the incidence of cataract in glaucoma patients be lessened?
Can the long term effects of radiotherapy for retinoblastoma be prevented?
Can the onset of dementia be prevented or delayed by dietary or nutritional factors?
Can the outcomes of corneal transplantation be improved?
Can the prostatectomy procedure cause prostate cancer cells to spread?
Can the return of cloudy or blurred vision after cataract surgery known as posterior capsule opacity (PCO) or secondary cataract be prevented?
Can the severity of ocular and orbital inflammatory disease in an individual be predicted?
Can the treatment of amblyopia be improved to produce better short and long term outcomes than are possible with current treatments?
Can the way of measuring psoriasis and psoriatic arthritis in adults be improved?
Can therapeutic positioning improving outcome after stroke?
Can too high a dose of antipsychotic cause psychotic symptoms?
Can trained volunteers and carers help improve communication after stroke?
Can transcranial magnetic stimulation (TMS) help recovery after stroke?
Can transcranial magnetic stimulation help people with aphasia following stroke?
Can treatment of insomnia related to tinnitus reduce tinnitus distress independently?
Can treatments arising from social and environmental psychology improve recovery after stroke?
Can treatments be developed for visual field and ocular motility manifestations following stroke?
Can treatments for congenital cataract be improved?
Can treatments for keratoconus be developed that don't require a corneal graft?
Can treatments that I put on my skin make my eczema worse?
Can treatments to save eye sight from microbial keratitis be improved?
Can upper limb splints improve arm function and prevent complications after stroke?
Can vision be corrected in later life for people with amblyopia?
Can vision be improved in people with amblyopia by asking them to do eye exercises?
Can vision be restored for people whose retina was detached many years ago?
Can vision loss due to optic nerve diseases such as giant cell arteritis, optic neuritis and optic atrophy, be restored?
Can vitamin D prevent multiple sclerosis?
Can volunteers help the process of information provision following a stroke?
Can we accurately test for amblyopia in children under 2 years old?
Can we achieve full binocular vision for children with lazy eye if we treat the condition or does treatment only every partially restore vision?
Can we control the levels of thyroid stimulating hormone when the thyroid gland has been destroyed?
Can we create an implant that can replace the dead retinal ganglion cells for people with Leber's hereditary optic neuropathy (LHON)?
Can we cure astigmatism?
Can we detect age-related macular degeneration early enough for it to be treated before visual loss is experienced?
Can we detect diabetic retinopathy before identifying diabetes?
Can we determine whether refractive keratoplasty can be used to treat childhood anisometropic amblyopia rather than standard therapy?
Can we determine which eyes are likely to benefit from occlusion therapy administered in patients with different types of amblyopia? (x10)
Can we determine which inherited eye diseases are likely to be treatable with gene therapy?
Can we develop a cure for Alstrom Syndrome?
Can we develop a cure for Birdshot?
Can we develop a cure for Blepharitis?
Can we develop a cure for Graves eye Disease?
Can we develop a cure for keratoconus?
Can we develop a cure for Leber's hereditary optic neuropathy (LHON)?
Can we develop a cure for retinitis pigmentosa?
Can we develop a cure for thyroid eye disease (TED)?
Can we develop a drop treatment for retinitis pigmentosa?
Can we develop a drug that is safe to use to reverse the effects and cure amblyopia instead of using occlusion therapy or atropine?
Can we develop a gene therapy treatment for glaucoma?
Can we develop a gene therapy treatment for Leber's congenital amaurosis (LCA) that can be used in the first couple of years of life?
Can we develop a gene therapy treatment for Leber's hereditary optic neuropathy (LHON)?
Can we develop a non-surgical treatment for blepharitis?
Can we develop a stem cell treatment for glaucoma?
Can we develop a stem cell treatment for keractoconus?
Can we develop a stem cell treatment for Leber's congenital amaurosis (LCA)?
Can we develop a stem cell treatment for Leber's hereditary optic neuropathy (LHON)?
Can we develop a stem cell treatment for optic neuritis?
Can we develop a stem cell treatment for optic neuropathy?
Can we develop a stem cell treatment for retinitis pigmentosa?
Can we develop a test to give all patients with retinitis pigmentosa a definitive genetic diagnosis?
Can we develop a treatment for achromatopsia? Can gene therapy cure those with Achromatopsia, particularly those people with no cone photoreceptor cells rather than damaged or defective cone cells? Is there evidence to suggest that gene therapy or stem cell therapy could be successful interventions for human beings with Achromatopsia/Blue Cone Monochromatism/Rod Monochromatism?
Can we develop a treatment for central serous retinopathy?
Can we develop a treatment for children with myopia rather than using glasses to correct vision?
Can we develop a treatment for pale optic nerve?
Can we develop a treatment for persistent hyperplastic primary vitreous (PHPV)?
Can we develop a treatment for Stargardts?
Can we develop a treatment or cure for dry eye?
Can we develop a way of permanently treating coloboma?
Can we develop an alternative treatment for severe dry eye condition combined with high blood pressure and severe headaches without affecting quality of everyday life by administering medicines every half hour of the day?
Can we develop artificial corneas to treat corneal disease?
Can we develop better treatments for cerebral visual impairment in children?
Can we develop better ways of measuring visual fields?
Can we develop less aggressive treatments for Punctate Outer Retinal Necrosis (PORN)
Can we develop new therapies for astigmatism?
Can we develop new treatments for branch retinal vein occlusion?
Can we develop new treatments for thyroid eye disease without harmful side effects?
Can we develop stem cell treatments for corneal disease?
Can we develop treatments for optic neuropathy?
Can we develop treatments for presbyopia that remove the need for glasses?
Can we develop treatments for uveitis that don't involve steroids?
Can we devlop a cure for adult vitelliform macular dystrophy?
Can we eliminate the side effects of eye drops?
Can we find a cure or treatment for Behcets?
Can we find a treatment for Birdshot that doesn't have side effects?
Can we help restore vision in a lazy eye by encouraging the brain to make the necessary connections?
Can we manage acne without resorting to antibiotics and help to curb the rise of antibiotic resistance?
Can we predict whether children of carriers with Leber's Hereditary Optic Neuropathy (LHON) will lose sight?
Can we prevent myopia? Refractive Error and Ocular Motility Ranked 10.
Can we prevent presbyopia?
Can we prevent sight loss connected to shingles in over 65's?
Can we recover binocular function in adults with squint and amblyopia following treatment?
Can we reduce the rate of diabetic retinopathy by better screening?
Can we repair or regenerate the optic nerve?
Can we self diagnose and self monitor low pressure glaucoma?
Can we slow down the progress of retinitis pigmentosa?
Can we slow down the progression of keratoconus?
Can we treat amblyopia more effectively by administering oral medication with or without occlusion therapy compared to just using occlusion therapy?
Can we treat or cure colour blindness?
Can we use intra-ocular lens implantation in children?
Can we use novel drugs or therapies in the treatment of aniridia?
Canaloplasty for primary open-angle glaucoma
Cancer genetic risk assessment for individuals at risk of familial breast cancer
Canine scent detection methods for early diagnosis of human cancers
Cannabinoid type 1 receptor antagonists for smoking cessation
Cannabinoids for epilepsy
Cannabinoids for epilepsy
Cannabinoids for Tourette's Syndrome
Capecitabine for ER-positive versus ER-negative breast cancer
Capnography versus standard monitoring for emergency department procedural sedation and analgesia
Capsaicin for allergic rhinitis in adults
Capsaicin for non-allergic rhinitis
Carbamazepine for chronic neuropathic pain and fibromyalgia in adults
Carbamazepine for schizophrenia
Carbamazepine versus valproate monotherapy for epilepsy
Carbetocin for preventing postpartum haemorrhage
Carbetocin for preventing postpartum haemorrhage
Carbohydrate or fat-restricted diets for obesity
Carbohydrates for improving the cognitive performance of independent-living older adults with normal cognition or mild cognitive impairment
Carbon dioxide detection for diagnosis of inadvertent respiratory tract placement of enterogastric tubes in children
Carbon dioxide detection for testing nasogastric tube placement in adults
Cardiac rehabilitation for people with heart disease: an overview of Cochrane systematic reviews
Cardiac resynchronisation therapy (CRT) in patients with atrial fibrillation compared with those with sinus rhythm
Cardiac resynchronisation therapy (CRT) versus optimal medical therapy in chronic heart failure patients with symptoms refractory to optimal medical therapy
Cardiac resynchronisation therapy with with implantable defibrilator (CRT-D) versus implantable cardioverter defibrilator (ICD) to reduce all-cause mortality in chronic heart failure patients
Cardiac resynchronization therapy for dilated cardiomyopathy
Cardiac testing for coronary artery disease in potential kidney transplant recipients
Cardiopulmonary interventions to decrease blood loss and blood transfusion requirements for liver resection
CardioQ-ODM in patients in the critical care environment
Cardiotocography versus intermittent auscultation of fetal heart on admission to labour ward for assessment of fetal wellbeing
Cardiovascular safety of phosphodiesterase inhibitors for treating erectile dysfunction in elderly men
Care delivery and self management strategies to improve outcomes for people with epilepsy
Care delivery and self-management strategies for children with epilepsy
Caregiver-mediated exercises for improving outcomes after stroke
Caries-preventive effect of glass ionomer and resin-based fissure sealants on permanent teeth
Carnitine for fatigue in multiple sclerosis
Carnitine supplementation for inborn errors of metabolism
Carnitine supplementation for preterm infants with recurrent apnoea
Carotid endarterectomy or carotid artery stenting to prevent stroke
Castor oil, bath and/or enema for cervical priming and induction of labour
Catheter ablation for paroxysmal and persistent atrial fibrillation
catheter ablation procedures in south-western europe
Catheter impregnation, coating or bonding for reducing central venous catheter related infections in adults
Catheter policies for management of long term voiding problems in adults with neurogenic bladder disorders
CBT for generalised anxiety disorder in older people compared to working age adults
Celecoxib for osteoarthritis
Celiac plexus block for pancreatic cancer pain in adults
Cemented, cementless or hybrid fixation options in total knee arthroplasty for osteoarthritis and other non-traumatic diseases
Central venous access sites for the prevention of venous thrombosis, stenosis and infection
Central venous catheter (CVC) removal for adult patients with candidaemia
Centralisation of services for gynaecological cancer
Centre-based day care for children under five in high-income countries
Centre-based early education interventions for improving school readiness
Cephalic version by moxibustion for breech presentation
Cephalic version by postural management for breech presentation
Cerebral near-infrared spectroscopy (NIRS) for perioperative monitoring of brain oxygenation in children and adults
Cerebrolysin for vascular dementia
Cerebrospinal fluid drainage for thoracic and thoracoabdominal aortic aneurysm surgery
Certolizumab pegol (CDP870) for rheumatoid arthritis in adults
Certolizumab pegol for Crohn's disease
Cervical assessment by ultrasound for preventing preterm delivery
Cervical cap versus diaphragm for contraception
Cervical pessary for preventing preterm birth
Cervical ripening before first trimester surgical evacuation for non-viable pregnancy
Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy
Cervico-thoracic or lumbar sympathectomy for neuropathic pain and complex regional pain syndrome
Cesarean delivery for the prevention of anal incontinence in average risk pregnancies
Cetuximab in combination with radiotherapy compared with chemoradiotherapy in patients with head and neck cancer
Cetuximab in combination with radiotherapy compared with radiotherapy alone in patients with head and neck cancer
Chamomile and ginkgo biloba for Generalised anxiety disorder
Chelation for autism spectrum disorder (ASD)
Chemical pleurodesis versus surgical intervention for persistent and recurrent pneumothoraces in cystic fibrosis
Chemoembolisation combined with liver resection for neuroendocrine tumours in patients with resectable liver metastases
Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma
Chemoradiation versus hyperthermia versus chemoradiation plus hyperthermia for locally advanced rectal cancer
Chemoradiotherapy for pancreatic carcinoma in patients with no disease progression following 3-4 months of induction chemotherapy
Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer
Chemotherapy alone versus chemotherapy plus radiotherapy for early stage Hodgkin lymphoma
Chemotherapy and surgery versus surgery alone in non-small cell lung cancer
Chemotherapy and/or radiotherapy in combination with surgery for ovarian carcinosarcoma
Chemotherapy for advanced, recurrent or metastatic endometrial carcinoma
Chemotherapy for brain metastases from small cell lung cancer
Chemotherapy for malignant germ cell ovarian cancer in adult patients with early stage, advanced and recurrent disease
Chemotherapy for metastatic and recurrent cervical cancer
Chemotherapy for metastatic carcinoma of the esophagus and gastro-esophageal junction
Chemotherapy for newly diagnosed inoperable brain metastases from non-small cell lung cancer
Chemotherapy for non-small cell lung cancer in the elderly population
Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia
Chemotherapy for thymic carcinoma and advanced thymoma in adults
Chemotherapy given before or after the radiotherapy in locally advanced nasopharyngeal carcinoma
Chemotherapy in the treatment of metastatic cutaneous, uveal and mucosal Melanoma
Chemotherapy versus best supportive care for extensive small cell lung cancer
Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer
Chemotherapy versus surgery with or without adjuvant chemotherapy and radiotherapy for localised primary gastric diffuse large B-cell lymphoma
Chemotherapy wafers for high grade glioma
Chemotherapy with cetuximab versus chemotherapy alone for chemotherapy-naive advanced non-small cell lung cancer
Chemotherapy, radiotherapy, chemoradiotherapy and combination therapy in localised and locally advanced pancreatic cancer
Chest compression alone versus chest compression plus artificial ventilation for out-of-hospital cardiac arrest
Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis
Chest physiotherapy for pneumonia in adults
Chest physiotherapy for pneumonia in children
Chest radiographs for acute lower respiratory tract infections
Chinese and Indian herbal medications for repigmentation in vitiligo
Chinese Herbal Medicine (CHM) in the treatment of women with endometriosis
Chinese Herbal Medicine (CHM) in the treatment of women with primary dysmenorrhoea
Chinese herbal medicine for advanced pancreatic cancer
Chinese herbal medicine for atopic eczema
Chinese herbal medicine for diabetic peripheral neuropathy
Chinese herbal medicine for endometriosis
Chinese herbal medicine for subfertile women with polycystic ovarian syndrome
Chinese herbal medicine for treating recurrent urinary tract infections in women
Chinese herbal medicines combined with other routine treatment for hyperthyroidism
Chinese herbal medicines for adverse events of transarterial chemoembolization in patients with primary liver cancer
Chinese herbal medicines for benign thyroid nodules in adults
Chinese herbal medicines for hypercholesterolemia
Chinese herbal medicines for hypertriglyceridaemia
Chinese herbal medicines for induction of remission in advanced or late gastric cancer
Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose and the delay of diabetes onset
Chinese herbal medicines for skin and soft tissue infections
Chinese herbal medicines for threatened miscarriage
Chinese herbal medicines for treating osteoporosis
Chinese herbal medicines for treating skin and soft-tissue infections
Chinese herbal medicines for unexplained recurrent miscarriage
Chinese herbs combined with Western medicine for severe acute respiratory syndrome (SARS)
Chinese medicinal herbs for acute bronchitis
Chinese medicinal herbs for alleviating chemotherapy-induced short term side effects in breast cancer patients
Chinese medicinal herbs for cholelithiasis
Chinese medicinal herbs for influenza
Chinese medicinal herbs for mumps
Chinese medicinal herbs for sore throat
Chinese zengse pill for repigmentation in vitiligo
Chiropractic medicine for Ménière's disease
CHIVA method for the treatment of chronic venous insufficiency
Chlorambucil for patients with primary biliary cirrhosis
Chlorhexidine gluconate dressings applied to chlorhexidine gluconate prepped skin, to prevent catheter-related bloodstream infections
Chlorhexidine versus topical fluoride treatment for the prevention and management of dental caries in children and adolescents
Chlorpromazine versus atypical antipsychotic drugs for schizophrenia
Cholesterol-reducing agents for aneurysmal subarachnoid haemorrhage
Cholestyramine for lymphocytic colitis or collagenous colitis
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease
Cholinesterase inhibitors for mild cognitive impairment
Chorioretinal venous anastomosis for central retinal vein occlusion
Chromium picolinate supplementation for overweight or obese adults
Chromium picolinate supplementation for overweight or obese people
Chronic heart failure (CHF) self-management for patients with severe physical and mental co-morbidities
Ciclesonide for chronic asthma in adults and children
Ciclesonide versus other inhaled corticosteroids for chronic asthma in children
Ciclosporin for eczema
Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease
Cinnamon for diabetes mellitus
Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small cell lung cancer
Citalopram versus other anti-depressive agents for depression
Citicoline (CDP-choline) for traumatic brain injury
Citrate salts for preventing and treating kidney stones
Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology
Clinical and cost effectiveness of chemical sympathectomy in comparison with other methods of pain control for managing critical limb ischaemic pain
clinical and cost effectiveness of intrapartum antibiotic prophylaxis targeting group B streptococcus and guided by routine antenatal screening?
Clinical and cost effectiveness of selective stent placement compared with angioplasty plus primary stent placement for treating people with critical limb ischaemia caused by disease of the infra-geniculate arteries
Clinical and cost effectiveness of supervised exercise programmes compared with unsupervised exercise for treating people with intermittent claudication
Clinical and cost effectiveness of using GP practice lists to identify people at high risk of fracture, leading to formal risk assessment and possible treatment
Clinical and cost-effectiveness of depot and similar preparations of both conventional and atypical antipsychotics for schizophrenia
Clinical- and cost-effectiveness of mid-urethral tape procedures in the first-line treatment of stress urinary incontinence.
Clinical and cost-effectiveness of monitoring the physical health of people with schizophrenia
Clinical and cost-effectiveness of pelvic floor muscle training in the first-line treatment of stress urinary incontinence
Clinical and economic benefits of cryotherapy compared to standard therapies for the primary treatment of localised prostate cancer
Clinical assessment to screen for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
Clinical course of action when a patient undergoing treatment for Lyme disease experiences a second tick bite
Clinical effectiveness, cost effectiveness and safety of DPP-4 inhibitors, compared with current UK practice or other newer agents, for the long-term management of blood glucose control in people with type 2 diabetes
Clinical effectiveness, cost effectiveness and safety of GLP-1 mimetics (with or without insulin), compared with standard UK practice or other newer agents, for the long-term management of blood glucose control in people with type 2 diabetes
Clinical efficacy and acceptability of combined antipsychotics (including clozapine) for schizophrenia when monotherapy has proved unsatisfactory
Clinical heart failure in children, adolescents and young adults treated with anthracyclines and/or irradiation involving the heart region
Clinical hypnosis for chronic pain in adults
Clinical pathways for primary care: effects on professional practice, patient outcomes, and costs
Clinical service organisation for heart failure
Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community-acquired pneumonia
Clinical, cost and occupational effectiveness of Supported Employment in the UK for schizophrenia
Clinical, economic, quality of life, self-esteem and occupational effectiveness of supported employment for people with schizophrenia
Clinical, social and economic outcomes, including quality of life and the methods and effects of risk monitoring, of treatment by acute day hospitals, assertive outreach teams, in-patient units, and crisis resolution and home treatment teams
Clinically-indicated replacement versus routine replacement of peripheral venous catheters
Clobazam versus other add-on treatments in the management of refractory epilepsy
Clofibrate in combination with phototherapy for unconjugated neonatal hyperbilirubinaemia
Clomiphene citrate in combination with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilization
Clonazepam for neuropathic pain and fibromyalgia in adults
Clonidine premedication for postoperative analgesia in children
Closed reduction methods for acute anterior shoulder dislocation
Closed suction surgical wound drainage after hip fracture surgery
Closure versus medical therapy for preventing recurrent stroke in patients with patent foramen ovale and a history of cryptogenic stroke or transient ischemic attack
Closure versus non–closure of the peritoneum at caesarean section
Closure versus non-closure of the peritoneum at caesarean section: short- and long-term outcomes
Clotiapine for schizophrenia
Clotiapine for schizophrenia
Clozapine against other atypicals for treatment-resistant schizophrenia
Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia.
Clozapine for psychotic disorders in adults with intellectual disabilities
Clozapine to reduce hostility, violence and suicide for people with schizophrenia
Coal tar plus phototherapy (including Goeckerman regime) for psoriasis
Co-bedding in neonatal nursery for promoting growth and neurodevelopment in stable preterm twins
Coblation versus other surgical procedures for tonsillectomy
Coenzyme Q10 for heart failure
Coenzyme Q10 for Parkinson's disease
Co-enzyme Q10 supplementation for the primary prevention of cardiovascular disease
Co-formulated abacavir-lamivudine-zidovudine for initial treatment of HIV infection and AIDS
Cognitive behaviour therapy (brief versus standard duration) for schizophrenia
Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia
Cognitive behaviour therapy versus specific pharmacological treatments for schizophrenia
Cognitive behaviour therapy versus standard care for schizophrenia
Cognitive behavioural therapies for fibromyalgia
Cognitive behavioural therapies versus other psychological therapies for depression
Cognitive behavioural therapies versus treatment as usual for depression
Cognitive behavioural therapy (brief versus standard duration) for schizophrenia
Cognitive behavioural therapy (CBT) based trauma reprocessing intervention on PTSD symptoms in people with psychosis and schizophrenia
Cognitive Behavioural Therapy (CBT) for people with chronic headache disorders to improve headache outcomes and quality of life
Cognitive Behavioural Therapy (CBT) for schizophrenia
Cognitive Behavioural Therapy and guided bibliotherapy compared with a waiting-list control for panic disorder
Cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment resistant depression in primary care: a randomised controlled trial
Cognitive behavioural therapy for anxiety disorders in children and adolescents
Cognitive Behavioural Therapy for borderline personality disorder
Cognitive behavioural therapy for men who physically abuse their female partner
Cognitive behavioural therapy for migrainous vertigo
Cognitive behavioural therapy for the treatment of moderate and severe anxiety disorders in adults with autism
Cognitive Behavioural Therapy in the first episode of schizophrenia and those at risk of relapse
Cognitive reframing for carers of people with dementia
Cognitive rehabilitation (for domains other than memory and learning) in multiple sclerosis
Cognitive rehabilitation for attention deficits following stroke
Cognitive rehabilitation for executive dysfunction in adults with stroke or other adult non-progressive acquired brain damage
Cognitive rehabilitation for spatial neglect following stroke
Cognitive rehabilitation in patients with aquired brain injury
Cognitive stimulation and acetylcholinesterase inhibitors for Alzheimer’s disease over six months
Cognitive stimulation or acetylcholinesterase inhibitors for Alzheimer’s disease over six months
Cognitive stimulation to improve cognitive functioning in people with dementia
Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia
Cognitive training for attention deficit-hyperactivity disorder (ADHD)
Cognitive-behavioural interventions for attention deficit hyperactivity disorder (ADHD) in adults
Cognitive-behavioural interventions for children who have been sexually abused
Cognitive-behavioural therapy (CBT) interventions for young people aged 10 to 18 who sexually offend
Cognitive-behavioural treatment for subacute and chronic neck pain
Colchicine for acute gout
Colchicine for pericarditis
Colchicine for prevention of cardiovascular events
Colchicine for primary biliary cirrhosis
Cold-water immersion (cryotherapy) for preventing and treating muscle soreness after exercise
Colesevelam for type 2 diabetes mellitus
Collaboration between local health and local government agencies for health improvement
Collaborative care approaches for people with severe mental illness
Collaborative care for depression and anxiety problems
Collaborative care for depression and anxiety problems in primary care
Colloid solutions for fluid resuscitation
Colloids versus crystalloids for fluid resuscitation in critically ill patients
Colony-stimulating factors for prevention and treatment of infectious complications in patients with acute myelogenous leukemia
Colorectal stents for the management of malignant colonic obstructions
Combinant therapy for seizure control in neonatal seizures
Combination chemotherapy for primary treatment of high-risk gestational trophoblastic tumour
Combination contraceptives: effects on weight
Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children
Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children
Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children
Combination inhaled corticosteroids and long-acting beta2-agonists for children and adults with bronchiectasis
Combination inhaled steroid and long-acting beta2-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease
Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease
Combination inhalers as single treatment for asthma compared to standard therapy
Combination injectable contraceptives for contraception
Combination methods for HIV prevention in men who have sex with men (MSM)
Combination of tocolytic agents for inhibiting preterm labour
Combination pharmacological and weight-loss therapy for non-alcoholic fatty liver disease
Combination pharmacotherapy for the treatment of fibromyalgia
Combination pharmacotherapy for the treatment of neuropathic pain in adults
Combination therapies in hepatitis B patients with decompensated cirrhosis
Combination therapy for pain management in inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis)
Combination therapy of heparin and graded compression stockings versus heparin alone for prevention of fatal pulmonary embolism in colorectal surgery
Combination therapy with newer nucleoside analogues for chronic hepatitis B
Combination versus sequential single agent chemotherapy for metastatic breast cancer
Combinations of interventions for dealing with domestic violence and abuse in the short, medium and long term?
Combinations of treatments for osteoarthritis
Combined and alternating paracetamol and ibuprofen therapy for febrile children
Combined corticosteroid and long-acting beta2-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease
Combined corticosteroid and long-acting beta2-agonist in one inhaler versus long-acting beta2-agonists for chronic obstructive pulmonary disease
Combined corticosteroid and long-acting beta2-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
Combined corticosteroid and longacting bronchodilator in one inhaler for chronic asthma
Combined corticosteroid and longacting bronchodilator in one inhaler for chronic asthma
Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccine for primary prevention of hepatitis B
Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB)
Combined inhaled anticholinergics and short-acting beta2-agonists for initial treatment of acute asthma in children
Combined levothyroxine (L-T4) + liothyronine (L-T3) therapy for patients diagnosed with hypothyroidism.
Combined oestrogen and progesterone for preventing miscarriage
Combined oral contraceptive pills for treatment of acne
Combined oral contraceptives: the risk of myocardial infarction and ischemic stroke
Combined oral contraceptives: venous thrombosis
Combined pharmacology and psychotherapy for older adults with generalised anxiety disorder
Combined pharmacotherapy and behavioural interventions for smoking cessation
Combined psychological and pharmacological interventions compared with either intervention alone in the treatment of adults with social anxiety disorder
Combined spinal-epidural versus epidural analgesia in labour
Combined split-thickness/suction grafts for repigmentation in vitiligo
Combined treatment with macrolides and hydroxychloquine for Lyme disease
Combined vestibular rehabilitation and cognitive behavioural treatment of chronic dizziness
Combining antipsychotics to treat schizophrenia that has proved to be poorly responsive to adequate trials of antipsychotic monotherapy
Combining presciption antidepressant drugs and psychological treatments for depression
Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Commercial weight loss products and services for obese and overweight adults
Commercially available pelvic binder/splint compared to a circumferential sheet for immobilising/stabilising a pelvic trauma in the prehospital environment
Communication aids for patients with central nervous system tumours
Communication skills training for healthcare professionals working with people who have cancer
Communication skills training for mental health professionals working with people with severe mental illness
Community based interventions for reducing dengue incidence
Community coalition-driven interventions to reduce health disparities among racial and ethnic minority populations
Community interventions for preventing smoking in young people
Community mental health teams (CMHTs) for people with severe mental illnesses and disordered personality
Community Mental Health Teams trained to deliver specialist treatment, compared to specialist teams (e.g. Crisis Resolution, Home Treatment, and Early Intervention), for serious mental illness
Community mobilization and empowerment interventions for preventing HIV in low and middle income countries
Community pharmacy interventions for health promotion: effects on professional practice and health outcomes
Community wide interventions for increasing physical activity
Community-based self-management programs for improving participation in life activities in older adults with chronic conditions
Community-based, population level interventions for promoting child oral health
Community-directed interventions for informing and/or educating about early childhood vaccination
Community-wide approaches to managing obesity
Comparable effectiveness of therapies for unresectable recurrent and in-transit extremity melanoma.
Comparative educational outcomes of different drug treatments for childhood attention deficit-hyperactivity disorder (ADHD)
Comparative effectiveness of different combined oral contraceptive pills for acne in women
Comparative efficacy of biological therapies for patients with psoriasis who fail to respond to conventional systemic treatments
Compared to a plaster on the buttock, is the therapeutic effect of an oestrogen plaster against menopausal symptoms on the stomach significantly higher?
Comparison of alternative therapies and progestagens and anti-progestagens for pain associated with endometriosis
Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants
Comparison of chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for patients with early unfavourable or advanced stage Hodgkin lymphoma
Comparison of different models of preconception counselling to reduce adverse pregnancy outcome in women with epilepsy
Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation
Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding
Comparison of initial antibiotic regimens for Lyme disease where both options are less than one month
Comparison of luminal agents for use in conjuction with nitroimidazoles for eradication of Entamoeba histolytica from the intestine and for decreasing relapse
Comparison of self administered survey questionnaire responses collected using mobile apps versus other methods
Comparison of short and long term treatment regimens for amoebic colitis
Comparison of speech and language therapy techniques for speech problems in Parkinson's disease
Comparison of the efficacy of different anti-TNF agents in Crohn's disease
Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women
Comparisons of outcomes from different packages of care for treatment of chronic pelvic pain in women
Complement inhibitors for age-related macular degeneration
Complementary and alternative medicine in the treatment of sinusitis
Complementary and alternative medicine treatments for atopic eczema
Complementary and alternative therapies for acne
Complementary and alternative therapies for post-caesarean pain
Complementary and miscellaneous interventions for nocturnal enuresis in children
Complementary medicine, self-help and lifestyle interventions for obsessive compulsive disorder
Complementary therapies for chronic plaque psoriasis
Complementary therapies for prostate cancer: is there any evidence of their efficacy/effectiveness?
Complementary therapies for schizophrenia
Complementary therapies for schizophrenia
Complementary therapies in the management of childhood nocturnal enuresis
Complete cytoreduction for advanced epithelial ovarian cancer
Complex behavioural interventions for nocturnal enuresis in children
Complex interventions for preventing diabetic foot ulceration
Compliance therapy for schizophrenia
Comprehensive assessment versus a brief assessment comprehensive assessment conducted by mental health professional versus a brief assessment by conducted by a paraprofessional?
Comprehensive exercise interventions for multiple sclerosis
Comprehensive geriatric assessment for older adults admitted to hospital
Comprehensive paediatric assessments for children in out of home care
Compression for preventing recurrence of venous ulcers
Compression for venous leg ulcers
Compression stockings for the initial treatment of varicose veins in patients without venous ulceration
Compulsory community and involuntary outpatient treatment for people with severe mental disorders
Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death
Computed tomography (CT) compared to magnetic resonance imaging (MRI) in hip fracture
Computed tomography versus magnetic resonance imaging versus bone scintigraphy for clinically suspected scaphoid fractures in patients with negative plain radiographs
Computer-assisted surgery for knee ligament reconstruction
Computer-assisted versus oral-and-written dietary history taking for diabetes mellitus
Computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of type 2 diabetes mellitus
Computer-assisted versus oral-and-written history taking for the management of cardiovascular disease
Computer-based diabetes self-management interventions for adults with type 2 diabetes mellitus
Computer-generated reminders delivered on paper to healthcare professionals; effects on professional practice and health care outcomes
Computerised tomography (CT) versus magnetic resonance imaging (MRI) for staging and for predicting optimal cytoreduction in women with ovarian cancer
Computerized advice on drug dosage to improve prescribing practice
Concomitant adalimumab and other immunosuppressants for induction and maintenance of remission in Crohn's disease
Concomitant corticosteroids and adalimumab for induction and maintenance of remission in Crohn's disease
Concurrent chemoradiotherapy (alternative fractionation schedules) versus sequential chemoradiotherapy
Concurrent chemoradiotherapy with weekly versus three-weekly cisplatin in locally advanced head and neck squamous cell carcinoma
Conjugate Haemophilus influenzae type b vaccines for sickle cell disease
Conjugate vaccines for preventing Haemophilus influenzae type b infections in children under 5 years of age
Conservative compared to operative treatment for hip fractures in adults
Conservative interventions for treating Achilles tendon ruptures
Conservative interventions for treating diaphyseal fractures of the forearm bones in children
Conservative interventions for treating exercise-related musculotendinous, ligamentous and osseous groin pain
Conservative interventions for treating hyperextension injuries of the proximal interphalangeal joints of the fingers
Conservative interventions for treating middle third clavicle fractures in adolescents and adults
Conservative interventions for treating scaphoid fractures in adults
Conservative interventions for treating work-related complaints of the arm, neck or shoulder in adults
Conservative management following closed reduction of traumatic anterior dislocation of the shoulder
Conservative management for postprostatectomy urinary incontinence
Conservative management of acoustic neuroma
Conservative management of nocturia in adults
Conservative management such as pelvic floor muscle training for postprostatectomy urinary incontinence
Conservative prevention and management of pelvic organ prolapse in women
Conservative treatment for middle third clavicle fractures in adolescents and adults
Conservative treatment for osteoarthritis of the ankle
Conservative treatment for whiplash
Conservative versus interventional management for primary spontaneous pneumothorax in adults
Conservative versus liberal fluid therapy for initial severe sepsis and septic shock
Constraint-induced movement therapy of the upper limb in children with hemiplegic cerebral palsy
Consultation letters for medically unexplained physical symptoms in primary care
Consumer guidelines for chronic disease management
Consumer-providers of care for adult clients of statutory mental health services
Contact tracing in household contacts and homeless people for latent infection and active tuberculosis disease
Containment strategies for people with serious mental illness
Continence care in the frail elderly.
Continence education programmes
Contingency management for substance use disorders
Continuation and maintenance treatments for depression in older people
Continuation and maintenance treatments for depressive disorder in older adults
Continuous and interrupted suturing techniques for repair of episiotomy or second-degree tears
Continuous cardiotocography (CTG) as a form of electronic fetal monitoring (EFM) for fetal assessment during labour
Continuous erythropoiesis receptor activator (CERA) for the anaemia of chronic kidney disease
Continuous glucose monitoring systems for type 1 diabetes mellitus
Continuous heparin infusion to prevent thrombosis and catheter occlusion in neonates with peripherally placed percutaneous central venous catheters
Continuous interscalene brachial plexus block versus parenteral analgesia for postoperative pain relief after major shoulder surgery
Continuous negative extrathoracic pressure or continuous positive airway pressure compared to conventional ventilation for acute hypoxaemic respiratory failure in children
Continuous or extended cycle vs. cyclic use of combined hormonal contraceptives for contraception
Continuous passive motion following total knee arthroplasty in people with arthritis
Continuous passive motion for preventing venous thromboembolism after total knee arthroplasty
Continuous passive motion for preventing venous thromboembolism after total knee arthroplasty
Continuous positive airway pressure (CPAP) for acute bronchiolitis in children
Continuous renal replacement therapy (CRRT) for rhabdomyolysis
Continuous subcutaneous insulin infusion compared with intensive insulin injections
Continuous support for women during childbirth
Continuous support for women during childbirth.
Continuous versus bolus intragastric tube feeding for preterm and low birth weight infants with gastro-oesophageal reflux disease
Continuous versus bolus intragastric tube feeding for preterm and low birth weight infants with gastro-oesophageal reflux disease
Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections
Continuous versus intermittent physiological monitoring for acute stroke
Continuous versus intermittent renal replacement therapy for patients with acute kidney injury
Continuous versus interrupted skin sutures for non-obstetric surgery
Continuous versus interrupted skin sutures for non-obstetric surgery
Contraception interventions for women seeking abortion
Contraceptive services for young people from diverse faith and cultural communities
Contralateral bone anchored hearing aids in acquired unilateral sensorineural hearing loss in adults
Contralateral prophylactic mastectomy for women with breast cancer
Control of humidity and excessive heat in the home for preventing or reducing the severity of atopic eczema
Conventional occlusion versus pharmacologic penalization for amblyopia
Cooling for cerebral protection during brain surgery
Cooling for newborns with hypoxic ischaemic encephalopathy
Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients
Corneal collagen cross-linking for treating keratoconus
Correctors (specific therapies for class II CFTR mutations) for cystic fibrosis
Cortical and deep brain stimulation for functional recovery and reducing complications after stroke
Corticosteroid implants for chronic non-infectious uveitis
Corticosteroid injection for de Quervain's tenosynovitis
Corticosteroid injections compared to splinting or surgery for trigger finger in adults
Corticosteroids as adjunctive therapy in the treatment of influenza
Corticosteroids as standalone or add-on treatment for sore throat
Corticosteroids for acute bacterial meningitis
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy
Corticosteroids for dengue infection
Corticosteroids for Guillain-Barr? syndrome
Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy
Corticosteroids for ocular toxoplasmosis
Corticosteroids for parasitic eosinophilic meningitis
Corticosteroids for pneumonia
Corticosteroids for preventing postherpetic neuralgia
Corticosteroids for the common cold
Corticosteroids for the management of cancer-related pain in adults
Corticosteroids for the treatment of chronic asthma in adults and children aged 12 years and over
Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis)
Corticosteroids for the treatment of Kawasaki disease in children
Corticosteroids for treating hypotension in preterm infants
Corticosteroids for treating nerve damage in leprosy
Corticosteroids for treating optic neuritis
Corticosteroids for viral myocarditis
Corticosteroids used in addition to antiviral drugs in patients with Ramsay Hunt syndrome
Cost effectiveness of interventions to prevent or manage obesity in children and adults in the UK?
Cost effectiveness of lisdexamfetamine in children and adolescents with attention deficit-hyperactivity disorder (ADHD)
Cost effectiveness of proton pump inhibitors versus placebo for stress ulcer prophylaxis in critically ill patients
Cost-effectiveness analysis of mesalamine for prevention of post-operative recurrence of Crohn's disease
Cost-effectiveness of clobazam versus newer anti-epileptic drugs
Cost-effectiveness of the newest anti-epileptic drugs as first line therapy
Costs and benefits of preconception counselling of women with epilepsy to healthcare organisations
Costs and benefits of preconception counselling to women with epilepsy
Cot-nursing versus incubator care for preterm infants
Cotrimoxazole for the prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection
Could any supplements or dietary changes help reduce the damage caused by retinopathy of prematurity?
Could artificial lenses be fitted to help treat age-related macular degeneration?
Could biomarkers be used to track disease progression in thyroid eye disease?
Could electronic/computerised equipment help standardise the interpretation of diagnostic tests such as the Digital Rectal Exam for men with prostate cancer?
Could investment in psychological support for people suffering from corneal erosion syndrome be beneficial?
Could in-vivo imaging of the pathological processes in the cornea be improved to the level of in-vivo imaging available for retinal disease?
Could low birthweight be a factor in the development of Hidradenitis suppurativa?
Could some sort of implants into the eye help to alleviate dry eyes?
Could the accurate testing of refractive error be made less dependent on a subjective response?
Could the telescopic implants used for macular degeneration work for people with birdshot?
Could the use of standard systems (e.g. nomograms) to assess prostate cancer risk and response to treatment improve outcomes?
Could vision be improved by the use of glasses (? with stronger lenses) for people with age-related macular degeneration?
Covered versus uncovered metal palliative biliary stents for obstructing pancreatic carcinoma
Cranberries for preventing urinary tract infections
Creatine and creatine analogues in hypertension and cardiovascular disease
Creatine for amyotrophic lateral sclerosis/motor neuron disease
Creatine for Parkinson's disease
Creatine for treating muscle disorders
Creatine for women in pregnancy for neuroprotection of the fetus
Crisis intervention for people with severe mental illnesses
Crisis interventions for people with borderline personality disorder
Criteria for prophylactic treatment, and choice of antibiotic regimen, to prevent Lyme disease following a tick bite
Critical incident audit and feedback to improve perinatal and maternal mortality and morbidity
Critically ill patients with delayed gastric emptying - is acupuncture effective?
Cross-modal supplementation for tinnitus
Cryoplasty for peripheral arterial disease
Cryotherapy following total knee replacement
Cryotherapy for acute non-specific neck pain
Cryotherapy for hepatocellular carcinoma
Cryotherapy for liver metastases
CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Cultural competence education for health professionals
Curcumin for maintenance of remission in ulcerative colitis
Customised versus population-based growth charts as a screening tool for detecting small for gestational age infants in low-risk pregnant women
Custom-made foot orthoses for the treatment of foot pain
Cutaneous antisepsis for prevention of intravascular catheter associated infection in newborn infants
Cyanoacrylate microbial sealants for skin preparation prior to surgery
Cycled light in the intensive care unit for preterm and low birth weight infants
Cycling infrastructure for reducing cycling injuries in cyclists
Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis
Cyclo-oxygenase (COX) inhibitors for preventing preterm labour
Cyclophosphamide for connective tissue disease associated interstitial lung disease
Cyclophosphamide versus ifosfamide for paediatric and young adult bone and soft tissue sarcoma patients
Cyclophosphamide versus methylprednisolone for treating neuropsychiatric involvement in systemic lupus erythematosus
Cyclophosphamides for multifocal motor neuropathy
Cyclosporin A for primary biliary cirrhosis
Cyroablation versus radiofrequency catheter ablation for AV nodal re-entrant tachycardia
Daclizumab for relapsing remitting multiple sclerosis
Daily oral iron supplementation during pregnancy
Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive mechanical ventilation
Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive mechanical ventilation
Damage control surgery for abdominal trauma
Danazol for pelvic pain associated with endometriosis
Dance movement therapy for dementia
Dance movement therapy for depression
Dance therapy for schizophrenia
Dance/movement therapy for improving psychological and physical outcomes in cancer patients
Darbepoetin for the anaemia of chronic kidney disease
Day centres for severe mental illness
Day hospital versus admission for acute psychiatric disorders
Day-surgery versus overnight stay surgery for laparoscopic cholecystectomy
D-dimer test for excluding the diagnosis of pulmonary embolism
Debridement for surgical wounds
Decentralised versus centralised governance of health services
Decentralising HIV treatment delivery in middle- and low-income countries
Decentralising HIV treatment in lower- and middle-income countries
Decision aids and the effect on choice for surgery and knowledge of treatment options for breast cancer patients
Decision aids for people facing health treatment or screening decisions
Decision support interventions for people making decisions about participation in clinical trials
Decompressive surgery for treating nerve damage in leprosy
Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
Deep anterior lamellar keratoplasty versus penetrating keratoplasty for treating keratoconus
Deep brain and cortical stimulation for epilepsy
Deep brain stimulation (DBS) for intractable trigeminal autonomic cephalalgias (TACs)
De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock
De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma
Deferasirox for managing iron overload in people with thalassaemia
Deferasirox for managing transfusional iron overload in people with sickle cell disease
Deflation of gastric band balloon in pregnancy for improving outcomes
Deflation of gastric band balloon in pregnancy for improving outcomes
Dehumidifiers for chronic asthma
Dehydroepiandrosterone (DHEA) for systemic lupus erythematosus
Dehydroepiandrosterone for menopausal women
Delayed antibiotics for respiratory infections
Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants
Deliberate hypotension with propofol under anaesthesia for functional endoscopic sinus surgery (FESS)
Delirium associated with commonly prescribed medicines
Delivering services to people with social anxiety
Delivery arrangements for health systems in low-income countries: an overview of systematic reviews
Delivery methods of education for people with type 2 diabetes.
Delivery of inhaled steroids in children - which is the most effective method of delivering drugs for asthmatic children?
Denosumab for the treatment and prevention of postmenopausal osteoporosis
Dental auxiliaries for dental care
Dental cavity liners for Class I and Class II resin-based composite restorations
Dental extractions prior to radiotherapy to the jaws for reducing post-radiotherapy dental complications
Dental implants in zygomatic bone for the rehabilitation of the severely deficient edentulous maxilla
Dental surgery for patients on anticoagulant therapy with warfarin
Department of Health's 'Let's get moving' physical activity care pathway for increasing physical activity
Depigmentation for improved quality of life in severe vitiligo
Depot versus daily administration of gonadotrophin-releasing hormone agonist protocols for pituitary down regulation in assisted reproduction cycles
Depot/long-acting injectable antipsychotic preparations for schizophrenia
Dermofasciectomy for Dupuytren’s contractures of the hand
Desensitisation therapy (allergen-specific immunotherapy) for atopic eczema
Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia
Desipramine for neuropathic pain in adults
Desmopressin acetate (DDAVP) for preventing and treating acute bleeds during pregnancy in women with congenital bleeding disorders
Desmopressin plus enuresis alarm for nocturnal enuresis
Desmopressin to decrease blood loss and blood transfusion requirements for liver resection
Deterioration in the home of a person with asthma — action by patient including when to call for GP, when to self-admit
Determine the long-term effects of prompted voiding on daytime urinary incontinence in nursing home residents and homebound frail older adults
Detoxification therapy for Lyme disease
Detoxification treatments for opiate dependent adolescents
Device modified trabeculectomy for glaucoma
Devices and dressings to secure peripheral venous catheters to prevent complications
Devices for preventing percutaneous exposure injuries caused by needles in healthcare personnel
Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin and school performance
Dexmedetomidine for procedural sedation in children
Dexmedetomidine for the management of awake fibreoptic intubation
Dextrose for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Diacerein for osteoarthritis
Diagnosis of gestational diabetes
Diagnostic accuracy of laparoscopy following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer
Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions
Dialysate sodium levels for chronic haemodialysis
Dialyser reuse for people with end-stage kidney disease requiring haemodialysis
Diaries for recovery from critical illness
Diclofenac with or without an antiemetic for acute migraine headaches in adults
Diclofenac with or without an antiemetic for acute migraine headaches in adults
Diet and dietary supplements for schizophrenia
Diet and exercise interventions for preventing gestational diabetes mellitus
Diet or exercise, or both, for weight reduction in women after childbirth
Dietary advice for reducing cardiovascular risk
Dietary advice with or without oral nutritional supplements for disease-related malnutrition in adults
Dietary and physical activity interventions on maternal weight in pregnant women for long term maternal and fetal outcomes
Dietary antioxidants and primary prevention of age related macular degeneration
Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Dietary flavonoid for preventing colorectal neoplasms
Dietary interventions (plant sterols, stanols, omega-3 fatty acids, soy protein and dietary fibers) for familial hypercholesterolaemia
Dietary interventions during recovery from Lyme disease
Dietary interventions for lowering cholesterol in dialysis patients
Dietary interventions for mineral and bone disorder in people with chronic kidney disease
Dietary interventions for multiple sclerosis
Dietary interventions for preventing complications in idiopathic hypercalciuria
Dietary interventions for recurrent abdominal pain in childhood
Dietary interventions for rheumatoid arthritis
Dietary interventions for weight loss and cardiovascular risk reduction in people of African ancestry
Dietary modifications for infantile colic
Dietary sodium manipulation and asthma
Dietary sodium modification on asthma control
Dietary supplements for chronic gout
Dietary supplements for established atopic eczema
Dietary supplements for preventing postnatal depression
Dietary supplements, herbal medicines, or other alternative medications for Lyme disease when taken in combination with conventional treatment,
Different antibiotic regimens for treating asymptomatic bacteriuria in pregnancy
Different antibiotic treatments for group A streptococcal pharyngitis
Different antibiotic treatments for group A streptococcal pharyngitis
Different antihypertensive strategies in patients with diabetes, nephropathy and a history of myocardial infarction for the treatment of hypertension and prevention of heart failure
Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth
Different doses of prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation
Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease
Different faecal calprotectin tests, for Inflammatory bowel disease
Different formats and timing of educational interventions for surgical patients
Different infusion durations for preventing platinum-induced hearing loss in children with cancer
Different intensities of glycaemic control for pregnant women with pre-existing diabetes
Different magnesium sulphate regimens for neuroprotection of the fetus for women at risk of preterm birth
Different methods of vascular occlusion for elective liver resection
Different referral patterns in primary care for the urinary incontinence patient
Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with depression
Different sized incisions for phacoemulsification in age-related cataract
Different sources of autologous mononuclear cells and stem cells for critical lower limb ischaemia
Different strategies for diagnosing gestational diabetes to improve maternal and infant health
Different strategies for using topical corticosteroids for established eczema
Different treatment regimens for magnesium sulphate for tocolysis in women in preterm labour for improving health outcomes
Different types of alarm in the managment of childhood nocurnal enuresis
Different types of dietary advice for women with gestational diabetes mellitus
Different types of implants for reconstructive breast surgery
Different types of intermittent pneumatic compression devices for preventing venous thromboembolism in patients after total hip replacement
Different types of practitioners and treatment response to acupuncture for migraine prophylaxis
Different unfractionated heparin doses for preventing arterial thrombosis in children undergoing cardiac catheterization.
Differential effects of D-hormone analogs and native vitamin D on falls
Differing dose of normobaric and hyperbaric oxygen therapy combined with other therapies for migraine and cluster headache
Digitalis for treatment of heart failure in patients in sinus rhythm
Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria
Dilute versus full strength formula in exclusively formula-fed preterm or low birth weight infants
Dimercaptosuccinic acid scan versus ultrasound in screening for vesicoureteral reflux among children with urinary tract infections
Dimethyl fumarate for multiple sclerosis
Direct comparisons between atypical antipsychotics for schizophrenia
Direct composite resin fillings versus amalgam fillings for permanent or adult posterior teeth
Direct renin inhibitors for preventing the progression of diabetic kidney disease
Direct thrombin inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in people with non-valvular atrial fibrillation
Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of venous thromboembolism following total hip or knee replacement
Direct versus indirect bonding for bracket placement in orthodontic patients
Directed preconception health programs and interventions for improving pregnancy outcomes for women who are overweight or obese
Directly observed therapy (DOT) compared with self-administered treatment for latent and/or active tuberculosis (TB) in difficult to manage people
Discharge planning from hospital to home
Disease management interventions for improving self-management in lower-limb peripheral arterial disease
Disease modifying anti-rheumatic drugs in people with cystic fibrosis-related arthritis
Disposable surgical face masks for preventing surgical wound infection in clean surgery
Dissection versus diathermy for tonsillectomy
Distal aortic perfusion during thoracoabdominal aneurysm repair for prevention of paraplegia
Distal iliotibial band lengthening for refractory greater trochanteric pain syndrome
Disulfiram for alcohol use disorder
Dithranol plus PUVA for psoriasis
Diuretics for heart failure
Diuretics for Ménière's disease or syndrome
Diuretics for respiratory distress syndrome in preterm infants
DMARDs for rheumatoid arthritis
Do ace inhibitors cause weight gain following stroke?
Do additional assessments improve accuracy in diagnosing autism among preschool children compared with signs and symptoms alone?
Do adults with psoriasis and psoriatic arthritis who use topical therapies who see non-medical healthcare professional have different outcomes on the Psoriasis Area and Severity Index (PASI) and service use?
Do alterations in diet help in asthma?
Do alternative / complementary treatments such as psychological techniques help in asthma?
Do antacids reduce postoperative pneumonitis?
Do antibiotics actually affect the course of toxoplasma retinochoroiditis?
Do antibiotics and antiseptics applied to the skin work in the treatment of eczema?
Do antidepressants improve negative symptoms in schizophrenia?
Do antipsychotic drugs cause permanent physical adverse effects?
Do antipsychotic drugs make learning difficult?
Do anti-TNFs increase the risk of lymphoma in rheumatoid arthritis patients?
Do automated/mechanical chest compression devices improve survival in adult out-of-hospital cardiac arrest?
Do bath additives work in the treatment of eczema?
Do bisphosphonates increase the risk of atrial fibrillation?
Do breathing exercises help in asthma?
Do breathing exercises help in asthma?
Do calcium channel blockers prevent acute tubular necrosis (ATN) in cadaveric kidney transplant recipients?
Do cardiac medications have an adverse effect on skin integrity?
Do certain antiepileptic drugs affect thyroid function?
Do certain antiepileptic drugs lead to clustering of seizures?
Do champions of pressure ulcer prevention improve pressure ulcer healing?
Do champions of pressure ulcer prevention improve pressure ulcer prevention?
Do cleansers reduce acne severity?
Do combination inhalers taken for asthma cause osteoporosis with long term use?
Do combined exercise and self-management programmes reduce pain and increase function in community-based patients with knee and hip osteoarthritis?
Do commercially available gaming devices (e.g Wii), in addition to routine therapy, improve exercise and mobility after stroke?
Do communication aids and software packages improve communication in patients with aphasia following a stroke?
Do community physiotherapy interventions change the incidence of pressure ulcers?
Do continuous insulin infusion pumps offer an advantage over traditional intermittent insulin injections in terms of pregnancy outcomes in women with type 1 diabetes?
Do corticosteroids for asthma in children cause excess weight gain?
Do Crisis or Outreach teams prevent relapse of psychosis?
Do cross-sector service interventions improve school attendance, reduce admissions, and parents? satisfaction and experience of care for children and young people with neurodisability?
Do current treatment interventions for amblyopia assure better vision for patients than if no treatment is administered?
Do delays in reporting prostate symptoms to GPs affect disease outcomes?
Do different insulin delivery systems allow me to make different lifestyle choices about diet and exercise
Do different propellants in inhalers for asthma predispose to migraine headaches?
Do differing levels of investment of resources by NHS trusts in staff training result in varying levels of success in the prevention of pressure sores?
Do drugs with potential antihyperanalgesic properties (clonidine, ketamine, lidocaine) reduce the incidence of postoperative pain and persistant postsurgical pain.
Do educational programmes/training packages, for people with diabetes and their carers, help control the condition, reduce anxiety and provide greater awareness of the complications of the condition?
Do epidurals increase the incidence of vaginal tears?
Do epilepsy medications affect memory in the long term?
Do epilepsy medications affect the liver in the long term?
Do epilepsy medications cause impotence?
Do epilepsy medications cause shaking limbs?
Do fitness regimens have adverse effects on asthma?
Do foot orthotics have any structural or functional effect on hip and knee osteoarthritis?
Do herbal medicines prevent asthma attacks?
Do herbal remedies (such as St John's Wort, Chinese medicine) provide an effective approach to tinnitus management ?
Do high plasma levels of trimethylamine (TMAO) gut flora metabolism of phosphatidylcholine cause cardiovascular disease?
Do homeopathic remedies help control asthma symptoms?
Do homeopathic remedies provide an effective approach to tinnitus management strategy?
Do house dust mites cause atopic eczema?
Do I have to take asthma control treatment every day even when I am feeling fine?
Do I need to take my preventer inhaler for asthma every day?
Do I really need to use the asthma preventer every day?
Do increased levels of glutamate cause tinnitus?
Do individual metabolic differences influence outcomes treatment in schizophrenia? In what way?
Do individuals with erythromycin/clindamycin resistant propionibacterial floras respond adequately when erythromycin or clindamycin are used without concomitant benzoyl peroxide?
Do inhaled corticosteroids for asthma predispose one to diabetes?
Do inhaled steroids taken for asthama cause weight gain?
Do inhaled streroids for asthma cause lichen planus or lupus of the gums?
Do inhalers for asthma affect teeth?
Do internet-based approaches (such as Facebook) provide an effective self-management strategy for young people with tinnitus?
Do internet-based approaches (such as online forums) deliver an effective self-management strategy for people with tinnitus?
Do interventions such as educating school staff help children with diabetes live a less restricted life during school time?
Do 'life time' spectacle wearers have a higher or lower chance of developing age-related macular degeneration?
Do long acting insulin analogues maintain glucose control better than NPH insulin in the long term?
Do low dose oral antibiotics with good lipophilic properties lead to adequate clinical efficacy through anti-inflammatory rather than anti-microbial action and in turn reduce likelihood of resistance emerging?
Do massage-based therapies improve functioning and wellbeing for children and young people with neurodisability?
Do medications that targets genes have better effects on prostate cancer treatment?
Do minor increases in heart rate and blood pressure caused by central nervous system stimulants in attention deficit hyperactivity disorder (ADHD) patients result in adverse cardiovascular effects
Do multi-dose insulin injection regimes adversely affect the quality of life of [i] children and adolescents and [ii] adults with Type 1 diabetes?
Do needle and syringe programmes for drug users have any unintended consequences?
Do nerve blocks offer any advantage over simple local anaesthetic infiltration for superficial procedures?
Do neuroprotective (e.g. bolus thiopentone) strategies improve outcome in intracranial surgery?
Do nonsteroidal anti-inflammatory drugs (NSAIDs) cause a risk of perioperative bleeding?
Do nutritional supplements reduce symptoms and improve functioning of children with Autistic Spectrum Disorder?
Do Omega 3 supplements alleviate psychotic symptoms?
Do patient/public and health professionals' views of urinary incontinence effect continence status?
Do patients who are withdrawing from olanzapine, taken for schizophrenia, experience withdrawal symptoms after more than 5 years of treatment?
Do patients with dystrophic epidermolysis bullosa who receive calcium and vitamin D supplements and/or bisphosphonates therapy have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive continuous dental care follow-up have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive continuous retinoid therapy have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive early gastrostomy have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive esophageal dilatations have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive nutritional supplements have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive periodic bone density monitorization have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive periodic cardiologic monitorization have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive periodic nephrologic monitorization have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who receive psychological interventions have better outcomes than those that do not?
Do patients with dystrophic epidermolysis bullosa who use adapted shoes/adapted insole/double socks have better outcomes than those that do not?
Do patients with in-situ squamous cell carcinoma and dystrophic epidermolysis bullosa who receive photodynamic therapy have better outcomes than those that receive other modalities of treatment?
Do patients with recurrent squamous cell carcinoma and dystrophic epidermolysis bullosa who receive amputation have better outcomes than those that receive local excision?
Do patients with squamous cell carcinoma and dystrophic epidermolysis bullosa who receive the sentinel node biopsy have better outcomes than those that do not?
Do people who have a first seizure need to see an epilepsy specialist for treatment?
Do people with specialist conditions receive the best practice pressure ulcer treatment at specialist centres compared to generalist services?
Do phosphodiesterase inhibitors help women with diabetes mellitus who have sexual dysfunction?
Do phosphodiesterase inhibitors improve erectile dysfunction in people with uncontrolled diabetes mellitus?
Do pressure redistributing devices reduce the development of pressure ulcers for those who are at risk of developing a pressure ulcer?
Do pressure stretches such as physiotherapy improve pressure ulcer healing?
Do preventer inhalers with steroids have to be used every day for children with asthma?
Do preventer inhalers with steroids have to be used every day for children with asthma?
Do prisms improve visual field loss after stroke?
Do probiotics significantly reduce trimethylaminuria (TMAU1) producing bacteria in the human intestine and does this result in clinically relevant decreases in TMA production, and thus body odour, in patients with TMAU1?
Do psychological interventions improve arthritis pain management?
Do psychological therapies decrease dependence on standard medication and promote full recovery in severe mental illness?
Do psychological therapies decrease relapse and re-hospitalizations in patients with severe mental illness?
Do rituximab or abatacept for rheumatoid arthritis increase the risk of infection?
Do seizure alarms for children with epilepsy reduce Sudden Unexpected Death in Epilepsy (SUDEPS)?
Do side effects to a certain anti-epileptic medication help predict side effects to other anti-epileptic medications?
Do single use laryngoscope blades improve patient safety?
Do slowing down, providing written material, allowing time for questions and using conversation partners help improve communication with people with aphasia following stroke?
Do social communication groups improve confidence in people with communication problems after stroke?
Do some antiepileptic drugs cause auras?
Do sound generators provide an effective management strategy for pulsatile tinnitus?
Do sound generators provide an effective tinnitus management strategy for children?
Do sound generators provide an effective tinnitus management strategy when used as part of a wider therapeutic approach or as a stand alone treatment?
Do sound generators provide an effective tinnitus management strategy? Which type of patients might benefit most and what is an effective prescription for usage?
Do sound generators provide an effective tinnitus management strategy? Which type of patients might benefit most and what is an effective prescription for usage? Here a comparison might be with Cognitive Behaviour Therapy.
Do spacers work as well as nebulisers in severe asthma attacks?
Do staffing levels have an impact on the incidence of pressure ulcers?
Do statins have a beneficial effect in preventing prostate cancer?
Do statins improve perioperative outcome?
Do steroid inhalers taken for asthma cause osteoporosis?
Do steroids lose any effectiveness used over a long period of time for asthma?
Do steroids taken for asthma cause osteoporosis in later life?
Do support surfaces help pressure ulcers to heal?
Do support surfaces prevent further tissue damage in patients with an existing pressure ulcer?
Do the adverse effects of antipsychotic drugs outweigh the benefits?
Do the long acting insulin analogues improve diabetes complications better than NPH insulin in the long term?
Do the meglitinide analogues reduce the morbidity and mortality from diabetes associated complications?
Do the newer antiepileptic drugs cause low bone mineral density?
Do thickened fluids cause dehydration after stroke?
Do treatments other than medication help asthma symptoms?
Do uterine fibroids cause infertility and should they be removed to increase fertility?
Do variations in GP awareness of prostate cancer affect outcomes?
Do variations in GP awareness of prostate cancer affect outcomes?
Do we have a way of reducing corneal scarring caused by shingles?
Do we have to have an operation to correct glaucoma?
Do you have different daily water requirements if you are taking epilepsy medication?
Doctors or mid-level providers for abortion
Does a brief period of preoperative exercise training improve outcomes after major surgery?
Does a combination of albuterol and Benadryl relieve distress in people who are thought to have food "intolerance's" and asthma?
Does a combination treatment of hormone therapy and chemotherapy for prostate cancer improve the disease outcome?
Does a 'day diary' to record activities etc., completed by visitors, help people with communication problems share what has been happening for people with stroke?
Does a digital rectal exam alone or in combination with other tests improve diagnosis of prostate cancer?
Does a high carbohydrate diet and the subsequent increased daily dose of insulin lead to more frequent and/or more severe hypoglycaemia in people with Type 1 diabetes?
Does a high carbohydrate diet cause weight increase in Type 1 and Type 2 diabetes
Does a higher sodium content IV fluid regimen for maintenance reduce the risk of developing hyponatraemia and volume depletion without increasing the risk of volume overload in hospitalised adults?
Does a lidocaine infusion help manage the pain of fibromyalgia?
Does a structured training programme speed up the achievement of continence (either/or faecal or urinary) for children and young people with neurodisability?
Does access to a specialist wound prevention service improve pressure ulcer prevention?
Does access to the latest diagnostic equipment improve outcomes for prostate cancer?
Does access to the latest treatment equipment improve outcomes for prostate cancer?
Does active pituitary monitoring post traumatic brain injury for children improve outcomes?
Does active surveillance work for treatment of prostate cancer?
Does active surveillance work for treatment of prostate cancer?
Does activity scheduling and physical exercise increase well being of patients with schizophrenia?
Does acupuncture help central pain or provide a holistic'well-being' effect for peoplel following a stroke?
Does acupuncture help in asthma?
Does acupuncture produce analgesia and is any or all of this a placebo effect?
Does acupuncture reduce the need for inhaled steroids in asthma?
Does additional information and emotional support improve outcomes in twin and triplet pregnancies?
Does Advair Diskus 500/50 taken for asthma cause musculoskeletal pain?
Does advice to parents for children with asthma on allergen avoidance help avoid asthma attacks?
Does air-conditioning help to overcome tinnitus-related insomnia?
Does allergen avoidance work in asthma?
Does ambulatory oxygen improve outcomes in idiopathic pulmonary fibrosis?
Does an enhanced perioperative care package improve outcomes?
Does anti-cyclic citrullinated peptide guide the management of patients with early rheumatoid arthritis?
Does applying methylated spirits to skin help prevent ulcers?
Does appropriate provision of wheelchairs to enable independent mobility for very young children improve their self-efficacy?
Does assessing risk factors affect my risk of being wrongly diagnosed with prostate cancer , and over- or under-treated?
Does avoidance of contact with animals reduce asthma severity?
Does avoidance of peanuts in early life reduce the risk of peanut allergy?
Does avoiding certain foods help to control asthma in children?
Does avoiding triggers help my asthma?
Does belonging to a religious movement help my schizophrenia?
Does Benfotiamine (form of Vit B1) prevent diabetes complications?
Does Benfotiamine (form of vitamin B1) prevent diabetes complications?
Does best practice in treatment take into consideration the range of risk from transient problem as the result of an operation to a lifetime of risk for those with spinal injury?
Does Botox improve function in activities of daily living following a stroke?
Does breastfeeding protect against allergic rhinitis during childhood?
Does breathing air through a salt pipe help to control asthma symptoms?
Does carer/family involvement in pressure ulcer prevention improve prevention?
Does change of environment for a person affect the prevalence of asthma?
Does changing geographical locations to a warmer climate help with asthma?
Does chiropracty improve gross/fine motor function of children with hemiplegia?
Does clothing affect Hidradenitis suppurativa?
Does communication training (for example motivational interviewing techniques) for diabetes specialists improve type 1 diabetes control?
Does complementary therapy help with quality of life in patients on active surveillance for prostate cancer?
Does consuming alcohol affect my risk of developing prostate cancer?
Does continuing beta-blocker treatment beyond 1 year after an MI improve outcomes for people with normal left ventricular systolic function?
Does continuous glucose monitoring in diabetes yield better self-management?
Does conventional (as opposed to tight) glycaemic control improve perioperative outcome?
Does counselling enable sufferers of thyroid eye disease to overcome depression associated with the facial disfiguiring associated with the disease?
Does debridement promote healing in patients with pressure ulcers?
Does delayed diagnosis and thus treatment of pernicious anaemia cause people to develop adverse effects such as peripheral neuropathy or sub-acute combined degeneration of the spinal cord?
Does depression screening improve depression outcomes in primary care?
Does diet have any effect on the severity of Hidradenitis suppurativa?
Does diet in pregnancy affect the genetic condition of the foetus in a family with known albinism?
Does direct access to a multidisciplinary team (MDT) by stroke patients in the community improve recovery?
Does drinking extra water promote weight loss?
Does drinking water reduce the frequency or severity of headaches?
Does early aggressive treatment at the first signs of acne alter the natural history of disease and reduce the need for further systemic therapy?
Does early detection lead to better visual outcome in thyroid eye disease?
Does early detection of prostate cancer give more effective treatment options?
Does early diagnosis and aggressive treatment influence the course of Hidradenitis sSuppurativa?
Does early diagnosis of refractive error improve long-term prognosis and promote faster, more effective treatment?
Does early involvement of care of the elderly and primary care in the management of elderly surgical patients improve outcome?
Does early revascularisation improve outcome in patients with diabetes and a foot ulcer?
Does early treatment with aggressive disease modifying drugs improve the prognosis for people with multiple sclerosis?
Does EBRT (external beam radiotherapy) for prostate cancer cause bone necrosis?
Does ECT for depression cause memory loss?
Does ECT for schizophrenai cause memory loss?
Does effective intranasal corticosteroid treatment of rhinitis reduce asthma exacerbations and costs?
Does epidural anaesthesia improve long-term outcomes after major elective surgery?
Does excessive coffee drinking affect prostate cancer risk?
Does exercise coaching help in the prevention of pressure ulcers?
Does exercise improve mood after stroke?
Does extending the use of pressure relieving mattresses on general wards improve prevention?
Does family presence during brain stem death (BSD) diagnosis increase consent to organ donation?
Does family therapy for schizophrenia reduce relapse?
Does functional electrical stimulation improve outcome after stroke?
Does general or regional anaesthetic cause post-operative cognitive decline?
Does gluten sensitivity in the absence of coeliac disease exist?
Does goal directed therapy improve outcome in anaesthesia care?
Does goal directed therapy improve outcomes in major abdominal surgery?
Does group exercise out of the home improve emotional wellbeing and mental health (and falls prevention)?
Does having a stoma (in a patient with Crohn's disease) cause drowsiness?
Does having had a vasectomy increase my risk of prostate cancer?
Does having to pay for asthma prescriptions reduce the effectiveness of treatment in controlling asthma?
Does Hidradenitis suppurativa make skin cancer more likely?
Does high morale within the stroke team service improve stroke recovery?
Does high quality care from carers/care staff improve outcomes for people with dementia?
Does home oxygen benefit people with chronic heart failure?
Does homeopathy help in asthma?
Does hydrotherapy improve physical fitness, mood, fatigue and spasticity for people following a stroke?
Does hyperventilating help reduce asthma symptoms?
Does hypotensive resuscitation improve outcome in active haemorrhage?
Does identification of microalbuminuria during pregnancy offer the opportunity for appropriate pharmacological treatment to prevent progression to pre-eclampsia in women with pre-existing diabetes?
Does improved nutrition and hydration promote prevention in people at risk of pressure ulcers?
Does improving diet (eating) and hydration (drinking) promote pressure ulcer healing?
Does improving diet promote healing?
Does improving nutrition and hydration help in the healing of pressure ulcers?
Does increased patient awareness of Tissue Viability Nurses services improve pressure ulcer healing?
Does increasing the number of specialist Tissue Viability Nurses improve prevention of pressure ulcers?
Does increasing the number of specialist Tissue Viability Nurses improve ulcer healing?
Does incresing patient education awareness of new technological developments improve outcomes for patients with diabetes?
Does intensive physiotherapy (e.g. stroking/moving limbs - maybe using volunteers) early after stroke help recovery?
Does intraoperative FiO2 impact on clinical outcomes in anaesthesia care?
Does investigation of possible allergies improve the treatment of asthma?
Does involvement of parents in the care plan improve the care of children with diabetes?
Does involvement of the GP (General Practitioner) during stroke admission help improve medium and long term outcomes?
Does long term use of steroids for asthma increase the risk of arteriosclerosis?
Does long-term low-dose trimethoprim promote wound healing in patients with severe forms of epidermolysis bullosa and how well is low dose trimethoprim tolerated?
Does magnesium supplement provide an effective way to reduce tinnitus?
Does maintaining high normal concentrations of serum potassium and magnesium improve outcome after cardiac surgery?
Does managing all thoracic epidurals in an High Dependency Unit improve outcome?
Does meditation decrease the risk of developing tinnitus?
Does memantine reduce progression of functional disability in people with severe vascular dementia?
Does methotrexate monotherapy increase the risk of malignancy in rheumatoid arthritis?
Does mild renal impairment get worse if a person takes lithium for mood disorders?
Does mindfulness based cognitive therapy prevent relapse of depression?
Does moving to a sunnier climate help asthma?
Does multilevel surgery improve Quality of Life of children with cerebral palsy?
Does multimodal monitoring improve outcome in head injury?
Does multivessel primary percutaneous coronary intervention (PPCI), at the time of presentation of people with acute ST-segment elevation myocardial infarction, confer an advantage over a strategy of 'culprit vessel only' primary PCI, followed by further elective revascularisation driven by symptoms and evidence of ischaemia?
Does my risk of prostate cancer depend on how sexually active I am, or have been?
Does negative pressure wound therapy with appropriate dressing improve the healing of pressure ulcers, compared with the use of dressing alone in adults with pressure ulcers?
Does noise exposure increase the risk of developing tinnitus? How can this information inform prevention strategies.
Does not having to pay for prescription medication for chronic asthma help improve symptoms?
Does not paying for medication for asthma increase compliance?
Does nutritional supplementation with vitamin D improve motor function in children and young people with neurodisability?
Does one day in bed and three back using your wheelchair change the rate of healing compared to bed rest?
Does outdoor walking (in groups) improve physical fitness, mood and fatigue after stroke?
Does patient information on drugs used to treat prostate cancer have any effect on outcomes?
Does perioperative paperwork compromise patient safety?
Does perioperative steroid attenuate activation of the coagulation cascade in patients undergoing repair of aortic dissection?
Does personal hygiene have any effect on the severity of Hidradenitis suppurativa?
Does poly-pharmacy in older patients with severe mental illness cause greater adverse events?
Does prehospital ultrasound improve survival of the trauma patient?
Does primary chemo-irradiation improve loco-regional control and overall survival? squamous cell carcinoma of the Head & Neck and for which specific anatomical sites?
Does promoting public positive attitudes towards disability improve participation in recreation and leisure activities for children and young people with neurodisability?
Does propofol offer any advantage over thiopentone in patients who are to be intubated?
Does proton beam radiotherapy offer a safer and effective alternative to conventional radiotherapy in the treatment of retinoblastoma, especially for children under 1 year of age?
Does psychodynamic therapy really make a difference to symptoms, functioning and quality of life of people with schizophrenia?
Does pulmonary rehabilitation improve outcomes for people with idiopathic pulmonary fibrosis?
Does radio frequency ablation (RFA) facet joint ablation confer long-term benefits compared to non-interventional treatment?
Does rapid sequence induction improve outcome in patients at risk of aspiration?
Does reducing glucose variability reduce long term complications of type 1 diabetes even when average levels are not reduced?
Does reduction in stress reduce risk of stroke?
Does regional anaesthesia improve long-term outcomes after surgery?
Does regional anaesthesia reduce the risk of cancer recurrence?
Does regular turning of patients in bed promote healing of pressure ulcers?
Does regular turning of patients in beds promote healing of pressure ulcers?
Does regular use of emollients reduce disease relapse in atopic eczema?
Does removal of pets influence disease activity in established atopic eczema?
Does risperidone worsen psoriasis?
Does routine additional information from educational settings (such as nursery or school) improve accuracy in diagnosing autism among children or young people up to the age of 19 compared with signs and symptoms alone?
Does routine oxygen supplementation in patients with acute stroke improve outcome?
Does routine review of people with asthma improve outcome?
Does salbutamol used to treat asthma cause cramps?
Does screening and following recommended best practice, such as using orthotics, postural management, and surgery reduce hip dislocation/scoliosis in children with cerebral palsy?
Does self-management education for children with epilepsy change seizure frequency?
Does Seretide affect pregnancy?
Does serial PSA measurement in patients with prostate cancer accurately monitor disease progression?
Does serial PSA measurement in patients with prostate cancer accurately monitor disease progression?
Does setting national targets for blood glucose levels discourage health professionals setting targets according to individual needs/situations?
Does setting targets effectively reduce the incidence of pressure ulcers?
Does sleep or the lack of sleep affect the way your epilepsy medication works
Does smoking affect Hidradenitis suppurativa?
Does smoking increase the risk of Thyroid Eye Disease (TED)?
Does social support in the early acute phase of schizophrenia help reduce relapse?
Does sodium supplement provide an effective way to reduce tinnitus?
Does specialist antenatal care for women with twin and triplet pregnancies improve outcomes for women and their babies?
Does staff training in cultural competence at an individual and organisational level improve the experience of care and chance of recovery from schizophrenia in Black and Minority Ethnic groups, and reduce staff burnout?
Does statin use reduce the risk of hip fracture?
Does stem cell technology (e.g. for hair cell regeneration) provide an effective pipeline to develop new medical interventions for treating tinnitus?
Does stress trigger a flare of Hidradenitis suppurativa?
Does strontium ranelate increase vascular and neurological side-effects in postmenopausal osteoporosis?
Does sunlight exposure reduce acne severity?
Does supplementation of vitamin D in pregnant women and breast feeding mothers prevent multiple sclerosis?
Does sweating make Hidradenitis suppurativa worse and could antiperspirant or deodorants be helpful?
Does switching from brand-name to generic antiepileptic epilepsy drugs increase risk of seizures?
Does systemic HRT use in women whose primary complaint was not urinary incontinence worsen urinary symptoms?
Does taking steroids for asthma cause depression, or add to feeling depressed?
Does taking steroids for asthma stop me losing weight?
Does Tegretol cause balance problem in schizophrenia?
Does testing for allergies lead to better treatment for children with asthma?
Does the addition of counters to inhalers for asthma improve use by the patient?
Does the addition of positron emission tomography/computed tomography (PET/CT) to the routine investigation and assessment of patients with melanoma yield clinical and economic benefits?
Does the addition of psychological interventions (e.g. counselling, support) to patients receiving cosmetic camouflage improve their quality of life?
Does the addition of the oral agent metformin to insulin treatment in children and young people with type 1 diabetes improve outcomes?
Does the addition of zinc to topical erythromycin confer additional benefit in the treatment of acne?
Does the decision to deliver an infant by caesarean section have an impact on maternal and neonatal outcomes when there is a category 2 level of urgency for Caesarean Section (CS)?
Does the decision to deliver an infant by caesarean section have an impact on maternal and neonatal outcomes when there is a category 2 level of urgency for Caesarean Section (CS)?
Does the diet administered through gastrostomy influence nutrition and Quality of Life, and improve digestive functioning in children and young people with neurodisability who have had gastrostomy and use enteral feeding?
Does the education of health and social care staff on prevention lead to a reduction in the incidence of pressure ulcers?
Does the education of health and social staff on prevention lead to a reduction in incidence of pressure ulcers andif so, which are the most effective education programmes?
Does the grade of the anaesthetist affect outcome in emergency surgery patients?
Does the introduction of hospital systems that ensure all hospital healthcare professionals involved in prescribing and delivering IV fluid therapy are appropriately trained in the principles of fluid prescribing
Does the labelling of patients or their families as difficult or non-compliant impact on pressure ulcer prevention?
Does the labelling of patients or their families as difficult or non-compliant impact on pressure ulcer treatment outcomes?
Does the lack of knowledge of the range of treatments for different types of prostate cancer affect outcomes?
Does the long-term use of earplugs play a causal role in developing tinnitus?
Does the management of co-existing neck problems improve outcomes for patients with balance disorders?
Does the method of insulin delivery (injection vs. pump) have any impact on rates of complications?
Does the pain of blood glucose testing affect the willingness of patients, especially children, to monitor their blood glucose levels?
Does the provision of specialists/cancer support groups or specialist health care workers who provide more information on prostate cancer treatment improve outcomes?
Does the timing and intensity of therapies alter the effectiveness of therapies for infants and young children with neurodisability, including those without specific diagnosis?
Does the transfer of expertise from specialist units to more general settings result in better pressure ulcer prevention?
Does the transfer of expertise from specialist units to more general settings result in better treatment outcomes?
Does the use of cuffed endotracheal tubes (ET) tubes in paediatric patients improve safety?
Does the use of epiaortic scanning prevent embolic stroke in cardiac surgery?
Does the use of modern technology increase the risk of age related macular degeneration (AMD)?
Does the use of short acting opoids in rapid sequence induction decrease morbidity by improving airway control?
Does the use of skin care regimes diminish the likelihood of pressure ulcer occurrence?
Does the use of ultrasound affect safety and efficiency in regional anaesthesia?
Does the use the EOS 2D/3D imagingsystem for 3D reconstruction provides benefit for diagnosis or treatment planning?
Does the way a bed is made or the type of bedding have an impact on ulcer healing?
Does the way information is provided affect quality of diagnosis, choice of appropriate treatment or outcome for patients with prostate cancer?
Does the way information is provided to patients with mental health conditions effect the outcome of treatment?
Does thrombolysis have an adverse effect on cognitive abilities?
Does TNF-blockade therapy exacerbate psoriatic arthritis?
Does tooth brushing influence the development and progression of non-inflammatory gingival recession?
Does training on simulators improve clinical performance?
Does training professionals to recognise signs and symptoms of autism lead to earlier assessment of needs and earlier diagnosis (and by implication reduce morbidity/improve health outcomes) among children and young people with suspected autism compared with no training?
Does trampolining improve balance and coordination in children and young people with neurodisability?
Does treating a pressure ulcer in the same manner as a crush injury promote ulcer healing?
Does treatment for stress and panic reduce asthma attacks?
Does treatment of periodontal disease improve glycaemic control in people with diabetes?
Does treatment of type 1 diabetics by specialists (e.g. doctors, nurses, dieticians, podiatrists, ophthalmologists and psychologists) trained in person-centred skills provide better blood glucose control, patient satisfaction and self-confidence in management of type 1 diabetes, compared to treatment by non specialists with standard skills?
Does treatment with immunosuppressants help patients with vitiligo?
Does under treatment of pernicious anaemia cause cyclic cognitive impairment for patients?
Does unopposed oestrogen therapy have a protective effect against osteoarthritis?
Does use of enteral peg feeding by young children with neurodisability with or without speech and language therapy impact on their ability to develop useful vocal communication skills?
Does using a standing frame regularly help to prevent pressure sores?
Does using inhalers for asthma cause acid indigestion?
Does using instrumented gait analysis improve decision-making about treatments compared to clinical assessment alone for children and young people with cerebral palsy?
Does using smokeless tobacco stop the incidence of oropharyngeal cancer and periodontal disease?
Does variation in treatment for patients with psychosis, which is often trail and error, affect compliance?
Does visual feedback improving movement during rehabiliation exercises following a stroke?
Does Vitamin D production, following exposure to sunlight provide protection against prostate cancer?
Does weight reduction improve symptoms in people with Hidradenitis suppurativa?
Does xenon anaesthesia improve neurological outcomes after cardiac arrest and in other settings?
Does Yoga help in asthma?
Does zinc supplement provide an effective way to reduce tinnitus?
Dopamine agents for hepatic encephalopathy
Dopamine agonists for hyperprolactinaemia
Dopamine agonists for restless legs syndrome
Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies
Dopamine versus placebo for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Dopexamine versus placebo for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Dosages scheduling of taxanes and the optimal use of taxanes in early breast cancer
Dose regimens, length of treatment, and duration of response of oestrogen and progesterone add-back therapy in preventing bone mineral density loss in patients taking gonadotrophin-releasing hormone analogues for endometriosis
Doses and administration routes for individual triptans and acute cluster headaches
Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage kidney disease
Double-bundle versus single-bundle reconstruction for anterior cruciate ligament rupture in adults
Double-stapled anastomosis versus mucosectomy and handsewn anastomosis in ileal pouch-anal anastomosis for ulcerative colitis or familial adenomatous polyposis
Down titration and discontinuation strategies of tumor necrosis factor blocking agents for rheumatoid arthritis in patients with low disease activity
Doxycycline for hip or knee osteoarthritis
Doxycycline plus ivermectin versus ivermectin alone for treating onchocerciasis
D-Penicillamine for preventing retinopathy of prematurity in preterm infants
Drainage versus no drainage for lower limb arterial surgery
Drainage, irrigation and fibrinolytic therapy (DRIFT) for post-haemorrhagic hydrocephalus in preterm infants
Drama therapy for schizophrenia or schizophrenia-like illnesses
DRCgs for treating paracoccidioidomycosis
Dressings and securement devices for central venous catheters (CVC)
Dressings and topical agents for preventing pressure ulcers
Dressings for superficial and partial thickness burns
Dressings for the prevention of surgical site infection
Dressings for treating foot ulcers in people with diabetes: an overview of systematic reviews
Driving assessment for maintaining mobility and safety in drivers with dementia
Driving is a risk in patients with sleep-related epilepsy
Drug therapies for reducing gastric acidity in people with cystic fibrosis
Drug therapy for delirium in terminally ill adult patients
Drug therapy for nocturia
Drug therapy for obstructive sleep apnoea in adults
Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease
Drug therapy for preventing post-dural puncture headache
Drug therapy for symptoms associated with anxiety in adult palliative care patients
Drug therapy for the management of cancer related fatigue
Drug therapy for treating post-dural puncture headache
Drug treatment for faecal incontinence in adults
Drug treatment for lower urinary tract symptoms in women with voiding dysfunction
Drug treatment for nocturnal enuresis
Drug treatment for spinal muscular atrophy type I
Drug treatment for spinal muscular atrophy types II and III
Drug treatment for troublesome postural hypotension in people with diabetes and autonomic neuropathy
Drug-eluting bead transarterial chemoembolisation for unresectable hepatocellular carcinoma
Drugs and pacemakers for vasovagal, carotid sinus and situational syncope
Drugs for amoebic colitis
Drugs for nocturia in adults
Drugs for nocturnal enuresis in children (other than desmopressin and tricyclics)
Drugs for preventing red blood cell dehydration in people with sickle cell disease
Drugs for the prevention of postoperative urinary retention in adults
Drugs for the treatment of nausea and vomiting in adult patients in the emergency department setting
Drugs for treating giardiasis
Drugs for treating urinary schistosomiasis
Drugs for treatment of very high blood pressure during pregnancy
Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis
Drugs to treat urinary incontinence in the elderly
Dry bed training for nocturnal enuresis
Duloxetine depression
Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia
Duloxetine versus other anti-depressive agents for depression
Duplex ultrasound for the diagnosis of symptomatic deep vein thrombosis in the lower limb
Duration of intravenous antibiotic therapy in people with cystic fibrosis
Duration of treatment for asymptomatic bacteriuria during pregnancy
Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism
Dynamic exercise programs (aerobic capacity and/or muscle strength training) in rheumatoid arthritis
Ear drops for the removal of ear wax
Early (< 8 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants
Early (sentinel lymph node biopsy-guided) versus delayed lymphadenectomy in melanoma patients with lymph node metastases
Early additional food and fluids for healthy breastfed full-term infant
Early administration of inhaled corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonates
Early amniotomy and early oxytocin for prevention of, or therapy for, delay in first stage spontaneous labour compared with routine care
Early and late renal adverse effects after potentially nephrotoxic treatment for childhood cancer
Early compared with delayed oral fluids and food after caesarean section
Early developmental intervention programmes post-hospital discharge to prevent motor and cognitive impairments in preterm infants
Early erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants
Early excision and grafting for burns
Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)
Early intervention (mobilization or active exercise) for critically ill patients in the intensive care unit
Early intervention with oral isotretinoin versus alternative treatments for moderate or mild acne
Early intervention with systemic treatments for psoriasis
Early interventions by cardiac rehabilitation services following acute myocardial infarction
Early interventions with a stepped procedure in children with PTSD
Early lens extraction compared to standard treatment in acute primary angle closure
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
Early nutritional therapy for malnourished or nutritionally at-risk adult medical inpatients
Early palliative care for improving quality of life and survival time in adults with advanced cancer
Early prediction of outcome of activities of daily living after stroke
Early pregnancy assessment units
Early referral to specialist nephrology services for preventing the progression to end-stage kidney disease
Early removal versus expectant management of central venous catheters in neonates with bloodstream infection
Early routine endoscopic retrograde cholangiopancreatography strategy versus early conservative management strategy in acute gallstone pancreatitis
Early skin-to-skin contact for mothers and their healthy newborn infants
Early supported discharge in patients with hip fracture who are admitted from a care home
Early treatment of preclinical hypothyroidism
Early trophic feeding versus enteral fasting for very preterm or very low birth weight infants
Early use of inhaled corticosteroids in the emergency department treatment of acute asthma
Early versus delayed dressing removal after primary closure of clean and clean-contaminated surgical wounds
Early versus delayed dressing removal for surgical wounds
Early versus delayed erythropoietin for the anaemia of end-stage kidney disease
Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis
Early versus delayed laparoscopic cholecystectomy for acute gallstone pancreatitis
Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis
Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic
Early versus delayed mobilisation for aneurysmal subarachnoid haemorrhage
Early versus delayed post-operative bathing or showering to prevent wound complications
Early versus delayed refeeding for children with acute diarrhoea
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome
Early versus late administration of amino acids in preterm infants receiving parenteral nutrition
Early versus late antiepileptic drug withdrawal for people with epilepsy in remission
Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants
Early versus late tracheostomy for critically ill patients
Echinacea for preventing and treating the common cold
Economic incentives to enhance safety behaviour in workers for preventing occupational injuries
ECT for schizophrenia
Eculizumab for treating patients with paroxysmal nocturnal hemoglobinuria
Edaravone for acute intracerebral haemorrhage
Edaravone for acute ischaemic stroke
Edaravone for traumatic brain injury
Education for contraceptive use by women after childbirth
Education interventions for adults who attend the emergency room for acute asthma
Education of health professionals for preventing diabetic foot ulceration
Education of patients about to undergo laparoscopic cholecystectomy
Educational and behavioural interventions for anticoagulant therapy in patients with atrial fibrillation
Educational and skills-based interventions for preventing relationship and dating violence in adolescents and young adults
Educational games for health professionals
Educational interventions for adults to prevent readmission and complications following cardiovascular surgery;Symptoms
Educational interventions for asthma in adults
Educational interventions for improving the skills of medical practitioners to detect, diagnose, and manage people with cognitive impairment and dementia
Educational outcomes of atomoxetine in childhood attention deficit-hyperactivity disorder (ADHD)
Educational programmes for primary prevention of skin cancer
Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea
EEG for children with complex febrile seizures
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naive individuals
Effect of antibiotic treatment on the results of serological tests for Lyme disease
Effect of cocoa on blood pressure
Effect of duration (3 vs. 6 months) of long-term pituitary down-regulation before in vitro fertilisation for women with endometriosis on pregnancy rates
Effect of gastric banding on gastro-oesophageal reflux symptoms
Effect of lip bumpers on mandibular arch dimensions
Effect of longer-term modest salt reduction on blood pressure
Effect of near vision tasks on visual acuity in children with amblyopia
Effect of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive sleep apnoea
Effect of partogram use on outcomes for women in spontaneous labour at term
Effect of phenytoin and phenobarbital on bone mineral density in children
Effect of pre-exchange albumin infusion on neonatal hyperbilirubinaemia and long-term developmental outcomes
Effect of restricted pacifier use in breastfeeding term infants for increasing duration of breastfeeding
Effect of steroidal contraceptives on bone fractures in women
Effect of stimulant medication on gray matter volumes in attention deficit-hyperactivity disorder (ADHD) patients
Effect of testing for cancer on cancer- and venous thromboembolism (VTE)-related mortality and morbidity in patients with unprovoked VTE
Effect of time from infection to commencement of treatment on Lyme disease outcomes
Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes
Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes
Effective interventions for managing physical health of people with schizophrenia in general practice
Effective interventions for preventing and treating kidney disease in Henoch-Schonlein Purpura (HSP)
Effective interventions for preventing infection in nephrotic syndrome
Effective interventions for primary vesicoureteric reflux
Effective interventions to prevent bone disease in kidney transplant recipients
Effective methods of communication at first consultation visit for women with breast cancer?
Effective physical interventions to treat depression in dialysis patients
Effective psychosocial interventions to treat depression in dialysis patients
Effective treatments for truncal acne
Effectiveness and acceptability of interventions for moist desquamation in radiotherapy patients
Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers
Effectiveness and impact of consumer education initiatives for urinary incontinenece
Effectiveness and safety of first-line tenofovir + emtricitabine + efavirenz for patients with HIV
Effectiveness and safety of procalcitonin evaluation for reducing mortality in adult patients with sepsis, severe sepsis and septic shock
Effectiveness of a second acupuncture treatment in improving migraine
Effectiveness of antiretroviral therapy in HIV-infected children under 2 years of age
Effectiveness of debridement of diabetic foot ulcers
Effectiveness of different nursing handover styles for ensuring continuity of information in hospitalised patients
Effectiveness of different nursing handover styles for ensuring continuity of information in hospitalised patients
Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent)
Effectiveness of different types of acupuncture for migraine prophylaxis
Effectiveness of early in comparison to late(r) treatment in children with amblyopia or its risk factors
Effectiveness of external inspection of compliance with standards in improving healthcare organisation behaviour, healthcare professional behaviour or patient outcomes
Effectiveness of lower-dose combined oral contraceptives in women with IBD following bowel resection
Effectiveness of Nicotine Replacement Therapy in Reducing the Risk of Nicotine Exposure in Pregnant Minority Smokers NCT00341432 Pilot study of nicotine replacement for smoking cessation during pregnancy. NCT00888979
Effectiveness of nitrates compared to percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) for stable angina
Effectiveness of organisational infrastructures to promote evidence-based nursing practice
Effectiveness of posterior decompression techniques compared to conventional laminectomy for lumbar stenosis
Effectiveness of post-operative management strategies for adults with dementia following hip fracture surgery
Effectiveness of surgery with or without multimodality treatment in patients with N2 lung cancer
Effectiveness of systematic screening for the detection of atrial fibrillation
Effectiveness of the Valsalva Manoeuvre for reversion of supraventricular tachycardia
Effectiveness of the various components of preconception counselling to reduce adverse pregnancy outcome in women with epilepsy
Effectiveness of topical administration of opioids in palliative care
Effectiveness of vocational rehabilitation intervention on the return to work and employment of persons with multiple sclerosis
Effects and safety of periconceptional folate supplementation for preventing birth defects
Effects of etanercept on malignancy for rheumatoid arthritis
Effects of hormonal suppression, either before or after surgery, on endometriosis-associated pain and disease severity
Effects of long acting inhaled anticholinergics on cardiovascular events and mortality among vulnerable subgroups at the highest risk of systemic anticholinergic effects
Effects of long term pituitary down-regulation using GnRH agonists before in vitro fertilisation in women with endometriosis on the incidence of fetal abnormalities
Effects of long term pituitary down-regulation using GnRH agonists before in vitro fertilisation in women with endometriosis on the rate of multiple pregnancy
Effects of oral stimulation for oral feeding in preterm infants
Effects of peri-operative nonsteroidal anti-inflammatory drugs on postoperative kidney function for adults with normal kidney function
Effects of preventive oral supplementation with iron or iron with folic acid for women following childbirth
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome
Effects of targeting higher versus lower arterial oxygen saturations on death or disability in preterm infants
Efficacy and safety of Chinese herbal therapies for atopic eczema
Efficacy and safety of coal tar for chronic plaque psoriasis
Efficacy and safety of fibre-enriched formulations in acute pancreatitis compared to fibre-free formulas
Efficacy and safety of Grenz rays for psoriasis
Efficacy and safety of home UVB therapy for psoriasis compared to treatment in hospital
Efficacy and safety of intravenous immunoglobulin for atopic eczema, especially in patients who are not resistant to other systemic treatments
Efficacy and safety of leflunomide for atopic eczema
Efficacy and safety of leukotriene inhibitors (anti-leukotrienes) for atopic eczema
Efficacy and safety of methotrexate for atopic eczema
Efficacy and safety of oral mycophenolate mofetil for atopic eczema
Efficacy and safety of photodynamic therapy for acne
Efficacy and safety of wet-wraps for long-term treatment of atopic eczema
Efficacy of dental prophylaxis (rubber cup) for the prevention of caries and gingivitis
Efficacy of directional-microphone hearing aids
Efficacy of dithranol compared to topical vitamin D preparations (calcipotriol, calcitriol, tacalcitol) for chronic plaque psoriasis
Efficacy of emollients for chronic plaque psoriasis
Efficacy of intranasal corticosteroids for acute sinusitis
Efficacy of programmable analog hearing aids
Efficacy of Psychostimulant Drugs for Amphetamine Abuse or Dependence
Efficacy of psychostimulant drugs for amphetamine abuse or dependence
Efficacy of retinoids in the treatment of psoriasis
Efficacy of topical salicylic acid for chronic plaque psoriasis
Efficacy, tolerability, and safety of extended-release, topical, and novel anti-muscarinic agents for urinary incontinence in frail and institutionalised older people
Efficacy, tolerability, and safety of medications used to prevent urinary incontinence for extended periods (beyond 6 months)
Eicosapentaenoic acid (EPA, an omega-3 fatty acid from fish oils) for the treatment of cancer cachexia
Eight week cardiac rehabilitation service for people with stable angina
Elastic compression stocking for prevention of deep vein thrombosis
Elective birth at 37 weeks? gestation for women with an uncomplicated twin pregnancy
Elective preterm birth for fetal gastroschisis
Elective repeat caesarean section versus induction of labour for women with a previous caesarean birth
Elective surgery versus clinical observation for focal liver lesions incidentally detected and supposed to be benign
Elective versus symptomatic intravenous antibiotic therapy for cystic fibrosis
Electric fans for reducing adverse health impacts in heatwaves
Electrical stimulation with non-implanted electrodes for overactive bladder in adults
Electrical stimulation with non-implanted electrodes for urinary incontinence in adults
Electrical stimulation with non-implanted electrodes for urinary incontinence in men
Electro-coagulation for liver metastases
Electroconvulsive therapy (ECT) for schizophrenia
Electroconvulsive therapy for the depressed elderly
Electromagnetic field stimulation for treating delayed union or non-union of long bone fractures in adults
Electromagnetic fields for treating osteoarthritis
Electromagnetic therapy for treating pressure ulcers
Electromagnetic therapy for treating venous leg ulcers
Electromagnetic treatment for urinary incontinence in adults
Electromechanical and robot-assisted arm training for improving generic activities of daily living, arm function, and arm muscle strength after stroke
Electromechanical gait training after stroke
Electromechanical-assisted training for walking after stroke
Electronic cigarettes for smoking cessation and reduction
Electropalatography for articulation disorders associated with cleft palate
Electrotherapy for neck pain
Elemene for the treatment for lung cancer
Elevation of the head during intensive care management in adult patients with severe traumatic brain injury
Email for clinical communication between healthcare professionals
Email for clinical communication between patients/caregivers and healthcare professionals
Email for communicating results of diagnostic medical investigations to patients
Email for the coordination of healthcare appointments and attendance reminders
Email for the provision of information on disease prevention and health promotion
Embolisation for pulmonary arteriovenous malformation
Emergency cricothyroidotomy for airway management
Emergency ultrasound-based algorithms for diagnosing blunt abdominal trauma
Empiric antibiotic coverage of atypical pathogens for community-acquired pneumonia in hospitalized adults
Empirical antibiotics targeting Gram-positive bacteria for the treatment of febrile neutropenic patients with cancer
Enamel etching for bonding fixed orthodontic braces
Enamel matrix derivative for periodontal regeneration in teeth with furcation involvement
Endobronchial valves for lung volume reduction in emphysema
End-of-life care pathways for improving outcomes in caring for the dying
Endoluminal gastroplication for gastro-oesophageal reflux disease (GORD)
Endometrial injury in women undergoing assisted reproductive techniques
Endometrial resection and ablation techniques for heavy menstrual bleeding
Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding
Endometriosis: an overview of Cochrane Reviews
Endorectal advancement flap vs. other surgical techniques for cryptoglandular or Crohn's fistula-in-ano
Endoscopic radiofrequency therapy of the anal sphincter for faecal incontinence
Endoscopic balloon dilatation for subglottic or tracheal stenosis
Endoscopic Bipolar Radiofrequency Ablation for treating biliary obstructions caused by cholangiocarcinoma or pancreatic adenocarcinoma
Endoscopic drainage with or without endo-ultrasonography for pancreatic pseudocyst
Endoscopic injection of cyanoacrylate glue versus other endoscopic procedures for acute bleeding gastric varices in patients with portal hypertension
Endoscopic or surgical intervention for painful obstructive chronic pancreatitis
Endoscopic release for carpal tunnel syndrome
Endoscopic third ventriculostomy (ETV) for idiopathic normal pressure hydrocephalus (iNPH)
Endoscopic thoracic sympathectomy (ETS) for primary facial blushing
Endothelial keratoplasty versus penetrating keratoplasty for Fuchs endothelial dystrophy
Endothelial progenitor cell capture stents versus drug-eluting stents for angina or acute coronary syndrome
Endothelin receptor antagonists for persistent pulmonary hypertension in term and late preterm infants
Endothelin receptor antagonists for pulmonary arterial hypertension
Endothelin receptor antagonists for subarachnoid hemorrhage
Endovascular repair of abdominal aortic aneurysm
Endovascular repair versus open repair for inflammatory abdominal aortic aneurysms
Endovascular revascularisation versus conservative management for intermittent claudication
Endovascular stentgrafting of popliteal aneurysms
Endovascular treatment for ruptured abdominal aortic aneurysm
Endovascular versus conventional medical treatment for uncomplicated chronic type B aortic dissection
Endovascular versus open repair of asymptomatic popliteal artery aneurysm
Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus conventional surgery for great saphenous vein varices
Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus open surgery for great saphenous vein varices
Endovenous ablation therapy (LASER or radiofrequency) or foam sclerotherapy versus conventional surgical repair for short saphenous varicose veins
Endovenous thermal ablation for healing venous ulcers and preventing recurrence
Enemas during labour
Energy source instruments for laparoscopic colectomy
Enhanced care by generalists for functional somatic symptoms and disorders in primary care
Enhanced external counterpulsation
Enhanced external counterpulsation (EECP) for stable angina (CCS Grade IV)
Enhanced glucose control for preventing and treating diabetic neuropathy
Enhancing partner support to improve smoking cessation
Entecavir for chronic hepatitis B
Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy
Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy
Enteral iron supplementation in preterm and low birth weight infants
Enteral nutrition compared with glucocorticosteroid treatment in adults and children with Crohn's disease
Enteral nutrition formulations for acute pancreatitis
Enteral tube feeding for cystic fibrosis
Enuresis alarm treatment for children and young people who are partial or non-responders to desmopressin
Environmental and behavioural interventions for reducing physical activity limitation in community-dwelling visually impaired older people
Environmental change for preventing asthma
Environmental enrichment for schizophrenia
Enzyme replacement and substrate reduction therapy for Gaucher disease
Enzyme replacement therapy for Anderson-Fabry disease
Enzyme replacement therapy for trimethylaminuria (odour problems)
Enzyme replacement therapy with galsulfase for mucopolysaccharidosis type VI
Enzyme replacement therapy with idursulfase for mucopolysaccharidosis type II (Hunter syndrome)
Enzyme replacement therapy with laronidase (Aldurazyme?) for treating mucopolysaccharidosis type I
Ephedrine for myasthenia gravis
Ephedrine for shortening the time to achieve excellent intubation conditions during direct laryngoscopy in adults
Epidermal growth factor receptor blockers for the treatment of ovarian cancer
Epidermal growth factor receptor targeted therapy in locally advanced head and neck squamous cell carcinoma
Epidural analgesia for cardiac surgery
Epidural blood patching for preventing and treating post–dural puncture headache
Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery
Epidural versus non-epidural or no analgesia in labour
Epinephrine for the resuscitation of apparently stillborn or extremely bradycardic newborn infants
Epiretinal brachytherapy for wet age-related macular degeneration (AMD)
Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis
Ergonomic design and training for preventing work-related musculoskeletal disorders of the upper limb and neck in adults
Ergonomic interventions for preventing musculoskeletal disorders in dental care practitioners
Ergonomic positioning or equipment for treating carpal tunnel syndrome
Eribulin with vinorelbine for the treatment of locally advanced or metastatic breast cancer
ER-Yag laser plus topical 5-fluorouracil preceding narrow band UVB phototherapy for repigmentation in vitiligo
Erythropoiesis stimulating agents for anaemia in adults with chronic kidney disease: a network meta-analysis
Erythropoiesis-stimulating agents for anemia in rheumatoid arthritis
Erythropoiesis-stimulating agents for myelodysplastic syndromes
Erythropoietin and Darbepoetin for patients with malignant disease
Erythropoietin for minimising perioperative allogeneic blood transfusion in cardiac surgery
Erythropoietin for preterm infants with hypoxic ischaemic encephalopathy
Erythropoietin or darbepoetin for patients with cancer
Escitalopram versus other antidepressive agents for depression
Eslicarbazepine acetate add-on for drug-resistant partial epilepsy
Eszopiclone for insomnia
Etanercept for the treatment of rheumatoid arthritis
Ethanol locks to prevent catheter-related bloodstream infections in paediatric patients with intestinal failure undergoing parenteral nutrition
Ethnically specific and specialist services for people with schizophrenia
Etidronate and risk of upper gastrointestinal injury in osteoporotic fractures
Evening Primrose oil for schizophrenia
Evening versus morning dosing regimen drug therapy for hypertension
Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia
Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia
Excitatory amino acid antagonists for acute stroke
Exclusion diets for irritable bowel syndrome
Exclusion diets for preventing atopic eczema in infants at high risk for the development of atopy
Exclusion diets for treating established atopic eczema
Exclusive breast-feeding for preventing atopic eczema in infants at high risk for the development of atopy
Exenterative surgery for recurrent gynaecological malignancies
Exenterative surgery for recurrent gynaecological malignancies
Exercise and mobilisation interventions for carpal tunnel syndrome
Exercise based rehabilitation for heart failure
Exercise for acute respiratory infections
Exercise for acutely hospitalised older medical patients
Exercise for cancer cachexia in adults
Exercise for depression
Exercise for fibromyalgia syndrome
Exercise for hemophilia
Exercise for improving cardiovascular status in rheumatoid arthritis
Exercise for improving outcomes after osteoporotic vertebral fracture
Exercise for intermittent claudication
Exercise for non-alcoholic fatty liver disease
Exercise for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Exercise for older depressed people
Exercise for osteoarthritis of the hip
Exercise for pregnant women for preventing gestational diabetes mellitus
Exercise for preventing low bone mineral density in children with juvenile rheumatoid arthritis
Exercise for reducing fear of falling in older people living in the community
Exercise for the management of ACL injuries in combination with collatoral ligament and meniscal damage
Exercise for the management of cancer-related fatigue in adults
Exercise for the management of cancer-related fatigue in adults
Exercise in depression
Exercise interventions and patient beliefs for people with chronic hip and knee pain: a mixed methods review
Exercise interventions during recovery from Lyme disease
Exercise interventions for men with prostate cancer
Exercise interventions for shoulder dysfunction in patients treated for head and neck cancer
Exercise interventions for smoking cessation
Exercise interventions for smoking cessation
Exercise interventions on health-related quality of life for cancer survivors
Exercise interventions on health-related quality of life for people with cancer during active treatment
Exercise prescriptions' as a treatment for depression
Exercise programs for people with dementia
Exercise therapy for chronic fatigue syndrome (individual patient data)
Exercise therapy for fatigue in multiple sclerosis
Exercise therapy for schizophrenia
Exercise training for adults with chronic kidney disease
Exercise training undertaken by people within 12 months of lung resection for non-small cell lung cancer
Exercise training undertaken within 12 months following lung resection for patients with non-small cell lung cancer
Exercise, orthoses and splinting for treating Achilles tendinopathy
Exercise-based cardiac rehabilitation for adults after heart valve surgery
Exercise-based cardiac rehabilitation for adults with atrial fibrillation
Exercise-based interventions for conservatively or surgically treated anterior cruciate ligament injuries in adults
Exercise-based rehabilitation for heart failure
Exercises for adolescent idiopathic scoliosis
Exercises for hand osteoarthritis
Exercises for mechanical neck disorders
Exit interviews to reduce turnover amongst healthcare professionals
Expectant care versus surgical treatment for miscarriage
Expedited versus conservative approaches for vaginal delivery in breech presentation
Experimental devices can provide electrical stimulation to potentially suppress tinnitus. Is this treatment effective?
Expert systems for fetal assessment in labour
Exposure therapy versus cognitive processing therapy for adults with PTSD for remission
Extended discussion of information for informed consent for participation in clinical trials
Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin treatment for 48 weeks in chronic hepatitis C genotype 1 infected slow-responder adult patients
External cephalic version for breech presentation at term
External counterpulsation for acute ischaemic stroke
External fixation methods for treating distal radial fractures in adults
Extra fluids for breastfeeding mothers for increasing milk production
Extracorporeal membrane oxygenation (ECMO) for acute heart failure
Extracorporeal membrane oxygenation for critically ill adults
Extracorporeal photopheresis versus alternative treatment for chronic graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients
Extracorporeal photopheresis versus standard treatment for acute graft-versus-host disease after haematopoietic stem cell transplantation in paediatric patients
Extracorporeal shock wave lithotripsy (ESWL) versus ureteroscopic management for ureteric calculi
Extracorporeal shockwave therapy (ESWT) forrefractory greater trochanteric pain syndrome
Extraction of primary (baby) teeth for unerupted palatally displaced permanent canine teeth in children
Extramedullary fixation implants and external fixators for extracapsular hip fractures in adults
Extra-urethral (non-circumferential) retropubic adjustable compression devices for stress urinary incontinence
Eye movement desensitisation and reprocessing in obsessive compulsive disorder
Face to face interventions for informing or educating parents about early childhood vaccination
Face to face interventions for informing or educating parents about early childhood vaccination
Face-down positioning or posturing after macular hole surgery
Face-to-face interventions for promoting physical activity
Face-to-face versus remote and web 2.0 interventions for promoting physical activity
Facial aesthetics: is botulinum toxin treatment effective and safe?
Facilitated self-help for the treatment of mild anxiety and depressive disorders in adults with autism
Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Factors associated with non-adherence to oral medication for inflammatory bowel disease
Factors influencing the regular use of prophylactic medication for those with asthma.
Factors that impact on the use of mechanical ventilation weaning protocols in critically ill adults and children: a qualitative evidence-synthesis
Faecal microbiota transplant for C. difficile infection
Famciclovir and other new antiviral agents for preventing postherpetic neuralgia
Family and carer smoking control programmes for reducing children's exposure to environmental tobacco smoke
Family intervention (brief) for schizophrenia
Family interventions for the families of people with schizophrenia presenting for the first time
Family therapy for depression
Family therapy for schizophrenia
Family-centred care for hospitalised children aged 0-12 years
Fast track surgery versus conventional recovery strategies for colorectal surgery
Fasting for haemostasis in children with gastrointestinal bleeding
Fast-track cardiac care for adult cardiac surgical patients
Febuxostat for treating chronic gout
Feedback or biofeedback to augment pelvic floor muscle training for urinary incontinence in women
Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and palate
Feeding interventions for improving the physical and psychosocial health of disadvantaged children aged three months to five years
Felbamate as an add-on therapy for refractory epilepsy
Femoral nerve blocks for acute postoperative pain after knee replacement surgery
Femoral nerve blocks for acute postoperative pain after knee replacement surgery
FeNO measurement in asthma management
Fenoldopam for preventing and treating acute kidney injury
Fermented milk for hypertension
Fertility awareness-based methods for contraception
Fetal and umbilical Doppler ultrasound in high-risk pregnancies
Fetal assessment methods for improving neonatal and maternal outcomes in preterm prelabour rupture of membranes
Fetal electrocardiogram (ECG) for fetal monitoring during labour
Fetal manipulation for facilitating tests of fetal wellbeing
Fetal vibroacoustic stimulation for facilitation of tests of fetal wellbeing
Fewer-than-four ports versus four ports for laparoscopic cholecystectomy
Fibrates for primary prevention of cardiovascular disease events
Fibrin glue instillation under skin flaps to prevent seroma-related morbidity following breast and axillary surgery
Fibrin-based haemostatic agents for reducing blood loss in adult liver resection
Fibrinogen concentrate in bleeding patients
Fibrinogen depleting agents for acute ischaemic stroke
Fibrinolysis with a short call to needle time rather than transferr to a centre that carries out primary percutaneous coronary intervention (PPCI) for primary PCI with a delay of up to 120 minutes for a people with with acute STEMI within 1 hour of the onset of symptoms
Fibrinolytic agents for peripheral arterial occlusion
Fibrinolytic therapy for intraventricular hemorrhage in adults
Financial arrangements for health systems in low-income countries: an overview of systematic reviews
First trimester progesterone prophylaxis to increase the live birth rate in women with unexplained recurrent miscarriages
First-line allogeneic hematopoietic stem cell transplantation of HLA-matched sibling donors compared with first-line ciclosporin and/or antithymocyte or antilymphocyte globulin for acquired severe aplastic anemia
First-line beta-blockers versus other antihypertensive medications for chronic type B aortic dissection
First-line beta-blockers versus other anti-hypertensive medications for chronic type B aortic dissections
First-line chemotherapy in low-risk gestational trophoblastic neoplasia
First-line docetaxel chemotherapy for castrate-resistant prostate cancer
First-line tandem high-dose chemotherapy and autologous stem cell transplantation versus single high-dose chemotherapy and autologous stem cell transplantation in multiple myeloma, a systematic review of controlled studies
First-line treatment of advanced epidermal growth factor receptor (EGFR) mutation positive non-squamous non-small cell lung cancer
First-rank symptoms for schizophrenia
Fish oil for schizophrenia
Fish oil supplementation for psoriasis
Fish oil supplements for rheumatoid arthritis
Fish oil supplements for the prevention and treatment of hypertension in adults
Fixed courses of antibiotics versus continuing until all symptoms are resolved in Lyme disease
Fixed-dose combination therapy for the prevention of cardiovascular disease
Fixed-dose combination therapy for the prevention of cardiovascular disease
Fixed-dose combinations of drugs versus single drug formulations for treating pulmonary tuberculosis
Flavonoids for treating venous leg ulcers
Flexible sigmoidoscopy versus faecal occult blood testing for colorectal cancer screening in asymptomatic individuals
Flossing for the management of periodontal diseases and dental caries in adults
Flow-regulated versus differential pressure-regulated shunt valves for adult patients with normal pressure hydrocephalus
Fluid and pharmacological agents for adhesion prevention after gynaecological surgery
Fluid replacement therapy for acute episodes of pain in people with sickle cell disease
Fluid restriction and prophylactic indomethacin versus prophylactic indomethacin alone for prevention of morbidity and mortality in extremely low birth weight infants
Fluid therapy for acute bacterial meningitis
Fluids and diuretics for acute ureteric colic
Flunisolide for chronic asthma
Fluocinolone acetonide intravitreal implant for chronic diabetic macular oedema
Fluoride supplements (tablets, drops, lozenges or chewing gums) for preventing dental caries in children
Fluoride varnishes for preventing dental caries in children and adolescents
Fluorides for the prevention of early tooth decay (demineralised white lesions) during fixed brace treatment
Fluoroquinolones for treating tuberculosis (presumed drug-sensitive)
Fluoxetine for depression
Fluoxetine for multiple sclerosis
Fluoxetine versus other types of pharmacotherapy for depression
Flupenthixol decanoate (depot) for schizophrenia or other similar psychotic disorders
Flupenthixol versus placebo for schizophrenia
Fluphenazine (oral) versus atypical antipsychotics for schizophrenia
Fluphenazine (oral) versus placebo for schizophrenia
Flutamide for treatment of acne in women
Fluticasone versus HFA-beclomethasone dipropionate for chronic asthma in adults and children
Fluvoxamine for depression
Foam dressings for healing diabetic foot ulcers
Foam dressings for venous leg ulcers
Focal cryoablation for localised prostate cancer
Focal therapy using high-intensity focused ultrasound (HIFU) for localised prostate cancer
Foetal safety of nasal decongestants as second line therapy for pregnant women with allergic rhinitis
Folate Augmentation of Treatment - Evaluation for Depression: randomised controlled trial (FolATED)
Folate supplementation in patients with sickle cell disease
Folic acid and folinic acid for reducing side effects in patients receiving methotrexate for rheumatoid arthritis
Folic acid for fragile X syndrome
Folic acid supplementation during pregnancy for maternal health and pregnancy outcomes
Folic or folinic acid supplementation for preventing methotrexate-associated haematological side-effects in inflammatory disease
Follicular flushing during oocyte retrieval in assisted reproductive techniques
Follow-up after completion of oncological treatment
Follow-up for improving psychological well being for women after a miscarriage
Follow-up protocols for women with cervical cancer after primary treatment
Follow-up strategies for patients treated for non-metastatic colorectal cancer
Food fortification with calcium and vitamin D: impact on health outcomes
Food subsidies for modifying dietary behaviour
For an acute exacerbation of asthma, a patient has taken 150mg prednisolone per day for 1 week, and is now slowly being weaned off. Is there any information on acute or long term damage?
For any person with a pressure ulcer how effective is patient education in ulcer prevention in changing ulcer size and depth?
For any person with a pressure ulcer how effective is staff education in promoting ulcer healing?
For any person with a pressure ulcer, how effective are wound dressings at reducing the number dressing changes an ulcer requires?
For any person with an existing pressure ulcer how effective are wound dressings in preventing the development of pressure ulcers?
For any person with pressure ulcers how cost effective is staff education in preventing pressure ulcers?
For any person with pressure ulcers how effective is staff education in reducing the number of dressings?
For any person with pressure ulcers would changing patients? positions regularly reduce the number of dressings required?
For carers of patients at risk of pressue ulcers how effective is their involvement in understanding concordance to recommendations to prevent pressue ulcers?
For carers of people at risk of developing pressure ulcers how effective is the provision of information in preventing the development of pressure ulcers?
For electric and self-propelling wheelchair users how effective are different types of cushions at preventing pressure ulcers?
For how long should a person who has received emergency treatment for anaphylaxis be observed?
For infants born with cleft lip/palate what is the most effective care pathway for promoting mother/infant bonding?
For overweight people how effective is weight loss in preventing pressure ulcers?
For patients at risk of developing pressure ulcers how effective are Tilt-in-space wheelchairs at ulcer prevention?
For patients confined to bed, does treating with washing, surgical spirit and/or talcum powder at all pressure areas prevent the occurrence of pressure ulcers and at what frequency?
For patients with an acute painful sickle cell episode, are non-pharmacological interventions, such as massage, effective in improving their recovery from the episode?
For patients with Multiple Sclerosis and pressure ulcers how thickly should Iodosorb be applied to aid ulcer healing?
For patients with oral cancer and a clinically N0 neck undergoing surgery to the primary site, in which circumstances is it beneficial to carry out a simultaneous prophylactic neck dissection.
For patients with pressure ulcers how effective is the use of artificial muscle and skin to treat pressure ulcers?
For patients with pressure ulcers how effective is their involvement in understanding the value of concordance to recommendations like turning regimes, diet and fluids to improve ulcer healing?
For patients with pressure ulcers what is the most effective non addictive pain relief?
For patients with reduced mobility due to Multiple sclerosis or Spinal Injury and loss of subcutaneous tissue across their buttocks, which static wheelchair cushion is most effective at preventing pressure ulcers?
For people at risk of developing a pressure ulcer how effective are the types of beds or mattresses used to prevent ulcers in reducing ulcer-related pain?
For people at risk of developing pressure ulcers how effective is education for lay carers in prevention of pressure ulcers including signs to look for if a pressure ulcer begins to develop?
For people at risk of developing pressure ulcers what is the effectiveness of electrotherapy to develop muscle in potential pressure areas to prevent ulcers?
For people at risk of developing pressure ulcers, how effective is reconstructive surgery to restore body fat in the prevention of pressure ulcers?
For people at risk of heel pressure ulcers how effective are different heel protectors at preventing pressure ulcers?
For people at risk of heel ulcers [including those with lymphedema], how effective are specialist boot and shoe design and fitting at preventing pressure ulcers?
For people at risk of pressure ulceration in hospital, how effective is increased mobilisation (e.g.,spending less time in bed), in preventing pressure ulcers?
For people at risk of pressure ulcers and living at home, how effective would an increase be in frequency of home visits at reducing pressure ulcer incidence?
For people at risk of pressure ulcers at home reliant on lay carers, what is the most effective and carer-friendly turning schedule for preventing pressure ulcers?
For people at risk of pressure ulcers does access to a specialist service improve pressure ulcer prevention?
For people at risk of pressure ulcers how effective are methods for patients to check own skin in preventing pressure ulcers?
For people at risk of pressure ulcers how effective are pressure ulcer grading systems in determining the amount of skin damage and does the use of such scales improve ulcer healing?
For people at risk of pressure ulcers with mobility impairment, how effective are drugs for pain relief at preventing pressure ulcers through increased mobility?
For people at risk of pressure ulcers, does proper bed making help reduce pressure ulcers?
For people at risk of pressure ulcers, what is the best rating scale for assessing Pressure ulcer risk?
For people at risk of pressure ulcers, what is the impact of patient-focused education on the prevention of pressure ulcers?
For people in care homes how effective is having a wound care champion in reducing pressure ulcers?
For people in hospital at risk of developing pressure ulcers is the current organisation of nursing care effective as best practice in the prevention of pressure ulcers?
For people reliant on wheelchairs, which footplate design is best for minimising risk of pressure ulcers?
For people sitting on a pressure ulcer are pressure relieving cushions an effective alternative to bed rest?
For people using adult mental health services, how is compulsory treatment and 'control and restraint' used in different settings and what is the impact on the service user?
For people who are bed bound as a result of pressure ulcers, does support and bed coaching aid recovery from pressure ulcers?
For people who are incontinent and at risk of pressure ulcers, do cheap incontinence pads cause more irritation compared to expensive pads?
For people who are reliant on wheelchairs how effective is repositioning in preventing pressure ulcers?
For people who have experienced suspected anaphylaxis, what is the effect on health-related quality of life of referral to specialist allergy services and provision of adrenaline injectors?
For people with a bony ischial tuberosity, is it effective to operate to make it flatter in order to prevent a pressure ulcer?
For people with a common mental health disorder, is the use of a simple algorithm when compared with a standard clinical assessment, more clinically and cost effective?
For people with a spinal injury and pressure ulcers how effective is keeping active in promoting ulcer healing?
For people with an existing pressure ulcer how effective are drugs for pain relief?
For people with an existing pressure ulcer how effective is staff education in preventing ulcer related infection?
For people with blister pressure ulcers is it more effective to remove the serum?
For people with both anxiety and depression, which disorder should be treated first to improve their outcomes?
For people with contracted limbs, how effective are standard prevention techniques and equipment?
For people with heel pressure ulcers is it more effective to support the leg compared to not supporting the leg to aid ulcer healing?
For people with impaired sensation and incontinence at risk of developing pressure ulcers, how effective are barriers creams (including Conotrane) in preventing pressure ulcers?
For people with limited memory as well as limited mobility would a prompt of routine tool which reminds people to reposition themselves help to heal pressure ulcers?
For people with Multiple Sclerosis and pressure ulcers is posture important in relation to healing?
For people with Multiple Sclerosis and pressure ulcers that won't heal, what is the best type of surgical referral?
For people with Multiple Sclerosis , how appropriate and effective is standard pressure relieving equipment?
For people with Multiple Sclerosis and pressure ulcers how effective is larval therapy in promoting ulcer healing?
For people with Multiple Sclerosis at risk of developing pressure ulcers what is the type of bed or mattresses that represents value for money to the NHS?
For people with Multiple Sclerosis at risk of pressure ulcers how effective is improving hydration in the prevention of pressure ulcers?
For people with Multiple Sclerosis living at home and at risk of developing pressure ulcers, what is the most effective prevention programme for the rigorously independent who don?t like people intervening on them?
For people with multiple sclerosis or spinal injury is working with specialist clinicians more effective in preventing pressure ulcers than working with generalists?
For people with paraplegia and a history of developing severe pressure ulcers, would regular check-ups be effective in preventing further ulcer damage?
For people with paraplegia how effective is electrical stimulation for improving muscle tone in pressure areas at prevention of pressure ulcers?
For people with persistent natal cleft splits how effective is allowing patients to sit in a chair in preventing the development of pressure ulcers?
For people with pressure ulcers and Multiple Sclerosis is bed rest detrimental to mental health?
For people with pressure ulcers and Multiple Sclerosis who have been advised to keep moving, is bed rest to treat pressure ulcers safe?
For people with pressure ulcers does smoking affect ulcer healing?
For people with pressure ulcers how effective are Allevyn standard dressings compared to Allevyn silver dressings in reducing odour?
For people with pressure ulcers how effective are drugs for pain relief in undertaking normal activities?
For people with pressure ulcers how effective are surgical operations to close ulcers in ulcer healing?
For people with pressure ulcers how effective iodine in ulcer healing?
For people with pressure ulcers how effective is direct oxygen therapy to wounds in promoting ulcer healing?
For people with pressure ulcers how effective is electro-magnetic energy in promoting ulcer healing?
For people with pressure ulcers how effective is staff education in reducing ulcer related odour?
For people with pressure ulcers is it more effective to expose the ulcer to the air/allow a fan to blow on it compared to the application of dressings to aid ulcer healing?
For people with pressure ulcers is it more effective to keep ulcers moist compared to dry?
For people with pressure ulcers using pressure relieving mattresses how effective is turning compared to not turning patients in ulcer healing?
For people with pressure ulcers what is the best way of managing wounds to reduce the frequency of changing dressings
For people with pressure ulcers what is the impact of honey-based treatments on the speed of healing and wound granulation?
For people with pressure ulcers who are wheelchair users, do pressure bandages help to heal foot sores?
For people with pressure ulcers who require a carer to help them move, what is the most effective means of repositioning patients
For people with Spina Bifida and pressure ulcers how effective are surgical operations to close pressure ulcers and reduce ulcer related infection?
For people with Spina Bifida and pressure ulcers how effective are surgical operations to cure osteomyelitis to promote ulcer healing?
For people with spinal injuries and foot ulcers what is the most effective means of increasing blood circulation to the feet to promote ulcer healing?
For people with spinal injuries and pressure ulcers how effective is keeping feet elevated in promoting ulcer healing?
For people with spinal injuries at risk of developing pressure ulcers, what is the most effective means of minimising risk of pressure ulcers on long car journeys?
For people with spinal injury and incontinence and pressure ulcers what is the effect of continuing to sit on a pressure ulcer on the speed of ulcer healing?
For people with spinal injury at risk of developing pressure ulcers how important is the knowledge and attitude of tissue viability nurses of patients' special needs in ulcer healing?
For schoolchildren with pressure ulcers who are wheelchair users, how does advice to lie face down for most of the day impact on quality of life?
For schoolchildren with pressure ulcers who are wheelchair users, is advice to lie face down for most of the day effective in promoting healing?
For those with pressure ulcers, does access to a specialist service improve pressure ulcer healing outcomes?
For those with spinal injury, to what extent is pressure ulceration prevented by good management of urinary and fecal incontinence?
For underweight people at risk of developing pressure ulcers, how effective is weight gain in preventing pressure ulcers?
For wheelchair users at risk of developing pressure ulcers does exercise (sports, or an ability to walk short distances) help improve circulation and help prevent pressure ulcers?
For wheelchair users at risk of developing pressure ulcers, how effective are transfer boards at preventing pressure ulcers?
For wheelchair users at risk of developing pressure ulcers, what is the most effective method of pressure mapping to assess pressure areas at risk to prevent the development of pressure ulcers?
For wheelchair users how effective are periods of bed rest in preventing pressure ulcers?
For wheelchair users how effective is wheelchair design in preventing pressure ulcers?
For wheelchair users sitting on a pressure ulcer how effective is bed in promoting pressure ulcer in ulcer healing?
For wheelchair users sitting on a pressure ulcer, how effective is bed rest in promoting pressure ulcer healing?
For wheelchair users with pressure ulcers, how effective is bed rest in promoting ulcer healing?
For wheelchair userswith Multiple Sclerosis at risk of pressure ulcers and with oedema what is the best way of preventing pressure ulcers on calves?
For women with a high risk pregnancy, does taking marine oil supplements prolong gestation?
For women with high blood pressure during pregnancy, what are the benefits and risks of rest in hospital compared with rest at home?
For women with high blood pressure during pregnancy, what are the short and long term effects of antihypertensive drugs for both the mother and the child?
For women with normal blood pressure during pregnancy, does rest help prevent pre-eclampsia and its complications?
For women with pre-eclampsia complicated by HELLP (Haemolysis, Elevated Liver enzymes, and Low Platelets) syndrome, is treatment with steroids beneficial?
For women with pre-eclampsia, does Chinese herbal medicine prevent complications, and is it safe?
For women with raised blood pressure during pregnancy, at what level of blood pressure does antihypertensive medication become worthwhile?
For women with raised blood pressure during pregnancy, what are the advantages and disadvantages of wearing a device to measure blood pressure over a period of time, usually 24 hours, compared to conventional measuring of blood pressure in clinic?
For women with troublesome fibroids who wish to retain or enhance their fertility, is myomectomy or embolisation better?
Formal education of patients about to undergo laparoscopic cholecystectomy
Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma
Formula versus donor breast milk for feeding preterm or low birth weight infants
Fortification of maize flour with iron for preventing anaemia and iron deficiency in populations
Fortification of staple foods with vitamin A for preventing vitamin A deficiency
Fortification of staple foods with zinc for improving zinc status and other health outcomes in the general population
Fortifying food with calcium during pregnancy, rather than taking calcium tablets to prevent pre-eclampsia.
Fractional exhaled nitric oxide in guiding inhaled corticosteroid dosing through stepping-up and stepping-down protocols in asthma management
Fractional exhaled nitric oxide testing in diagnosing asthma
Framing of health information messages
Frenotomy for tongue-tie in newborn infants
Frequency modulation (FM) system in auditory processing disorder
Frequency of administration of erythropoiesis-stimulating agents for the anaemia of end-stage kidney disease in dialysis patients
Fresh frozen femoral head allograft compared to processed femoral head allograft in revision hip arthroplasty
Fresh versus frozen embryo transfers for assisted reproduction
FSH replaced by low-dose hCG in the late follicular phase versus continued FSH for assisted reproductive techniques
FSH replaced by low-dose hCG in the late follicular phase versus FSH alone for assisted reproductive techniques
Functional analysis-based interventions for challenging behaviour in dementia
Functional electrical stimulation (FES) versus conventional aerobic exercise (CA) in chronic heart failure (CHF) patients
Functional endoscopic balloon dilation of sinus ostia for chronic rhinosinusitis
Functional endoscopic sinus surgery for chronic rhinosinusitis
Fundoplication versus postoperative medication for gastro-oesophageal reflux in children with neurological impairment undergoing gastrostomy
Furosemide for transient tachypnoea of the newborn
Fusion versus conservative management for low-grade isthmic spondylolisthesis
Gabapentin add-on for drug-resistant partial epilepsy
Gabapentin augmentation for obsessive compulsive disorder
Gabapentin for chronic neuropathic pain and fibromyalgia in adults
Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults
Galantamine for vascular cognitive impairment
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke
Gamma nail or sliding hip screw for the treatment of intertrochanteric fracture
Gangliosides for the treatment of diabetic peripheral neuropathy
Ganoderma lucidum (Reishi mushroom) for cancer treatment
Garlic for diabetes mellitus
Garlic for peripheral arterial occlusive disease
Garlic for the common cold
Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients
Garlic, or garlic preparations, to prevent pre-eclampsia and its complications.
Gases for establishing pneumoperitoneum during laparoscopic abdominal surgery
Gastrostomy feeding versus oral feeding alone for children with cerebral palsy
Gemcitabine for unresectable, locally advanced or metastatic bladder cancer
Gene therapy for haemophilia
Gene therapy for sickle cell disease
General health checks in adults for reducing morbidity and mortality from disease
General physical health advice for people with serious mental illness
Genetic testing before anticoagulation
Genetic testing for prevention of severe drug-induced skin rash
Genital ulcer disease treatment for reducing sexual acquisition of HIV
Gentamicin-impregnated collagen implants for the reduction of surgical site infections
Ginkgo biloba extract for age-related macular degeneration
Ginkgo biloba for intermittent claudication
Ginkgo biloba for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Ginkgo biloba for tinnitus
Ginkgo special extract EGb 761® for vertigo
Ginseng for cognition
Ginseng for improving the quality of life in people with cancer
Gloves, extra gloves or special types of gloves for preventing percutaneous exposure injuries in healthcare personnel
Glucagon-like peptide analogues for type 2 diabetes mellitus
Glucocorticoid with cyclophosphamide for paraquat-induced lung fibrosis
Glucocorticoids for acute viral bronchiolitis in infants and young children
Glucocorticoids for decompensated heart failure
Glucocorticoids for the treatment of anaphylaxis
Glucocorticosteroids for alcoholic hepatitis
Glucocorticosteroids for primary sclerosing cholangitis
Glucose for the management of procedural pain in neonates
Glucose lowering therapies for chronic kidney disease and kidney transplantation
Glucose targets for preventing diabetic kidney disease and its progression
Glutamine supplementation for critically ill adults
Glutamine supplementation for young infants with severe gastrointestinal disease
Glutamine supplementation to prevent morbidity and mortality in preterm infants
Glycaemic control for patients with acute coronary syndrome
Glycerin laxatives for prevention or treatment of feeding intolerance in very low birth weight infants
Glycoprotein IIb-IIIa inhibitors for acute ischaemic stroke
Glycopyrronium bromide for chronic obstructive pulmonary disease
GnRH agonists or OCPs for symptom relief in women with endometriosis-associated pain
Goal-directed fluid management for reduction of gastrointestinal complications in adults undergoing major abdominal surgery
Gonadotrophin-releasing hormone agonist protocols for pituitary suppression in assisted reproduction
Gonadotrophin-releasing hormone analogues for pain associated with endometriosis
Gonadotrophins for idiopathic male factor subfertility
Gonadotrophins for ovulation induction in women with polycystic ovarian syndrome
Governance arrangements for health systems in low-income countries: an overview of systematic reviews
GP-led melanoma follow up for improved patient satisfaction
Granulocyte colony stimulating factor therapy for acute myocardial infarction
Granulocyte-colony stimulating factor for acute liver failure or acute-on-chronic liver failure
Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections
Granulopoiesis-stimulating factors for preventing infections after autologous peripheral stem cell transplantation for lymphoma and multiple myeloma in adults
Green and black tea for the primary prevention of cardiovascular disease
Green tea for the prevention of gastrointestinal cancer
Green tea for weight loss and weight maintenance in overweight or obese adults
Group medical appointments for people with physical illness
Group versus conventional antenatal care for women
Group-based parent training programmes for improving parental psychosocial health
Growth hormone for in vitro fertilization
Growth monitoring and promotion (GMP) for children in low and middle income countries
Guanylate cyclase stimulators for pulmonary hypertension
Guidewire-assisted cannulation of the common bile duct for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis
Habit retraining in the management of urinary incontinence
Haematological interventions for treating disseminated intravascular coagulation during pregnancy and postpartum
Haemodialysis duration, frequency and intensity for end-stage kidney disease
Haemodilution for acute ischaemic stroke
Haemodilution for retinal vein occlusion
Haemodilution to decrease blood loss and blood transfusion requirements for liver resection
Haemoglobin target in the treatment of anaemia associated with Chronic Kidney Disease
Haemophilus influenzae oral vaccination for preventing acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease
Haemostatic drugs for traumatic brain injury
Haloperidol dose for the acute phase of schizophrenia
Haloperidol for long-term aggression in psychosis
Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation)
Haloperidol versus chlorpromazine for schizophrenia
Haloperidol versus first generation antipsychotics for schizophrenia
Haloperidol versus low-potency first-generation antipsychotic drugs for schizophrenia
Haloperidol versus placebo for schizophrenia
Hand allotransplantation
Harmonic scalpel versus other surgical procedures for tonsillectomy
Has the adoption of target times for prostate cancer referrals and treatment had a beneficial effect on outcomes?
Has the FAST (Face-Arm-Speech-Time to call) campaign improved stroke management?
Has the National Stroke Strategy impacted on the provision of services for patients with dysphagia?
Has the National Stroke Strategy impacted on the provision of services for patients with long term communication problems following stroke?
Head massage for tinnitus
Health checks for people with intellectual disabilities to reduce morbidity and premature mortality
Health system and community level interventions for improving antenatal care coverage and health outcomes
Health, not weight loss, focused programmes versus conventional weight loss programmes for cardiovascular risk factors
Healthcare financing systems for increasing the use of tobacco dependence treatment
Heat therapies for acne
Heated, humidified air for the common cold
Heavy metal chelation for Lyme disease
Helicobacter pylori eradication for Parkinson's disease
Helicopter emergency medical services for adults with major trauma
Heliox for croup in children
Helminth therapy (worms) for allergic rhinitis
Helminth therapy (worms) for induction of remission in inflammatory bowel disease
Hematopoietic stem cell transplantation for Gaucher disease
Hematopoietic stem cell transplantation for people with ?-thalassaemia major
Hematopoietic stem cell transplantation for people with sickle cell disease
Hemodilution to improve visual acuity in branch retinal vein occlusion
Hemodilution to improve visual acuity in central retinal vein occlusion
Heparin and related substances for preventing diabetic kidney disease
Heparin and related substances for treating diabetic foot ulcers
Heparin for assisted reproduction
Heparin for the prevention of venous thromboembolism in acutely ill medical patients (excluding stroke and myocardial infarction)
Heparin versus 0.9% sodium chloride intermittent flushing for the prevention of occlusion in long term central venous catheters in infants and children
Heparin versus normal saline for patency of arterial lines
Heparin versus placebo for non-ST elevation acute coronary syndromes
Heparin-bonded catheters for prolonging the patency of central venous catheters in children
Hepatic late adverse effects after antineoplastic treatment for childhood cancer
Hepatic lymph nodes during resection of liver metastases from colorectal cancer
Hepatitis A immunisation in persons not previously exposed to hepatitis A
Hepatitis B immune globulin for preventing hepatitis B recurrence after liver transplantation
Hepatitis B vaccination during pregnancy for preventing infant infection
Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection
Hepatotoxic effects of acetaminophen in alcoholics when taken for more than a few days
Herbal and dietary therapies for primary and secondary dysmenorrhoea
Herbal interventions for allergic rhinitis
Herbal interventions for chronic asthma in adults and children
Herbal medications for Ménière's disease
Herbal medicinal products or preparations for neuropathic pain and fibromyalgia
Herbal medicines for advanced colorectal cancer
Herbal medicines for fatty liver diseases
Herbal medicines for the treatment of inflammatory bowel disease
Herbal medicines for the treatment of rhinosinusitis
Herbal medicines for viral myocarditis
Herbal preparations for uterine fibroids
Herbal remedies (including cannabis and cannabinoids) for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Herbal therapy for treating rheumatoid arthritis
High altitude therapy for asthma
High dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with early poor prognosis breast cancer
High dose chemotherapy and autologous bone marrow or stem cell transplantation versus conventional chemotherapy for women with metastatic breast cancer
High dose versus low dose oxytocin for augmentation of delayed labour
High dose versus standard dose proton pump inhibitor for short term management of erosive reflux oesophagitis
High flow nasal cannula for respiratory support in preterm infants
High flow nasal cannula for respiratory support in term infants
High flow nasal cannulae for respiratory support in adult intensive care patients
High frequency jet ventilation versus high frequency oscillatory ventilation for pulmonary dysfunction in preterm infants
High initial concentration versus low initial concentration sevoflurane for inhalational induction of anaesthesia
High versus low positive end-expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute lung injury and acute respiratory distress syndrome
High-carbohydrate, high-protein, low-fat versus low-carbohydrate, high-protein, high-fat enteral feeds for burns
High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma
High-dose chemotherapy followed by autologous stem cell transplantation for patients with relapsed/refractory Hodgkin lymphoma
High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma
High-dose dual therapy of omeprazole and amoxycillin for Helicobacter pylori eradication in patients with gastric MALT lymphoma
High-dose therapy with autologous stem cell transplantation versus chemotherapy or immuno-chemotherapy for follicular lymphoma in adults
High-dose versus low-dose oxytocin for augmentation of delayed labour
High-dose versus non-high-dose proton pump inhibitors for bleeding peptic ulcers in seriously ill patients
Higher versus lower oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth
Higher versus lower protein intake in formula-fed low birth weight infants
High-flow nasal cannula therapy for infants with bronchiolitis
High-flow nasal cannula therapy for respiratory support in children
High-flux versus low-flux membranes for end-stage kidney disease
High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome
High-intensity focused ultrasound (HIFU) for atrial fibrillation
High-intensity versus low-intensity physical activity or exercise in patients with hip or knee osteoarthritis
High-volume haemofiltration for sepsis
Hip protectors for preventing hip fractures in elderly nursing home residents
Hip protectors for preventing hip fractures in older people
Hip resurfacing versus traditional total hip arthroplasty for osteoarthritis and other non-traumatic diseases of the hip
Histamine H2-receptor antagonists for urticaria
Histamine type 2 receptor antagonists as adjuvant treatment for resected colorectal cancer
Histologic scoring indices for evaluation of disease activity in ulcerative colitis
HMG CoA reductase inhibitors (statins) for dialysis patients
HMG CoA reductase inhibitors (statins) for kidney transplant recipients
HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis
HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass
Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma
Holding chambers versus nebulisers for inhaled drugs in chronic asthma
Holding chambers versus nebulisers for inhaled steroids in chronic asthma
Home care by outreach nursing for chronic obstructive pulmonary disease
Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age
Home- or community-based programmes for treating malaria
Home safety education and provision of safety equipment for injury prevention
Home uterine monitoring for detecting preterm labour
Home versus hospital glucose monitoring for gestational diabetes during pregnancy
Home versus hospital intravenous antibiotic therapy for cystic fibrosis
Home versus hospital-based intravenous antibiotic treatment for Lyme disease
Home- versus hospital-based phototherapy for the treatment of non-haemolytic jaundice in infants at more than 37 weeks' gestation
Home versus hospital-based phototherapy for the treatment of non-haemolytic jaundice in infants more than 37 weeks gestation
Home visits during pregnancy and after birth for women with an alcohol or drug problem
Home-based antipyretic use for parental distress caused by fever
Home-based child development interventions for preschool children from socially disadvantaged families
Home-based educational interventions for children with asthma
Home-based exercise programmes for intermittent claudication
Home-based physiotherapy interventions to reduce breathlessness during activities of daily living in severe COPD
Home-based therapy programmes for upper limb functional recovery following stroke
Home-care 're-ablement' services for maintaining and improving older adults' functional independence
Homeopathic Oscillococcinum for preventing and treating influenza and influenza-like illness
Homeopathic remedies for migraine and osteoarthritis
Homeopathy for asthma
Homeopathy for atopic eczema
Homeopathy for Lyme disease
Homeopathy for Ménière's disease
Homeopathy for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Homeopathy for treatment of irritable bowel syndrome
Homeopathy in the treatment of allergic rhinitis
Home-use whitening toothpastes for whitening teeth in adults
Homework, organisation, and planning skills (HOPS) for school children with attention deficit-hyperactivity disorder (ADHD)
Homocysteine lowering interventions for peripheral arterial disease and bypass grafts
Honey and lozenges for children with non-specific cough
Honey as a topical treatment for wounds
Honey for acute cough in children
Hormonal and intrauterine methods for contraception for women aged 25 years and younger
Hormonal contraception for women exposed to HIV infection
Hormonal contraception for women exposed to HIV infection
Hormonal contraceptives for contraception in overweight or obese women
Hormonal therapy in advanced or recurrent endometrial cancer
Hormonal versus non-hormonal contraceptives in women with diabetes mellitus type 1 and 2
Hormone replacement for osteoporosis in women with primary biliary cirrhosis
Hormone replacement therapy (HRT) following bilateral oophorectomy with or without hysterectomy in women with symptoms of endometriosis
Hormone replacement therapy for women with type 1 diabetes mellitus
Hormone therapy for preventing cardiovascular disease in post-menopausal women
Hormone therapy for sexual function in perimenopausal and postmenopausal women
Hormone therapy in postmenopausal women and risk of endometrial hyperplasia
Horse chestnut seed extract for chronic venous insufficiency
Horticultural therapy for schizophrenia
Hospital at home for acute exacerbations of chronic obstructive pulmonary disease
Hospital at home: home-based end of life care
Hospital nurse staffing models and patient and staff-related outcomes
House dust mite control measures to control asthma symptoms
Household interventions for preventing domestic lead exposure in children
Housing improvements for health and associated socio-economic outcomes
How accurate is positron emission tomography/computed tomography for identifying residual tumours in adults with testicular germ cell tumours?
How accurate is the Gleason system as a mechanism for grading prostate cancer?
How and at what age should people be tested if there is glaucoma in the family?
How and when can multi-disciplinary teams best advise and provide standard treatments for people with multiple sclerosis?
How and when should immunosuppression in kidney transplant patients be reduced?
How beneficial is surgery for cervical radiculopathy and myelopathy?
How best to diagnose urinary tract infection in preschool children in primary care?
How best to prepare people with diabetes for use of an insulin pump
How best to prevent pressure ulcers in people with neurological conditions?
How big a problem is non-alcoholic fatty liver disease?
How can IVF treatment be used to prevent the next generation from retinitis pigmentosa?
How can the vitreous be repaired or regenerated?
How can a defective retina be treated in people with myopic deterioration?
How can a more accurate early diagnosis of multiple sclerosis be achieved?
How can a sense of male identify be restored following stroke?
How can age related macular degeneration (AMD) be prevented?
How can an accurate eye examination be achieved for people with dementia?
How can astigmatism be diagnosed?
How can astigmatism be prevented?
How can awareness of and prevention of hypoglycaemia in type 1 diabetes be improved?
How can behaviour changes best be addressed after stroke?
How can better interventions be developed that are effective in treating vitreous opacities/eye floaters?
How can biomechanics help in support of glaucoma treatment?
How can bleeding from capillaries within the eyes be prevented for people with diabetic eye disease?
How can brief advice be tailored to have the greatest impact on specific groups?
How can carers be helped to communicate with someone with aphasia following a stroke?
How can case-finding for hepatitis B and C be improved?
How can cataract progression be slowed down?
How can cataract surgery outcome be improved?
How can cerebral visual impairment be identified, prevented and treated in children?
How can compliance in hearing aid usage be improved?
How can computer programmes be used to identify specific patient problems following stroke and strategies to deal with these problems?
How can contact lens intolerance be prevented in people with keratoconus who wear rigid gas permeable (RGP) contact lenses long term?
How can electronic devices improve or restore vision for people with optic neuropathies?
How can epiretinal membrane/fibrosis be prevented or treated?
How can exotropia be diagnosed?
How can falls among older inpatients be prevented?
How can follow-up for ocular complications be managed in patients with ocular melanoma?
How can genetic engineering be used to prevent inherited blinding eye disease retinitis pigmentosa?
How can Giant Cell Arteritis be diagnosed more easily by GPs?
How can glaucoma be prevented?
How can glaucoma be stopped from progressing?
How can glaucoma patients with a higher risk to progress rapidly be detected?
How can Growth hormone therapy help patients with retinitis pigmentosa?
How can holistic approach help Retinitis pigmentosa patients?
How can I check and detect early signs of prostate cancer myself?
How can I lose weight when taking prednisolone for asthma?
How can I manage the effects of corticosteroids, which I take for asthma, on my voice, and what effect is it having in the long term?
How can immunotherapy be used to fight metastatic ocular melanoma?
How can insulin delivery devices, such as pens, be improved to display unambiguously that insulin has been delivered?
How can insulin dosage best be adjusted around exercise and/or stress?
How can insulin dosage for type 1 diabetes best be adjusted around exercise and/or stress?
How can interventions to increase the uptake and effectiveness of stop smoking interventions in acute, maternity and mental health settings be improved?
How can interventions which have been proven effective in other countries be assessed for their cultural relevance to the UK?
How can keratoconus sufferers who are long term hard lens wearers avoid damage to the cornea as a result of the lens wearing?
How can laser technique for removing damaged tissue within the eye regenerate damaged optic nerve?
How can loss of vision be restored for people with glaucoma?
How can macular hole be prevented from developing again after surgery?
How can magnetic resonance imaging (MRI) scanning measure the progression of multiple sclerosis?
How can memory problems after stroke be improved?
How can multiple sclerosis be prevented?
How can needle and syringe programmes encourage specific groups of people who inject drugs to use the service effectively?
How can non-invasive real-time Continuous Glucose Monitoring for diabetes be achieved?
How can non-invasive, accurate, real-time Continuous Glucose Monitoring be achieved?
How can nurses help prevent urinary incontinence following a stroke?
How can optic neuritis be treated for people with Behcets disease?
How can optic neuropathies be prevented, for example anterior ischaemic optic neuropathy, Leber's hereditary optic neuropathy, optic neuritis and other optic neuropathies?
How can other eye treatments such as cataract removal affect patients with retinitis pigmentosa?
How can over-treatment for prostate cancer be prevented by identifying and excluding the treatment of harmless tumours? (Tigers & Pussycats)
How can over-treatment for prostate cancer be prevented by indentifying and excluding the treatment of harmless tumours?
How can overuse of the affected arm following a stroke best be addressed?
How can pain caused by thyroid eye disease be controlled, other than by the use of lubricants?
How can patient compliance in glaucoma be improved?
How can people identify which is the correct needle length for them when injecting insulin for diabetes?
How can people who use secondary care services (particularly mental health services), staff and visitors, best be helped to temporarily abstain from smoking while in secondary care settings?
How can people with multiple sclerosis be best supported to self manage their condition?
How can progressive multifocal leukoencephalopathy (PML) be diagnosed and treated effectively in people with multiple sclerosis?
How can pterygium be prevented, and/or treated?
How can quality of care by multiple sclerosis nurses in relation to diagnosis, treatment and prognosis of people with multiple scleros is be measured and improved?
How can reflux be treated best in babies with cleft lip/palate?
How can retinoblastoma be identified, prevented and treated in children?
How can routine use of Optical Coherence Tomography scanning and retrospective data analysis help in early glaucoma diagnosis?
How can sight loss be prevented in an individual with inherited retinal disease?
How can sight loss from diabetic retinal changes be prevented and reduced?
How can stem cells repair lamellar hole in retina for patients with retinitis pigmentosa?
How can stroke survivors and families be helped to cope with speech problems?
How can surgery be improved to repair damage caused by age-related macular degeneration?
How can surgery reduce oscillopsia caused by nystagmus?
How can the benefits of early intervention in psychosis services be maintained once service users are discharged after 3 years?
How can the best ways to care for people with dementia, including results from research findings, be effectively disseminated and implemented into care practice?
How can the brain be retrained to restore vision for people with myopia and loss of peripheral vision due to stroke?
How can the cones be re-activated for retinitis pigmentosa patients?
How can the delivery of thrombolysis be improved?
How can the development of binocular vision in young children with squint and amblyopia be promoted, and would the same approach work in older individuals without inducing intractable diplopia?
How can the effects of brain damage at birth be repaired through early intervention of stem cell treatment?
How can the effects of brain damage on vision be best ameliorated?
How can the fetus at risk of intrauterine death be identified in women with diabetes?
How can the fitting of contact lenses for people with keratoconus be improved?
How can the functional effects of surgical treatment for squint best be assessed?
How can the patient's personal account of tinnitus distress be used to construct an effective counselling strategy?
How can the rejection of corneal transplants be prevented?
How can the risk of anaesthetic induced strokes be reduced?
How can the risk of losing sight for people with retinal detachment be reduced?
How can the success rate of surgery for retinal detachment be improved?
How can the treatments for retinopathy of prematurity be improved?
How can the uptake of hepatitis C treatment be improved among all populations in primary and secondary care?
How can the use of prisms in spectacles be made more effective to help double vision caused by thyroid eye disease?
How can thyroid orbital vascular congestion (treated by surgery) be differentiated accurately from thyroid orbital inflammation (treated with immunosuppression) in the clinic?
How can tinnitus be effectively managed in people who are Deaf or who have a profound hearing loss?
How can uveitis in children be managed, to reduce the long-term risk of blindness?
How can vitreous detachment be prevented?
How can vitreous opacities/eye floaters be prevented?
How can vitreous syneresis/degenerative vitreous be prevented?
How can we better manage severe ocular surface disease in children, such as blepharokeratoconjunctivitis and vernal keratoconjunctivitis?
How can we better predict the outcome of childhood exotropia surgery?
How can we correct the genetic defects in the embryo to avoid Retinitis pigmentosa?
How can we create more comfortable lens for keratoconus correction to allow longer wear times?
How can we cure Bells Palsy?
How can we cure congenital nystagmus?
How can we cure iritis?
How can we cure key hole shaped pupil?
How can we cure myopia?
How can we cure nystagmus?
How can we cure optic neuritis?
How can we detect early signs of keratoconus?
How can we detect keratoconus in childhood?
How can we detect serious potential damage to the retina or people with diabetes be detected other than by screening photography?
How can we determine objectively the state of the ocular surface in patients with glaucoma?
How can we develop a structural test based on nerve condition that would be a good predictor of visual field loss?
How can we develop eye drops which would increase natural corneal collagen cross-linking in keratoconus?
How can we develop treatment for visual pathway damage associated with pre-term and full term birth?
How can we develop treatments for Acanthamoeba Keratitis that are non-toxic to the anterior surface?
How can we diagnose retinitis pigmentosa in people who have not developed symptoms?
How can we differentiate sight loss caused by an eye problem from sight loss caused by a brain problem for people with dementia?
How can we eliminate short sightedness genetically?
How can we eliminate the risks associated with corneal transplant?
How can we encourage tear production rather than attempting to reproduce the tear film artificially?
How can we ensure appropriate treatment for Birdshot Chorioretinopathy considering severity of disease?
How can we ensure early detection of macular degeneration, both wet and dry?
How can we ensure that better lenses (lighter, thinner, cheaper, more choices, variety, etc) are available for people with High Myopia who wear glasses?
How can we ensure the most effective diagnostics in early consultancy periods for retinitis pigmentosa patients.
How can we find a cure for Bests disease?
How can we find more effective and longer acting treatment for macular edema?
How can we find out who has a tendency to develop Keratoconus before they show signs of the condition?
How can we have laser surgery to correct astigmatism for people with nystagmus?
How can we help prevent sight loss from age related macular degeneration (AMD) after cataract surgery?
How can we help stroke patients with vision loss to see again?
How can we identify any long-term complications from anti-vascular endothelial growth factor treatment for retinopathy of prematurity?
How can we identify progression in visual detriovation other than by VFA (Visual Field Analysis) or OCT (Optical Coherence Tomography) for patients with Diabetic Retinopathy?
How can we improve early diagnosis of thyroid eye disease (TED)?
How can we improve management of glaucoma?
How can we improve muscular co-ordination between eyes for people with diplopia?
How can we improve older people's confidence about going out at night?
How can we improve patient compliance in glaucoma?
How can we improve surgical treatment for Thyroid Eye Disease (TED)?
How can we improve surgical treatment for thyroid eye disease?
How can we improve techniques for measuring the progression of glaucoma?
How can we improve the diagnosis of cleft palate?
How can we improve treatment and outcome for visual pathway damage associated with premature birth including retinopathy of prematurity?
How can we improve treatment to save eye sight from microbial keratitis?
How can we know whether someone will develop glaucoma?
How can we maintain or improve cognitive function for people with central nervous system (CNS) tumours?
How can we make doctors better aware of rare anti-epileptic drug side effects?
How can we make eye drops easier to administer?
How can we monitor our own eye pressure?
How can we prevent a herpes attack on the iris after an eye injection?
How can we prevent a slight rise in eye pressure without eye drops?
How can we prevent adult vitelliform macular dystrophy?
How can we prevent age related macular degeneration (AMD)?
How can we prevent anterior ischemic optic neuropathies?
How can we prevent autoimmune problems before orbital decompression for people with thyroid eye disease?
How can we prevent Birdshot?
How can we prevent cataract in children?
How can we prevent cataracts from developing?
How can we prevent congenital nystamus?
How can we prevent corneal grafts from rejecting?
How can we prevent corneal infections for wearers of contact lenses?
How can we prevent corneal scarring after ocular burns?
How can we prevent corneal transplant from becoming infected if patient has suffered with Herpes before?
How can we prevent damage to the nerve structure of the eye before glaucoma is diagnosed?
How can we prevent dry Age Related Macular Degeneration (AMD)?
How can we prevent exotropia?
How can we prevent eye melanoma?
How can we prevent Fuchs endothelial dystrophy?
How can we prevent glaucoma by genetically regulating excessive production of fluid in the eye?
How can we prevent Graves eye Disease?
How can we prevent hereditary glaucoma?
How can we prevent increased ocular pressure?
How can we prevent iritis?
How can we prevent keratoconus?
How can we prevent Leber's hereditary optic neuropathy?
How can we prevent microbial keratitis?
How can we prevent nystagmus?
How can we prevent or treat raised intraocular pressure resulting from the use of steroids following corneal graft surgery?
How can we prevent pseudoexfoliation glaucoma?
How can we prevent pterygium from causing a refractive error which results in blindness?
How can we prevent scarring on artificial lenses for children?
How can we prevent sensitivity to light for people with keratoconus?
How can we prevent sight loss caused by Giant Cell Arteritis (GCA)?
How can we prevent the progression of myopia?
How can we prevent thyroid eye disease (TED)?
How can we prevent trachoma?
How can we prevent uveitis?
How can we prevent wet age related macular degeneration (AMD)?
How can we promote the development of binocularity in young children with strabismus and amblyopia, and would the same approach work in older individuals without inducing intractable diplopia?
How can we reduce diagnostic delay of Hidradenitis suppurativa?
How can we reduce the incidence of corneal ectasia?
How can we restore loss of vision for people with glaucoma?
How can we restore some vision at the end stage of diabetic eye disease?
How can we reverse the damage to the eyes caused by Birdshot?
How can we screen for the early symptoms of Behcets disease?
How can we slow down progression of adult vitelliform macular dystrophy?
How can we slow down the progression of diabetic retinopathy?
How can we slow the progression of Birdshot?
How can we stop glaucoma progressing?
How can we tailor Anti-vascular endothelial growth factor (anti - VEGF) treatment to specific genetic markers predictive for the development of age related macular degeneration (AMD)?
How can we target genetic mutations in GNAQ/GNA11 and BAP1 which are the key gene mutations in ocular (uveal) melanoma?
How can we test glaucoma patients for sensitivity on preservatives in eye drops?
How can we transplant retina to give sight back to a blind/partially sighted person with myopic deterioration?
How can we treat macular degeneration patients with bleeding eye?
How can we treat the symptoms of photopsia with anything other than anti-epilepsy drugs for people with retinitis pigmentosa?
How can we use laser treatment for retinitis pigmentosa patients?
How can you prevent Low Tension Glaucoma from progressing?
How close are we to a fixed combination slow release monotherapy (preferebly topical or intravitrial biodegradable) for diabetic macular edema treatment?
How common is Hidradenitis suppurativa?
How common is relapse and treatment failure in lyme disease?
How could existing guidance on evaluating complex, population-wide interventions be most usefully adapted and applied to approaches that aim to increase rates of walking and cycling?
How critical is the timing of taking epilepsy medication?
How do anti-epileptic drugs affect personality?
How do children with visual impairment respond to training with magnifiers?
How do COX-2 selective NSAIDs compare to non-selective NSAIDs for arthritis?
How do epilepsy medications affect communication skills?
How do epilepsy medications affect the stomach in the long term?
How do I choose which insulin pen is best for me?
How do I know if the inhaled steroids my child is prescribed for their asthma are being delivered in the right dose and if their technique is adequate?
How do I know when my asthma is bad enough to seek medical treatment and who should I go to?
How do I manage my asthma symptoms during my menstrual cycle?
How do individual and local factors influence the effectiveness of specific approaches to encouraging walking or cycling?
How do people with achromatopsia who have never seen colour 'learn' what their shades of grey are in terms of colour?
How do rates of adherence differ with different complexities of treatment regimen for the management of type 2 diabetes?
How do tricyclics, duloxetine, glabapentin and pregabalin compare in their reduction of pain caused by diabetic neuropathy?
How do we achieve social and geographical equality of care in type 1 diabetes?
How do we determine fitness to drive after surgery?
How do we get to the real story from people with type 1 diabetes presenting in clinic and how can we tell when they are wanting to or needing to present as compliant?
How do we improve adherence to oral antipsychotic drugs?
How do we improve awareness of Hidradenitis suppurativa amongst healthcare professionals?
How do we improve screening and surveillance from the ante-natal period through to childhood to ensure early diagnosis of impaired vision and eye conditions?
How do we increase consent to organ donation in different ethnic groups?
How do we know which people will develop glaucoma having been diagnosed with ultra ocular high pressure?
How do we prevent blindness in glaucoma for people with low eye pressure?
How do we prevent fluid from building up in the eyes for people with glaucoma?
How do we prevent radical prostatectomy causing urinary incontinence?
How do we prevent risk of developing low pressure glaucoma?
How do we prevent sight loss from diabetic retinopathy?
How do you get children with asthma to take their medication regularly?
How do you monitor ocular pressure for people with uneven eye pressure?
How do you reduce pain for patients with dystrophic epidermolysis bullosa patients who are constipated?
How does a health professional predict the likelihood that a Patient with dry eye would benefit from regular use of tear supplements?
How does continuity of care impact on the prevention of pressure ulcers?
How does continuity of care impact on treatment of pressure ulcers?
How does diet affect Graves eye Disease?
How does drug therapy work in some people with Nystagmus?
How does HIV testing affect the subsequent sexual behaviour of black Africans living in England?
How does lidocaine exert its effect in alleviating tinnitus?
How does natural sunlight interact with other treatments for vitiligo?
How does sound therapy treatments compare in effectiveness to general stress management therapy?
How does spending time outdoors in natural light reduce the risk of myopia?
How does the degree of hearing loss impact on treatment choice?
How does the initiation and titration of long-acting insulin affect health-related quality of life in patients with type 2 diabetes?
How does the level of BCG vaccine protection against tuberculosis fall over time?
How does the wearing of spectacles (of any prescription) affect the progression of refractive error?
How does topical diclofenac compare with eltenac in osteoarthritis?
How does type of surgery and rehabilitation affect the outcome of anterior cruciate ligament injuries?
How early can proliferative retinopathy be detected in type 2 diabetes mellitus?
How early in pregnancy to start taking aspirin for women at moderate or high risk of pre-eclampsia to reduce the incidence of pre-eclampsia, IUGR and pre-term birth
How early is early to give statins for people with diabetes?
How effective are measures such as pressure relief by changing position in bed or leaning forward, at preventing pressure ulcers and should they be changed with age or weight loss?
How effective and cost effective are behaviour change interventions delivered remotely
How effective and cost effective are interventions that use varenicline for people who are using acute, maternity and mental health services?
How effective and cost effective are interventions which use either a 'total population' or 'high-risk population' approach to preventing type 2 diabetes among people from black and minority ethnic or lower socioeconomic groups?
How effective and cost effective are relapse prevention interventions aimed at people who use secondary care services who have quit smoking?
How effective and cost effective are stop smoking interventions for parents and carers of children who are using secondary care services?
How effective and cost effective are stop smoking interventions for partners of pregnant and breastfeeding women?
How effective and safe are IV immunoglobulins for eczema?
How effective and safe are antihistamines in treating eczema?
How effective and safe are dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) for osteoarthritis?
How effective and safe are short term or long term oral antibiotics for Hidradenitis suppurativa?
How effective and safe is laser treatment in correcting myopia?
How effective and safe is thymopentin for eczema?
How effective are all pressure relieving support surfaces in the prevention of pressure ulcers?
How effective are alternative or complimentary therapies for nocturia?
How effective are antibiotics for trimethylaminuria?
How effective are anti-oxidants when combined with mitochondrial stimulating cream in treating vitiligo?
How effective are anti-oxidants when combined with tablets such as phenylalanine in treating vitiligo?
How effective are bandages and splints in terms of avoiding sindactylia in patients with dystrophic epidermolysis bullosa?
How effective are barrier creams or sprays (for example Sudocrem and Cavilon) in the prevention of pressure ulcers?
How effective are beds, mattresses and overlays in the prevention of pressure ulcers?
How effective are biologics in treating Hidradenitis suppurativa?
How effective are colonoscopic surveillance programmes in improving overall survival and cancer-related survival in people at increased risk of colorectal cancer?
How effective are contact lenses in improving quality of life and to prevent sequelae for patients with dystrophic epidermolysis bullosa?
How effective are different behavioural strategies in helping people to cut down, either in order to stop smoking or to reduce the amount they smoke?
How effective are different types of dressings in curing wounds in dystrophic epidermolysis bullosa patients?
How effective are different types of dressings in producing new skin that is more resistant to injury in patients with dystrophic epidermolysis bullosa?
How effective are digital devices that combine a sound generator with a hearing aid for tinnitus management?
How effective are dressings and zero-friction fabric products in preventing pressure ulcers?
How effective are dressings at preventing the development of pressure ulcers?
How effective are dressings in the prevention of pressure ulcers?
How effective are dressings in ulcer healing?
How effective are drug based therapies for nocturia?
How effective are eye drops and ointments to improve Quality of life and to prevent sequelae for patient with dystrophic epidermolysis bullosa?
How effective are eye drops?
How effective are heel protectors in preventing pressure ulcers?
How effective are heel protectors in preventing ulcers?
How effective are herbal remedies in treating vitiligo?
How effective are honey dressings in promoting ulcer healing?
How effective are honey-based treatments at healing pressure ulcers?
How effective are hormone therapies, including spironolactone, for Hidradenitis suppurativa?
How effective are hormones or hormone related substances that stimulate pigment cells (MSH analogues, afamelanotide) in treating vitiligo?
How effective are incontinence devices at preventing ulcers?
How effective are interventions to help people reduce the amount they smoke (without the intention of stopping)?
How effective are interventions to promote social and emotional wellbeing among, and reduce the vulnerability of, different groups of vulnerable children aged under 5 years?
How effective are interventions to reduce skin infections in the management of eczema?
How effective are intravitreal steroids or Anti-vascular endothelial growth factor (anti-VEGF) treatment for retinal vein occlusions long term?
How effective are licensed nicotine-containing products when used for more than one year?
How effective are mobilsation strategies after hip fracture in adults?
How effective are moisturizers in improving itch and preventing new wounds in patients with dystrophic epidermolysis bullosa?
How effective are non-drug, non-surgical treatments for primary dysmenorrhoea?
How effective are oral treatments that affect the immune system in treating Hidradenitis suppurativa?
How effective are other complementary therapies (e.g. aloe vera, UNANI) in treating vitiligo?
How effective are patellar taping and bracing for knee osteoarthritis?
How effective are pressure relieving cushions in the prevention of pressure ulcers?
How effective are pressure relieving mattresses in promoting ulcer healing?
How effective are pressure relieving pads/cushions in preventing pressure ulcers?
How effective are probiotics for the treatment of eczema?
How effective are prosthesis in improving quality of life after amputations in patient with dystrophic epidermolysis bullosa?
How effective are psychological therapies and peer support groups for adults with psoriasis and psoriatic arthritis?
How effective are retinoids i.e. acitretin, isotretinoin in treating Hidradenitis suppurativa?
How effective are risk calculator tools in the prevention of pressure ulcers?
How effective are SAD light boxes in treating vitiligo?
How effective are skin protectors in the treatment of Grade 2 pressure ulcers?
How effective are some common treatments for traumatic brain injury?
How effective are static flow mattresses over time?
How effective are steroid creams in treating vitiligo?
How effective are steroid tablets in treating vitiligo?
How effective are surgical interventions for overactive bladder?
How effective are surgical operations to close pressure ulcers/help them heal?
How effective are surgical operations to close pressure ulcers?
How effective are the current UK tests in detecting Lyme disease infections due to the genospecies and strains of B burgdorferi sl in the UK?
How effective are the different types of pressure relieving beds and mattresses in preventing pressure ulces and do they meet the needs of the full range of patients at risk?
How effective are topical antibacterial treatments in hastening healing, preventing infection, increasing quality of life, decreasing smell in patients with dystrophic epidermolysis bullosa?
How effective are topical antibiotics (applied to the skin) in treating Hidradenitis suppurativa?
How effective are topical antiseptics in treating Hidradenitis suppurativa?
How effective are topical skin care products and skin care regimes at preventing pressure ulcers?
How effective are topical skin care products at prevention of pressure ulcers?
How effective are wound dressings in promoting pressure ulcer healing?
How effective are wound dressings in the promotion of pressure ulcer healing?
How effective at preventing pressure ulcers is involving patients in managing their own pressure ulcers?
How effective at preventing pressure ulcers is involving patients, family
How effective at preventing pressure ulcers is the provision of written, oral, video information to patients, for example on discharge?
How effective at prevention of pressure ulcers are sleep systems for people with physical difficulties?
How effective in preventing pressure ulcers is having a wound care champion?
How effective in preventing pressure ulcers is the provision of information to patients ?
How effective is the patient's role in managing their own pressure ulcers?
How effective is a "tumour early diagnosis protocol" in patients with dystrophic epidermolysis bullosa?
How effective is a choline elimination diet for treating trimethylaminuria?
How effective is a specialist mattress compared to conventional mattress in the prevention of pressure ulcers?
How effective is a specialized feeder in preventing oral lesions in babies in patient with dystrophic epidermolysis bullosa?
How effective is a trabeculectomy?
How effective is aloe vera to hasten wound healing for patients with dystrophic epidermolysis bullosa?
How effective is ambulatory continuous blood glucose monitoring in pregnancies complicated by diabetes?
How effective is best practice in prevention in considering the range of risk from transient problem as the result of an operation to a lifetime of risk for those with spinal injury?
How effective is botox in treating Hidradenitis suppurativa?
How effective is changing positions regularly for example by turning to prevent the development of ulcers?
How effective is clinical leadership in preventing pressure ulcers in the NHS and independent sectors?
How effective is cosmetic camouflage for the management of vitiligo?
How effective is cream containing Vitamin D analogues (calcipotriol and tacalcitol) in the treatment of vitiligo?
How effective is debridement of pressure ulcers in helping them to heal?
How effective is Dose Adjustment For Normal Eating (DAFNE) in diabetes?
How effective is education for all care staff at preventing the development of pressure ulcers?
How effective is education for lay carers to promote pressure ulcer healing including understanding and concordance to recommendations?
How effective is education into the use of cosmetic camouflage for the management of vitiligo?
How effective is electronic surveillance vs. observation of hand washing to check compliance?
How effective is exoskeleton technology in the prevention of pressure ulcers?
How effective is hand physiotherapy to avoid or delay syndactilia for patients with dystrophic epidermolysis bullosa?
How effective is hormone replacement therapy (HRT) in treating vitiligo?
How effective is improving nutrition and hydration in pressure ulcer healing?
How effective is improving nutrition and hydration in preventing pressure ulcers?
How effective is improving nutrition and hydration in the prevention of pressure ulcers?
How effective is intentional rounding in the prevention of hospital acquired pressure ulcers?
How effective is it for Health Care Assistants to assess pressure ulcer risk?
How effective is laser therapy in treating vitiligo?
How effective is laser therapy when combined with creams or ointments (e.g. steroid cream) in treating vitiligo?
How effective is laser trabeculoplasty?
How effective is levamisole in treating vitiligo?
How effective is levamisole taken by mouth when combined with creams or ointments (e.g. steroid cream) in treating vitiligo?
How effective is Lucentis age-related macular degeneration?
How effective is making staff, managers or personal carers responsible for the prevention of pressure ulcers in reducing the incidence of pressure ulcers?
How effective is melagenina in treating vitiligo?
How effective is metformin in treating Hidradenitis suppurativa?
How effective is micropigmentation in treating vitiligo?
How effective is natural sunlight in achieving repigmentation of the skin in patients with vitiligo?
How effective is negative pressure wound therapy as a treatment for pressure ulcers?
How effective is negative pressure wound therapy in pressure ulcer healing?
How effective is nerve stimulation in treating vitiligo?
How effective is non-surgical debridement in ulcer healing, what is the most effective debridement strategy?
How effective is patient education at preventing pressure ulcers, including information on how to self treat and at what stage of disease?
How effective is patient information in improving management, self care and adherence with treatment in patients with atopic eczema?
How effective is patient information on discharge from hospital in the prevention of pressure ulcers?
How effective is piperine (black pepper) cream in treating vitiligo?
How effective is piperine taken by mouth in treating vitiligo?
How effective is plant-based catalase/dismutase in treating vitiligo?
How effective is psoralen cream/ointment combined with exposure to natural sunlight (topical PUVAsol) in treating vitiligo?
How effective is psychosocial care for people with diabetes?
How effective is PUVA therapy in treating vitiligo?
How effective is PUVA therapy when combined with other creams and ointments in treating vitiligo?
How effective is PUVA therapy when combined with other medicines taken by mouth in treating vitiligo?
How effective is radiotherapy in localised versus widespread Post Transplant Lymphoproliferative Disorders?
How effective is regular turning of patients in bed at preventing pressure ulcers?
How effective is repositioning in the prevention of pressure ulcers
How effective is repositioning in the prevention of ulcers?
How effective is skin grafting in treating vitiligo?
How effective is specialist clothing in treating eczema?
How effective is staff training at preventing pressure ulcers?
How effective is taking psoralen by mouth combined with exposure to natural sunlight (oral PUVAsol) in treating vitiligo?
How effective is the addition of occupational therapy-physiotherapy to decrease contractures, osteoporosis, disability for patients with dystrophic epidermolysis bullosa?
How effective is the addition of pressure reliving devices to decrease the appearance of new lesions for patients with dystrophic epidermolysis bullosa?
How effective is the application of moisturisers in preventing ulcers?
How effective is the application of sugar to pressure ulcers to promote ulcer healing?
How effective is the avoidance of high temperatures in preventing lesions in patients with dystrophic epidermolysis bullosa?
How effective is the introduction of foreign bodies (such as intestinal worms) in treating vitiligo?
How effective is the long term use of systemic antibiotics (chronic or pulsatile) for patients with dystrophic epidermolysis bullosa?
How effective is the role of Community Nurses or District Nurses in educating carers in the best way to prevent pressure ulcers?
How effective is the specialist training for GPs who assess and prescribe treatments for eczema, including training on when to refer to a dermatologist?
How effective is the use of adjuvant or neoadjuvant radiotherapy and chemotherapy in the treatment of non-melanoma sink cancer in patients with dystrophic epidermolysis bullosa?
How effective is the use of pureed food to decrease oral and esophageal lesions for patients with dystrophic epidermolysis bullosa?
How effective is the use of vibrating platforms to decrease contractures, osteoporosis, disability in patients with dystrophic epidermolysis bullosa?
How effective is tranexamic acid for acute gastrointestinal bleeding?
How effective is transvaginal ultrasound for the detection of congenital malformations in women with diabetes and coexisting obesity?
How effective is ultrasound in identifying potential pressure ulcers?
How effective is urinary diversion surgery for urinary incontinence for people with spina bifida?
How effective is using 72 hour blood glucose monitoring and educating individuals in the management of type 1 diabetes?
How effective is UVA light therapy in treating vitiligo?
How effective is UVA light therapy when combined with creams or ointments (e.g. khellin, lactic acid, steroid creams) in treating vitiligo?
How effective is UVA light therapy when combined with treatments taken by mouth (e.g. phenylalanine, khellin) in treating vitiligo?
How effective is UVB light therapy in treating vitiligo?
How effective is UVB light therapy when combined with creams or ointments (e.g. steroid creams) in treating vitiligo?
How effective is UVB light therapy when combined with medicines taken by mouth in treating vitiligo?
How effective is UVB light therapy when combined with the needling technique in treating vitiligo?
How effectives are oral motor exercises in order to prevent microstomia in patient with dystrophic epidermolysis bullosa?
How effects on health equity are assessed in systematic reviews of interventions
How frequently should inhaler technique assessment be performed for someone with asthma?
How frequently should people at risk of pressure ulcers change positions in order to prevent pressure ulcers?
How important is the relationship between patient and clinician (empathy) in determining the success in reducing tinnitus distress?
How is inhaler technique best assessed for someone with asthma?
How is the benefit of relaxation dependent on the skills of the professional who delivers the therapy?
How long and frequent do we need to give brief advice for it to be effective on physical activity?
How long should a course of antibiotic treatment be for acne?
How many doses of reliever can be given safely to a child showing signs of an impending asthma attack?
How many people/families need to have similar symptoms of a unidentified genetic eye condition for funding to be sought to screen for the gene and hence identify it?
How many sessions of Cognitive Behaviour Therapy are needed to provide a lasting benefit to people with tinnitus?
How many sessions of combined audiological management and psychological therapy are needed to provide a lasting benefit to people with tinnitus?
How many times can people with Graves Eye Disease have orbital decompression surgery?
How many times can you use the same syringe to inject insulin?
How might acne relapses be best treated?
How much will treating psychological distress, including depression and anxiety in adults with psoriasis and psoriatic arthritis have an effect on disease severity and flare-ups?
How much alcohol is safe to consume while taking epilepsy medication?
How much do hormonal factors affect the severity of Hidradenitis suppurativa?
How much do psychological interventions (such as counselling) help people with vitiligo?
How much does avoidance of irritants and allergens help people with eczema ?
How much does family and patient training help patients with dystrophic epidermolysis bullosa?
How much does hypnotherapy/biofeedback help patients with eczema?
How much does management in reference centers help patients with dystrophic epidermolysis bullosa?
How much does massage therapy help patients with eczema?
How much does supporting and educating (about treatments and management) patients/carers help in the treatment of eczema?
How much does temperature, weather and humidity effect people with eczema?
How much does water type (hard/soft/sea) help patients with eczema?
How much does whole body fish treatment help patients with eczema?
How much effect do normal clothing fabrics have on eczema?
How much is too much medication to use of the preventer medicine when breathing difficulty does not go away over several hours?
How much symptom relief occurs in women taking Pentoxifylline for the treatment of endometriosis?
How often is it best to turn people with pressure ulcers to prevent further damage and aid healing?
How often should blood pressure be measured in healthy pregnant women and when is the best time to do this?
How often should General Practitioners check drugs and blood pressure (BP) for someone following a stroke?
How often should someone with Marfans syndrome but no sign of the eye condition be monitored?
How often should tests be run for ongoing, chronic intermediate uveitis?
How often should treatment for age-related macular degeneration be required in younger people?
How reliable are opticians' tests in the detection of glaucoma?
How reliable is first-trimester screening for Down’s syndrome incorporating levels of pregnancy associated plasma protein (PAPP-A) in women with pre-existing diabetes?
How safe and effective is laser assisted cataract surgery?
How safe is acupuncture for knee osteoarthritis?
How safe is avastin in the treatment of age-related macular degeneration, given that it was originally formulated for the treatment of breast cancer?
How safe is it for my baby if I am breastfeeding and taking antidepressant medication?
How safe is pseudocatalase cream combined with UVB light therapy in treating vitiligo?
How safe is PUVA therapy in treating vitiligo?
How safe is skin grafting in treating vitiligo?
How safe is UVA light therapy in treating vitiligo?
How safe is UVB light therapy in treating vitiligo?
How satisfied are patients with schizophrenia with the drug they take for their illness
How should healthcare professionals balance the treatment needs of children with the involvement of parents?
How should I decide whether to nebulise again following an asthma attack, or go to hospital?
How should I manage my asthma when I have a cold?
How should I take my epilepsy medication when I have a stomach upset?
How should the process of decision-making about the choice of dialysis modality, including peritoneal dialysis, be supported?
How should the process of decision-making about the choice of dialysis modality, including peritoneal dialysis, be supported?
How should the process of decision-making about the choice of dialysis modality, including peritoneal dialysis, be supported?
How should topical therapies be used to maintain disease control for people with psoriasis?
How should we manage fear of falling in older adults living in the community?
How should you manage your epilepsy medication in new time zones?
How successful is surgery for epilepsy?
How tightly controlled do fluctuations in blood glucose levels need to be to reduce the risk of developing complications in people with type 1 diabetes?
How to avoid fever after dressing changes in patients with dystrophic epidermolysis bullosa?
How to choose the best systemic antibiotic to treat cutaneous infection in patients with dystrophic epidermolysis bullosa?
How useful are Parafracta fabrics in healing ulcers?
How useful are silver impregnated clothes to prevent infection in patients with dystrophic epidermolysis bullosa?
How useful is the sbiza bar in the treatment of amblyopia compared with other methods?
How will Government / Clinical guidelines help my brittle asthma?
How would pre-screening pregnant mother reduce the risk of congenital blindness?
HTA study of antidepressants for depression in dementia - a definitive multicentre pragmatic randomised controlled trial of clinical and cost effectiveness (HTA-SADD)
Huangqi injection for patients with chronic heart failure
Human albumin infusion for treating oedema in people with nephrotic syndrome
Human chorionic gonadotrophin (hCG) for preventing miscarriage
Human growth hormone during the active phase of intestinal adaptation in short bowel syndrome
Human papillomavirus (HPV) vaccine for individuals with HIV infection
Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions
Human recombinant activated factor VII for upper gastrointestinal bleeding in patients with liver diseases
Human recombinant protein C for severe sepsis and septic shock in adult and paediatric patients
Human resource management training of supervisors for improving health and well-being of employees
Humanistic therapies versus treatment as usual for depression
Humidification of inspired air in exercise-induced asthma
Huperzine A for mild cognitive impairment
Huperzine A for vascular dementia
Hyaluronate for temporomandibular joint disorders
Hyaluronidase for reducing perineal trauma
Hyaluronidase for reducing perineal trauma
Hybrid positron emission tomography/computerised tomography vs positron emission tomography in lung cancer
Hydralazine in infants with persistent hypoxemic respiratory failure
Hydralazine/isosorbide dinitrate for heart failure
Hydration for treatment of preterm labour
Hydrocolloid dressings for healing diabetic foot ulcers
Hydrocolloid dressings for healing venous leg ulcers
Hydrocolloid dressings for treating pressure ulcers
Hydrogel dressings for healing diabetic foot ulcers
Hydrogel dressings for treating pressure ulcers
Hydrogel dressings for venous leg ulcers
Hydromorphone for cancer pain
Hydrotherapy for asthma
Hydroxyurea for psoriasis
Hydroxyzine for generalised anxiety disorder
Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa
Hyperbaric oxygen for idiopathic sudden sensorineural hearing loss and tinnitus
Hyperbaric oxygen therapy (HBOT) for fracture healing
Hyperbaric oxygen therapy and eye disorders
Hyperbaric oxygen therapy and infertility
Hyperbaric oxygen therapy and sports injuries
Hyperbaric oxygen therapy and surgical site infection
Hyperbaric oxygen therapy and thermal burns
Hyperbaric oxygen therapy and urology
Hyperbaric oxygen therapy for acute coronary syndrome
Hyperbaric oxygen therapy for acute coronary syndrome
Hyperbaric oxygen therapy for autism spectrum disorder (ASD) in children and adults
Hyperbaric oxygen therapy for Bell's palsy
Hyperbaric oxygen therapy for blunt chest injury
Hyperbaric oxygen therapy for calciphylaxis
Hyperbaric oxygen therapy for cancers and tumour sensitisation to radiotherapy
Hyperbaric oxygen therapy for cardio-pulmonary bypass
Hyperbaric oxygen therapy for chronic hepatitis
Hyperbaric oxygen therapy for chronic wounds
Hyperbaric oxygen therapy for Crohn's disease
Hyperbaric oxygen therapy for crush injuries
Hyperbaric oxygen therapy for irradiated patients who require dental implants
Hyperbaric oxygen therapy for late radiation tissue injury
Hyperbaric oxygen therapy for malignant otitis externa
Hyperbaric oxygen therapy for multiple sclerosis
Hyperbaric oxygen therapy for osteoarthritis
Hyperbaric oxygen therapy for osteonecrosis of the mandible
Hyperbaric oxygen therapy for osteoradionecrosis
Hyperbaric oxygen therapy for other chronic wounds
Hyperbaric oxygen therapy for pain syndromes
Hyperbaric oxygen therapy for peridontitis
Hyperbaric oxygen therapy for pressure ulcers
Hyperbaric oxygen therapy for promoting fracture healing and treating fracture non-union
Hyperbaric oxygen therapy for severe anaemia
Hyperbaric oxygen therapy for skin grafts and flaps
Hyperbaric oxygen therapy for soft-tissue radionecrosis
Hyperbaric oxygen therapy for surgery
Hyperbaric oxygen therapy for the adjunctive treatment of traumatic brain injury
Hyperbaric oxygen therapy for the treatment of livedoid vasculopathy
Hyperbaric oxygen therapy for traumatic brain injury
Hyperbaric oxygen therapy for treating acute surgical and traumatic wounds
Hyperbaric oxygen therapy for treatment of necrotising soft-tissue infections
Hyperbaric oxygen therapy for vascular dementia
Hyperbaric oxygen therapy for venous ulcers
Hyperbaric oxygen therapy for wound healing
Hyperbaric oxygenation for tumour sensitisation to radiotherapy
Hyperbarix oxygen therapy for soft-tissue radionecrosis
Hyperfractionated or accelerated radiotherapy for head and neck cancer
Hypertonic saline versus other intracranial pressure-lowering agents for people with acute traumatic brain injury
Hypnosis during pregnancy, childbirth, and the postnatal period for preventing postnatal depression
Hypnosis for alleviation of anxiety in adults undergoing dental treatment
Hypnosis for induction of labour
Hypnosis for pain management during labour and childbirth
Hypnosis for people with asthma
Hypnosis for preventing preterm labour
Hypnotherapy and biofeedback therapy for atopic eczema
Hypnotherapy for Ménière's disease
Hypnotherapy for nocturnal enuresis
Hypoallergenic formula milk versus cow's milk for prevention of wheeze and asthma in children with a family history of atopy
Hypoglycaemic agents for pregnant women with polycystic ovarian syndrome
Hypothalamic-pituitary-adrenal (HPA) axis suppression after treatment with glucocorticoid therapy for childhood acute lymphoblastic leukaemia
Hypothermia for neuroprotection in adults after cardiopulmonary resuscitation
Hypothermia for neuroprotection in children after cardiopulmonary arrest
Hypothermia for traumatic head injury
Hypoventilation to decrease blood loss and blood transfusion requirements for liver resection
Hysterectomy for patients with locally advanced cervical cancer after primary radiotherapy and/or chemotherapy
Hysterectomy versus hysterectomy plus oophorectomy for premenopausal women
Hysteroscopic morcellation of uterine fibroids
Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities
I recently became very depressed when my asthma inhaler was changed to Symbicort and felt much better when I gave myself a break from this inhaler. Is there any evidence that different inhalers have different effects on mood?
I take ventolin 2 puffs QDS & becotide 200mgs 2 puffs QDS. I constantly have coughing fits sometimes leading to vomiting or nose bleeds and stress incontinence. Are these recognised side effects of these treatments?
Ibuprofen and paracetamol in combination and separately for fever in pre-school children presenting to primary care
Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth
Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants
Ibuprofen with or without an antiemetic for acute migraine headaches in adults
Idarubicin compared to other anthracyclines for treatment of newly diagnosed acute myeloid leukaemia
Identifing people who are inactive in Primary care
If a person benefiting from taking lithium for mood disorders stays on it, are adverse renal effects dose-related?
If a person has cataracts in both eyes should they be operated on at the same time?
If Central Retinal Vascular Diseases is manifest in one eye, how can we prevent the other eye from becoming affected?
If doctors cannot diagnose asthma in children under 2, what is the most appropriate treatment?
If I avoid certain chemicals in the work place/environment, will I reduce my risk of developing prostate cancer?
If I can have my own choice of insulin, and how it is delivered, will my diabetes be better controlled?
If I treat my ear wax will it impact on my tinnitus?
If long-term blue light exposure leads to retinal damage in age-related macular degeneration would, eg, the use of blue light filtering in intraocular lenses be an effective response to take?
If my child, who has asthma, is poorly but on medication, should I send him to school?
If toe nails are being cut round instead of straight, will this produce more ingrown nails?
Ileostomy or colostomy for temporary decompression of colorectal anastomosis
Illness management and recovery programme for people with severe mental illness
Image guided surgery for the resection of brain tumours
Image-guided percutaneous procedure plus metronidazole versus metronidazole alone for uncomplicated amoebic liver abscess
Image-guided versus blind glucocorticoid injection for shoulder pain
Imaging for the exclusion of pulmonary embolism in pregnancy
Imaging modalities for characterising focal pancreatic lesions
Imaging modalities for monitoring response and recurrent disease for patients with lung cancer
Imipramine for neuropathic pain and fibromyalgia in adults
Imipramine for neuropathic pain in adults
Imiquimod for anogenital warts in non-immunocompromised adults
Immediate loading with single implant crowns
Immediate restoration/loading of immediately placed single implants: is it an effective bimodal approach?
Immediate start of hormonal contraceptives for contraception
Immediate versus deferred delivery of the preterm baby with suspected fetal compromise for improving outcomes
Immediate versus delayed reconstruction following surgery for breast cancer
Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy
Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B
Immune tolerance induction for treating inhibitors in people with congenital haemophilia A or B
Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis
Immunomodulatory interventions for focal epilepsy syndromes
Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy
Immunonutrition for patients undergoing surgery for head and neck cancer
Immunonutrition in patients undergoing surgery for head and neck cancer
Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis
Immunosuppressant and immunomodulatory treatments for multifocal motor neuropathy
Immunosuppression in primary focal segmental glomerular sclerosis (FSGS) in adults
Immunosuppression in renal transplantation
Immunosuppressive drug therapy for preventing rejection following lung transplantation in cystic fibrosis
Immunosuppressive drugs for Lyme disease
Immunosuppressive or biological therapy compared with early surgery for Crohn's disease limited to the distal ileum
Immunosuppressive T-cell antibody induction for heart transplant recipients
Immunotherapy (oral and sublingual) for food allergy to fruits
Immunotherapy for diabetic amyotrophy
Immunotherapy for idiopathic lumbosacral plexopathy
Immunotherapy for IgM anti-myelin-associated glycoprotein paraprotein-associated peripheral neuropathies
Immunotherapy vs conventional asthma pharmacotherapy and allergen immunotherapy
Impact of epithelial ovarian cancer screening on patient-relevant outcomes in average-risk postmenopausal women
Impact of haemophilus influenza type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes
Impact of long-term opioid use for chronic non-cancer pain on misuse, abuse or addiction, overdose, falls and fractures
Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain
Impact of preconception counselling on quality of life and satisfaction of care in women with epilepsy
Implantable defibrillators versus medical therapy for cardiac channelopathies
Implantable miniature telescope (IMT) for vision loss due to end-stage age-related macular degeneration
Implementation of treatment guidelines for specialist mental health care
Implementation strategies for health systems in low-income countries: an overview of systematic reviews
Implementing and assessing tailored and culturally appropriate community-level interventions to prevent type 2 diabetes among people at high risk?
Importance of correct point location in acupuncture for migraine prophylaxis
Improving speed of access to specialist care for people with moderate to severe psoriasis
In a critically ill patient is dopexamine effective at preventing renal failure?
In addition to using gestational age and birth weight as screening criteria for retinopathy of prematurity, could additional factors be used to reduce the number of unnecessary screenings performed?
In adults greater than 18 years of age with suspected transient ischaemic attack is the administration of aspirin by paramedics in prehospital care safe in the absence of a brain scan?
In adults with hypertension, which drug treatment is the most clinically and cost effective for step 4antihypertensive treatment?
In adults with primary hypertension, does the use of out-of-office monitoring improve response to treatment?
In adults with stage 4 or 5 chronic kidney disease (CKD), including those on dialysis, what is the long-term effectiveness and safety of aluminium hydroxide in controlling serum phosphate?
In adults with stage 4 or 5 chronic kidney disease (CKD), including those on dialysis, what is the long-term effectiveness and safety of magnesium carbonate in controlling serum phosphate?
In an asthma emergency, what are the advantages and disadvantages of a nebuliser compared with filling up a spacer with multiple Ventolin squirts?
In cases of dry age-related macular degeneration, does UV protection make a difference to macula pigment readings?
In cases of metastatic squamous cell carcinoma (SCC) in cervical lymph nodes with occult primary, in which circumstances is prophylactic wide field radiotherapy to potential primary sites beneficial in terms of loco-regional control and overall survival.
In cases of metastatic squamous cell carcinoma (SCC) in cervical lymph nodes with occult primary, is there any benefit in carrying out a PET/CT scan to locate the primary tumour?
In diabetic patients with retinopathy why does the retinopathy progress after cataract surgery?
In female patients complaining of loss of libido is there any evidence that hormone therapy (oestrogen or progestogen or androgen) is beneficial?
In individuals with cleft lip/palate what is the most effective speech therapy to eliminate cleft type speech characteristics?
In individuals with cleft lip/palate when is the most effective age to begin speech therapy?
In patients identified on primary examination as exhibiting possible COAG, OHT or glaucoma suspect status, what is the comparative effectiveness of diagnosis by different healthcare professions?
In patients who have pressure ulcers, would a supporting frame be a more effective means of relieving pressure than an air bed?
In patients with asthma on inhaled steroids are symptoms better controlled or side effects improved when taking steroid using a Metered Dose Inhaler (MDI) and spacer or breath activated device?
In patients with asthma on oral steroids, which drugs/intervention are needed/effective in preventing or treating hypertension?
In patients with asthma on oral steroids, which drugs/intervention are needed/effective in preventing or treating loss of growth in children?
In patients with chronic, 'hard-to-heal', complex wounds treated by the MIST Therapy system compared with those treated by standard methods of wound care
In patients with Venous thromboembolism and active cancer who have had 6 months of anticoagulation treatment with low molecular weight heparin (LMWH), what is the clinical benefit (in terms of VTE recurrence rates, all-cause mortality and major bleeding) and cost effectiveness of continued anticoagulation treatment with LMWH versus a vitamin K antagonist (VKA)?
In people after stroke what is the clinical and cost effectiveness of intensive rehabilitation versus moderate rehabilitation?
In people aged under 40 years with hypertension, what are the appropriate thresholds for intervention?
In people aged under 40 years with hypertension, what is the most accuratemethod of assessing the lifetime risk of cardiovascular events and the impactof therapeutic intervention on this risk?
In people who have not undergone revascularisation after an MI, does clopidogrel and placebo have a better outcome than clopidogrel and aspirin?
In people with a common mental health disorder, what is the clinical utility of routine outcome measurement and is it cost effective compared with standard care?
In people with acute ST-segment elevation myocardial infarction (STEMI) who present more than 1 hour after the onset of symptoms, is a primary PCI-related delay of 120-180 minutes associated with outcomes similar to, better orworse than pre-hospital administered fibrinolysis?
In people with chronic schizophrenia who have to stop clozapine, what is the most appropriate choice of antipsychotic in terms of symptom control and quality of life?
In people with multiple sclerosis which analgesics are effective and safe for the treatment of pressure-ulcer related pain?
In people with neurogenic lower urinary tract dysfunction, which management strategies (including the use of prophylactic antibiotics and various invasive and non-invasive techniques to aid bladder drainage) reduce the risk of symptomatic urinary tract infections?
In people with osteoarthritis what are their pre operative predictors of post operative success and risk factors of poor outcomes
In people with osteoarthritis, are there treatments that can modify joint structure?, resulting in delayed structural progression and improved outcomes?
In people with suspected anxiety disorders, what is the clinical utility of using the GAD-2 compared with routine case identification to accurately identify different anxiety disorders?
In people with thyroid eye disease, is there some way to filter the blood to remove whatever it is that prompts the immune system to think that the eye muscle cells are foreign?
In the patient with severe asthma which deteriorates in pregnancy what is the best way to manage and monitor the condition?
In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction
In which circumstances is post operative radiotherapy to lymph node areas beneficial for Head and Neck cancer in terms of improving local control and overall survival?
Incentive spirometry for preventing pulmonary complications after coronary artery bypass graft
Incentive spirometry for prevention of postoperative pulmonary complications in upper abdominal surgery
Incentive-based and non-incentive-based interventions for increasing blood donation
Incentives for attending new entrant screening for tuberculosis
Incentives for homeless people attending chest X-ray screening for tuberculosis
Incentives for increasing prenatal care use by women in order to improve maternal and neonatal outcomes
Incentives for lay health workers to improve recruitment, retention in service and performance
Incentives for preventing smoking in children and adolescents
Increased consumption of fruit and vegetables for the primary prevention of cardiovascular diseases
Increased sunscreen use to reduce incidences of skin cancer
Indacaterol, a once-daily beta2-agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease
Individual and group based parenting programmes for improving psychosocial outcomes for teenage parents and their children
Individual Cognitive Behavioural Therapy for children with depression
Individual interventions by breast cancer nurses' and the effact on quality of life outcomes for women with breast cancer
Individual versus group Cognitive Behavoural Therapy for children and young people with social anxiety disorder
Individual-, family-, and school-level interventions for preventing multiple risk behaviours in individuals aged 8 to 25 years
Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy with or without adjuvant chemotherapy for locally advanced nasopharyngeal carcinoma
Induction of labour for improving birth outcomes for women at or beyond term
Induction of labour for suspected fetal macrosomia
Indwelling bladder catheterisation as part of intraoperative and postoperative care for caesarean section
Indwelling bladder catheterization as part of postoperative care for caesarean section
Infant pacifiers for reduction in risk of sudden infant death syndrome
Infant position in neonates receiving mechanical ventilation
Infection control strategies for preventing the transmission of meticillin-resistant Staphylococcus aureus (MRSA) in nursing homes for older people
Inferior turbinate surgery for nasal obstruction in allergic rhinitis after failed medical treatment
Infliximab for induction of remission of ulcerative colitis
Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions
Influenza vaccination in children being treated with chemotherapy for cancer
Influenza vaccines for preventing acute otitis media in infants and children
Influenza vaccines in immunosuppressed adults with cancer
Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting
Information and communication technology based prompting for treatment compliance for people with serious mental illness
Information and communication technology in patient education and support for people with schizophrenia
Information and communication technology-based cognitive remediation for supporting treatment compliance for people with serious mental illness
Information giving to improve outcomes for Crohn's disease
Information interventions for orienting patients and their carers to cancer care facilities
Information provision for people with multiple sclerosis
Information provision for stroke patients and their caregivers
Information provision to prevent skin cancer
Information technology and electronic devices for people with autism spectrum conditions to improve social skills and other outcomes
Informative value of clinical research on multislice computed tomography in the diagnosis of coronary artery disease
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm
Infraorbital nerve block for postoperative pain following cleft lip repair in children
Infrared laser treatment for acne
Inhalation versus intravenous technique for rapid emergence from anaesthesia in patients undergoing brain tumour surgery
Inhaled analgesia for pain management in labour
Inhaled antibiotics for long-term therapy in cystic fibrosis
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis
Inhaled anticholinergics and short-acting beta2-agonists versus short-acting beta2-agonists alone for children with acute asthma in hospital
Inhaled beta2-agonist and anticholinergic agents for emergency management of asthma in adults
Inhaled beta2-agonists for asthma in mechanically ventilated patients
Inhaled bronchodilators for acute chest syndrome in people with sickle cell disease
Inhaled corticosteroid prophylaxis for exercise induced bronchoconstriction
Inhaled corticosteroids for cystic fibrosis
Inhaled corticosteroids for stable chronic obstructive pulmonary disease
Inhaled corticosteroids for subacute and chronic cough in adults, reduction in cough severity, complications of cough, inflammation and adverse effects
Inhaled corticosteroids for subacute cough in children
Inhaled corticosteroids in children with persistent asthma: dose-response effects on growth
Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth
Inhaled corticosteroids in children with persistent asthma: effects on growth
Inhaled corticosteroids versus long-acting beta2-agonists for chronic obstructive pulmonary disease
Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma
Inhaled hyperosmolar agents for bronchiectasis
Inhaled magnesium sulfate in the treatment of acute asthma
Inhaled nitric oxide for respiratory failure in preterm infants
Inhaled nitric oxide for the postoperative management of pulmonary hypertension in infants and children with congenital heart disease
Inhaled or nebulised corticosteroids for hospitalised children with acute asthma
Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease
Inhaled steroids for acute asthma following emergency department discharge
Inhaled versus systemic corticosteroids for preventing chronic lung disease in ventilated very low birth weight preterm neonates
Inhaled versus systemic corticosteroids for the treatment of chronic lung disease in ventilated very low birth weight preterm infants
Initial antithyroid drugs followed by thyroxine or no treatment for primary hyperthyroidism
Initial arch wires for tooth alignment during orthodontic treatment with fixed appliances
Injectable vaccines for preventing pneumococcal infection in patients with chronic obstructive pulmonary disease
Injection of allergen-antibody complexes of house dust mites for atopic eczema
Injection therapies for Achilles tendinopathy
Injection therapy for subacute and acute low back pain
Innovative technologies for the management of severe acute respiratory failure
Inositol for respiratory distress syndrome in preterm infants
Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome
Inpatient admission versus day hospital for schizophrenia
Inpatient versus outpatient care, partial hospitalisation and wait-list for people with eating disorders
Insoles for low back pain
Inspiratory muscle stength training vs endurance training in patients with COPD to improve maximal inspiratory pressure and functional exercise capacity
Inspiratory muscle training and physical training for reducing neuromuscular dysfunction in critically ill adults in intensive care units
Inspiratory muscle training for asthma
Inspiratory muscle training for cystic fibrosis
Inspiratory muscle training for the recovery of function after stroke
Instruments for assessing readiness to commence suck feeds in preterm infants: effects on time to establish full oral feeding and duration of hospitalisation
Instruments for chorionic villus sampling for prenatal diagnosis
Insulin and oral agents for managing cystic fibrosis-related diabetes
Insulin delivery methods, other than injection.
Insulin detemir versus insulin glargine for type 2 diabetes mellitus
Insulin for glycaemic control in acute ischaemic stroke
Insulin therapy for glycaemic control in critically ill children
Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility
Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome
Integrated and non-integrated orbital implants for treating anophthalmic sockets
Integrated disease management interventions for patients with chronic obstructive pulmonary disease
Integrated Management of Childhood Illness (IMCI) Strategy for children under five: effects on death, service utilisation and illness
Integration of HIV/AIDS services with maternal, neonatal and child health, nutrition, and family planning services
Intense pulsed light therapy for acne
Intensity of continuous renal replacement therapy for acute kidney injury
Intensity-modulated versus conventional radiotherapy for breast cancer
Intensive Case Management for severe mental illness
Intensive glucose control versus conventional glucose control for type 1 diabetes mellitus
Intensive stop smoking interventions for people using mental health services
Intensive versus conventional glycaemic control for treating diabetic foot ulcers
Interactive computer-based interventions for sexual health promotion
Interactive computer-based interventions for weight loss or weight maintenance in overweight or obese people
Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes
Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes
Interdental brushing for the management of periodontal diseases and dental caries in adults
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults
Interentions to develop the emotional and social skills of vulnerable, preschool children
Interferon after surgery for women with advanced (Stage II-IV) epithelial ovarian cancer
Interferon Alpha Adjuvant Therapy in Patients with High-Risk Melanoma
Interferon alpha for chronic hepatitis D
Interferon alpha for the adjuvant treatment of cutaneous melanoma
Interferon alpha-2b and ribavirin maintenance therapy for halting hepatitis C disease progression in liver-transplanted patients
Interferon beta for primary progressive multiple sclerosis
Interferon for interferon nonresponding and relapsing patients with chronic hepatitis C
Interferon-gamma tests vs tuberculin skin tests for predicting subsequent development of active e tuberculosis (TB), or diagnosing or ruling out current active TB when undertaking TB screening
Interferons-beta versus glatiramer acetate for relapsing-remitting multiple sclerosis
Interleukin-1 inhibitors for chronic gout
Interleukin-2 as maintenance therapy for children and adults with acute myeloid leukaemia in first complete remission
Intermittent catheterisation and indwelling catheters as first choice treatment for urinary incontinence
Intermittent drug techniques for schizophrenia
Intermittent inhaled corticosteroid therapy versus placebo for persistent asthma in children and adults
Intermittent iron supplementation for improving nutrition and development in children under 12 years of age
Intermittent iron supplementation for reducing anaemia and its associated impairments in menstruating women
Intermittent oral iron supplementation during pregnancy
Intermittent pneumatic compression for treating venous leg ulcers
Intermittent preventive antimalarial treatment for children with anaemia
Intermittent self-dilatation for urethral stricture disease in men
Intermittent versus continuous androgen suppression for prostatic cancer
Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
Intermittent versus daily therapy for treating tuberculosis in children
Internal dressings for healing perianal abscess cavities
Internal fixation for treating distal radius fractures in adults
Internal fixation implants for intracapsular hip fractures in adults
Internal fixation versus arthroplasty for intracapsular proximal femoral fractures in adults
Internal fixation versus other surgical methods for treating distal radius fractures in adults
Internal radiation therapy (SIRT) for on-resectable colorectal metastases in the liver
Internal versus external tocodynamometry during induced or augmented labour
Internet interventions for treatment of alcohol-related problems
Internet-based interventions for smoking cessation
Interobserver variation in the delineation of target volumes using positron emission tomography for non-small cell lung cancer patients with atelectasis
Interpersonal, cognitive analytic and other integrative therapies versus treatment as usual for depression
Interposition vein cuff for infragenicular prosthetic bypass graft
Interprofessional education: effects on professional practice and healthcare outcomes (update)
Interval debulking surgery for advanced epithelial ovarian cancer
Intervention for developmental apraxia of speech
Intervention for prostate cancer prevention approaches
Interventionist versus expectant care for severe pre-eclampsia between 24 and 34 weeks' gestation
Interventions (other than pharmacological, psychosocial or psychological) for treating antenatal depression
Interventions at caesarean section for reducing the risk of aspiration pneumonitis
Interventions based on the Theory of Mind cognitive model for autism spectrum disorder (ASD)
Interventions before pregnancy to improve pregnancy outcomes for women with epilepsy and their offspring
Interventions designed to prevent healthcare bed-related injuries in patients
Interventions for actinic keratoses
Interventions for acute auricular haematoma
Interventions for acute internal hordeolum
Interventions for age-related visual problems in patients with stroke
Interventions for anal canal intraepithelial neoplasia
Interventions for apathy after traumatic brain injury
Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment
Interventions for atrophic rhinitis
Interventions for auditory processing disorder
Interventions for both male and female sexual dysfunction in chronic kidney disease
Interventions for bronchiectasis: an overview of Cochrane systematic reviews
Interventions for cachexia-anorexia syndrome in people with lung cancer
Interventions for caregivers for the recognition of disease-related complications in children with sickle cell disease
Interventions for children exposed to trauma other than maltreatment
Interventions for chronic blepharitis
Interventions for chronic idiopathic urticaria excluding antihistamines
Interventions for chronic kidney disease-associated restless legs syndrome
Interventions for chronic non-hypovolaemic hypotonic hyponatraemia
Interventions for clinical and subclinical hypothyroidism pre-pregnancy and during pregnancy
Interventions for congenital ichthyosis
Interventions for congenital talipes equinovarus (clubfoot)
Interventions for congenital talipes equinovarus (clubfoot)
Interventions for cough in cancer
Interventions for covert bacteriuria in children
Interventions for cutaneous Bowen's disease
Interventions for cutaneous sarcoidosis
Interventions for disorders of eye movement in patients with stroke
Interventions for dissociated vertical deviation
Interventions for drooling in children with cerebral palsy
Interventions for drug-using offenders with co-occurring mental illness
Interventions for dysphagia and nutritional support in acute and subacute stroke
Interventions for ear discharge associated with grommets (ventilation tubes)
Interventions for emergency contraception
Interventions for enhancing adherence to treatment in adults with bronchiectasis
Interventions for erosive lichen planus affecting mucosal sites
Interventions for erythrodermic psoriasis
Interventions for erythropoietin-resistant anaemia in dialysis patients
Interventions for established stretch marks
Interventions for facial palsy associated with Lyme disease
Interventions for failure of the initial course of antibiotics for Lyme disease
Interventions for fatigue and weight loss in adults with advanced progressive illness
Interventions for fatigue in Parkinson's disease
Interventions for female drug-using offenders
Interventions for female pattern hair loss
Interventions for fetal immobilisation during fetal surgery and invasive procedures
Interventions for generalised anxiety disorder in older people with cognitive decline
Interventions for guttate psoriasis
Interventions for helping people adhere to compression treatments for venous leg ulceration
Interventions for helping people recognise early signs of recurrence in depression
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version
Interventions for hidradenitis suppurativa
Interventions for hirsutism excluding laser and photoepilation therapy
Interventions for HIV-associated nephropathy
Interventions for hyperthyroidism pre-pregnancy and during pregnancy
Interventions for iatrogenic inferior alveolar and lingual nerve injury
Interventions for impetigo
Interventions for implementation of thromboprophylaxis in hospitalized medical and surgical patients at risk for venous thromboembolism
Interventions for improving adherence to ocular hypotensive therapy
Interventions for improving asthma care in ethnic minorities
Interventions for improving community ambulation in individuals with stroke
Interventions for improving coverage of child immunization in low- and middle-income countries
Interventions for improving medication adherence in patients with idiopathic Parkinson's disease
Interventions for improving medication reconciliation across transitions of care
Interventions for improving mobility after hip fracture surgery in adults
Interventions for improving modifiable risk factor control in the secondary prevention of stroke
Interventions for improving outcomes for pregnant women who have experienced genital cutting
Interventions for improving outcomes in patients with multimorbidity in primary care and community settings
Interventions for improving palliative care for older people living in nursing care homes
Interventions for improving patients' trust in doctors and groups of doctors
Interventions for improving reproductive outcomes in women with recurrent implantation failure undergoing assisted reproductive techniques
Interventions for improving sit-to-stand ability following stroke
Interventions for improving upper limb function after stroke
Interventions for increasing acceptance of local anaesthetic in children having dental treatment
Interventions for increasing fruit and vegetable consumption in children aged 5 years and under
Interventions for increasing health promotion practices in dental healthcare settings
Interventions for increasing solid organ donor registration
Interventions for induction and maintenance of mucosal healing in Crohn's disease
Interventions for induction of mucosal healing in ulcerative colitis
Interventions for infantile esotropia
Interventions for infantile haemangiomas (strawberry birthmarks) of the skin
Interventions for infected cysts in people with autosomal dominant polycystic kidney disease
Interventions for ingrowing toenails
Interventions for insomnia in conjunction with antipsychotic drug use
Interventions for intermittent exotropia
Interventions for intertriginous or flexural psoriasis
Interventions for involutional lower lid entropion
Interventions for late trabeculectomy bleb leak
Interventions for leg cramps in pregnancy
Interventions for maintenance of mucosal healing in ulcerative colitis
Interventions for managing asthma in pregnancy
Interventions for managing relapse of the lower front teeth after orthodontic treatment
Interventions for melanoma in situ, including lentigo maligna
Interventions for men and women with their first episode of genital herpes
Interventions for Mooren's ulcer
Interventions for mycosis fungoides
Interventions for nail psoriasis
Interventions for nausea and vomiting in early pregnancy
Interventions for neovascular age-related macular degeneration
Interventions for neuropathic pain in Lyme disease
Interventions for non-oliguric hyperkalaemia in preterm neonates
Interventions for non-tubal ectopic pregnancy
Interventions for normal tension glaucoma
Interventions for obsessive compulsive symptoms in people with schizophrenia
Interventions for oropharyngeal dysphagia in children with neurological impairment
Interventions for Paget’s disease of the vulva
Interventions for patients and caregivers to improve knowledge of sickle cell disease and recognition of its related complications
Interventions for periodontal disease in people with rheumatoid arthritis
Interventions for post-transplant anaemia in kidney transplant recipients
Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteria
Interventions for preoperative smoking cessation
Interventions for preventing abuse in the elderly
Interventions for preventing and reducing the use of physical restraints in long-term geriatric care
Interventions for preventing and treating hyperthyroidism in pregnancy
Interventions for preventing and treating pelvic and back pain in pregnancy
Interventions for preventing and treating squamous cell carcinoma of the conjunctiva in HIV-infected individuals
Interventions for preventing blood loss during the treatment of cervical intraepithelial neoplasia
Interventions for preventing critical illness polyneuropathy and critical illness myopathy
Interventions for preventing delirium in hospitalised patients
Interventions for preventing delirium in older people in institutional long-term care
Interventions for preventing excessive weight gain during pregnancy
Interventions for preventing falls in older people in care facilities and hospitals
Interventions for preventing falls in older people living in the community
Interventions for preventing falls in people after stroke
Interventions for preventing infection in nephrotic syndrome
Interventions for preventing intensive care unit delirium
Interventions for preventing mastitis after childbirth
Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section
Interventions for preventing neuropathy caused by cisplatin and related compounds
Interventions for preventing non-melanoma skin cancers in high risks groups?
Interventions for preventing or reducing domestic violence against pregnant women
Interventions for preventing oral mucositis for patients with cancer receiving treatment
Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery
Interventions for preventing recurrent urinary tract infection during pregnancy
Interventions for preventing relapse and recurrence after the first episode of a depressive disorder in young people
Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents
Interventions for preventing silent cerebral infarcts in people with sickle cell disease
Interventions for preventing the progression of autosomal dominant polycystic kidney disease
Interventions for preventing the spread of infestation in close contacts of people with scabies
Interventions for preventing weight gain after smoking cessation
Interventions for prevention and treatment of vulvovaginal candidiasis in women with HIV infection
Interventions for prevention of giant retinal tear in the fellow eye
Interventions for prevention of herpes simplex labialis (cold sores on the lips)
Interventions for primary (intrinsic) tracheomalacia in children
Interventions for primary prevention of occupational asthma
Interventions for promoting habitual exercise in people living with and beyond cancer
Interventions for promoting participation in shared decision-making for children with cancer
Interventions for promoting physical activity in people with cystic fibrosis
Interventions for protecting renal function in the perioperative period
Interventions for providers to promote a patient-centred approach in clinical consultations
Interventions for psoriasis in children
Interventions for psoriasis in obese people
Interventions for psoriasis in people with hepatitis C
Interventions for psoriasis in people with HIV infection
Interventions for psychiatric symptoms associated with Lyme disease
Interventions for psychosis in adolescents
Interventions for psychotic symptoms concomitant with epilepsy
Interventions for recruiting smokers into cessation programmes
Interventions for recurrent corneal erosions
Interventions for recurrent idiopathic epistaxis (nosebleeds) in children
Interventions for reducing adverse health effects of high temperature and heatwaves
Interventions for reducing anxiety in women undergoing colposcopy
Interventions for reducing inflammation in familial Mediterranean fever
Interventions for reducing itch in atopic eczema
Interventions for reducing medication errors in hospitalised adults
Interventions for reducing wrong-site surgery and invasive procedures
Interventions for relapse in Lyme disease following completion of treatment regimen
Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus
Interventions for replacing missing teeth: different types of dental implants
Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants
Interventions for replacing missing teeth: partially absent dentition
Interventions for replacing missing teeth: treatment of peri-implantitis
Interventions for restoring patency of occluded central venous catheter lumens
Interventions for rosacea
Interventions for segmental vitiligo
Interventions for severe scalp psoriasis
Interventions for sexual dysfunction following stroke
Interventions for sexual dysfunction following treatments for cancer – excluding PDE5 inhibitors
Interventions for smokeless tobacco use cessation
Interventions for smoking cessation and reduction in individuals with schizophrenia
Interventions for smoking cessation in hospitalised patients
Interventions for smoking cessation in Indigenous populations
Interventions for squamous cell carcinoma of the conjunctiva in HIV-infected individuals
Interventions for stimulus deprivation amblyopia
Interventions for strabismic amblyopia
Interventions for strabismic amblyopia
Interventions for supporting parents' decisions about autopsy after stillbirth
Interventions for supporting pregnant women's decision-making about mode of birth after a caesarean
Interventions for supporting women with decisions about mode of birth in a pregnancy after caesarean birth
Interventions for the eradication of methicillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis
Interventions for the management of dry mouth: non-pharmacological interventions
Interventions for the management of dry mouth: topical therapies
Interventions for the management of malignant pleural effusions
Interventions for the management of mandibular fractures
Interventions for the management of oral submucous fibrosis
Interventions for the management of oral ulcers in Behcet's disease
Interventions for the management of taste disturbances
Interventions for the management of temporomandibular joint osteoarthritis
Interventions for the prevention of mycobacterium avium complex in adults and children with HIV
Interventions for the prevention of postoperative atrial fibrillation in adult patients undergoing noncardiac thoracic surgery
Interventions for the prevention of postoperative ear discharge after insertion of ventilation tubes (grommets) in children
Interventions for the reduction of prescribed opioid use in chronic non-cancer pain
Interventions for the reduction of prescribed opioid use in chronic non-cancer pain
Interventions for the reduction of shoulder pain following gynaecological laparoscopic procedures
Interventions for the restorative care of amelogenesis imperfecta in children and adolescents
Interventions for the symptoms and signs resulting from jellyfish stings
Interventions for the symptoms and signs resulting from jellyfish stings
Interventions for the treatment of borderline ovarian tumours
Interventions for the treatment of Frey's syndrome
Interventions for the treatment of keratocystic odontogenic tumours (KCOT, odontogenic keratocysts (OKC))
Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment
Interventions for the treatment of oral and oropharyngeal cancers: targeted therapy and immunotherapy
Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy
Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy
Interventions for the treatment of Paget's disease of the vulva
Interventions for the treatment of pityriasis versicolor
Interventions for the treatment of twin-twin transfusion syndrome
Interventions for tobacco cessation in the dental setting
Interventions for tobacco use cessation in people in treatment for or recovery from substance abuse
Interventions for tobacco use cessation in people living with HIV and AIDS
Interventions for tobacco use prevention in Indigenous youth
Interventions for tophi in gout
Interventions for treating acute bleeding episodes in people with acquired hemophilia
Interventions for treating acute elbow dislocations in adults
Interventions for treating AIDS-associated Hodgkin acute lymphoma in treatment-naive adults
Interventions for treating ankle fractures in children
Interventions for treating anxiety after stroke
Interventions for treating cholestasis in pregnancy
Interventions for treating chronic ankle instability
Interventions for treating femoral shaft fractures in children and adolescents
Interventions for treating fingertip entrapment injuries in children
Interventions for treating fractures of the distal femur in adults
Interventions for treating gas gangrene
Interventions for treating genital Chlamydia trachomatis infection in pregnancy
Interventions for treating hyperemesis gravidarum
Interventions for treating inadvertent postoperative hypothermia
Interventions for treating injuries of the medial ligaments of the knee
Interventions for treating intrahepatic cholestasis in people with sickle cell disease
Interventions for treating isolated diaphyseal fractures of the ulna in adults
Interventions for treating leg ulcers in people with sickle cell disease
Interventions for treating oral candidiasis for patients with cancer receiving treatment
Interventions for treating oral leukoplakia
Interventions for treating oral mucositis for patients with cancer receiving treatment
Interventions for treating osteoarthritis of the big toe joint
Interventions for treating overweight or obesity in adults: an overview of systematic reviews
Interventions for treating pain and disability in adults with complex regional pain syndrome
Interventions for treating peripartum cardiomyopathy to improve outcomes for women and babies
Interventions for treating persistent and intractable hiccups in adults
Interventions for treating phosphorus burns
Interventions for treating phosphorus burns
Interventions for treating placental abruption
Interventions for treating postpartum constipation
Interventions for treating proximal humeral fractures in adults
Interventions for treating sexual dysfunction in patients with chronic kidney disease
Interventions for treating simple bone cysts in the long bones of children
Interventions for treating slipped upper femoral epiphysis (SUFE)
Interventions for treating supracondylar fractures of the humerus in children
Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth
Interventions for treating ulnar collateral ligament injuries of the thumb
Interventions for treating urinary stones in children
Interventions for treatment of chronic hepatitis B in lamivudine-resistant patients
Interventions for undescended testes in children
Interventions for unilateral and bilateral refractive amblyopia
Interventions for unilateral refractive amblyopia
Interventions for vaginismus
Interventions for visual field defects in patients with stroke
Interventions for vitiligo in children
Interventions for women in subsequent pregnancies following obstetric anal sphincter injury for improving health
Interventions in diverse health care settings for practitioners working with people who are experiencing domestic violence and abuse
Interventions in the workplace to support breastfeeding for women in employment
Interventions other than anticoagulants and systemic antibiotics for prevention of central venous catheter-related infections in children with cancer
Interventions to aid staying at or returning to work during or following Lyme disease
Interventions to build resilience in children of problem drinkers
Interventions to correct chronic metabolic acidosis in patients with chronic kidney disease
Interventions to encourage uptake of cancer screening for people with severe mental illness
Interventions to enhance adherence to dietary advice for preventing and managing chronic diseases in adults
Interventions to enhance return-to-work for cancer patients
Interventions to facilitate return to work in adults with adjustment disorders
Interventions to improve adherence to antiretroviral therapy in children with HIV infection
Interventions to improve adherence to guidelines on 'Standard Precautions' for the control of healthcare-associated infections
Interventions to improve antibiotic prescribing practices for hospital inpatients
interventions to improve antibiotic prescribing practices for hospital inpatients (updated protocol)
Interventions to improve attitudes towards treatment and treatment compliance among adolescents with attention deficit-hyperactivity disorder (ADHD)
Interventions to improve compliance with treatment in schizophrenia
Interventions to improve continuity of care in the follow-up of patients with cancer
Interventions to improve disposal of child faeces for preventing diarrhoea and soil-transmitted helminth infection
Interventions to improve evidence-based prescribing in heart failure
Interventions to improve hearing aid use in adult auditory rehabilitation
Interventions to improve occupational health in depressed people
Interventions to improve professional adherence to guidelines for prevention of device-related infections
Interventions to improve safe and effective medicines use by consumers: an overview of systematic reviews
Interventions to improve the appropriate use of polypharmacy for older people
Interventions to improve the use of systematic reviews in decision-making by health system managers, policy makers and clinicians
Interventions to improve vaginal health for reducing the risk of HIV acquisition
Interventions to improve water quality and supply, sanitation and hygiene practices, and their effects on the nutritional status of children
Interventions to increase clinical incident reporting in health care
Interventions to increase influenza vaccination rates of those 60 years and older in the community
Interventions to increase physical activity for people with congenital heart disease
Interventions to increase the reporting of occupational diseases by physicians
Interventions to manage dual practice among health workers
Interventions to optimise prescribing for older people in care homes
Interventions to prevent injuries in construction workers
Interventions to prevent occupational noise-induced hearing loss
Interventions to prevent or manage obesity in children and adults in the UK
Interventions to prevent or manage obesity in different population groups
Interventions to prevent sleep disruption in infants with atopic eczema
Interventions to prevent steroid-induced osteoporosis and osteoporotic fractures in Duchenne muscular dystrophy
Interventions to promote informed consent for patients undergoing surgical and other invasive healthcare procedures
Interventions to promote the use of seat belts
Interventions to promote the wearing of hearing protection
Interventions to reduce ambient particulate matter air pollution and their effect on health
Interventions to reduce experiences of stigma and discrimination of people with mental illness and their caregivers
Interventions to reduce haemorrhage during myomectomy for fibroids
Interventions to reduce or relieve the pain and discomfort of screening mammography
Interventions to reduce risky sexual behaviour for preventing HIV infection in workers in occupational settings
Interventions to reduce Staphylococcus aureus in the management of atopic eczema
Interventions to reduce unintended conception and abortion rates among young people aged under 25 years on subgroups of socially disadvantaged young people
Interventions to reduce weight gain in schizophrenia
Interventions to slow progression of myopia in children
Interventions to support return-to-work for patients with coronary heart disease
Interventions when Lyme disease symptoms are failing to respond during treatment
Interventions with families of alcohol misusers
Intestinal dysfunction and QOL in patients with or without radiotherapy after rectal cancer resection
Inteventions to achieve continuity of care for prisoners who are diagnosed with chronic hepatitis B or C in prison?
Intra-aortic balloon pump counterpulsation (IABP) for myocardial infarction complicated by cardiogenic shock
Intra-arterial chemotherapy for high-grade gliomas
Intra-articular analgesia for anterior cruciate ligament reconstruction
Intra-articular glucocorticoids for acute gout
Intra-articular hyaluronate for rheumatoid arthritis
Intra-articular lignocaine versus intravenous analgesia with or without sedation for manual reduction of acute anterior shoulder dislocation in adults
Intracutaneous or subcutaneous sterile water injection compared with blinded controls for pain management in labour
Intracystic bleomycin for cystic craniopharyngiomas in children
Intralesional treatment versus wide resection for central chondrosarcoma grade I in the long bones
Intramedullary nailing for femoral shaft fractures in adults
Intramedullary nailing for tibial shaft fractures in adults
Intramedullary nails for extracapsular hip fractures in adults
Intramural urethral bulking procedures for stress urinary incontinence in women
Intramuscular versus intravenous anti-D for preventing Rhesus alloimmunization during pregnancy
Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour
Intranasal corticosteroids for non-allergic rhinitis
Intranasal fentanyl for the management of acute pain in children
Intranasal ipratropium bromide for the common cold
Intranasal ipratropium bromide with placebo for seasonal allergic rhinitis
Intranasal or transdermal nicotine for the treatment of postoperative pain
Intranasal oxytocin for autism spectrum disorders (ASD)
Intranasal steroids for acute sinusitis
Intraoperative 5-Fluorouracil for glaucoma surgery
Intra-operative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses
Intra-operative imaging for neuro-oncology
Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents
Intraoperative mild hypothermia for postoperative neurological deficits in intracranial aneurysm patients
Intra-operative Mitomycin C for glaucoma surgery
Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of stay and lung injury in patients without acute lung injury
Intraopetarive Radiotherapy for Solid Tumours
Intrapartum antibiotics for known maternal Group B streptococcal colonization
Intraperitoneal carboplatin versus cisplatin for primary epithelial ovarian cancer
Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy
Intrastromal corneal ring segments for treating keratoconus
Intratracheal Clara cell secretory protein (CCSP) administration in preterm infants with or at risk of respiratory distress syndrome
Intratympanic gentamicin for Meniere's disease or syndrome
Intratympanic gentamicin in Ménière's disease
Intratympanic steroids for Ménière's disease and sudden sensorineural hearing loss
Intratympanic steroids for Ménière's disease or syndrome
Intra-uterine insemination for unexplained subfertility
Intrauterine insemination versus fallopian tube sperm perfusion for non-tubal infertility
Intravascular brachytherapy for peripheral vascular disease
Intra-vascular spread of Prostate Cancer by retorgrade saline 'transfusion' through the cut surface of the prostate during transurethral resection of the prostate (TURP)
Intravenous adrenaline in patients with cardiac arrest out of hospital
Intravenous antibiotic therapy vs oral antibiotic therapy within the first 24 hours of treatment in patients with neutropenic sepsis who are having treatment with intravenous antibiotics
Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis
Intravenous beta2-agonists versus intravenous aminophylline for acute asthma
Intravenous cetraxone for late Lyme disease
Intravenous fluids for reducing the duration of labour in low risk nulliparous women
Intra-venous fluids for the prevention of severe ovarian hyperstimulation syndrome
Intravenous hyoscine-N-butyl bromide for aiding colonoscopy
Intravenous immunoglobulin as a corticosteroid sparing agent for chronic asthma
Intravenous immunoglobulin as adjuvant therapy for Wegener's granulomatosis
Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy
Intravenous immunoglobulin for Guillain-Barr? syndrome
Intravenous immunoglobulin for myasthenia gravis
Intravenous immunoglobulin for preventing infection in preterm and/or low birth weight infants
Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock
Intravenous immunoglobulin for treating sepsis, severe sepsis and septic shock
Intravenous immunoglobulin to prevent relapses during pregnancy and postpartum in multiple sclerosis
Intravenous inotropic drugs in acute heart failure
Intravenous lidocaine for the treatment of background or procedural burn pain
Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department
Intravenous magnesium sulfate for treating children with acute asthma in the emergency department
Intravenous magnesium sulphate for acute severe asthma
Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit
Intravenous naftidrofuryl for critical limb ischaemia
Intravenous nitrates or intravenous furosemide for acute heart failure
Intravenous polyclonal human immunoglobins for relapse-remitting multiple sclerosis
Intravenous secretin for autism spectrum disorders (ASD)
Intravenous valproate for status epilepticus
Intravenous versus inhalation anaesthesia for one-lung ventilation
Intravenous versus inhalation anaesthesia for patients undergoing on-pump or off-pump coronary artery bypass grafting
Intravenous versus inhalational anaesthesia for paediatric outpatient surgery
Intravenous versus oral antibiotic treatment for Lyme disease
Intraventricular antibiotics for bacterial meningitis in neonates
Intravesical Bacillus Calmette-Guerin versus epirubicin for Ta and T1 bladder cancer
Intravesical gemcitabine for non-muscle invasive bladder cancer
Intravitreal bevacizumab (Avastin) vs. ranibizumab (Lucentis) for the treatment of age-related macular degeneration
Intravitreal corticosteroids to improve visual acuity in branch retinal vein occlusion
Intravitreal corticosteroids to improve visual acuity in central retinal vein occlusion
Intravitreal injection of Triamcinolone for diabetic retinopathy
Intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors for diabetic retinopathy
Intravitreal low molecular weight heparin and 5-Fluorouracil for the prevention of proliferative vitreoretinopathy following retinal reattachment surgery
Intravitreal steroids versus observation for macular edema secondary to central retinal vein occlusion
Invasive urodynamic studies for the management of LUTS in men with voiding dysfunction
In-vitro screening to test whether ataluren (PTC124) can correct functional consequences of premature termination mutations of the Flavin containing monooxygenase 3 (FMO3) gene?
In-work tax credits for families and their impact on health status in adults
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders
Iodine solution for the prevention of chemotherapy-induced oral mucositis
Iodine-131-meta-iodobenzylguanidine therapy for patients with high-risk neuroblastoma
Iodised salt for preventing iodine deficiency disorders
Ionisers for chronic asthma
IQCODE for the diagnosis of Alzheimer's disease dementia and other dementias within a community setting
IQCODE for the diagnosis of Alzheimer's disease dementia and other dementias within a general practice (primary care) setting
IQCODE for the diagnosis of Alzheimer's disease dementia and other dementias within a secondary care setting
Iridectomy or iridotomy for preventing angle-closure glaucoma
Iron chelators for acute stroke
Iron for restless legs syndrome
Iron therapy for improving psychomotor development and cognitive function in children under the age of three with iron deficiency anaemia
Iron therapy in anaemic adults without chronic kidney disease
Irrigants for non-surgical root canal treatment in mature permanent teeth
Is training for carers and 'be-frienders' useful at promoting/supporting cognitive or occupational therapy activities for someone following a stroke?
Is 6 months of trastuzumab treatment sufficient when compared with 12 months?
Is a bath or shower more effective in improving healing and decrease infections for patients with dystrophic epidermolysis bullosa?
Is a change from dry age-related macular degeneration to wet age-related macular degeneration inevitable?
Is a closed loop system effective?
Is a combination of LH-RH analogue and oestrogen a valid treatment for advanced prostate cancer?
Is a combination of neuro-linguistic programming (NLP) and hypnosis an effective tinnitus management strategy?
Is a Digital Rectal Examination safe if performed shortly after biopsy for prostate cancer?
Is a genetic (molecular) diagnosis possible for all inherited retinal diseases?
Is a pancreas transplant effective?
Is a small dose of stimulant medication helpful in children with Autistic Spectrum Disorder (ASD) and learning disability to reduce hyperactive behaviours?
Is a 'young stroke environment' better than a geriatric/ stroke rehabilitation environment at improving recovery of young people after stroke?
Is acupuncture an effective tinnitus management strategy?
Is acupuncture effective for peripheral joint osteoarthritis?
Is adjuvant chemotherapy effective in patients with aggressive prostate cancer?
Is age-related macular degeneration affected by simvastatin (trade name Zocor)?
Is age-related macular degeneration worsened by reading (in a good light)?
Is amitriptyline a clinically and cost effective prophylactic treatment for recurrent migraine?
Is an artificial pancreas for type 1 diabetes (closed loop system) effective?
Is an individualised treatment approach that addresses the different components of the condition more effective than standard (audiological) care?
Is antidepressant medication safe for the foetus and mother if taken during pregnancy?
Is anti-reflux therapy an effective treatment for idiopathic pulmonary fibrosis?
Is any specific surgical intervention effective in Ménière's disease and what procedure is best?
Is anything known about why people with age-related macular degeneration suffer hallucinations?
Is ascorbic acid effective in managing anaemia in haemodialysis patients?
Is Atrovent for asthma less likely to cause giddiness, nausea, shaking, headache and palpitations than salbutamol or Ventolin?
Is betahistine an effective tinnitus treatment?
Is bibliotherapy effective for relieving psychotic symptoms?
Is bortezomib an effective therapy for Post Transplant Lymphoproliferative Disorders?
Is botox effective after stroke?
Is cannabis an effective treatment for multiple sclerosis?
Is carbogen gas effective in the treatment of sudden sensorineural hearing loss?
Is cataract surgery beneficial in cases where there is marked photosensitivity?
Is clozapine clinically and cost effective when compared with other pharmacological interventions for people with psychosis and coexisting substance misuse?
Is Clozapine particularly effective in reducing hostility, violence and reducing suicide rates in schizophrenia?
Is codeine an effective analgesic?
Is Cognitive Behaviour Therapy/psychological therapy, delivered by audiology professionals, effective for people with tinnitus?
Is Cognitive Behavioural Therapy equally effective for all psychiatric conditions?
Is Cognitive Behavioural Therapy equally useful in patients with and without active medication?
Is 'cold laser' treatment a possible treatment for drusen in dry age-related macular degeneration?
Is combining or alternating antipyretic therapy more beneficial than monotherapy for febrile children?
Is community-based stroke care clinically and cost-effective?
Is continuous medication beneficial for my asthma if I don't have symptoms?
Is conversation partner training useful in the management of aphasia after stroke?
Is corneal surgery a possible treatment for Stevens-Johnson Syndrome
Is corneal transplant a suitable treatment for people with corneal scarring?
Is counselling adequate for schizophrenia?
Is counselling better than anti-depressants for treating depression following stroke?
Is cycling an effective strategy for reducing hip dislocation in children and young people with cerebral palsy?
Is DAFNE an effective patient education system for people with diabetes?
Is daily use of a Becotide inhaler necessary for asthma in children?
Is debridement an effective treatment in ulcer healing?
Is depth of anaesthesia monitoring to prevent awareness effective and cost effective?
Is desmopressin effective in reducing nocturia and enuresis in elderly men?
Is desmopressin used for urinary incontinence safe and effective in patients over 60?
Is diet effective in slowing, stopping or reversing the accumulation of disability associated with multiple sclerosis?
Is dietary and lifestyle advice effective in the treatment of overactive bladder?
Is direct access audiology service beneficial for patients with tinnitus?
Is Disease Management more effective than good quality usual care for heart failure?
Is drug therapy effective to control drooling for children and young people with neurodisability?
Is drug therapy more effective than psychotherapy in treating emotional distress?
Is early intervention more effective in managing tinnitus distress?
Is early mobilisation (within 48 hours) beneficial after stroke?
Is early psychological support helpful after stroke?
Is early support discharge clinically and cost-effective for someone following a stroke?
Is early switching of opioid, on development of side effects, more effective at reducing central side effects than persisting with current opioid and dose reduction in patients starting strong opioids?
Is ECT advised to treat mood disorders in people with schizophrenia?
Is ECT more effective and/or safer for the foetus, in severe depressive states, during the perinatal period than antidepressant medication?
Is ECT over the long term effective in treating schizophrenia?
Is educational information, based on research, beneficial to people with tinnitus and their families?
Is examination or re-examination after a dose of antipyretic medication of benefit in differentiating children with serious illness from those with other conditions?
Is external beam radiotherapy effective for treating prostate cancer?
Is finasteride effective in reducing nocturia in benign prostatic hyperplasia?
Is fish oil effective at reducing nephrotoxicity in kidney transplant recipients?
Is functional electrical stimulation (FES) an effective rehabilitation aid for treating foot drop in people with multiple sclerosis?
Is group speech and language therapy better and does it cost less than individual speech and language therapy following stroke?
Is group therapy (led by a healthcare professional) an effective tinnitus management strategy? Here the comparisons might be with a patient-led support group or with one-to-one therapy.
Is group therapy a more effective tinnitus management strategy than one-to-one therapy?
Is growth hormone treatment effective for children with chronic kidney disease?
Is hair removal of benefit in Hidradenitis suppurativa?
Is hand and feet numbness associated with use of certain antiepileptic drugs?
Is Hidradenitis suppurativa an autoimmune disease?
Is homeopathic medication useful for asthma?
Is horse riding an effective therapy to improve functioning and promote wellbeing in children and young people with neurodisability?
Is hypnosis an effective tinnitus management strategy?
Is imiquimod useful to treat tumours in patients with dystrophic epidermolysis bullosa?
Is increased staffing and skill mix more effective in healing pressure ulcers than reliance on alternating air mattresses and other equipment for those at high risk?
Is information provision about swallowing problems adequate after stroke?
Is injected medication preferable to preventer inhalers for children with asthma?
Is insulin pump therapy effective? (immediate v deferred pump, and comparing outcomes with multiple injections)
Is intensive inpatient rehabilitation beneficial late (5-10 years) after stroke?
Is it better to inhale steroids for my asthma rather than take them as tablets?
Is it better to use dental implants or bridges in patients with dystrophic epidermolysis bullosa?
Is it helpful for patients with balance disorders to adopt a specific diet?
Is it helpful for patients with balance disorders to reduce/avoid salt intake?
Is it helpful in preventing the severity, frequency and progression of attacks of Ménière's disease to adopt a specific diet, or restrict salt, caffeine or fluid intake?
Is it known why in some cases patching is an effective treatment in strabismus, but other cases require surgery?
Is it known why some people develop thyroid eye disease following thyroid treatment, and others do not?
Is it necessary to take the preventive inhaler everyday?
Is it possible for sight loss in a person with vascular dementia to improve over time?
Is it possible for someone to self-detect thyroid eye disease before a medical diagnosis?
Is it possible to constantly and accurately monitor blood sugar levels, in people with type 1 diabetes, with a discrete device (microchip, implant for example) ?
Is it possible to detect corneal dystrophy early in children, to enable early treatment and potential halting of the disease progression?
Is it possible to diagnose branch retinal vein occlusion before it occurs, therefore preventing the consequences of the condition?
Is it possible to diagnose Stargardts' disease before vision is lost?
Is it possible to grow large numbers of healthy corneal endothelial cells from a small number of original cells from a patient and then transplant the new cells back into the patient to treat Fuch's corneal dystrophy?
Is it possible to identify strategies to reduce eye irritation produced by looking at TV or computer screens, for people with corneal erosion syndrome?
Is it possible to identify the environmental factors that could be manipulated to prevent multiple sclerosis?
Is it possible to identify what children with a visual impairment due to coloboma actually see?
Is it possible to improve vision in an eye badly affected by squint?
Is it possible to influence eye collagen production in someone suffering from Stickler Syndrome?
Is it possible to manipulate changes in air pressure to alleviate tinnitus?
Is it possible to measure the progress being made with interventions for corneal erosion syndrome?
Is it possible to offer effective treatment to maintain or improve photoreceptor function in cone dystrophy?
Is it possible to perform squint surgery where there is muscle deterioration?
Is it possible to prevent accommodative squints caused by hypermetropia and emetropisation?
Is it possible to prevent further occurrences of retinal damage caused by toxoplasmosis?
Is it possible to recover accommodation once presbyopia is evident?
Is it possible to reshape the cornea to correct the curvature for people with keratoconus ?
Is it possible to reverse the damage caused by toxoplasmosis?
Is it possible to step-down to lower dose, combination inhalers, such as Seretide or Symbicort for people with asthma?
Is it possible to surgically develop a fovea, or to artificially replace melanim in the eye to improve vision in people with ocular albinism?
Is it possible to treat a cataract in an eye with central serous retinopathy (which has not crossed the macula), without causing further damage?
Is it really necessary to take preventative medication if I only have mild asthma?
Is it safe to breastfeed on certain anti-epileptic drugs?
Is it safe to continue insulin analogues in pre conception and pregnancy in type 1 diabetes?
Is it safe to have a full body massage following Myocardial Infarction?
Is it safe to treat adults with untreated amblyopia using perceptual learning techniques?
Is it safe to use steroids in children under two with asthma? What are the side effects and will I damage my child in the long term?
Is it true that atmospheric pressure/weather influences balance disorders, and how might this best be managed?
Is joint fusion more effective than joint preserving approaches in managing ankle foot deformities in children and young people with neurodisability?
Is Keraflex likely to be an effective and low risk treatment for Keratoconus?
Is laser or diathermy ablation of endometriosis more likely to result in pregnancy in patients with subfertility?
Is laser therapy or other light therapies effective for a 40-year-old woman with rosacea on the face, who also had prior metranidazole cream and tetracycline with no success?
Is laser treatment appropriate for people with myopia and squint?
Is laser treatment effective for Hidradenitis suppurativa?
Is laser treatment recommended for the treatment of long and short sightedness?
Is lifestyle advice useful at promoting lifestyle improvements and reducing risk of stroke?
Is long term aspirin therapy beneficial for stroke caused by clot?
Is long term physiotherapy review of exercise programmes benefical after stroke?
Is long term use of moisturizers on erosions associated with adverse events from treatments for dystrophic epidermolysis bullosa?
Is low dose naltrexone (LDN) effective in slowing, stopping or reversing the accumulation of disability associated with multiple sclerosis and managing the symptoms of multiple sclerosis?
Is massaging pressure areas effective in the prevention of pressure ulcers?
Is meditation an effective tinnitus management strategy for people with tinnitus?
Is Ménière's disease triggered or exacerbated by any specific medication (and my implication is avoidance of those drugs helpful)?
Is mental-health self-help literature useful for preventing or treating depression after stroke?
Is metformin combined with insulin treatment in children and young people with type 1 diabetes better than treatment with insulin alone?
Is metformin, when added to insulin to reduce insulin resistance, effective for the treatment of type 1 diabetes?
Is mindfulness meditation an effective tinnitus management strategy?
Is monochloroacetic acid more effective for the treatment of warts than liquid nitrogen?
Is MRI suitable to use for monitoring prostate cancer as part of an Active Surveillance programme?
Is neurostimulation effective in managing a neurogenic bladder?
Is noise cancellation technology an effective treatment for tinnitus?
Is non-linguistic cognitive training effective for aphasia following stroke?
Is olanzapine dangerous in patients with hyperglycaemia?
Is once daily insulin effective in treating children and young people with type 1 diabetes?
Is once daily insulin injection regime in children and young people with type 1 diabetes, especially in pre-school children, as effective as more complicated regimens?
Is one type of splint superior to another for osteoarthritis of the carpometacarpal joint?
Is ongoing rhythm therapy effective to improve handwriting and other functioning in children and adults with Developmental Coordination Disorder or dyspraxia?
Is participation in activities (e.g. Stroke clubs, ongoing therapy) beneficial at achieving later improvement after stroke?
Is peer-support useful following hospital discharge following a stroke?
Is PEG insertion (feeding tube directly into the tummy) better than naso-gastric tubes (feeding tube via the nose) at helping people move from being 'nil-by-mouth' to being able to eat/drink following a stroke?
Is phototherapy (UVB or PUVA) an effective and safe treatment for Hidradenitis suppurativa?
Is physical therapy (electro-acupuncture, TENS and low level laser therapy) effective for osteoarthritic knee pain?
Is physiotherapy early after stroke beneficial?
Is physiotherapy effective in reducing disability in people with multiple sclerosis?
Is physiotherapy helpful for controlling asthma?
Is population screening for people with multiple sclerosis possible, available and effective for high risk groups?
Is Pranayam Yoga helpful in asthma?
Is procyclidine effective in treating tardive dyskinesia if taken in conjunction with antipsychotics?
Is prophylactic prescription of anti-emetic treatment or availability of anti-emetic treatment at the patient's home more effective in reducing nausea than the availability of prescription on request for patients starting strong opioids for the treatment of pain in advanced or progressive disease?
Is protein Z influenced by the acute phase response?
Is providing treatment for psychosis and substance misuse services within staffed accommodation more cost-effective than a combination of hospital and home treatment?
Is provision of special glasses such as those with tinted, ambient prism lenses, and ?vision therapy? effective to improve functioning in children and young people with neurodisability?
Is pseudocatalase cream combined with brief exposure to UVB light as recommended, effective in treating vitiligo?
Is psychological therapy (Cognitive Behaviour Therapy/Mindfulness Meditation) effective for people with tinnitus?
Is psychological therapy effective for children with tinnitus?
Is psychological therapy effective for people with tinnitus?
Is PUVA therapy more effective if used to treat vitiligo when it first appears, rather than waiting until the disease has spread?
Is recombinant human growth hormone (rhGH) therapy effective to improve cardiovascular effects in patients with congestive heart failure caused by left ventricular systolic dysfunction?
Is regular exercise effective in slowing, stopping or reversing the accumulation of disability associated with multiple sclerosis and reducing the frequency of relapses?
Is regular monitoring (for example; of blood pressure) by a stroke specialist nurse helpful after stroke?
Is regulation of body temperature affected by use of antiepileptic drugs?
Is relaxation an effective tinnitus management strategy for people with pulsatile tinnitus?
Is relaxation an effective tinnitus management strategy for people with tinnitus and what are the most effective techniques?
Is remifentanil a cost effective drug in anaesthesia care?
Is remifentanil Patient Controlled Analgesia (PCA) a safe alternative to epidural analgesia in the obstetric patient?
Is response to pharmacological treatment predicted more reliably by underlying aetiology or by symptom characteristics?
Is risperidone less likely than other antipsychotic drugs to cause tardive dyskinesia?
Is rituximab therapy associated with a higher rate of relapse in kidney transplant patients with post-transplant lymphoproliferative disorder?
Is selective or routine stenting in renal transplantation effective?
Is self-directed psychological counselling (via the internet) an effective strategy for the self management of tinnitus?
Is self-help group therapy an effective tinnitus management strategy?
Is self-hypnosis an effective tinnitus management strategy?
Is self-practice of repetitive, high intensity, task-specific activities beneficial to motor recovery following a stroke?
Is sitting for a small time (for example to eat a meal) likely to substantially increase pressure ulcer healing time?
Is sleep disturbance for repositioning an effective intervention in the prevention of pressure ulcers?
Is speech and language therapy helpful for patients more than 1 year after stroke?
Is staff training effective in improving pressure ulcer healing?
Is steam inhalation with essential oils an effective tinnitus management strategy?
Is stem cell therapy beneficial for recovery after stroke?
Is stem cell therapy effective in the treatment of diabetes?
Is stem cell therapy effective in the treatment of multiple sclerosis?
Is stimulation provided by relatives during open visiting effective at improving recovery after stroke?
Is stroke-specific counseling helpful after stroke?
Is surgery effective in treating Hidradenitis suppurativa?
Is surgery more effective than wound care in the treatment of difficult to heal lesions in dystrophic epidermolysis bullosa?
Is Symbicort less likely to cause mucus formation than Advair in asthma?
Is systematic banking of colostrum antenatally of any benefit in pregnancies complicated by diabetes?
Is taking aspirin beneficial for a child who has had a stroke with no known cause?
Is telemedicine useful in the prevention, treatment and rehabilitation of stroke?
Is tension free vaginal tape surgery in women with mixed incontinence associated with better outcomes than maximal conservative treatments in terms of continence and quality of life?
Is the Alexander Technique effective in improving the movement of people with Parkinson's Disease?
Is the Buteyko breathing method useful for helping me control my asthma symptoms?
Is the contraceptive pill effective in helping to manage multiple sclerosis?
Is the effect of antipsychotic medication altered by illicit drug use or excessive alcohol consumption?
Is the NICE target for patient warming of 36.0?C appropriate or would 36.5?C be better?
Is the optimum amount of daily occlusion therapy for amblyopia affected by the patient's stage of neural development?
Is the sensation of having a foreign body in the eye, such as a piece of glass or stone, a symptom of the onset of thyroid eye disease?
Is the treatment of chronic cerebrospinal venous insufficiency (CCSVI) effective for the treatment of multiple sclerosis?
Is the treatment of ovarian endometriomas by coagulation, vapourisation, excision or cystectomy associated with a significant increase in cyst recurrence?
Is the Trendelenburg system of positioning more effective than the knee break system for preventing pressure ulcers?
Is the use of anaesthetic rooms (and the transfer to theatre) an unacceptable hazard?
Is the use of antispychotic drugs in eldely patients more dangerous?
Is the use of Direct Renin Inhibitors complementary to or better than ACE/ARB in diabetic and also in non-diabetic nephropathy?
Is the use of insulin analogues associated with an increase in cancer rates?
Is the water swallow test or puree swallow test best in the assessment of swallow in acute stroke patients?
Is there a bacteria responsible for producing trimethylamine (TMA) in the gut?
Is there a blood test that can predict which infants are at risk of retinopathy of prematurity?
Is there a causative association between oral isotretinoin and depression and suicidal behaviour in acne patients?
Is there a connection between diabetes and thyroid eye disease?
Is there a connection between thyroid disease, particularly disease treated with thyroid supplements, and Age Related Macular Degeneration?
Is there a curative treatment for prostate cancer that does not destroy a man's fertility and sex life?
Is there a difference in efficacy and acceptability of three currently available topical treatments in terms of clearance of pre-cancerous actinic keratoses (AK) and persistence of clearance of AK over 1 year?
Is there a difference in quality of life between those who use basal bolus or twice daily mixed insulin regimens?
Is there a drug to prevent diabetic retinopathy?
Is there a genetic marker for prostate cancer that would be both more sensitive and more specific than PSA serum level?
Is there a genetic marker for prostate cancer that would be both more sensitive and more specific than PSA serum level?
Is there a group of children and young people with neurodisability for whom a low stimulation ward environment would substantially reduce the duration of inpatient episodes?
Is there a link between Hidradenitis suppurativa and inflammatory bowel disease?
Is there a link between Hidradenitis suppurativa and metabolic disease?
Is there a link between Hidradenitis suppurativa and other skin diseases?
Is there a link between poor diet and response to amblyopia therapy in children?
Is there a monitoring regime that will give earlier indication of the requirement /need for follow up further treatment for prostate cancer?
Is there a more accurate test than the serum B12 test for monitoring pernicious anaemia, such as monitoring B12 analogues (that which the body cannot use)?
Is there a more reliable way of distinguishing benign prostate diseases from prostate cancer to improve outcomes for those diagnosed with prostate cancer?
Is there a place for inverse occlusion in the treatment of eccentric fixation in strabismic amblyopes?
Is there a place for nitrous oxide in anaesthesia care?
Is there a potential for dependence associated with pharmacological agents for neuropathic pain?
Is there a relationship between consultation time and effective management of tinnitus?
Is there a reliable way of determining if the stomach is empty?
Is there a role for gene therapy in the treatment of patients with the genetic (heritable) form of retinoblastoma?
Is there a role for polypharmacy with B12 for treating pernicious anaemia?
Is there a role for statins in atrial fibrillation?
Is there a safe level of Vitamin A to consume or use, in order to avoid worsening of Stargardts disease?
Is there a treatment for prostate cancer that will be effective to the end of a man's normal life span?
Is there a vaccine that can prevent prostate cancer?
Is there a vaccine that can prevent prostate cancer?
Is there a way of preventing or delaying the spread of prostate cancer outside prostate gland?
Is there a way to improve screening of premature babies for retinopathy of prematurity?
Is there an alternative to eye injections for macular degeneration treatment?
Is there an effective drug to treat akathisia as a side effect of long term antipsychotic medication?
Is there an effective method of reducing frequency of flares/spread of lesions caused by Hidradenitis suppurativa?
Is there an effective way of screening for preventable vision loss from uncorrected refractive error in children, from an early age?
Is there an effective way to audit the tinnitus care pathway?
Is there an eye health care programme which could help prevent the onset of age-related macular degeneration?
Is there an increase in the number of younger men developing aggressive prostate cancer? If so, does it affect treatment outcomes?
Is there any benefit for people with Type 1 diabetes from the addition of metformin to insulin treatment?
Is there any chance of even the smallest amount of sight being restored in the foreseeable future for people with retinitis pigmentosa and complete sight loss?
Is there any detrimental effect on visual acuity in the good eye, when occlusion therapy is used to treat congenital cataract in young babies?
Is there any difference in the effects of PowerBreath and Buteyko breathing exercises in controlling asthma?
Is there any effective genetic therapy for inherited forms of deafness (and associated tinnitus)?
Is there any evidence for combination inhalers, e.g. Symbicort for people with asthma?
Is there any evidence for the effectiveness of cannabis in tinnitus treatment?
Is there any evidence for the effectiveness of Caroverine in tinnitus treatment?
Is there any evidence for the effectiveness of melatonin in reducing tinnitus?
Is there any evidence for the effectiveness of paracetamol in reducing tinnitus?
Is there any evidence for the effectiveness of using a nasal spray on tinnitus?
Is there any evidence for the use of an inhaler/oxygenation machine (Aeronair, made in Germany) or similar apparatus in the treatment of age-related macular degeneration?
Is there any evidence for the use of metronidazole gel in the treatment of fungating breast cancer? Also can it be used in conjunction with actisorb silver to reduce bacterial load?
Is there any evidence of a better cure rate for treating proven fungal toe nail infections with both oral and topical preparations?
Is there any evidence that individualising treatment for prostate cancer has benefits?
Is there any evidence that laser treatment to the macula, as a means of treatment for age-related macular degeneration, is beneficial?
Is there any evidence that prolonged use of inhaled steroids in asthma (e.g. fluticasone) causes an increased susceptibility to upper or lower respiratory tract infections?
Is there any evidence that supports consensus language/approaches within the people/health professionals educating for the care of people with asthma?
Is there any evidence to support giving the influenza vaccine to children with asthma?
Is there any evidence to support the use of silver dressing products?
Is there any information about the use of oestrogen (patches or oral forms) for the treatment of flushing in elderly men?
Is there any information on the role of postal or telephone communication in the management of asthma?
Is there any particular diet that could be beneficial to prevent further cancers following ocular melanoma?
Is there any research into the effect of long-term ingestion of pine bark extract and severe dry age-related macular degeneration?
Is there any significant difference in nutritional status between people on the different dialysis treatment modalities?
Is there any significant difference in nutritional status between people on the different dialysis treatment modalities?
Is there any significant difference in nutritional status between people on the different dialysis treatment modalities?
Is there any specific treatment to prevent drop attacks in patients with Ménière's disease?
Is there any value in treatments such as Deep Brain Stimulation (DBS) or psychosurgery for people with severe mental illness?
Is there any way of initiating self healing in Retinitis Pigmentosa?
Is there any way of ensuring more predictable results for people needing corneal grafts for keratoconus?
Is there any way to control Charles Bonnet Syndrome?
Is there anything that can be done to stop floaters persisting in cases of posterior vitreous detachment for people with Behcets disease?
Is there anything we can do to help retain eye sight in later life to minimise the effects of age-related macular degeneration?
Is there anyway of detecting a retina pre-disposed to detachment?
Is there evidence of efficacy of lutein and zeaxanthin in patients with diabetic retinopathy?
Is there evidence that any type of insulin is superior to purified pork insulin?
Is there evidence that men with prostate cancer and low PSA serum levels at diagnosis have worse outcomes?
Is there evidence that Seretide causes chest pain, foot muscle pains, insomnia, hoarseness and stomach bloating/pains?
Is there functional benefit following surgical alignment of strabismus?
Is there likely to be a new test for prostate cancer that will improve outcomes for those diagnosed?
Is there now, or will there be, any treatment for people with age-related macular degeneration and a damaged optic nerve following a stroke ?
Is there one effective model of good practice for pressure ulcer prevention?
Is thickened fluid or plain water best at stopping aspiration (choking) following a stroke?
Is thromboprophylaxis in patients in the ICU setting effective?
Is timing a critical factor in the effective use of mattresses to prevent pressure ulceration in patients with vulnerable skin?
Is tinnitus pitch matching informative for guiding treatment strategy?
Is Tinnitus Retraining Therapy effective for people with tinnitus?
Is Tinnitus Retraining Therapy effective when delivered by an ENT specialist, audiological professional or psychologist for Tinnitus?
Is Tinnitus Retraining Therapy, delivered by non-specialist, effective for people with tinnitus?
Is tissue plasminogen activator (TPA) helpful in the long-term recovery of stroke?
Is topical negative pressure therapy more or less effective than usual care in patients with grade 3 and grade 4 pressure ulcers?
Is total intravenous anaesthesia (TIVA) superior to inhalational anaesthesia?
Is trans-oesophageal echocardiography (TOE) required for all cardiac surgery cases?
Is treatment with Light Emitting Diodes (LED), and other new technologies for phototherapy be beneficial for adults with psoriasis and psoriatic arthritis?
Is urethral dilation effective in treating urge incontinence in multiple sclerosis?
Is urinary catheterisation essential in patients receiving postoperative epidural anaesthesia?
Is urinary diversion surgery more effective than indwelling catheterisation (urethral or suprapubic) for the management of a neurogenic bladder in patients with spina bifida?
Is urinary diversion surgery more effective than indwelling catheterisation (urethral or suprapubic) for the management of a neurogenic bladder in patients with spina bifida?
Is urodynamic testing prior to treatment decisions for mixed urinary incontinence associated with better continence rates and quality of life than treatment indicated by history, examination, free uroflowmetry, stress test and bladder diary?
Is using a pressure ulcer risk rating scale better than clinical judgement in preventing pressure ulcers and is there a best scale?
Is UVB light therapy more effective in treating vitiligo when it first appears, rather than waiting until the disease has spread?
Is vitamin D supplementation an effective disease modifying treatment for multiple sclerosis?
Is vitamin D3 an effective therapy for irritable bowel syndrome?
Is Xolair (omalizumab) an effective asthma medication for people with low IGE?
Ischaemic pre-conditioning for elective liver resections performed under vascular occlusion
Ischaemic preconditioning for the reduction of renal ischaemia reperfusion injury
Isoflavones for hypercholesterolaemia in adults
Isoprinosine for chronic hepatitis B
Isoprinosine versus other antiviral drugs for chronic hepatitis B
Ivabradine as adjuvant treatment for chronic heart failure
Ivermectin versus benzimidazoles for treating strongyloides infection
Janus kinase-1 and Janus kinase-2 inhibitors for treating myelofibrosis
Kangaroo mother care to reduce morbidity and mortality in low birthweight infants
Ketamine as an adjuvant to opioids for cancer pain
Ketamine for management of acute exacerbations of asthma in children
Ketogenic diet and other dietary treatments for epilepsy
Kinship care for the safety, permanency, and well-being of children removed from the home for maltreatment
Knee length versus thigh length graduated compression stockings for prevention of deep vein thrombosis in postoperative surgical patients
Knee orthoses for treating patellofemoral pain syndrome
Laceback ligatures for controlling anchorage in patients undergoing fixed orthodontic treatment
L-acetylcarnitine for fragile X syndrome
Lacosamide for neuropathic pain and fibromyalgia in adults
Lactase treated feeds to promote growth and feeding tolerance in preterm infants
Lactobacilli for maintenance of remission for Crohn's disease in children
Lactose avoidance for young children with acute diarrhoea
Lamivudine or adefovir dipivoxil alone or combined with immunoglobulin for preventing hepatitis B recurrence after liver transplantation
Lamivudine versus lamivudine and thymosin alpha-1 for e antigen-positive chronic hepatitis B
Lamivudine with or without adefovir dipivoxil for postoperative hepatocellular carcinoma
Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures
Lamotrigine for acute and chronic pain
Language skills development for those with English as a second language against using interpreters for those with schizophrenia
Lanzhou Lamb rotavirus vaccine versus placebo for the prevention of rotavirus diarrhoea
Laparoendoscopic single-site donor nephrectomy (LESS-N) versus standard laparoscopic donor nephrectomy
Laparoscopic cryotherapy for renal cancer
Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome
Laparoscopic entry techniques
Laparoscopic gastric plication for severe obesity
Laparoscopic insertion of a magnetic bead band for gastro-oesophageal reflux disease (GORD)
Laparoscopic repair for perforated peptic ulcer disease
Laparoscopic surgery for endometriosis
Laparoscopic surgery for pelvic pain associated with endometriosis
Laparoscopic surgery for presumed benign ovarian tumor during pregnancy
Laparoscopic surgery for ulcerative colitis
Laparoscopic surgical box model training for surgical trainees with limited prior laparoscopic experience
Laparoscopic surgical box model training for surgical trainees with no prior laparoscopic experience
Laparoscopic surgical box model training for surgical trainees with no prior laparoscopic experience
Laparoscopic techniques for treating pelvic pain associated with endometriosis
Laparoscopic versus open distal gastectomy for gastric cancer
Laparoscopic versus open liver resection for benign and malignant hepatic lesions in adults
Laparoscopic versus open liver resection for benign and malignant hepatic lesions in adults
Laparoscopic versus open nephrectomy for live kidney donors
Laparoscopic versus open surgery for colon cancer in elderly patients with comorbidities
Laparoscopic versus open surgery for colon cancer in obese patients
Laparoscopic versus open surgery for colon cancer in patients with tumours in the left flexure
Laparoscopic versus open surgery for colon cancer in patients with tumours in the transverse colon
Laparoscopic versus open surgery for rectal cancer
Laparoscopic versus open surgery in small bowel obstruction
Laparoscopic versus open surgical techniques for ventral or incisional hernia repair
Laparoscopic versus open total mesorectal excision for rectal cancer
Laparoscopically assisted radical vaginal hysterectomy versus radical abdominal hysterectomy for the treatment of early cervical cancer
Laparoscopic-endoscopic rendezvous versus preoperative endoscopic sphincterotomy for common bile duct stones in patients undergoing laparoscopic cholecystectomy
Laparoscopy for diagnosing resectability of disease in patients with advanced ovarian cancer
Laparoscopy for the management of acute lower abdominal pain in women of childbearing age
Laparoscopy versus laparotomy for FIGO stage I ovarian cancer
Laparoscopy versus laparotomy for the management of early stage endometrial cancer
Lapatinib for metastatic breast cancer overexpressing HER2
Laquinimod for multiple sclerosis
Large-head total hip replacement versus hemiarthroplasty after hip fracture
Larval (maggots) therapy effective in the treatment of infected diabetic foot ulcers
Laryngeal mask airway surfactant administration for prevention of morbidity and mortality in preterm infants with or at risk of respiratory distress syndrome
Laryngeal mask airway versus endotracheal tube for percutaneous dilatational tracheostomy in critically ill adult patients
Laryngeal mask airway versus endotracheal tube for percutaneous dilatational tracheostomy in critically ill patients
Laser assisted versus manual phacoemulsification for lens extraction
Laser peripheral iridoplasty for angle-closure
Laser photocoagulation for diabetic macular oedema
Laser photocoagulation for diabetic retinopathy
Laser resurfacing for treating facial acne scars
Laser therapy for retinopathy in sickle cell disease
Laser trabeculoplasty for open angle glaucoma
Laser trabeculoplasty plus topical medical treatment for open angle glaucoma
Laser treatments versus conventional, drug therapies for acne
Laser-assisted in-situ keratomileusis (LASIK) versus laser-assisted subepithelial keratectomy (LASEK) for the correction of myopia
Laser-assisted in-situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia
Lasers for caries removal in deciduous and permanent teeth
Lasers or light sources for treating port-wine stains
Late (> 7 days) postnatal corticosteroids for chronic lung disease in preterm infants
Late (>7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants
Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants
Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation
Leeches (Hirudinea) for osteoarthritis
Leflunomide for psoriasis
Lenalidomide for patients with red blood cell transfusion-dependent low- or intermediate-1-risk IPSS myelodysplastic syndromes
Length of duration of improvements associated with acupuncture treatment for migraine
Length of hospitalisation for people with severe mental illness
Length of treatment time for patients with pure sleep-related epilepsy
Lens extraction for chronic angle-closure glaucoma
Less than a month versus several months' initial antibiotic treatment for Lyme disease
Leucotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Leucotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Leukodepletion for patients undergoing heart valve surgery
Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion
Leukotriene inhibitors for bronchiolitis in infants and young children
Leukotriene receptor antagonists for atopic eczema
Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children
Leukotriene receptor antagonists in primary care at steps two and three of the national asthma guidelines
Leukotriene receptor antagonists in the treatment of nasal polyps
Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review
Levetiracetam for neuropathic pain in adults
Levetiracetam monotherapy for epilepsy
Levodopa for the treatment of restless legs syndrome
Levomepromazine for nausea and vomiting in palliative care
Levomepromazine for schizophrenia
Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery
Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery
Levonorgestrel-releasing intrauterine system for atypical endometrial hyperplasia
Levosimendin in acute heart failure
Levothyroxine or minimally invasive therapies for benign thyroid nodules
Life skills programmes for chronic mental illnesses
Lifestyle changes in women with polycystic ovary syndrome
Lifestyle factors in the prevalence and severity of urinary incontinence and overactive bladder.
Lifestyle intervention for improving school achievement in overweight or obese children and adolescents
Lifestyle intervention on the treatment of urinary incontinence
Lifestyle interventions for acute gout
Lifestyle interventions for chronic gout
Lifestyle interventions for people from black, Asian and other minority ethnic groups at different BMI and waist circumference thresholds, compared to the general population?
Lifestyle interventions for the treatment of urinary incontinence in adults
Light therapy for improving cognition, activities of daily living, sleep, challenging behaviour, and psychiatric disturbances in dementia
Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates
Limited (regional) fasciectomy for Dupuytren’s contractures of the hand
Linezolid versus vancomycin for skin and soft tissue infections
Lipid lowering efficacy of atorvastatin
Lipid lowering efficacy of rosuvastatin
Lipid-lowering agents for nephrotic syndrome
Liposomal antibiotics for Lyme disease
Liquid and fluid agents for preventing adhesions after surgery for subfertility
Listening to music for improving sleep in adults with insomnia
Lithium augmentation for depression
Local anaesthetic eye drops for prevention of pain in preterm infants undergoing screening for retinopathy of prematurity
Local anaesthetic nerve block for pain management in labour
Local anaesthetic sympathetic blockade for complex regional pain syndrome
Local anaesthetics and regional anaesthesia for preventing chronic pain after surgery
Local antibiotic and antiseptic prophylaxis in cardiac implantable electronic device implantation
Local cooling for relieving pain from perineal trauma sustained during childbirth
Local corticosteroid injections for arthritic pain
Local interventions for the management of alveolar osteitis (dry socket)
Local intramuscular transplantation of autologous mononuclear cells for critical lower limb ischaemia
Local opinion leaders: effects on professional practice and health care outcomes
Local versus general anaesthesia for carotid endarterectomy
Local versus general anaesthesia for patients undergoing pars plana vitrectomy surgery
Locomotor training for walking after spinal cord injury
Long term adverse effects of antipsychotic medication
Long term adverse effects of antipsychotic medication
Long term adverse effects of clozapine
Long term adverse effects of clozapine (Clozaril)
Long term benefit of adult aural rehabilitation programs
Long term benefit of the Epley manoeuvre for benign paroxysmal positional vertigo
Long term consequences of short term hormonal therapy for endometriosis-associated pain
Long term effectiveness of middle ear implants for hearing impairment
Long term effects of antipsychotic drugs on kidneys.
Long term effects of bilateral cochlear implants for profound deafness
Long term effects of cognitive behavioural therapy for tinnitus
Long term effects of glucocorticoid therapy for rheumatoid arthritis
Long term effects of grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children
Long term effects of grommets (ventilation tubes) for recurrent acute otitis media in children
Long term effects of pharmacological and non-pharmacological treatment for childhood attention deficit-hyperactivity disorder (ADHD)
Long term hormone therapy for perimenopausal and postmenopausal women
Long term outcomes for ultrasound-guided foam sclerotherapy for varicose veins
Long term outcomes of cochlear implantation in the first year of life
Long term outcomes of laparoscopic surgery for cancer of the upper rectum
Long term proton pump inhibitor (PPI) use and incidence of gastric premalignant lesions
Long term results of antiviral treatment for chronic hepatitis B
Long term results of medical versus surgical management for gastro-oesophageal reflux disease in adults
Long term safety of Omalizumab in the treatment of allergic rhinitis
Long term side effects of amisulpride for schizophrenia
Long term side effects of antipsychotics
Long term use of clopidogrel following ST segment elevation myocardial infarction
Long versus short course treatment with metformin and clomiphene citrate for ovulation induction in women with PCOS
Long-acting beta2-agonist in addition to tiotropium versus either tiotropium or long-acting beta2-agonist alone for chronic obstructive pulmonary disease
Long-acting beta2-agonists for chronic obstructive pulmonary disease
Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma
Long-acting FSH versus daily FSH for women undergoing assisted reproduction
Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis
Long-acting therapy for chronic obstructive pulmonary disease: an overview
Longchain polyunsaturated fatty acid supplementation in infants born at term
Longchain polyunsaturated fatty acid supplementation in preterm infants
Longer term lifestyle weight management programmes for children and young people who are obese or overweight
Long-term antibiotic treatment for Crohn's disease
Long-term antibiotic treatment for Lyme disease
Long-term antibiotics for preventing recurrent urinary tract infection in children
Long-term anticoagulation treatment with low molecular weight heparin versus a vitamin K antagonist in patients with VTE and active cancer
Long-term effect of staff education and on-the-job training on patient urinary incontinence outcomes
Long-term effectiveness of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for thiose with Peripheral arterial disease
Long-term effects of anti-vascular endothelial growth factor therapies for exudative age-related macular degeneration
Long-term effects of anti-vascular endothelial growth factor therapies for neovascular age-related macular degeneration
Long-term effects of bisphosphonates on bone quality for osteoporosis
Long-term effects of weight-reducing diets in hypertensive patients
Long-term efficacy and safety of ciclosporin (cyclosporin) for atopic eczema
Long-term efficacy and safety of oral azathioprine for atopic eczema
Long-term efficacy of autologous pancreatic islet cell transplantation (after pancreatectomy) for improved glycaemic control in patients with diabetes
Long-term efficacy of UVA1 phototherapy for acute atopic eczema
Long-term outcomes of hormonal treatment for infantile spasms
Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with mild or severe endometriosis
Long-term safety and adverse effects of ultraviolet light therapy for atopic eczema in children
Long-term safety and adverse events in topical treatments for chronic plaque psoriasis
Long-term safety of biological therapies for psoriasis, including risk of malignancies
Long-term safety of pimecrolimus and tacrolimus for atopic eczema
Long-term safety of topical corticosteroids for atopic eczema, specifically in relation to bones and eyes
Long-term safety of topical steroids for atopic eczema
Long-term safety of topical steroids for repigmentation in vitiligo
Long-term use of mild immunosuppressive agents for autoimmune and allergic problems in patients with previous or current chronic hepatitis B
Long-term value of anticholinergic drug treatment for urinary incontinence
Loop diuretics for patients receiving blood transfusions
Losigamone add-on therapy for partial epilepsy
Low bacterial diet versus control diet to prevent infection in cancer patients treated with chemotherapy causing episodes of neutropenia
Low central venous pressure to decrease blood loss and blood transfusion requirements for liver resection
Low cost versus other screening tests to detect cervical cancer or precancer in developing countries
Low dose naltrexone for induction of remission in Crohn's disease
Low dose versus standard dose isotretinoin for acne
Low glycaemic index, or low glycaemic load, diets for diabetes mellitus: long-term effects, quality of life, mortality, morbidity and cost-effectiveness.
Low intensity behavioural interventions in stepped care for obsessive compulsive disorder
Low molecular weight heparin (LMWH) compared with compression therapy for deep vein thrombosis (DVT) prophylaxis.
Low molecular weight heparin for prevention of central venous catheterization-related thrombosis in children
Low molecular weight heparin for prevention of microvascular occlusion in digital replantation
Low molecular weight heparin for prevention of microvascular occlusion in digital replantation
Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-leg immobilization
Low molecular weight heparin versus catheter-directed thrombolysis in proximal lower limb deep vein thrombosis
Low molecular weight heparin versus unfractionated heparin for perioperative thromboprophylaxis in patients with cancer
Low oxygen concentrations for embryo culture in assisted reproductive technologies
Low pressure versus standard pressure pneumoperitoneum in elective laparoscopic cholecystectomy
Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy
Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy in patients with acute cholecystitis
Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy in patients with cardiopulmonary disorders
Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birth weight infants
Low-dose Computerised tomography in early diagnosis of patients at high risk of developing lung cancer
Low-dose rate brachytherapy for men with localized prostate cancer
Lower drug dosages for urinary incontinence in older people than used in younger populations
Low-fat diets for acquired hypercholesterolaemia
Low-intensity/brief psychosocial interventions for people who self-harm
Low-molecular-weight heparin (LMWH) for thromboprophylaxis in critically ill medical-surgical patients.
Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease
Loxapine inhaler for psychosis-induced aggression or agitation
Lubiprostone for irritable bowel syndrome in male patients
Lumbar drainage of cerebrospinal fluid for aneurysmal subarachnoid haemorrhage
Lung lavage for meconium aspiration syndrome in newborn infants
Lung protective ventilation strategy for the acute respiratory distress syndrome
Lung recruitment manoeuvres for reducing respiratory morbidity in mechanically ventilated neonates
Lung volume reduction surgery for diffuse emphysema
Lurasidone versus placebo for schizophrenia
Luteal phase support for assisted reproduction cycles
Lutein or zeaxanthin for age-related macular degeneration to slow or prevent distance visual acuity loss or progression
Luteinizing hormone-releasing hormone analogue as a single agent or a combined androgen blockade agent for prostate cancer
Lycopene for the prevention of prostate cancer
Macrolide antibiotics for cystic fibrosis
Macrolides for diffuse panbronchiolitis
Magnesium for alcohol withdrawal
Magnesium for primary and secondary dysmenorrhoea
Magnesium for skeletal muscle cramps
Magnesium maintenance therapy for preventing preterm birth after threatened preterm labour
Magnesium sulphate for preventing preterm birth in threatened preterm labour
Magnesium sulphate for severe acute asthma
Magnesium sulphate for women at term for neuroprotection of the fetus
Magnesium supplementation in pregnancy
Magnesium-based interventions for people with chronic kidney disease
Magnetic Resonance Imaging (MRI) surveillance compared with mammography in women over 50 years with a personal history of breast cancer
Magnetic resonance imaging (MRI) versus computed tomography (CT) for the diagnosis of lymph node metastasis in preoperative rectal cancer
Magnetic resonance imaging, magnetic resonance arthrography and ultrasonography for assessing rotator cuff tears in people with shoulder pain for whom surgery is being considered
Maintenance agonist treatments for opiate-dependent pregnant women
Maintenance chemotherapy for ovarian cancer
Maintenance therapies for multiple myeloma
Maintenance therapy with calcium channel blockers for preventing preterm birth after threatened preterm labour
Maintenance therapy with oxytocin antagonists for inhibiting preterm birth after threatened preterm labour
Maintenance treatment with antipsychotic drugs for schizophrenia
Maintenance treatments for opiate-dependent adolescents
Male involvement for increasing the effectiveness of prevention of mother-to-child HIV transmission (PMTCT) programmes
Male versus female condoms for contraception
Mammography in combination with breast ultrasonography versus mammography for breast cancer screening in women at average risk
Managed alcohol as a harm reduction intervention for alcohol addiction in populations at high risk for substance abuse
Management of daytime enuresis in children
Management of faecal incontinence and constipation in adults with central neurological diseases
Management of gag reflex for patients undergoing dental treatment
Management of incontinence after stroke
Management of low-grade squamous intra-epithelial lesions of the uterine cervix: repeat cytology versus immediate referral to colposcopy
Management of lymphoedema following surgery for breast cancer
Management of miscarriage
Management of reported decreased fetal movements for improving pregnancy outcomes
Management of sexual dysfunction due to antipsychotic drug therapy
Management of sexual dysfunction due to antipsychotic drug therapy
Management of soft tissues for dental implants
Management of the clinically negative neck (N0) of supraglottic laryngeal carcinoma
Management of the hepatic lymph nodes during resection of liver metastases from colorectal cancer
Management of trismus induced by cancer therapies in head and neck cancer patients
Manipulative interventions (pronation versus supination) for pulled elbow in young children
Manipulative interventions for reducing pulled elbow in young children
Manipulative therapies for infantile colic
Mannitol compared with hypertonic saline for patients with cystic fibrosis
Mannitol for acute traumatic brain injury
Mannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy
Mannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy
Manual chest physiotherapy for infective exacerbations of chronic obstructive pulmonary disease
Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract
Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus phacoemulsification with posterior chamber intraocular lens for age-related cataract
Manual therapy for adolescent idiopathic scoliosis
Manual therapy for non-specific thoracic pain in adults
Manual therapy with exercise for neck pain
Marital therapy for depression
Mass drug administration for malaria
Mass media interventions for reducing mental health-related stigma
Mass media interventions for smoking cessation in adults
Massage for low back pain
Massage for mechanical neck disorders
Massage for promoting mental and physical health in typically developing infants under the age of six months
Massage therapy for atopic eczema
Massage therapy for preventing pressure ulcers
Massage, reflexology and other manual methods for pain management in labour
Mast cell stabilisers for seasonal and perennial allergic conjunctivitis
Material incentives and enablers in the management of tuberculosis
Maternal and foetal outcomes following natural vaginal versus caesarean section (c-section) delivery in carriers and women with bleeding disorders
Maternal consumption of xylitol for preventing dental decay in children
Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing atopic eczema in the child
Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child
Maternal glucose administration for facilitating tests of fetal wellbeing
Maternal hydration for increasing amniotic fluid volume in oligohydramnios and normal amniotic fluid volume
Maternal oxygen administration for fetal distress
Maternal position during caesarean section for preventing maternal and neonatal complications
Maternal positions and mobility during first stage labour
Maternal prenatal and/or postnatal n-3 fish oil supplementation for preventing allergies in early childhood
Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients
Mechanical bowel preparation for elective colorectal surgery
Mechanical clot retrieval against thrombolysis or other current methods of management for people with acute ischaemic stroke
Mechanical clot retrieval for treating acute ischaemic stroke
Mechanical dilatation of the cervix at non-labour caesarean section for reducing postoperative morbidity
Mechanical insufflation-exsufflation for people with neuromuscular disorders
Mechanical insufflation-exsufflation for people with neuromuscular disorders Morrow B, Zampoli M, van Aswegen H, Argent A. Mechanical insufflation-exsufflation for people with neuromuscular disorders (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 8. Art. No.: CD010044. DOI: 10.1002/14651858.CD010044
Mechanical methods for induction of labour
Mechanical traction for chronic neck pain
Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease
Mechanical ventilation versus no mechanical ventilation for people with severe acute asthma
Mechanical versus manual chest compressions for cardiac arrest
Media campaigns for the prevention of illicit drug use in young people
Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults
Medical and dietary interventions for preventing recurrent urinary stones in children
Medical and surgical treatment for ocular myasthenia
Medical interventions for acanthamoeba keratitis
Medical interventions for fungal keratitis
Medical interventions for high grade vulval intraepithelial neoplasia
Medical interventions for primary open angle glaucoma and ocular hypertension
Medical interventions for the prevention of platinum-induced hearing loss in children with cancer
Medical interventions for traumatic hyphema
Medical interventions for treating anthracycline-induced symptomatic and asymptomatic cardiotoxicity during and after treatment for childhood cancer
Medical interventions for treating chronic pelvic pain in women
Medical interventions for treating chronic primary angle-closure glaucoma
Medical treatment for botulism
Medical treatment for small abdominal aortic aneurysms
Medical treatments for incomplete miscarriage
Medical treatments for painful bladder syndrome (interstitial cystitis)
Medical versus surgical interventions for open angle glaucoma
Medical versus surgical termination of pregnancies less than 14 weeks' gestation
Medically assisted hydration for adult palliative care patients
Medically assisted nutrition for adult palliative care patients
Medication review in hospitalised patients to reduce morbidity and mortality
Medications for increasing milk supply in mothers expressing breastmilk for their preterm hospitalised infants
Meditation (including relaxation techniques) for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Meditation and yoga for depression
Meditation and yoga for schizophrenia
Meditation for adult patients with haematological malignancies
'Mediterranean' dietary pattern for the primary prevention of cardiovascular disease
Megavitamins for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Megestrol acetate for treatment of anorexia-cachexia syndrome
Melanocyte transplantation for repigmentation in vitiligo
Melatonin as add-on treatment for epilepsy
Melatonin for non-respiratory sleep disorders in visually impaired children
Melatonin for preoperative anxiety in adults
Melatonin for the treatment of dementia
Melatonin for women in pregnancy for neuroprotection of the fetus
Melatonin in cancer treatment Wolf E, Milazzo S, Pilkington K, Liu JP, Zwahlen M, Horneber M. Melatonin in cancer treatment (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No.: CD010145. DOI: 10.1002/14651858.CD010145
Memantine for schizophrenia
Memory Rehabilitation for people with multiple sclerosis
Mental practice for treating upper extremity deficits in individuals with hemiparesis after stroke
Mentoring adolescents to prevent drug and alcohol use
Mepolizumab versus placebo for asthma
Mesalamine (5-ASA) for the management of diverticulitis
Mesalamine for lymphocytic colitis or collagenous colitis
Mesalazine for Crohn's disease in remisson vs no treatment
Mesenchymal stromal cells (MSC) for treating immune-mediated inflammation post-transplantation and in autoimmunity
Mesh fixation with glue versus suture for recurrence and pain in Lichtenstein inguinal hernioplasty
Metal protein attenuating compounds for the treatment of Alzheimer's dementia
Metered dose inhalers versus nebulizers for aerosol bronchodilator delivery for adult patients receiving mechanical ventilation in critical care units
Metformin added to insulin therapy for type 1 diabetes mellitus in adolescents
Metformin for women who are obese during pregnancy for improving maternal and infant outcomes
Methadone at tapered doses for the management of opioid withdrawal
Methadone for cancer pain
Methadone for chronic non-cancer pain in adults
Methenamine hippurate for preventing urinary tract infections
Methods and devices for graft fixation in anterior cruciate ligament reconstruction
Methods for administering subcutaneous heparin during pregnancy
Methods for assessing pre-induction cervical ripening
Methods for blood loss estimation after vaginal birth
Methods for securing endotracheal tubes in newborn infants
Methods of decreasing infection to improve outcomes after liver resections
Methods of intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy
Methods of milk expression for lactating women
Methods of preventing bacterial sepsis and wound complications after liver transplantation
Methods of repair for obstetric anal sphincter injury
Methods of term labour induction for women with a previous caesarean section
Methods to decrease blood loss and transfusion requirements for liver transplantation
Methods to decrease blood loss during liver resection
Methods to decrease blood loss during liver resection: a network meta-analysis
Methotrexate combination therapy with non-biologic disease modifying antirheumatic drugs for treating rheumatoid arthritis in adults
Methotrexate for ankylosing spondylitis
Methotrexate for induction of remission in refractory Crohn's disease
Methotrexate for induction of remission in ulcerative colitis
Methotrexate for Lyme disease
Methotrexate for maintenance of remission in Crohn's disease
Methotrexate for maintenance of remission in Crohn's disease
Methotrexate for maintenance of remission in ulcerative colitis
Methotrexate for psoriasis
Methotrexate for treating rheumatoid arthritis
Methotrexate monotherapy and methotrexate combination therapy with traditional and biologic disease modifying anti-rheumatic drugs for rheumatoid arthritis: A network meta-analysis
Methotrexate vs other systemic non-biological or biological treatments for people with psoriasis
Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents
Methylphenidate for core and ADHD-like symptoms in children aged 6 to 18 years with autism spectrum disorders (ASDs)
Methylprednisolone for ischaemia reperfusion injury sustained during elective liver resections under vascular occlusions
Metoclopramide for migration of naso-enteral tube
Metronidazole for pain after haemorrhoid surgery
Metronidazole or tinidazole for Lyme disease
Micronutrient supplementation for children with HIV infection
Micronutrient supplementation in pregnant women with HIV infection
Micropigmentation for vitiligo
Micropressure therapy for refractory Meniere's disease
Microwave ablation for the treatment of liver metastases
Microwave ablation for treating primary lung cancer and metastases in the lung
Microwave coagulation for liver metastases
Microwave thermotherapy for benign prostatic hyperplasia
Mid-childhood (ages 6-10 years) programmes to prevent substance use and risky sexual behaviour in young people
Midwife-led continuity models versus other models of care for childbearing women
Mifamurtide for osteosarcoma
Mifamurtide in combination with other typical treatments in UK clinical practice for osteosarcoma
Mifepristone for uterine fibroids
Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Milnacipran for neuropathic pain and fibromyalgia in adults
Milnacipran versus other antidepressive agents for depression
Mind-body interventions during pregnancy for preventing or treating women's anxiety
Mind-body movement therapies for Parkinson's disease
Mindfulness-based 'third wave' cognitive and behavioural therapies versus other psychological therapies for depression
Mini-Cog for the diagnosis of Alzheimer's disease dementia and other dementias within a community setting
Minimal access drainage procedures for patients with necrotising pancreatitis
Minimal effective dose of octreotide to prevent post-ERCP pancreatitis
Minimally invasive discectomy versus microdiscectomy/discectomy for symptomatic lumbar disc herniation
Minimally invasive parathyroid surgery for hyperparathryoidism
Minimally invasive parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IOPTH) and preoperative imaging versus bilateral neck exploration for primary hyperparathyroidism in adults
Minimally invasive sling operations for stress urinary incontinence in women
Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children
Minimally invasive surgery versus radiotherapy/chemoradiotherapy for early-stage oropharyngeal carcinoma
Minimally invasive versus open surgery for reversal of tubal sterilization
Mini-Mental State Examination (MMSE) for the detection of Alzheimer's dementia and other dementias in asymptomatic and previously clinically unevaluated people aged over 65 years in community and primary care populations
Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI)
Miniport versus standard ports for elective laparoscopic cholecystectomy
Miniport versus standard ports for emergency laparoscopic cholecystectomy
Miniports versus standard ports for laparoscopic cholecystectomy
Minipunch skin grafts for repigmentation in vitiligo
Minocycline for acne vulgaris: efficacy and safety
Mirror therapy for improving motor function after stroke
Mirror therapy, graded motor imagery and virtual illusion for the management of chronic pain
Mirtazapine for depression
Mirtazapine versus other antidepressive agents for depression
Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery
Mitoxantrone for multiple sclerosis
MLN-02 for induction of remission in ulcerative colitis
Mobile clinics for women's and children's health
Mobile phone messaging for communicating results of medical investigations
Mobile phone messaging for facilitating self-management of long-term illnesses
Mobile phone messaging for preventive health care
Mobile phone messaging reminders for attendance at healthcare appointments
Mobile phone text messaging for promoting adherence to antiretroviral therapy in patients with HIV infection
Mobile phone-based interventions for improving contraception use
Mobile phone-based interventions for smoking cessation
Mobility training for increasing mobility and functioning in older people with frailty
Modafinil for excessive daytime sleepiness
Models for individual oral health promotion and their effectiveness
Modern combined oral contraceptives for pain associated with endometriosis
Modes of exercise training for intermittent claudication
Modest cooling therapies (35?C to 37.5?C) for traumatic brain injury
Modifications of the Epley (canalith repositioning) manoeuvre for posterior canal benign paroxysmal positional vertigo (BPPV)
Modifying the consistency of food and fluids for swallowing difficulties in dementia
Mohs micrographic surgery versus surgical excision for periocular basal cell carcinoma
Mometasone for asthma in adults and children
Momordica charantia for type 2 diabetes mellitus
Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI)
Monoamine oxidase B inhibitors for early Parkinson's disease
Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome
Monochromatic excimer light (MEL) for repigmentation in vitiligo
Monoclonal antibody for reducing the risk of respiratory syncytial virus infection in children
Monoclonal antibody treatment for recurrent head and neck cancer
Monoclonal CCR5 antibody for treatment of people with HIV infection
Monosodium glutamate avoidance for chronic asthma in adults and children
Monotherapy for seizure control in neonatal seizures
Monotherapy versus combination therapy used as first-line therapy for primary hypertension
Monotherapy with benzoyl peroxide or topical retinoids versus combination topical therapy in the initial treatment of mild acne
Morning versus evening induction of labour for improving outcomes
Morphine for acute decompensated heart failure
Morphine in acute coronary syndromes
Mortality and adverse effects of peginterferon alpha-2a versus peginterferon alfa-2b in treatment of chronic hepatitis C
Mortality and quality of life with protective defunctioning stoma versus no stoma protection in low anterior resection for rectal carcinoma
Mosquito larval source management for controlling malaria
Most effective probiotic treatment (species, strain, dose) for irritable bowel syndrome
Motivational interventions for drug and alcohol use in schizophrenia
Motivational interviewing for improving outcomes in youth living with HIV
Motivational interviewing for substance abuse
Moulding helmets for head shape abnormality (plagiocephaly) in babies
Moxibustion for alleviating side effects of chemotherapy or radiotherapy in cancer patients
MRI scan in addition to ultrasound for diagnosis of placenta accreta in high risk pregnancy, and likelihood of caesarean hysterectomy
MRI-guided transcutaneous focused ultrasound for uterine fibroids
MRI-guided transcutaneous focused ultrasound for uterine fibroids
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease
Mucolytics for bronchiectasis
Multi-channel cystometry for urinary incontinence or overactive bladder.
Multi-component interventions for nocturia
Multidimensional rehabilitation programmes for adult cancer survivors
Multidisciplinary biopsychosocial rehabilitation for chronic low back pain
Multidisciplinary care for adults with amyotrophic lateral sclerosis or motor neuron disease
Multidisciplinary rehabilitation after primary brain tumour treatment
Multidisciplinary rehabilitation following botulinum toxin and other focal intramuscular treatment for post-stroke spasticity
Multidisciplinary rehabilitation for adults with multiple sclerosis
Multidisciplinary rehabilitation for follow-up of women treated for breast cancer
Multifocal versus monofocal intraocular lenses after cataract extraction
Multimedia educational interventions for consumers about prescribed and over-the-counter medications
Multinutrient fortification of human breast milk for preterm infants following hospital discharge
Multiple micronutrient powders for home (point-of-use) fortification of foods in pregnant women
Multiple risk factor interventions for primary prevention of cardiovascular disease in low- and middle-income countries
Multiple versus one or more antiplatelet agents for preventing early recurrence after ischaemic stroke or transient ischaemic attack
Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers
Muscle energy technique for non-specific low-back pain
Muscle relaxants for pain management in rheumatoid arthritis
Music education for improving reading skills in children and adolescents with dyslexia
Music for stress and anxiety reduction in coronary heart disease
Music interventions for improving psychological and physical outcomes in cancer patients
Music interventions for mechanically ventilated patients
Music interventions for preoperative anxiety
Music therapy for attention deficit hyperactivity disorder (ADHD) in children and adolescents
Music therapy for depression
Music therapy for people with autism spectrum disorder
Music therapy for people with dementia
Music therapy for people with schizophrenia and schizophrenia-like disorders
Mutation-specific therapies that potentiate cystic fibrosis transmembrane conductance regulator (CFTR) function in cystic fibrosis
My 18 month-old child has very unstable asthma. What is the best treatment?
My daughter is taking olanzapine for schizophrenia. Could I give her Nytol (diphenhydramine) and olanzapine?
My daughter who has been diagnosed with asthma only seems to become wheezy when she takes her steroid inhaler. Should this be happening?
My son finds it difficult to use a spacers and masks to take his inhaled medication for his asthma. How do I know he is getting the correct dose? Are there alternatives?
My son has schizophrenia. He was on Clozapine and transferred to aripiprazole. He's now becoming unwell. Is it better to switch straight back to clozapine, taper the doses or combine the two?
My two-year old child has been taking salbutamol for asthma and it does not seem to help. Is there a better treatment?
Mycophenolate mofetil (MMF) for the treatment of connective tissue disease-associated interstitial lung disease (ILD)
Mycophenolate mofetil for relapsing-remitting multiple sclerosis
Mycophenolate mofetil versus methotrexate for prevention of acute graft-versus-host disease in patients receiving allogeneic hematopoietic stem cell transplantation
Mycophenolate mofetil versus methotrexate for prevention of graft-versus-host disease in people receiving allogeneic hematopoietic stem cell transplantation
Myomectomy of fibroids for improving chances of becoming pregnant
N-acetylcysteine for sepsis and systemic inflammatory response in adults
Naftidrofuryl for dementia
Naftidrofuryl for intermittent claudication
Nalbuphine for postoperative pain treatment in children
Naloxone for improving mortality and neurological outcomes following acute traumatic brain injury
Naloxone for opiate-exposed newborn infants
Naproxen with or without an antiemetic for acute migraine headaches in adults
Narrow band imaging versus conventional white light colonoscopy for the detection of colorectal polyps
Narrow band UVB monotherapy for repigmentation in vitiligo
Narrow excision margins versus wide excision margins on disease-specific survival of patients with primary cutaneous melanoma
Narrow-band ultraviolet B phototherapy versus broad-band ultraviolet B or psoralen-ultraviolet A photochemotherapy for psoriasis
Narrowband UVB compared to PUVA for psoriasis
Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation
Nasal saline for allergic rhinitis
Nasal versus oral route for placing feeding tubes in preterm or low birth weight infants
Nasogastric versus nasojejunal tube feeding for severe acute pancreatitis
Natalizumab (alone or in combination with other therapies) for multiple sclerosis
Natalizumab for relapsing remitting multiple sclerosis
Natural cycle in vitro fertilisation (IVF) for subfertile couples
Natural cycle IVF for subfertile couples
Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months
Nebulised hypertonic saline solution for acute bronchiolitis in infants
Nebulised surfactant in preterm infants with or at risk of respiratory distress syndrome
Nebuliser systems for drug delivery in cystic fibrosis
Nebulisers versus hand-held inhalers to deliver beta2-agonist bronchodilator drugs in non-acute asthma
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis
Nebulized epinephrine for croup in children
Nebulized hypertonic saline solution for acute bronchiolitis in infants
Neck dissection following chemo-radiotherapy in advanced head and neck squamous cell carcinoma
Nedocromil sodium for chronic asthma in children
Needle gauge and tip designs for preventing post-dural puncture headache (PDPH)
Needle size for vaccination procedures in children and adolescents
Needling for encapsulated trabeculectomy filtering blebs
Negative pressure wound therapy (NPWT) for the open abdomen
Negative pressure wound therapy for partial-thickness burns
Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus
Negative pressure wound therapy, total contact casting, hyperbaric oxygen therapy and surgical debridement for diabetic foot problems.
Neoadjuvant chemotherapy plus surgery versus surgery for cervical cancer
Neoadjuvant chemotherapy versus none for resectable gastric cancer
Neostigmine for reversal of neuromuscular block in paediatric patients
Nerve blockade for reducing the incidence of delirium
Nerve blocks for initial pain management of femoral fractures in children
Neuraminidase inhibitors for preventing and treating influenza in children
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children
Neuraminidase inhibitors for the treatment of influenza infection in people with cystic fibrosis
Neuraxial anaesthesia for lower-limb revascularization
Neuraxial blockade for the prevention of postoperative mortality and major morbidity: an overview of Cochrane systematic reviews
Neuraxial blockade for the prevention of postoperative mortality and major morbidity: an overview of Cochrane systematic reviews
Neurofeedback for attention deficit-hyperactivity disorder (ADHD)
Neuromodulation with implanted electrodes for urinary storage and voiding dysfunction in adults
Neuromodulators for pain management in rheumatoid arthritis
Neuromonics is a commercial package that combines a sound device with counselling. Is it effective for people with tinnitus?
Neuromuscular blocking agents for patients with acute respiratory distress syndrome
Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease
Neuromuscular electrical stimulation for stress urinary incontinence
Neuromuscular electrostimulation for chronic obstructive pulmonary disease
Neuroprotection for prevention and treatment of glaucoma in adults
Neuroprotection for treatment of glaucoma in adults
Neuroprotective agents i.e. memantine for Ocular Hypertension (OHT) and Chronic Open Angle Glaucoma (COAG)
Neuropsychological rehabilitation for multiple sclerosis
Neuropsychological rehabilitation for stroke
Neuropsychological tests for the diagnosis of Alzheimer's disease dementia and other dementias: a generic protocol for cross-sectional and delayed-verification studies
Neurosurgery for depressive disorders
Neurosurgical interventions for the treatment of classical trigeminal neuralgia
New entrant screening and treatment for latent tuberculosis (TB) infection
New regimens for radiotherapy with curative intent for people with lung cancer
New treatments compared to established treatments in randomized trials
Newborn screening for homocystinuria
Newer anticoagulants such as fondaparinux and ximelagatran in cancer patients with central venous catheters
Newer generation antidepressants for depressive disorders in children and adolescents
Niacin for primary and secondary prevention of cardiovascular events
Nicotine receptor partial agonists for smoking cessation
Nicotine replacement therapy for smoking cessation
Nicotine vaccines for smoking cessation
Nidotherapy for people with schizophrenia
Nipple stimulation or breastfeeding for preventing postpartum haemorrhage in the third stage of labour
Nitazoxanide for chronic hepatitis C
Nitrates for achalasia
Nitrates for acute heart failure syndromes
Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non-cardiac surgery
Nitric oxide donors for cervical ripening in first-trimester surgical abortion
Nitric oxide donors for the treatment of preterm labour
Nitric oxide donors for treating preterm labour
Nitrous oxide for colonoscopy
Nitrous oxide-based versus nitrous oxide-free general anaesthesia and accidental awareness during general anaesthesia in surgical patients
Nocturnal non-invasive positive pressure ventilation for stable chronic obstructive pulmonary disease
Noise reduction management in the neonatal intensive care unit for preterm or very low birthweight infants
Non pharmacological interventions for spasticity in multiple sclerosis
Non steroidal anti-inflammatory drugs for the prevention of colorectal adenomas
Non surgical therapy for anal fissure
Non-acoustic benefits of bone-anchored hearing aids
Non-alcoholic fatty liver disease in children
Non-antibiotic pharmaceutical treatment of acute otitis media
Non-antibiotic treatments for sore throat
Non-antiepileptic drugs for trigeminal neuralgia
Non-cardioselective beta-blockers versus placebo in stable angina for improvement of mortality
Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome
Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children
Non-drug interventions for pain in Lyme neuroborreliosis
Non-drug therapies for lower limb muscle cramps
Non-fluoride topical remineralising agents containing calcium and/or phosphate for controlling dental caries
Non-hormonal interventions for hot flushes in women with a history of breast cancer
Non-immunosuppressive treatment for IgA nephropathy
Non-invasive brain stimulation techniques for chronic pain
Non-invasive imaging to detect vertebral artery stenosis
Non-invasive positive pressure ventilation
Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema
Non-invasive positive pressure ventilation for prevention of complications after pulmonary resection in lung cancer patients
Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma
Noninvasive positive-pressure ventilation as a weaning strategy for intubated adults with respiratory failure
Non-invasive ventilation during exercise training for people with chronic obstructive pulmonary disease
Non-invasive ventilation for cystic fibrosis
Non-invasive ventilation for ventilatory failure in asthma
Non-laser light treatments versus conventional, drug therapies for acne
Nonlatex versus latex male condoms for contraception
Non-medical prescribing versus medical prescribing for acute and chronic disease management in primary and secondary care
Non-operative management versus operative management in high-grade blunt hepatic injury
Nonoperative treatment for lumbar spinal stenosis with neurogenic claudication
Non-operative versus operative treatment for blunt pancreatic trauma in children
Non-opioid drugs for pain management in labour
Non-penetrating filtration surgery versus trabeculectomy for open angle glaucoma
Non-penetrating filtration surgery versus trabeculectomy for open-angle glaucoma
Non-pharmaceutical management of respiratory morbidity in children with severe global developmental delay
Non-pharmacological and non-surgical interventions for managing retained placenta
Non-pharmacological and pharmacological interventions for primary prevention of gallbladder stones in adults
Non-pharmacological interventions for alleviating pain during orthodontic treatment
Non-pharmacological interventions for caregivers of stroke survivors
Non-pharmacological interventions for depression in adults and children with traumatic brain injury
Non-pharmacological interventions for epilepsy in people with intellectual disabilities
Non-pharmacological interventions for fatigue in rheumatoid arthritis
Non-pharmacological interventions for improving work participation in patients with inflammatory arthritis
Non-pharmacological interventions for perceptual disorders following stroke and other adult-acquired, non-progressive brain injury
Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack
Non-pharmacological interventions for preventing venous insufficiency in a standing worker population
Non-pharmacological interventions for somatoform disorders and medically-unexplained physical symptoms (MUPS) in adults
Non-pharmacological interventions for women with postpartum fatigue
Non-pharmacological interventions that allow safe wandering for people with dementia
Non-pharmacological management interventions for COPD: an overview of Cochrane systematic reviews
Non-pharmacological management of infant and young child procedural pain
Non-pharmacological treatments for constipation in children
Non-prescription (OTC) oral analgesics for acute pain- an overview of Cochrane reviews
Non-resection versus resection for an asymptomatic primary tumour in patients with unresectable Stage IV colorectal cancer
Non-selective beta agonists versus beta2-agonists for acute asthma
Non-specialist health worker interventions for the care of mental, neurological and substance-abuse disorders in low- and middle-income countries
Non-steroidal antiandrogen monotherapy compared with luteinising hormone?releasing hormone agonists or surgical castration monotherapy for advanced prostate cancer
Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery
Non-steroidal anti-inflammatory agents to induce regression and prevent the progression of cervical intraepithelial neoplasia
Nonsteroidal anti-inflammatory drugs (NSAID) and aspirin for preventing colorectal adenomas and carcinomas in general population
Nonsteroidal anti-inflammatory drugs (NSAID) and aspirin for preventing colorectal adenomas and carcinomas in patients with previous adenomas and/or genetic disposition
Nonsteroidal anti-inflammatory drugs (NSAID) and aspirin for preventing recurrence and metachronous colorectal carcinomas in patients previously treated for colorectal cancer
Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis)
Non-steroidal anti-inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults
Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy
Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies
Non-steroidal anti-inflammatory drugs for acute gout
Non-steroidal anti-inflammatory drugs for heavy menstrual bleeding
Nonsteroidal anti-inflammatory drugs for neuropathic pain
Non-steroidal anti-inflammatory drugs for pain in women with endometriosis
Non-steroidal anti-inflammatory drugs for the common cold
Non-steroidal anti-inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract surgery
Non-surgical adjunctive interventions for accelerating tooth movement in patients undergoing fixed orthodontic treatment
Non-surgical interventions for convergence insufficiency
Non-surgical interventions for human papilloma virus-positive local advanced oropharyngeal squamous cell cancer
Non-surgical interventions for the management of chronic pelvic pain
Non-surgical interventions for treating heavy menstrual bleeding (menorrhagia) in women with bleeding disorders
Normal saline versus lower-chloride solutions for kidney transplantation
Nortriptyline for neuropathic pain in adults
Notification and support for people exposed to the risk of Creutzfeldt-Jakob disease (CJD) (or other prion diseases) through medical treatment (iatrogenically)
NS1 antigen detecting assays for diagnosing acute dengue infection in people living in or returning from endemic countries
Number of embryos for transfer following in vitro fertilisation or intra-cytoplasmic sperm injection
Nurse education of parents of children with atopic eczema
Nurse versus physician-led care for the management of asthma
Nurse-led service versus doctor-led service for preoperative assessment in elective surgical patients
Nurse-led titration of angiotensin converting enzyme inhibitors, beta-adrenergic blocking agents and angiotensin receptor blockers for patients with left ventricular systolic dysfunction
Nurse-led versus doctor-led clinics in the management of childhood atopic eczema
Nurse-led versus doctor-led preoperative assessment for elective surgical patients requiring regional or general anaesthesia
Nurse-led versus doctor-led preoperative assessment for elective surgical patients requiring regional or general anaesthesia
Nursing interventions for smoking cessation
Nursing interventions to assist elders in coping with hearing impairment
Nutrient-enriched formula versus standard term formula for preterm infants following hospital discharge
Nutritional interventions for liver-transplanted patients
Nutritional interventions for preventing and treating pressure ulcers
Nutritional interventions for reducing gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy
Nutritional interventions for reducing gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy
Nutritional interventions for reducing morbidity and mortality in people with HIV
Nutritional interventions for survivors of childhood cancer
Nutritional screening for improving professional practice for patient outcomes in hospital and primary care settings
Nutritional supplementation for hip fracture aftercare in older people
Nutritional supplementation for stable chronic obstructive pulmonary disease
Nutritional support for acute kidney injury
Nutritional support for critically ill children
Nutritional support for head and neck cancer patients receiving radiotherapy
Nutritional support for liver disease
Nutritional support in children and young people with cancer undergoing chemotherapy
Occlusion for stimulus deprivation amblyopia
Occupational safety and health enforcement tools for preventing occupational diseases and injuries
Occupational safety and health regulation and legislation enforcement tools for preventing occupational diseases and injuries
Occupational therapy for care home residents with stroke
Occupational therapy for cognitive impairment in stroke patients
Octreotide for the treatment of chylothorax in neonates
Oculogyric crisis in antipsychotic treatment of schizophrenia
Oestrogen therapy compared to placebo as well as, and as a supplement to, both surgical or non-surgical management in post-menopausal women with urinary incontinence.
Oestrogen therapy for urinary incontinence in post-menopausal women
Oestrogens for treatment or prevention of pelvic organ prolapse in postmenopausal women
Oestrogens for urinary incontinence in women
Of alarms, desmopressin or tricyclic drugs, which is most effective as the first line treatment of nocturnal enuresis in children?
Ofatumumab for rheumatoid arthritis
Off-pump versus on-pump coronary artery bypass grafting for ischaemic heart disease
Olanzapine discontinuation for schizophrenia
Olanzapine for cannabis cravings or use in people with psychosis and coexisting substance misuse.
Older People's Exercise intervention in Residential and nursing Accommodation (OPERA)
Omalizumab for asthma in adults and children
Omega 3 and omega 6 fatty acids for prevention of atopic eczema
Omega 3 fatty acid for the prevention of cognitive decline and dementia
Omega 3 fatty acid supplementation for preventing and slowing the progression of age-related macular degeneration
Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease
Omega 3 fatty acids for maintenance of remission in Crohn's disease
Omega 3 fatty acids for preventing or slowing the progression of age-related macular degeneration
Omega 3 fatty acids to halt progression of age-related macular degeneration
Omega 3 fatty acids to prevent age-related macular degeneration
Omega 6 fatty acids for the primary prevention of cardiovascular disease
Omega-3 and omega-6 polyunsaturated fatty acids for dry eye syndrome
Omega-3 fatty acids for cystic fibrosis
Omega-3 fatty acids for intermittent claudication
Omega-3 fatty acids supplementation for autism spectrum disorders (ASD)
Omega-3 polyunsaturated fatty acids for non-alcoholic fatty liver disease
Omentoplasty for esophagogastrostomy after esophagectomy
Once an antipsychotic medication is started for someone for a first episode of psychosis, how long do they need to keep taking them before we can start reducing the dose or consider stopping medication?
Once daily betamethasone for atopic eczema compared to once daily "new" topical corticosteroids (mometasone furoate, fluticasone propionate, methylprednisolone aceponate)
Once diagnosed should patients with retinitis pigmentosa be regularly seen by an ophthalmologist even when there is currently nothing they can do to for the condition?
Once or twice daily versus three times daily amoxicillin with or without clavulanate for the treatment of acute otitis media
Once versus twice daily low molecular weight heparin for the initial treatment of venous thromboembolism
Once-daily versus multiple-daily dosing with intravenous aminoglycosides for cystic fibrosis
One site versus two site phacotrabeculectomy for primary open angle glaucoma
One-incision versus two-incision techniques for arthroscopically-assisted anterior cruciate ligament reconstruction in adults
One-step techniques for primary distal hypospadias in children and adolescents
One-to-one dietary interventions undertaken in a dental setting to change dietary behaviour
One-to-one psychological therapy versus group interventions for schizophrenia
Open fasciotomy for Dupuytren’s contractures of the hand
Open preperitoneal techniques versus Lichtenstein repair for elective inguinal hernias
Open release for carpal tunnel syndrome
Open retropubic colposuspension for urinary incontinence in women
Open versus laparoscopic ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis
Open, laparoscopic and robot-assisted laparoscopic radical prostatectomy for localised prostate cancer
Operational Criteria Checklist for Psychotic Illness and Affective Illness (OPCRIT+) for diagnosing schizophrenia in people with psychotic symptoms
Operative caries management in adults and children
Operative technique for the treatment of popliteal artery aneurysms
Operative versus conservative management for 'fetal distress' in labour
Opioid agonist treatment for pharmaceutical opioid dependent people
Opioid therapy for treating rheumatoid arthritis pain
Opioids compared to placebo or other treatments for chronic low-back pain
Opioids for acute pancreatitis pain
Opioids for agitation in dementia
Opioids for low back pain
Opioids for neuropathic pain
Opioids for osteoarthritis of the knee or hip
Opioids for the management of breakthrough pain in cancer patients
Opioids for the palliation of refractory breathlessness in adults with advanced disease and terminal illness
Opioids for treating dyspnoea in patients with chronic heart failure
Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy
Optical coherence tomography (OCT) to guide PCI compared against percutaneous coronary intervention (PCI) with no intravascular imaging or PCI with intravascular ultrasound.
Optical correction of refractive error for preventing and treating eye symptoms in computer users
Optical reading aids for children and young people with low vision
Optimal allergen dosage of sublingual immunotherapy for allergic rhinitis
Optimal analgesic(s) for pain after tonsillectomy in children
Optimal antibiotic treatment for early disseminated Lyme disease
Optimal antibiotic treatment for early Lyme neuroborreliosis
Optimal antibiotic treatment for late Lyme neuroborreliosis
Optimal antibiotic treatment for Lyme disease in patients presenting with erythema migrans
Optimal antiviral therapy of chronic hepatitis B
Optimal approach to pelvic floor muscle training for urinary incontinence in women
Optimal cut-off value for protein Z in the estimation of thrombotic risk
Optimal dilution of topical corticosteroids for atopic eczema
Optimal dosage of ACTH (or tetracosactide) for infantile spasms
Optimal dose of folate supplementation in treatment of psoriasis with methotrexate
Optimal dose of stereotactic radiosurgery for acoustic neuromas
Optimal dosing protocols for UVB therapy of chronic atopic eczema
Optimal dosing regime/re-treatment benefits of anti-vascular endothelial growth factor modalities in the treatment of age-related macular degeneration
Optimal duration of exclusive breastfeeding
Optimal duration of pegatheron plus ribavirin therapy for chronic hepatitis C in patients with HIV
Optimal Duration of pulmonary rehabilitation in COPD patients for quality of life and exercise capacity
Optimal duration of therapy in HBeAg-negative hepatitis B patients
Optimal follow up following recovery from an asthma attack
Optimal frequency and duration of acupuncture sessions for migraine prophylaxis
Optimal frequency of application of topical corticosteroids for atopic eczema
Optimal haemoglobin level threshold for initiating blood transfusion in patients with upper gastrointestinal bleeding
Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease
Optimal loading dose of warfarin for the initiation of oral anticoagulation
Optimal maintenance regimen after cessation of UVA1 phototherapy for acute atopic eczema
Optimal management of anticoagulated moderate-high risk patients with atrial fibrillation who present with an acute coronary syndrome and/or undergo percutaneous coronary intervention +/- stent implantation
Optimal method of diagnosis of peripheral arterial disease in patients with diabetes related foot disease
Optimal method of revascularisation of the ulcerated foot in patients with diabetes and peripheral arterial disease
Optimal patient reported outcome measurement of health related quality of life in diabetic foot patients
Optimal positron emission tomography intensity for defining the gross tumour volume of a lung tumour
Optimal primary surgical treatment for advanced epithelial ovarian cancer
Optimal ribivirin dose for chronic hepatitis C when taking in combination with pegylated interferon alpha-2a or alpha-2b
Optimal size and duration of placement of self-expanding plastic stents for benign oesophageal strictures
Optimal surgical management of vesicovaginal and/or urethrovaginal fistula
Optimal surgical procedure for obstruction from primary left colorectal carcinoma
Optimal surgical treatment for anorectal fistula
Optimal time for initiating antiretroviral therapy (ART) in HIV-infected, treatment-naive children aged 2 to 5 years old
Optimal time for initiating antiretroviral therapy (ART) in HIV-positive, treatment-naive children aged 24 to 59 months (2 to 5 years old)
Optimal timing for antiretroviral therapy initiation in patients with HIV infection and concurrent cryptococcal meningitis
Optimal timing for intravascular administration set replacement
Optimal treatment pathway for isolated calf deep vein thrombosis (DVT)
Optimal vehicle for application of topical corticosteroids for atopic eczema
Optimisation of antiretroviral therapy in HIV-infected children under 3 years of age
Optimisation of thyroid hormone dose for treatment of myxedema coma
Optimum antibiotic doses for Helicobacter pylori eradication
Optimum antibiotic treatment for Lyme arthritis
Optimum chemotherapy backbone for bevacizumab treatment of metastatic colorectal cancer
Optimum dexamethasone dosing for recovery following tonsillectomy
Optimum duration of regimens for Helicobacter pylori eradication
Optimum imfliximab introduction period for steroid withdrawal in inflammatory bowel disease
Optimum method of altered fractionated radiotherapy for head and neck cancer
Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis
Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis
Oral analgesia for relieving post-caesarean pain
Oral and sublingual immunotherapy for egg allergy
Oral and systemic steroids at different doses for acute asthma in hospitalised children
Oral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation
Oral antifungal medication for toenail onychomycosis
Oral antihistamine-decongestant-analgesic combinations for the common cold
Oral antihistamines for seasonal allergic conjunctivitis
Oral antioxidants plus phenylalanine for repigmentation in vitiligo
Oral antiplatelet therapy for acute ischaemic stroke
Oral anti-pseudomonal antibiotics for cystic fibrosis
Oral antivirals for preventing recurrence of herpes simplex virus keratitis
Oral betamimetics for maintenance therapy after threatened preterm labour
Oral calorie supplements for cystic fibrosis
Oral cobamamide for repigmentation in vitiligo
Oral contraceptive pill as a treatment in women with primary dysmenorrhoea
Oral contraceptive pill compared to nonsteroidal anti-inflammatories for treating women with primary dysmenorrhoea
Oral contraceptives containing drospirenone for premenstrual syndrome
Oral dapsone for acne
Oral decongestants alone for seasonal allergic rhinitis in adolescents and adults
Oral deferiprone for iron chelation in people with thalassaemia
Oral dextrose gel for the treatment of hypoglycaemia in newborn infants
Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of deep vein thrombosis
Oral direct thrombin inhibitors or oral factor Xa inhibitors for the treatment of pulmonary embolism
Oral evening primrose oil and borage oil for eczema
Oral fumaric acid esters for psoriasis
Oral gingko biloba extract for repigmentation in vitiligo
Oral H1 antihistamines as monotherapy for eczema
Oral health advice for people with serious mental illness
Oral health educational interventions for nursing home staff and residents
Oral herbal therapies for treating osteoarthritis
Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia
Oral immunotherapy for milk allergy
Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants
Oral levamisole as an adjuvant to vaccination for hepatitis B virus seroprotection
Oral levamisole plus mometasone furoate cream for repigmentation in vitiligo
Oral minipulses of betamethasone for repigmentation in vitiligo
Oral minipulses of betamethasone plus narrow band UVB for repigmentation in vitiligo
Oral minipulses of betamethasone plus PUVA for repigmentation in vitiligo
Oral misoprostol for induction of labour
Oral morphine for cancer pain
Oral naltrexone maintenance treatment for opioid dependence
Oral non-steroidal anti-inflammatory drug therapy for lung disease in cystic fibrosis
Oral nutritional interventions in malnourished patients with cancer for survival
Oral nutritional support of older (65 years+) medical and surgical patients after discharge from hospital
Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors
Oral phenylalanine followed by UVA for repigmentation in vitiligo
Oral pimecrolimus for psoriasis
Oral polio vaccine plus inactivated polio vaccine versus oral polio vaccine alone for reducing polio in children under two years of age
Oral Polypodium leucotomos plus narrow band UVB for repigmentation in vitiligo
Oral Polypodium leucotomos plus PUVA for repigmentation in vitiligo
Oral probiotics for infantile colic
Oral psoralens with sunlight (oral PUVAsol) for repigmentation in vitiligo
Oral rinses, mouthwashes and sprays for improving recovery following tonsillectomy
Oral steroids for long-term use in cystic fibrosis
Oral steroids for nasal polyps
Oral substitution treatment of injecting opioid users for prevention of HIV infection
Oral theophylline for stable asthma in adults
Oral traditional Chinese medication for adhesive small bowel obstruction
Oral treatments for fungal infections of the skin of the foot
Oral vaccines for preventing cholera
Oral vasodilators for primary Raynaud's phenomenon
Oral versus intravenous antibiotic treatment for febrile neutropenia in cancer patients
Oral versus intravenous steroids for treatment of relapses in multiple sclerosis
Oral xanthines as maintenance treatment for asthma in children
Oral zinc for arterial and venous leg ulcers
Oral zinc for treating diarrhoea in children
Orbital radiotherapy for adult thyroid eye disease
Organisational interventions for improving wellbeing and reducing work-related stress in teachers
Organised inpatient (stroke unit) care for stroke
Oropharyngeal dysphagia behavioral treatments -- impact of dysphagia treatment on individuals' postcancer treatments
Orthodontic treatment for bimaxillary proclination in children and adults
Orthodontic treatment for deep bite and retroclined upper front teeth in children
Orthodontic treatment for distalising upper first molars in children and adolescents
Orthodontic treatment for posterior crossbites
Orthodontic treatment for prominent lower front teeth (Class III malocclusion) in children
Orthodontic treatment for prominent upper front teeth (Class II malocclusion) in children
Oscillating devices for airway clearance in people with cystic fibrosis
Osmotic and stimulant laxatives for the management of childhood constipation
Osmotic therapies added to antibiotics for acute bacterial meningitis
Osteotomy for knee osteoarthritis
Osteotomy, compression and other modifications of surgical techniques for internal fixation of extracapsular hip fractures
Outcomes of assisted reproduction after excisional surgery with drainage and ablation of ovarian endometriomata
Outpatient versus inpatient induction of labour for improving birth outcomes
Outpatient versus inpatient treatment for acute pulmonary embolism
Ovarian function after drainage and ablation of ovarian endometriomata
Over the counter (OTC) artificial tear drops for dry eye syndrome
Over-the-counter (OTC) medications for acute cough in children and adults in ambulatory settings
Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults
Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults
Over-the-counter (OTC) treatments for acne, apart from benzoyl peroxide
Ovulation triggers in anovulatory women undergoing ovulation induction
Oxandrolone for growth-hormone treated children and adolescents with Turner syndrome
Oxcarbazepine for acute affective episodes in bipolar disorder
Oxcarbazepine for neuropathic pain
Oxcarbazepine versus phenytoin monotherapy for epilepsy
Oxycodone for neuropathic pain and fibromyalgia in adults
Oxygen therapy for acute myocardial infarction
Oxygen therapy for cystic fibrosis
Oxygen therapy for heart failure
Oxygen therapy for pneumonia in adults
Oxygen versus air for nebulising beta-agonist bronchodilators in acute asthma
Oxytocin augmentation of labour in women with epidural analgesia for reducing operative deliveries
Oxytocin infusion regimens for induction of labour
Oxytocin receptor antagonists for inhibiting preterm labour
Oxytocin versus no treatment or delayed treatment for slow progress in the first stage of spontaneous labour
Pacifier use versus no pacifier use in breastfeeding term infants for increasing duration of breastfeeding
Pacing for drug-refractory or drug-intolerant hypertrophic cardiomyopathy
Package of care for active management in labour for reducing caesarean section rates in low-risk women
Paclitaxel for maintenance chemotherapy for ovarian cancer
Padma 28 for intermittent claudication
Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondylarthritis) and gastrointestinal or liver comorbidity
Pain management for patients with an acute painful sickle cell episode
Pain management for rheumatoid arthritis and cardiovascular or renal comorbidity
Pain management for tubal sterilization by hysteroscopy
Pain management for women in labour
Pain management prior to, during and following treatment for head and neck cancer
Pain relief for women undergoing oocyte retrieval for assisted reproduction
Pain relief for women with cervical intraepithelial neoplasia undergoing colposcopy treatment
Pain-relieving agents for infant colic
Paliperidone for schizophrenia
Paliperidone palmitate for schizophrenia
Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis
Palliative care for heart failure
Palliative endobronchial brachytherapy for non-small cell lung cancer
Palliative interventions for controlling vaginal bleeding in cervical cancer
Palliative pharmacological sedation for symptom relief in terminally ill adults
Palliative surgery versus medical management for bowel obstruction in ovarian cancer
Pancreatic duct guidewire placement for biliary cannulation for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP)
Pancreatic enzymes for chronic pancreatitis
Pancreaticoduodenectomy (classic Whipple) versus pylorus-preserving pancreaticoduodenectomy (pp Whipple) for surgical treatment of periampullary and pancreatic carcinoma
Pantothenic acid (vitamin B5) for acne
Paracervical local anaesthesia for cervical dilatation and uterine intervention
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm and/or low-birth-weight infants
Paracetamol (acetaminophen) for prevention or treatment of pain in newborns
Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adults
Paracetamol for low back pain
Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy
Parathyroid hormone alone or in combination with antiresorptive therapy for bone mineral density
Parathyroid hormone for the treatment of osteoporosis
Parathyroidectomy for chronic kidney disease-mineral and bone disorder (CKD-MBD)
Parent training interventions for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years
Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation
Parenteral fluid regimens for improving functional outcome in acute stroke patients
Parenteral opioids for maternal pain relief in labour
Parenteral versus oral iron therapy for adults and children with chronic kidney disease
Parent-infant psychotherapy for improving parental and infant mental health
Parenting interventions for the prevention of unintentional injuries in childhood
Parent-mediated early intervention for young children with autism spectrum disorders (ASD)
Paroxetine depression
Paroxetine versus other anti-depressive agents for depression
Partial breast irradiation for early breast cancer
Partial exchange transfusion to prevent neurodevelopmental disability in infants with polycythemia
Partial liquid ventilation for preventing death and morbidity in adults with acute lung injury and acute respiratory distress syndrome
Partial liquid ventilation for the prevention of mortality and morbidity in paediatric acute lung injury and acute respiratory distress syndrome
Partially hydrolyzed whey protein formula for preventing atopic eczema in infants
Participation in environmental enhancement and conservation activities for health and well-being in adults
Passive immunisation with monoclonal anti-Abeta antibodies for the treatment of Alzheimer's disease
Passive movements for the treatment and prevention of contractures
Patellar taping for patellofemoral pain syndrome in adults
Patellar tendon versus hamstring tendon autograft for anterior cruciate ligament rupture in adults
Pathogen-reduced platelets for the prevention of bleeding
Patient adherence to treatment in heart failure
Patient controlled intravenous analgesia versus epidural analgesia for pain following intra-abdominal surgery
Patient education and counselling for promoting adherence to treatment for tuberculosis
Patient education for chronic low back pain
Patient education for neck pain
Patient education for preventing diabetic foot ulceration
Patient education in the management of coronary heart disease
Patient education of prostate cancer to improve outcomes
Patient education on multifactorial genetic conditions for those at risk, and effect on knowledge, psychological measures and treatment uptake
Patient information on treatment options for urinary incontinence to improve access to appropriate care
Patient level factors associated with benefit of kidney transplantation for outcomes other than mortality
Patient positioning (mobilisation) and bracing for pain relief and spinal stability in metastatic spinal cord compression in adults
Patient related outcome measures for follow-up after gynaecological cancer treatment
Patient-adjusted versus health professional-adjusted insulin dosing for type 2 diabetes mellitus
Patient-initiated appointment systems for people with chronic conditions in secondary care
Patient-reported outcome measures for follow-up after gynaecological cancer treatment
Patients on antidiabetic medication testing false positive for recreational drugs
Paying for performance to improve the delivery of health interventions in low- and middle-income countries?
Payment methods for ambulatory care facilities
Payment methods for hospitals
Pedicle screw constructs in adolescent idiopathic scoliosis
Pedicle screw fixation for traumatic fractures of the thoracic and lumbar spine
Peer mentor programmes to increase the number of people at increased risk of hepatitis B and C, who are then tested and treated
Peer support for improving service engagement for people with psychosis and coexisting substance misuse
Peer support for schizophrenia
Peer support interventions for family carers of adults with chronic mental or physical illness who are living at home
Peer support interventions in people with psychosis and schizophrenia
Peginterferon alpha-2a versus peginterferon alpha-2b for chronic hepatitis C
Peginterferon plus ribavirin versus interferon plus ribavirin for chronic hepatitis C
Peginterferon plus ribavirin versus no treatment for chronic hepatitis C in patients with HIV
Pegylated granulocyte colony stimulating factor versus non-pegylated granulocyte colony stimulating factor for patients after hematopoietic stem cell transplantation
Pegylated granulocyte colony stimulating factor versus non-pegylated granulocyte colony stimulating factor for peripheral stem cell mobilization
Pegylated interferon alpha-2a plus ribavirin vs pegylated interferon alpha-2b plus ribavirin for chronic hepatitis C
Pegylated interferon and ribavirin in liver transplant candidates and recipients with HCV cirrhosis
Pegylated liposomal doxorubicin for first-line treatment of epithelial ovarian cancer
Pegylated liposomal doxorubicin for relapsed epithelial ovarian cancer
Pelargonium sidoides extract for treating acute respiratory tract infections
Pelvic artery catheterisation and embolisation in women with placenta accreta undergoing caesarean section, for uterine conservation and reduced maternal morbidity
Pelvic floor exercise to treat urinary incontinence in men after prostate surgery
Pelvic floor exercises for urge urinary incontinence.
Pelvic floor muscle function and bladder training for primary prevention of urinary incontinence in older adults
Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary incontinence in women
Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary incontinence in women
Pelvic floor muscle training as part of prenatal care to prevent incontinence
Pelvic floor muscle training compared with another active treatment for urinary incontinence in adults
Pelvic floor muscle training for men post-prostatectomy
Pelvic floor muscle training for overactive bladder (OAB) symptoms
Pelvic floor muscle training for prevention and treatment of urinary and faecal incontinence in antenatal and postnatal women
Pelvic floor muscle training for women with stress urinary incontinence
Pelvic floor muscle training in combination with another therapy compared with the other therapy alone for urinary incontinence in women
Pelvic floor muscle training in combination with another therpay compared with the other therapy alone
Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women
Pemetrexed disodium in combination with cisplatin versus other cytotoxic agents or supportive care for the treatment of malignant pleural mesothelioma
Penetrating keratoplasty versus deep anterior lamellar keratoplasty for treating keratoconus
Penicinillamine for Wilson's disease
Pentoxifylline compared to medical treatment or surgery in women with subfertility and endometriosis
Pentoxifylline for alcoholic hepatitis
Pentoxifylline for diabetic kidney disease
Pentoxifylline for endometriosis
Pentoxifylline for intermittent claudication
Pentoxifylline for the prevention of bronchopulmonary dysplasia in preterm infants
Pentoxifylline for treating venous leg ulcers
Pentoxyfilline as a treatment for proteinuria
People with tinnitus would like to know about the effectiveness of devices in reducing tinnitus
Perampanel add-on for drug-resistant partial epilepsy
Perazine for schizophrenia
Percussion, diuresis, and inversion therapy for the passage of lower pole kidney stones following shock wave lithotripsy
Percutaneous acetic acid injection for early hepatocellular carcinoma
Percutaneous balloon cryoablation for treating atrial fibrillation
Percutaneous cholecystostomy for high-risk surgical patients with acute calculous cholecystitis
Percutaneous coronary intervention versus coronary artery bypass grafting for adults with diabetes and multivessel coronary disease
Percutaneous cryotherapy for renal cancer
Percutaneous electrical nerve stimulation (PENS) for refractory neuropathic pain
Percutaneous endoscopic catheter laser balloon pulmonary vein isolation for atrial fibrillation (AF)
Percutaneous endoscopic gastrostomy versus nasogastric tube feeding for adults with swallowing disturbances
Percutaneous ethanol injection for early hepatocellular carcinoma
Percutaneous ethanol injection for liver metastases
Percutaneous fasciotomy for Dupuytren’s contractures of the hand
Percutaneous needle aspiration, injection, and reaspiration with or without benzimidazole coverage for uncomplicated hepatic hydatid cysts
Percutaneous pinning for distal radial fractures in adults
Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis
Percutaneous transluminal angioplasty for treatment of chronic cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis patients
Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis
Percutaneous transluminal rotational atherectomy for coronary artery disease
Perflouro alkoxy plastic versus metal palliative biliary stents for obstructing pancreatic carcinoma
Performance measures and outcome in chronic heart failure
Perfusion techniques for liver retrieval in liver donors
Perianal injectable bulking agents as treatment for faecal incontinence in adults
Pericyazine for schizophrenia
Pericyazine for schizophrenia
Peri-implantation glucocorticoid administration for assisted reproductive technology cycles
Perineal dilators for facilitating the second stage of labour
Perineal techniques during the second stage of labour for reducing perineal trauma
Periodontal treatment (scaling, root planning, oral hygiene education) versus no treatment in pregnant women with periodontitis for reducing stillbirth, preterm birth and low birth weight
Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery
Perioperative antibiotics to prevent infection after first-trimester abortion
Perioperative blood transfusions and recurrence of colorectal cancer
Perioperative buffered versus non-buffered fluid administration for surgery in adults
Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach, gastroesophageal junction, and lower esophagus
Perioperative corticosteroids for preventing complications following facial plastic surgery
Perioperative corticosteroids for preventing complications following facial plastic surgery
Perioperative dexmedetomidine for acute pain after abdominal surgery in adults
Perioperative enhanced recovery programmes for gynaecological cancer patients
Perioperative fluid volume optimization following proximal femoral fracture
Perioperative glycaemic control for diabetic patients undergoing surgery
Peri-operative glycaemic control regimens for preventing surgical site infections in adults
Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery
Perioperative interventions for smoking cessation in hip and knee arthroplasty for osteoarthritis and other non-traumatic diseases
Perioperative local anaesthesia for reducing pain following tonsillectomy
Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty
Perioperative nutrition for the treatment of bladder cancer by radical cystectomy
Perioperative nutrition interventions for women with ovarian cancer
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery
Perioperative transversus abdominis plane (TAP) blocks for analgesia after abdominal surgery
Peripheral iridotomy for pigmentary glaucoma
Peripheral nerve blocks for postoperative pain after major knee surgery
Peripheral venous blood gas analysis versus arterial blood gas analysis for the diagnosis of respiratory failure and metabolic disturbance in adults
Peritoneal closure versus no peritoneal closure for decreasing wound complications after non-obstetric abdominal operations
Peritoneal closure versus no peritoneal closure for patients undergoing non-obstetric abdominal operations
Permissive hypercapnia for the prevention of morbidity and mortality in mechanically ventilated newborn infants
Permissive hypoxaemia versus normoxaemia for mechanically ventilated critically ill patients
Permissive hypoxaemia versus normoxaemia for mechanically ventilated critically ill patients
Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in patients with stroke or transient ischaemic attack
Person centred counselling for psychosis
Personalised care planning for adults with chronic or long-term health conditions
Personalised risk communication for informed decision making about taking screening tests
Personalised support services for adults with severe mental illness
Personally-tailored activities for improving psychosocial outcomes for people with dementia in community settings
Person-directed non-pharmacological interventions for preventing and treating sleepiness and sleep disturbances caused by shift work
Pessaries (mechanical devices) for pelvic organ prolapse in women
Phacoemulsification with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract
Pharmacist-led interventions for adults with asthma or COPD
Pharmacologic and radiotherapeutic interventions for advanced pancreatic cancer
Pharmacologic interventions for preventing and treating periprosthetic osteoporosis following total hip arthroplasty
Pharmacologic interventions for treating phantom limb pain
Pharmacologic treatment for memory disorder in multiple sclerosis
Pharmacologic treatment of depression in multiple sclerosis
Pharmacologic treatment to prevent fractures in people with low bone density or osteoporosis
Pharmacological agents for preventing inadvertent perioperative hypothermia
Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation
Pharmacological interventions for ADHD symptoms in children with fetal alcohol spectrum disorders (FASD)
Pharmacological interventions for adjustment disorders in adults
Pharmacological interventions for clozapine-induced hypersalivation
Pharmacological interventions for depression in people with traumatic brain injury
Pharmacological interventions for drug-using offenders
Pharmacological interventions for epilepsy in people with intellectual disabilities
Pharmacological interventions for hypertension in children
Pharmacological interventions for improving respiratory function in amyotrophic lateral sclerosis
Pharmacological interventions for pain for life-limiting conditions in children and adolescents
Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)
Pharmacological interventions for preventing recurrent urinary stones in adults and children
Pharmacological interventions for prevention or treatment of postoperative pain in people undergoing laparoscopic cholecystectomy.
Pharmacological interventions for pruritus in adult palliative care patients
Pharmacological interventions for recurrent abdominal pain in childhood
Pharmacological interventions for reducing weight gain in schizophrenia
Pharmacological interventions for self-injurious behaviour in adults with intellectual disabilities
Pharmacological interventions for smoking cessation: an overview and network meta-analysis
Pharmacological interventions for somatoform disorders in adults
Pharmacological interventions for the prevention of insufficiency fractures and avascular necrosis associated with pelvic radiotherapy in adults
Pharmacological interventions for the primary prevention of gallbladder stones in adults
Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease
Pharmacological interventions for treating acute hyperkalaemia in adults
Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy
Pharmacological interventions for treatment-resistant depression in adults
Pharmacological interventions for unilateral spatial neglect after stroke
Pharmacological interventions other than botulinum toxin for spasticity after stroke
Pharmacological maintenance therapy in pregnant women with an opiate dependency
Pharmacological monotherapy compared with combination therapy for treating neuropathic pain
Pharmacological therapies for maintenance treatments of opium dependence
Pharmacological therapy for idiopathic lumbosacral plexopathy
Pharmacological treatment for antipsychotic-related constipation
Pharmacological treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children with comorbid tic disorders
Pharmacological treatment for Buerger's disease
Pharmacological treatment for depression during opioid agonist treatment for opioid dependence
Pharmacological treatment for Kleine-Levin Syndrome
Pharmacological treatment for memory disorder in multiple sclerosis
Pharmacological treatment for pain in Guillain-Barre syndrome
Pharmacological treatment for psychotic depression
Pharmacological treatment for the prevention of vestibular migraine
Pharmacological treatment of depression in patients with a primary brain tumour
Pharmacological treatment of depression in patients with a primary brain tumour
Pharmacological treatment of pediatric headaches
Pharmacological treatment of vascular risk factors for reducing mortality and cardiovascular events in patients with abdominal aortic aneurysm
Pharmacological treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for Guillain Barr? syndrome
Pharmacological treatments for fatigue associated with palliative care
Pharmacological treatments for preventing epilepsy following traumatic head injury
Pharmacotherapies for sleep disturbances in Alzheimer's disease
Pharmacotherapy combined with behavioural support and delivered by health professionals compared to brief advice, behavioural support or pharmacotherapy alone vs smokeless tobacco
Pharmacotherapy for bipolar disorder in older people
Pharmacotherapy for hyperuricemia in hypertensive patients
Pharmacotherapy for mild hypertension
Pharmacotherapy for the prevention of chronic pain after surgery in adults
Pharmacotherapy for thyroid nodules
Pharmacotherapy for trichotillomania
Pharyngeal instillation of surfactant before the first breath for prevention of morbidity and mortality in preterm infants at risk of respiratory distress syndrome
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures
Phenytoin for neuropathic pain and fibromyalgia in adults
Phenytoin versus valproate monotherapy for partial onset seizures and generalised onset tonic-clonic seizures
Phlebotonics for haemorrhoids
Phonics training for English-speaking poor readers
Phosphate binders for preventing and treating bone disease in chronic kidney disease patients
Phosphodiasterase III inhibitors for chronic asthma
Phosphodiasterase IV inhibitors for chronic asthma
Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease
Phosphodiesterase inhibitors for lower urinary tract symptoms consistent with benign prostatic hyperplasia
Photodynamic therapy for recurrent head and neck cancer
Photodynamic therapy for recurrent respiratory papillomatosis
Photodynamic therapy using 5-ALA versus porfimer sodium for Barrett's oesophagus
Photorefractive keratectomy (PRK) versus laser assisted in situ keratomileusis (LASIK) for hyperopia correction
Phototherapy for treating pressure ulcers